Research Topics
Species | Til WykesSummaryAffiliation: King's College London Country: UK Publications
| Collaborators
|
Detail Information
Publications
A meta-analysis of cognitive remediation for schizophrenia: methodology and effect sizesTil Wykes
Institute of Psychiatry, King s College London, UK
Am J Psychiatry 168:472-85. 2011..The present meta-analysis will determine the effects of treatment and whether study method or potential moderators influence the estimates...
Working alliance and its relationship to outcomes in a randomized controlled trial (RCT) of antipsychotic medicationTil Wykes
NIHR MHRN and Institute of Psychiatry, King s College London, De Crespigny Park, London SE5 8AF, UK
BMC Psychiatry 13:28. 2013..Long acting injections (LAI) have been associated with perceptions of coercion in cross sectional studies but there have been no longitudinal studies of the effects on clinical relationships with newer depot medications...- Developing models of how cognitive improvements change functioning: mediation, moderation and moderated mediationTil Wykes
King s College London, Institute of Psychiatry, London SE5 8AF, UK
Schizophr Res 138:88-93. 2012..Cognitive remediation (CRT) affects functioning but the extent and type of cognitive improvements necessary are unknown... - A multi-centre, randomised controlled trial of cognitive therapy to prevent harmful compliance with command hallucinationsMax Birchwood
School of Psychology, University of Birmingham, Edgbaston, B15 2TT, Birmingham, UK
BMC Psychiatry 11:155. 2011..A cognitive therapy grounded in the principles of the Social Rank Theory, is being evaluated in terms of its effectiveness in reducing harmful compliance with command hallucinations... - Does age matter? Effects of cognitive rehabilitation across the age spanTil Wykes
King s College, Institute of Psychiatry London, UK
Schizophr Res 113:252-8. 2009..Cognitive remediation (CR) therapy in its various disguises can be helpful for people with schizophrenia but it is not clear if patient characteristics are likely to interfere with its effectiveness... - Thinking about the future cognitive remediation therapy--what works and could we do better?Til Wykes
Institute of Psychiatry, King s College London, London SE5 8AF, UK
Schizophr Bull 37:S80-90. 2011.... 
Cognitive remediation therapy (CRT) for young early onset patients with schizophrenia: an exploratory randomized controlled trialTil Wykes
Institute of Psychiatry, Kings College London, De Crespigny Park, London, SE5 8AF, UK
Schizophr Res 94:221-30. 2007..The objective of this study is to evaluate the efficacy of CRT in alleviating cognitive deficits compared to treatment as usual and explore the mediating and moderating effects of cognitive improvement...- Cognitive remediation therapy in schizophrenia: randomised controlled trialTil Wykes
Department of Psychology, Kings College London, Institute of Psychiatry, London, UK
Br J Psychiatry 190:421-7. 2007..Cognitive difficulties are prevalent in people with a diagnosis of schizophrenia and are associated with poor long-term functioning... - Cognitive remediation therapy in schizophrenia: cost-effectiveness analysisAnita Patel
Centre for the Economics of Mental Health, Health Service and Population Research Department, Box 24, Institute of Psychiatry, King s College London, De Crespigny Park, London SE5 8AF, United Kingdom
Schizophr Res 120:217-24. 2010..There is a lack of evidence on the cost-effectiveness of cognitive remediation therapy (CRT)... - VOICE: developing a new measure of service users' perceptions of inpatient care, using a participatory methodologyJo Evans
Health Service and Population Department, Institute of Psychiatry, Kings College London, London, UK
J Ment Health 21:57-71. 2012..Traditionally, satisfaction with acute care has been assessed using measures designed by clinicians or academics... - Are the effects of cognitive remediation therapy (CRT) durable? Results from an exploratory trial in schizophreniaTil Wykes
Department of Psychology, Institute of Psychiatry, De Crespigny Park, SE5 8AF, London, UK
Schizophr Res 61:163-74. 2003..At the end of treatment, CRT conferred a benefit to people with schizophrenia in cognition and self-esteem [Schizophr. Bull. 25 (1999) 291]. This study investigates these outcomes 6 months after the therapies were withdrawn... - Effect of a medication management training package for nurses on clinical outcomes for patients with schizophrenia: cluster randomised controlled trialRichard Gray
PO 30, Health Services Research Department, Institute of Psychiatry, De Crespigny Park, London SE5 8AF
Br J Psychiatry 185:157-62. 2004..Non-compliance attenuates the efficacy of treatments for physical and mental disorders... - Schizophrenia patients with cognitive deficits: factors associated with costsAnita Patel
Centre for the Economics of Mental Health, Institute of Psychiatry, King s College London, De Crespigny Park, London, UK
Schizophr Bull 32:776-85. 2006..Further investigation in larger samples is needed to confirm this finding and to explore its generalizability to those with less severe deficits... - Cognitive remediation for schizophrenia: it is even more complicatedTil Wykes
Department of Psychology, Institute of Psychiatry, King s College London, London, UK
Curr Opin Psychiatry 22:161-7. 2009..This review summarizes findings of induced cognitive change in schizophrenia, with reference to the remediation method, the presence of accompanying treatment(s), how cognitive change generalizes and its value... - Different components of metacognition and their relationship to psychotic-like experiencesClare Reeder
Institute of Psychiatry, King s College London, UK
Behav Cogn Psychother 38:49-57. 2010..However, studies offering supporting evidence have failed to distinguish between metacognitive beliefs about the consequences of having certain thoughts, and metacognitive beliefs about one's own cognitive skills... - Can't surf, won't surf: the digital divide in mental healthLiam Ennis
Health Services and Population Research Department, Institute of Psychiatry, London, UK
J Ment Health 21:395-403. 2012..However, there is a danger that those who do not use or have access to technology will not benefit from HIT innovations, thus creating a "digital divide"... - Effects on the brain of a psychological treatment: cognitive remediation therapy: functional magnetic resonance imaging in schizophreniaTil Wykes
Department of Psychiatry, Institute of Psychiatry, London, UK
Br J Psychiatry 181:144-52. 2002..The results of one randomised control trial testing a psychological rehabilitation programme aimed at information processing strategies showed improvements in cognition post-treatment... - Which executive skills should we target to affect social functioning and symptom change? A study of a cognitive remediation therapy programClare Reeder
Department of Psychology, Institute of Psychiatry, London, UK
Schizophr Bull 30:87-100. 2004..Regardless of treatment type, increased response inhibition speed was associated with reduced negative symptoms. Stimulus-driven responding and response inhibition speed may therefore make useful targets for intervention... - Cognitive predictors of social functioning improvements following cognitive remediation for schizophreniaClare Reeder
Department of Psychology, Institute of Psychiatry, Kings College, De Crespigny Park, London SE5 8AF, UK
Schizophr Bull 32:S123-31. 2006..Improvement in the ability to generate new schemas has a beneficial impact on social functioning... - Close to the bench as well as at the bedside: involving service users in all phases of translational researchFelicity Callard
Stakeholder Participation Theme, NIHR Biomedical Research Centre for Mental Health, South London and Maudsley NHS Foundation Trust and Institute of Psychiatry, King s College London, London, UK
Health Expect 15:389-400. 2012..The paper aims to develop a model of translational research in which service user and other stakeholder involvement are central to each phase... - A model for developing outcome measures from the perspectives of mental health service usersDiana Rose
Service User Research Enterprise, Institute of Psychiatry, King s College London, UK
Int Rev Psychiatry 23:41-6. 2011..The final measure is subject to psychometric testing both to ensure it is robust and to explore similarities and differences with conventionally derived measures... - The self or the voice? Relative contributions of self-esteem and voice appraisal in persistent auditory hallucinationsDominic Fannon
Division of Psychological Medicine and Psychiatry, Institute of Psychiatry, Kings College London, Denmark Hill, London, UK
Schizophr Res 112:174-80. 2009..It was hypothesized that low self-esteem is prominent in, and contributes to, depression in voice hearers... - Cognitive behavior therapy for schizophrenia: effect sizes, clinical models, and methodological rigorTil Wykes
Department of Psychology, Institute of Psychiatry, King s College London, London, UK
Schizophr Bull 34:523-37. 2008..But recent advances have widened the CBTp targets to other symptoms and have different methods of provision, eg, in groups... - A comparison of participant information elicited by service user and non-service user researchersDiana Rose
Institute of Psychiatry, King s College London, De Crespigny Park, London SE5 8AF, United Kingdom
Psychiatr Serv 62:210-3. 2011..The study examined whether data collected by researchers who were service users differed from data collected by non-service user researchers in a study that measured perceived coercion... - What are the effects of group cognitive behaviour therapy for voices? A randomised control trialTil Wykes
Department of Psychology, Institute of Psychiatry, Kings College London, United Kingdom
Schizophr Res 77:201-10. 2005..This study tested whether a group based on cognitive behavioural principles could produce beneficial effects on hallucinations... - Executive functioning in schizophrenia and the relationship with symptom profile and chronicityKathryn E Greenwood
Department of Psychology, Institute of Psychiatry, London, United Kingdom
J Int Neuropsychol Soc 14:782-92. 2008..The executive profile, therefore, is related to symptom type rather than chronicity... - Negative symptoms and specific cognitive impairments as combined targets for improved functional outcome within cognitive remediation therapyKathryn E Greenwood
Department of Psychology, Institute of Psychiatry, London
Schizophr Bull 31:910-21. 2005..Both cognitive processes and negative symptoms should be targeted in cognitive remediation to effect the greatest change in community functions... - Effects of Age and Cognitive Reserve on Cognitive Remediation Therapy Outcome in Patients With SchizophreniaDimitris Kontis
Department of Psychology, King s College London, Institute of Psychiatry London, United Kingdom Electronic address
Am J Geriatr Psychiatry 21:218-30. 2013..Older people with a diagnosis of schizophrenia seem to show fewer benefits following cognitive remediation therapy (CRT). It is not clear whether cognitive reserve modifies the relationship with age... - No association between the Catechol-O-Methyltransferase (COMT) val158met polymorphism and cognitive improvement following cognitive remediation therapy (CRT) in schizophreniaKathryn Greenwood
Institute of Psychiatry, King s College London, UK
Neurosci Lett 496:65-9. 2011..A complex set of factors may influence cognitive change, however, such that the COMT genotype might still have a subtle effect on response to CRT or similar interventions... - Patients' perspectives on electroconvulsive therapy: systematic reviewDiana Rose
Service User Research Enterprise, PO34, Institute of Psychiatry, De Crespigny Park, London SE5 8AF
BMJ 326:1363. 2003..To ascertain patients' views on the benefits of and possible memory loss from electroconvulsive therapy... - Rapid progress or lengthy process? Electronic personal health records in mental healthLiam Ennis
Health Services and Population Research Department, Institute of Psychiatry, London SE5 8AF, UK
BMC Psychiatry 11:117. 2011..Special attention is paid to the concept of 'empowerment' and what this means in relation to ePHRs... - The effect of medication management training on community mental health nurse's clinical skillsRichard Gray
Health Services Research Department, Institute of Psychiatry, De Crespigny Park, SE5 8AF, London, UK
Int J Nurs Stud 40:163-9. 2003..Conclusions. In this uncontrolled study training improved the medication management skills of CMHNs...