T Wykes

Summary

Affiliation: King's College London
Country: UK

Publications

  1. ncbi request reprint Effects on the brain of a psychological treatment: cognitive remediation therapy: functional magnetic resonance imaging in schizophrenia
    Til Wykes
    Department of Psychiatry, Institute of Psychiatry, London, UK
    Br J Psychiatry 181:144-52. 2002
  2. ncbi request reprint More than just a place to talk: young people's experiences of group psychological therapy as an early intervention for auditory hallucinations
    Elizabeth Newton
    University College, London, UK
    Psychol Psychother 80:127-49. 2007
  3. ncbi request reprint Cognitive remediation therapy in schizophrenia: randomised controlled trial
    Til Wykes
    Department of Psychology, Kings College London, Institute of Psychiatry, London, UK
    Br J Psychiatry 190:421-7. 2007
  4. ncbi request reprint Cognitive remediation therapy (CRT) for young early onset patients with schizophrenia: an exploratory randomized controlled trial
    Til Wykes
    Institute of Psychiatry, Kings College London, De Crespigny Park, London, SE5 8AF, UK
    Schizophr Res 94:221-30. 2007
  5. doi request reprint Cognitive remediation for schizophrenia: it is even more complicated
    Til Wykes
    Department of Psychology, Institute of Psychiatry, King s College London, London, UK
    Curr Opin Psychiatry 22:161-7. 2009
  6. pmc Cognitive behavior therapy for schizophrenia: effect sizes, clinical models, and methodological rigor
    Til Wykes
    Department of Psychology, Institute of Psychiatry, King s College London, London, UK
    Schizophr Bull 34:523-37. 2008
  7. ncbi request reprint Are the effects of cognitive remediation therapy (CRT) durable? Results from an exploratory trial in schizophrenia
    Til Wykes
    Department of Psychology, Institute of Psychiatry, De Crespigny Park, SE5 8AF, London, UK
    Schizophr Res 61:163-74. 2003
  8. ncbi request reprint What are the effects of group cognitive behaviour therapy for voices? A randomised control trial
    Til Wykes
    Department of Psychology, Institute of Psychiatry, Kings College London, United Kingdom
    Schizophr Res 77:201-10. 2005
  9. ncbi request reprint Is it time to develop a new cognitive therapy for psychosis--cognitive remediation therapy (CRT)?
    T Wykes
    Kings College London, UK
    Clin Psychol Rev 21:1227-56. 2001
  10. ncbi request reprint The prevalence and stability of an executive processing deficit, response inhibition, in people with chronic schizophrenia
    T Wykes
    Department of Psychology, Institute of Psychiatry, De Crespigny Park, SE5 8AF, London, UK
    Schizophr Res 46:241-53. 2000

Detail Information

Publications45

  1. ncbi request reprint Effects on the brain of a psychological treatment: cognitive remediation therapy: functional magnetic resonance imaging in schizophrenia
    Til Wykes
    Department of Psychiatry, Institute of Psychiatry, London, UK
    Br J Psychiatry 181:144-52. 2002
    ..The results of one randomised control trial testing a psychological rehabilitation programme aimed at information processing strategies showed improvements in cognition post-treatment...
  2. ncbi request reprint More than just a place to talk: young people's experiences of group psychological therapy as an early intervention for auditory hallucinations
    Elizabeth Newton
    University College, London, UK
    Psychol Psychother 80:127-49. 2007
    ..The aim of the current study is to explore the experience of group-CBT amongst a group of young people experiencing distressing auditory hallucinations...
  3. ncbi request reprint Cognitive remediation therapy in schizophrenia: randomised controlled trial
    Til Wykes
    Department of Psychology, Kings College London, Institute of Psychiatry, London, UK
    Br J Psychiatry 190:421-7. 2007
    ..Cognitive difficulties are prevalent in people with a diagnosis of schizophrenia and are associated with poor long-term functioning...
  4. ncbi request reprint Cognitive remediation therapy (CRT) for young early onset patients with schizophrenia: an exploratory randomized controlled trial
    Til Wykes
    Institute of Psychiatry, Kings College London, De Crespigny Park, London, SE5 8AF, UK
    Schizophr Res 94:221-30. 2007
    ..The objective of this study is to evaluate the efficacy of CRT in alleviating cognitive deficits compared to treatment as usual and explore the mediating and moderating effects of cognitive improvement...
  5. doi request reprint Cognitive remediation for schizophrenia: it is even more complicated
    Til Wykes
    Department of Psychology, Institute of Psychiatry, King s College London, London, UK
    Curr Opin Psychiatry 22:161-7. 2009
    ..This review summarizes findings of induced cognitive change in schizophrenia, with reference to the remediation method, the presence of accompanying treatment(s), how cognitive change generalizes and its value...
  6. pmc Cognitive behavior therapy for schizophrenia: effect sizes, clinical models, and methodological rigor
    Til Wykes
    Department of Psychology, Institute of Psychiatry, King s College London, London, UK
    Schizophr Bull 34:523-37. 2008
    ..But recent advances have widened the CBTp targets to other symptoms and have different methods of provision, eg, in groups...
  7. ncbi request reprint Are the effects of cognitive remediation therapy (CRT) durable? Results from an exploratory trial in schizophrenia
    Til Wykes
    Department of Psychology, Institute of Psychiatry, De Crespigny Park, SE5 8AF, London, UK
    Schizophr Res 61:163-74. 2003
    ..At the end of treatment, CRT conferred a benefit to people with schizophrenia in cognition and self-esteem [Schizophr. Bull. 25 (1999) 291]. This study investigates these outcomes 6 months after the therapies were withdrawn...
  8. ncbi request reprint What are the effects of group cognitive behaviour therapy for voices? A randomised control trial
    Til Wykes
    Department of Psychology, Institute of Psychiatry, Kings College London, United Kingdom
    Schizophr Res 77:201-10. 2005
    ..This study tested whether a group based on cognitive behavioural principles could produce beneficial effects on hallucinations...
  9. ncbi request reprint Is it time to develop a new cognitive therapy for psychosis--cognitive remediation therapy (CRT)?
    T Wykes
    Kings College London, UK
    Clin Psychol Rev 21:1227-56. 2001
    ..The current review tries to put this evidence into context and sets out a programme of research, which is essential in this area if future progress is to be made...
  10. ncbi request reprint The prevalence and stability of an executive processing deficit, response inhibition, in people with chronic schizophrenia
    T Wykes
    Department of Psychology, Institute of Psychiatry, De Crespigny Park, SE5 8AF, London, UK
    Schizophr Res 46:241-53. 2000
    ..The level of response inhibition difficulties (about one-third) was identical in the new sample of patients, which suggests that response inhibition is not dependent on clinical history...
  11. doi request reprint Continuity of care in mental health: understanding and measuring a complex phenomenon
    T Burns
    Department of Psychiatry, University of Oxford, Warneford Hospital, Oxford, UK
    Psychol Med 39:313-23. 2009
    ..We aimed to operationalize a multi-axial model of continuity of care and to use factor analysis to determine its validity for severe mental illness...
  12. ncbi request reprint Group treatment of auditory hallucinations. Exploratory study of effectiveness
    T Wykes
    Department of Psychology, Institute of Psychiatry, London
    Br J Psychiatry 175:180-5. 1999
    ..Cognitive-behavioural therapy has been shown to be effective in reducing psychotic symptoms, but few patients have access to these services. Group cognitive treatment may provide a less costly service with similar benefits...
  13. doi request reprint Can we harness computerised cognitive bias modification to treat anxiety in schizophrenia? A first step highlighting the role of mental imagery
    Craig Steel
    Department of Psychology, University of Reading, Early Gate, Reading RG66AL, UK
    Psychiatry Res 178:451-5. 2010
    ..We discuss the implications for harnessing computerised CBM therapy developments for co-morbid anxiety in schizophrenia...
  14. ncbi request reprint Effects of depressed mood on objective and subjective measures of attention
    Lydia Farrin
    Gulf War Illnesses Research Unit, Guy s, King s, and St Thomas School of Medicine, London, UK
    J Neuropsychiatry Clin Neurosci 15:98-104. 2003
    ..Nonclinical depressed subjects may respond "catastrophically" to errors, heightening the subjective sense of failure and contributing to the strong relationship between subjectively reported cognitive failures and depression...
  15. pmc Assessing your mood online: acceptability and use of Moodscope
    G Drake
    Institute of Psychiatry, King s College London, UK
    Psychol Med 43:1455-64. 2013
    ..After 3 months, focus groups and questionnaires assessed use and usability of the tool...
  16. doi request reprint Impaired verbal self-monitoring in individuals at high risk of psychosis
    L C Johns
    Department of Psychological Medicine, Institute of Psychiatry, King s College London, UK
    Psychol Med 40:1433-42. 2010
    ..We used a paradigm that engages verbal self-monitoring (VSM) to examine whether this process is impaired in people experiencing prodromal symptoms, who have a very high risk of developing psychosis...
  17. ncbi request reprint The use of outcome measures to evaluate the efficacy and tolerability of antipsychotic medication: a comparison of Thorn graduate and CPN practice
    R Gray
    Health Services Research Department, Institute of Psychiatry, De Crespigny Park, London, UK
    J Psychiatr Ment Health Nurs 8:191-6. 2001
    ..A programme of targeted training may be a more realistic and efficient method of enhancing medication management practices in large numbers of CPNs compared to the more expensive and time-consuming Thorn programme...
  18. doi request reprint Different components of metacognition and their relationship to psychotic-like experiences
    Clare Reeder
    Institute of Psychiatry, King s College London, UK
    Behav Cogn Psychother 38:49-57. 2010
    ..However, studies offering supporting evidence have failed to distinguish between metacognitive beliefs about the consequences of having certain thoughts, and metacognitive beliefs about one's own cognitive skills...
  19. doi request reprint The self or the voice? Relative contributions of self-esteem and voice appraisal in persistent auditory hallucinations
    Dominic Fannon
    Division of Psychological Medicine and Psychiatry, Institute of Psychiatry, Kings College London, Denmark Hill, London, UK
    Schizophr Res 112:174-80. 2009
    ..It was hypothesized that low self-esteem is prominent in, and contributes to, depression in voice hearers...
  20. pmc Cognitive predictors of social functioning improvements following cognitive remediation for schizophrenia
    Clare Reeder
    Department of Psychology, Institute of Psychiatry, Kings College, De Crespigny Park, London SE5 8AF, UK
    Schizophr Bull 32:S123-31. 2006
    ..Improvement in the ability to generate new schemas has a beneficial impact on social functioning...
  21. pmc Schizophrenia patients with cognitive deficits: factors associated with costs
    Anita Patel
    Centre for the Economics of Mental Health, Institute of Psychiatry, King s College London, De Crespigny Park, London, UK
    Schizophr Bull 32:776-85. 2006
    ..Further investigation in larger samples is needed to confirm this finding and to explore its generalizability to those with less severe deficits...
  22. ncbi request reprint Negative symptoms and specific cognitive impairments as combined targets for improved functional outcome within cognitive remediation therapy
    Kathryn E Greenwood
    Department of Psychology, Institute of Psychiatry, London
    Schizophr Bull 31:910-21. 2005
    ..Both cognitive processes and negative symptoms should be targeted in cognitive remediation to effect the greatest change in community functions...
  23. doi request reprint Does age matter? Effects of cognitive rehabilitation across the age span
    Til Wykes
    King s College, Institute of Psychiatry London, UK
    Schizophr Res 113:252-8. 2009
    ..Cognitive remediation (CR) therapy in its various disguises can be helpful for people with schizophrenia but it is not clear if patient characteristics are likely to interfere with its effectiveness...
  24. ncbi request reprint The effect of medication management training on community mental health nurse's clinical skills
    Richard Gray
    Health Services Research Department, Institute of Psychiatry, De Crespigny Park, SE5 8AF, London, UK
    Int J Nurs Stud 40:163-9. 2003
    ..Conclusions. In this uncontrolled study training improved the medication management skills of CMHNs...
  25. pmc Patients' perspectives on electroconvulsive therapy: systematic review
    Diana Rose
    Service User Research Enterprise, PO34, Institute of Psychiatry, De Crespigny Park, London SE5 8AF
    BMJ 326:1363. 2003
    ..To ascertain patients' views on the benefits of and possible memory loss from electroconvulsive therapy...
  26. doi request reprint A comparison of participant information elicited by service user and non-service user researchers
    Diana Rose
    Institute of Psychiatry, King s College London, De Crespigny Park, London SE5 8AF, United Kingdom
    Psychiatr Serv 62:210-3. 2011
    ..The study examined whether data collected by researchers who were service users differed from data collected by non-service user researchers in a study that measured perceived coercion...
  27. ncbi request reprint Which executive skills should we target to affect social functioning and symptom change? A study of a cognitive remediation therapy program
    Clare Reeder
    Department of Psychology, Institute of Psychiatry, London, UK
    Schizophr Bull 30:87-100. 2004
    ..Regardless of treatment type, increased response inhibition speed was associated with reduced negative symptoms. Stimulus-driven responding and response inhibition speed may therefore make useful targets for intervention...
  28. ncbi request reprint Effect of a medication management training package for nurses on clinical outcomes for patients with schizophrenia: cluster randomised controlled trial
    Richard Gray
    PO 30, Health Services Research Department, Institute of Psychiatry, De Crespigny Park, London SE5 8AF
    Br J Psychiatry 185:157-62. 2004
    ..Non-compliance attenuates the efficacy of treatments for physical and mental disorders...
  29. doi request reprint Cognitive remediation therapy in schizophrenia: cost-effectiveness analysis
    Anita Patel
    Centre for the Economics of Mental Health, Health Service and Population Research Department, Box 24, Institute of Psychiatry, King s College London, De Crespigny Park, London SE5 8AF, United Kingdom
    Schizophr Res 120:217-24. 2010
    ..There is a lack of evidence on the cost-effectiveness of cognitive remediation therapy (CRT)...
  30. doi request reprint Executive functioning in schizophrenia and the relationship with symptom profile and chronicity
    Kathryn E Greenwood
    Department of Psychology, Institute of Psychiatry, London, United Kingdom
    J Int Neuropsychol Soc 14:782-92. 2008
    ..The executive profile, therefore, is related to symptom type rather than chronicity...
  31. doi request reprint A model for developing outcome measures from the perspectives of mental health service users
    Diana Rose
    Service User Research Enterprise, Institute of Psychiatry, King s College London, UK
    Int Rev Psychiatry 23:41-6. 2011
    ..The final measure is subject to psychometric testing both to ensure it is robust and to explore similarities and differences with conventionally derived measures...
  32. doi request reprint Views of the Therapeutic Environment (VOTE): stakeholder involvement in measuring staff perceptions of acute in-patient care
    C Laker
    Department of Psychology, Institute of Psychiatry, Kings College London, United Kingdom
    Int J Nurs Stud 49:1403-10. 2012
    ..The impact of staff perceptions of daily work pressures on burnout requires further exploration because both issues may be adversely affecting the quality of staff interactions with service users...
  33. ncbi request reprint From compliance to concordance: a review of the literature on interventions to enhance compliance with antipsychotic medication
    R Gray
    MRC Fellow in Health Services Research, Health Services Research Department, Institute of Psychiatry, De Crespigny Park, London, UK
    J Psychiatr Ment Health Nurs 9:277-84. 2002
    ..However, interventions, such as compliance therapy, based on cognitive-behavioural techniques appear to be effective in enhancing compliance and preventing relapse...
  34. ncbi request reprint What are we changing with neurocognitive rehabilitation? Illustrations from two single cases of changes in neuropsychological performance and brain systems as measured by SPECT
    T Wykes
    Department of Pyschology, Institute of Psychiatry, London, UK
    Schizophr Res 34:77-86. 1998
    ..Further investigation of whether it is possible to change idiosyncratic strategy use is needed if we are to develop the efficacy of this remediation technique...
  35. ncbi request reprint Utilisation and costs of community mental health services. PRiSM Psychosis Study. 5
    P McCrone
    Section of Community Psychiatry PRiSM, Institute of Psychiatry, London
    Br J Psychiatry 173:391-8. 1998
    ..The costs and the effectiveness of mental health services need to be evaluated if provision is to be efficient. Service use and costs are described for two geographical areas in south London...
  36. pmc Metacognitive awareness of cognitive problems in schizophrenia: exploring the role of symptoms and self-esteem
    M Cella
    Institute of Psychiatry, King s College London, UK
    Psychol Med 44:469-76. 2014
    ..Symptom severity, and also self-esteem and social functioning, can have an impact on cognitive problem perception and help to explain the gap between objective and subjective cognitive assessments in psychosis...
  37. doi request reprint Developing a user-generated measure of continuity of care: brief report
    D Rose
    Institute of Psychiatry, King s College London, London, UK
    Acta Psychiatr Scand 119:320-4. 2009
    ..In contrast to others, this measure has been generated from the perspectives of service users. As continuity of care is a concern particularly for those with severe mental illness, we have confined our work to this population group...
  38. ncbi request reprint Early psychological intervention for auditory hallucinations: an exploratory study of young people's voices groups
    Elizabeth Newton
    Early Intervention Service and Department of Psychology, Mental Health Services, Wulstan Unit, Newtown Hospital, Newtown Road, Worcester WR5 1JG, UK
    J Nerv Ment Dis 193:58-61. 2005
    ..Significant reductions in auditory hallucinations occurred over the total treatment phase, but not over the waiting period. Further investigations in the form of randomized controlled trials are warranted...
  39. pmc Assessment of community functioning in people with schizophrenia and other severe mental illnesses: a white paper based on an NIMH-sponsored workshop
    Alan S Bellack
    University of Maryland School of Medicine, 737 West Lombard Street, Suite 551, Baltimore, MD 21201, USA
    Schizophr Bull 33:805-22. 2007
    ..This criterion is problematic because different observers and constituencies often have different opinions about what types of change are clinically important and how much change is significant...
  40. ncbi request reprint Modification of performance on the Span of Apprehension Task in a group of young people with early onset psychosis
    Torill Ueland
    Sogn Centre for Child and Adolescent Psychiatry, Oslo, Norway
    Scand J Psychol 45:55-60. 2004
    ..The study suggests that SPAN performance can be improved in young people with early onset psychosis using relatively simple interventions and that performance gains are relatively durable...
  41. ncbi request reprint Are all psychological treatments for psychosis equal? The need for CBT in the treatment of psychosis and not for psychodynamic psychotherapy
    Nicholas Tarrier
    Academic Division of Clinical Psychology, School of Psychiatry and Behavioural Science, University of Manchester, Wythenshawe Hospital, UK
    Psychol Psychother 75:365-74; discussion 375-9. 2002
    ..We consider the research and clinical priorities to be the further developments of CBT and family intervention methods, which could have significant benefits for sufferers of schizophrenia and their carers...
  42. pmc Identifying cognitive mechanisms targeted for treatment development in schizophrenia: an overview of the first meeting of the Cognitive Neuroscience Treatment Research to Improve Cognition in Schizophrenia Initiative
    Cameron S Carter
    Department of Psychiatry, University of California, Davis, CA 95817, USA
    Biol Psychiatry 64:4-10. 2008
    ..The articles in this special section report on the results of the first conference, which used a criterion-based consensus-building process to develop a set of cognitive constructs to be targeted for translation efforts...
  43. doi request reprint Neuropsychological task performance before and after cognitive remediation in anorexia nervosa: a pilot case-series
    Kate Tchanturia
    Psychol Med 38:1371-3. 2008
  44. ncbi request reprint Is there evidence that cognitive behaviour therapy is an effective treatment for schizophrenia? A cautious or cautionary tale?
    Nicholas Tarrier
    Academic Division of Clinical Psychology University of Manchester, Education and Research Building 2nd Floor, Wythenshawe Hospital, Manchester M23 9LT, UK
    Behav Res Ther 42:1377-401. 2004
    ..We conclude cautiously that overall there is good evidence for the efficacy and effectiveness of CBTp in the treatment of schizophrenia...
  45. doi request reprint Cognitive remediation and vocational rehabilitation
    Susan R McGurk
    Dartmouth Psychiatric Research Center, Dartmouth Medical School, Concord, NH 03301, USA
    Psychiatr Rehabil J 31:350-9. 2008
    ....