Research Topics
| Kim WolffSummaryAffiliation: King's College London Country: UK Publications
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Detail Information
Publications
A review of biological indicators of illicit drug use, practical considerations and clinical usefulnessK Wolff
National Addiction Centre, Institute of Psychiatry, Kings College London, UK
Addiction 94:1279-98. 1999..To examine a range of biological indicators of illicit drug use, including blood, urine, hair and saliva, addressing both technological and practical issues relating to their application and interpretation...
Vasopressin and oxytocin secretion in response to the consumption of ecstasy in a clubbing populationKim Wolff
National Addiction Centre, Institute of Psychiatry, King s College London, 4 Windsor Walk, London SE5 8AF, UK
J Psychopharmacol 20:400-10. 2006..This report demonstrates SIADH in ecstasy-using "clubbers", which has important clinical implications...
Ketamine : from medicine to misuseKim Wolff
King s College London National Addiction Centre, Institute of Psychiatry, London, England
CNS Drugs 20:199-218. 2006..The potential of ketamine as a novel clinical and research tool is matched by its abuse potential outside medical settings...
Changes to methadone clearance during pregnancyKim Wolff
National Addiction Centre, Division of Psychological Medicine, Institute of Psychiatry, King s College London, Addiction Sciences Building, 4, Windsor Walk, London, SE5 8AF, UK
Eur J Clin Pharmacol 61:763-8. 2005..A secondary objective was to evaluate the outcome of pregnancy...
Ecstasy (MDMA)-induced hyponatraemia is associated with genetic variants in CYP2D6 and COMTKatherine J Aitchison
MRC Social Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, London, UK
J Psychopharmacol 26:408-18. 2012....
Drug testing by chemical analysis of fingerprint deposits from methadone-maintained opioid dependent patients using UPLC-MS/MSShana Jacob
Pharmaceutical Sciences Research Division, King s College London, London SE1 9NH, UK
Drug Metab Lett 2:245-7. 2008..Chemical analysis of fingerprint deposits from methadone-maintained opioid-dependent patients by UPLC-MS/MS show detectable levels of methadone and its metabolite, EDDP, demonstrating intake of the drug...
Patterns of adherence to oral methadone: implications for prescribersMichael Haskew
South Camden Drug Service, Camden and Islington Mental Health and Social Care NHS Trust, London, UK
J Subst Abuse Treat 35:109-15. 2008..New approaches to encouraging adherence, including a more systematic monitoring of adherence to improve the effectiveness of methadone programs, are needed...
Follow-up of provision of inpatient treatment for UK Healthcare Professionals with alcohol dependence: snapshot of a pilot specialist National Health ServiceSamantha R Gross
National Addiction Centre, Institute of Psychiatry, Kings College, London, UK
Subst Use Misuse 44:1916-25. 2009..There is a need for supported and dedicated services for this group within the UK National Health Service. The study's limitations are noted...
Clozapine pharmacokinetics and pharmacodynamics studied with Cyp1A2-null miceK J Aitchison
Section of Clinical Pharmacology, Institute of Psychiatry, London, UK
J Psychopharmacol 14:353-9. 2000..Our data also indicate that CYP1A2 poor metabolizers might be more susceptible than extensive metabolizers to dose-related adverse effects of clozapine, such as sedation, myoclonus and seizures...
Pharmacogenetic studies of change in cortisol on ecstasy (MDMA) consumptionKim Wolff
King s College London, Institute of Psychiatry, Addiction Department, London, UK
J Psychopharmacol 26:419-28. 2012....
Hydrophilic stationary phases: a practical approach for the co-analysis of compounds with varying polarity in biological matricesEdward Goucher
Department of Forensic Science and Drug Monitoring, Pharmaceutical Science Research Division, King s College London, London, UK
J Sep Sci 33:955-65. 2010..LC-MS/MS analysis of creatinine and drug compounds together offers considerable advantages over traditional approaches that necessitate the quantification of creatinine using spectrophotometric approaches...
4-MTA: a new synthetic drug on the dance sceneAdam R Winstock
National Addiction Centre, Institute of Psychiatry, Addiction Sciences Building, 4 Windsor Walk, SE5 8AF, London, UK
Drug Alcohol Depend 67:111-5. 2002..Responses to the effects of the drug were mixed, although about a quarter of those who believed that they had tried 4-MTA thought that they would use it again...
Characterization of methadone overdose: clinical considerations and the scientific evidenceKim Wolff
National Addiction Centre, London, United Kingdom
Ther Drug Monit 24:457-70. 2002..Indeed the key issue with methadone that sets it apart from other opioids is its potential for delayed toxicity. Consequently steps should be taken to disseminate the salient facts to all those who come into contact with the drug...
Ecstasy pill testing: harm minimization gone too far?A R Winstock
National Addiction Centre, Institute of Psychiatry, Kings College London, UK
Addiction 96:1139-48. 2001..At best it gives an artificial 'shine of safety' to a group of diverse drugs that remain both illicit and potentially harmful. Other simpler harm reduction mechanisms are likely to be more effective...
Excessive alcohol consumption is associated with reduced quality of life among methadone patientsRichard Senbanjo
East Kent Community Drug Service, KCA, Ashford, Kent, UK
Addiction 102:257-63. 2007..To evaluate the impact of excessive alcohol consumption on the health-related quality of life of patients receiving methadone treatment for opioid dependence...
Using focus group interviews to understand staff perceptions from training in the therapeutic community modelAnna Tsiboukli
Hellenic Open University, Athens, Greece
J Drug Educ 33:143-57. 2003..The article concludes that gaining information on people's own perceptions and experiences from the training process can contribute significantly to program improvement...
