S Warnakulasuriya

Summary

Affiliation: King's College London
Country: UK

Publications

  1. doi request reprint Factors predicting malignant transformation in oral potentially malignant disorders among patients accrued over a 10-year period in South East England
    S Warnakulasuriya
    Department of Clinical and Diagnostic Sciences, Oral Medicine, King s College London Dental Institute and the WHO Collaborating Centre for Oral Cancer and Precancer, London, UK
    J Oral Pathol Med 40:677-83. 2011
  2. pmc Malignant transformation of oral potentially malignant disorders in males: a retrospective cohort study
    Pei Shan Ho
    Division of Oral and Maxillofacial Surgery, Department of Dentistry, Kaoshiung Medical University Hospital, Kaohsiung, Taiwan, Republic of China
    BMC Cancer 9:260. 2009
  3. ncbi request reprint Multiple primary tumours following head and neck cancer in southern England during 1961-98
    K A A S Warnakulasuriya
    Department of Oral Medicine and Pathology, Guy s, King s and St Thomas Dental Institute and WHO Collaborating Centre for Oral Cancer and Precancer, Demark Hill Campus, Caldecot Road, London SE5 9RW, UK
    J Oral Pathol Med 32:443-9. 2003
  4. ncbi request reprint Nomenclature and classification of potentially malignant disorders of the oral mucosa
    S Warnakulasuriya
    Department of Oral Medicine, King s College London Dental Institute at Guy s, Denmark Hill Campus, Caldecot Road, London, UK
    J Oral Pathol Med 36:575-80. 2007
  5. doi request reprint Is workplace screening for potentially malignant oral disorders feasible in India?
    S Warnakulasuriya
    Department of Oral Medicine, King s College London, London, UK
    J Oral Pathol Med 39:672-6. 2010
  6. ncbi request reprint Oral health risks of tobacco use and effects of cessation
    Saman Warnakulasuriya
    King s College London and WHO Collaborating Centre for Oral Cancer and Precancer, UK
    Int Dent J 60:7-30. 2010
  7. doi request reprint Causes of oral cancer--an appraisal of controversies
    S Warnakulasuriya
    Department of Oral Medicine WHO Collaborating Centre for Oral Cancer and Precancer, King s College London Dental Institute, Denmark Hill Campus, Bessemer Road, London
    Br Dent J 207:471-5. 2009
  8. ncbi request reprint Tobacco, oral cancer, and treatment of dependence
    Saman Warnakulasuriya
    Department of Oral Medicine and Pathology, Guy s, King s and St Thomas School of Dentistry, WHO Collaborating Centre for Oral Cancer and Precancer, King s College London, Denmark Hill Campus, Caldecot Road, London SE5 9RW, UK
    Oral Oncol 41:244-60. 2005
  9. doi request reprint Global epidemiology of oral and oropharyngeal cancer
    Saman Warnakulasuriya
    Department of Oral Medicine and Experimental Oral Pathology, King s College Dental Institute, Bessemer Road, London SE5 9RS, UK
    Oral Oncol 45:309-16. 2009
  10. ncbi request reprint Oral cancer survival in young people in South East England
    Saman Warnakulasuriya
    Department of Oral Medicine, King s College Dental Institute at Guy s, King s and St Thomas Hospitals, WHO Collaborating Centre for Oral Cancer and Precancer, Denmark Hill Campus, Caldecot Road, London SE5 9RW, UK
    Oral Oncol 43:982-6. 2007

Collaborators

Detail Information

Publications45

  1. doi request reprint Factors predicting malignant transformation in oral potentially malignant disorders among patients accrued over a 10-year period in South East England
    S Warnakulasuriya
    Department of Clinical and Diagnostic Sciences, Oral Medicine, King s College London Dental Institute and the WHO Collaborating Centre for Oral Cancer and Precancer, London, UK
    J Oral Pathol Med 40:677-83. 2011
    ..The aims of the study were to determine how frequently oral potentially malignant disorders (OPMDs) transform to cancer and to identify clinical and histological factors determining the rates of transformation...
  2. pmc Malignant transformation of oral potentially malignant disorders in males: a retrospective cohort study
    Pei Shan Ho
    Division of Oral and Maxillofacial Surgery, Department of Dentistry, Kaoshiung Medical University Hospital, Kaohsiung, Taiwan, Republic of China
    BMC Cancer 9:260. 2009
    ..The aim of our study was to estimate the rate of malignant transformation of OPMDs taking into account the duration of follow-up and to identify the significant factors indicative of malignant potential...
  3. ncbi request reprint Multiple primary tumours following head and neck cancer in southern England during 1961-98
    K A A S Warnakulasuriya
    Department of Oral Medicine and Pathology, Guy s, King s and St Thomas Dental Institute and WHO Collaborating Centre for Oral Cancer and Precancer, Demark Hill Campus, Caldecot Road, London SE5 9RW, UK
    J Oral Pathol Med 32:443-9. 2003
    ..Successful initial treatment of oral and oro-phayngeal cancer has led to the emergence of second primary tumours (SPTs). Population data are meagre...
  4. ncbi request reprint Nomenclature and classification of potentially malignant disorders of the oral mucosa
    S Warnakulasuriya
    Department of Oral Medicine, King s College London Dental Institute at Guy s, Denmark Hill Campus, Caldecot Road, London, UK
    J Oral Pathol Med 36:575-80. 2007
    ..The terminology presented in this report reflects our best understanding of multi-step carcinogenesis in the oral mucosa, and aspires to engender consistency in use...
  5. doi request reprint Is workplace screening for potentially malignant oral disorders feasible in India?
    S Warnakulasuriya
    Department of Oral Medicine, King s College London, London, UK
    J Oral Pathol Med 39:672-6. 2010
    ..However, those who work during the day may not visit screening centers or be at home during the day of the screening by a visiting health care worker. Workplace screening overcomes these challenges...
  6. ncbi request reprint Oral health risks of tobacco use and effects of cessation
    Saman Warnakulasuriya
    King s College London and WHO Collaborating Centre for Oral Cancer and Precancer, UK
    Int Dent J 60:7-30. 2010
    ..Substantial oral health benefits can be expected from abstention and successful smoking cessation in a variety of populations across all ages...
  7. doi request reprint Causes of oral cancer--an appraisal of controversies
    S Warnakulasuriya
    Department of Oral Medicine WHO Collaborating Centre for Oral Cancer and Precancer, King s College London Dental Institute, Denmark Hill Campus, Bessemer Road, London
    Br Dent J 207:471-5. 2009
    ..Some controversies related to the aetiology of this disease also need clarification. The objective of this paper is to provide an opinion on these debated controversies...
  8. ncbi request reprint Tobacco, oral cancer, and treatment of dependence
    Saman Warnakulasuriya
    Department of Oral Medicine and Pathology, Guy s, King s and St Thomas School of Dentistry, WHO Collaborating Centre for Oral Cancer and Precancer, King s College London, Denmark Hill Campus, Caldecot Road, London SE5 9RW, UK
    Oral Oncol 41:244-60. 2005
    ..This review makes recommendations for interventions by health professionals to encourage and aid cessation of tobacco use as a part of prevention of oral cancer...
  9. doi request reprint Global epidemiology of oral and oropharyngeal cancer
    Saman Warnakulasuriya
    Department of Oral Medicine and Experimental Oral Pathology, King s College Dental Institute, Bessemer Road, London SE5 9RS, UK
    Oral Oncol 45:309-16. 2009
    ....
  10. ncbi request reprint Oral cancer survival in young people in South East England
    Saman Warnakulasuriya
    Department of Oral Medicine, King s College Dental Institute at Guy s, King s and St Thomas Hospitals, WHO Collaborating Centre for Oral Cancer and Precancer, Denmark Hill Campus, Caldecot Road, London SE5 9RW, UK
    Oral Oncol 43:982-6. 2007
    ..For the young age group (0-44 years) mean relative survival for the period under study was relatively constant but consistently higher in younger women than in younger men...
  11. doi request reprint Oral epithelial dysplasia classification systems: predictive value, utility, weaknesses and scope for improvement
    S Warnakulasuriya
    Department of Oral Medicine, King s College Dental Institute at Guy s, King s and St Thomas Hospitals, London, UK
    J Oral Pathol Med 37:127-33. 2008
    ....
  12. ncbi request reprint Effectiveness of tobacco counseling in the dental office
    Saman Warnakulasuriya
    Department of Oral Medicine and Experimental Pathology, WHO Collaborating Centre for Oral Cancer and Precancer, Guy s, King s and St Thomas School of Dentistry, King s College London, UK
    J Dent Educ 66:1079-87. 2002
    ..The challenge is implementing effective treatment in one's practice or institution while using available primary care resources to provide additional benefit...
  13. ncbi request reprint Fluoride content of alcoholic beverages
    Saman Warnakulasuriya
    Department of Oral Medicine and Pathology, Guy s, King s and St Thomas Schools of Medicine and Dentistry, Denmark Hill Campus, King s College London, Caldecot Road, London SE5 9RW, UK
    Clin Chim Acta 320:1-4. 2002
    ..In view of the conflicting reports of the extent and severity of dental caries in alcohol misusing subjects, a systematic survey of the fluoride content of alcoholic beverages was undertaken...
  14. doi request reprint Living with oral cancer: epidemiology with particular reference to prevalence and life-style changes that influence survival
    Saman Warnakulasuriya
    Department of Oral Medicine and Pathology, King s College Dental Institute, Bessemer Rd, London SE5 9RS, UK
    Oral Oncol 46:407-10. 2010
    ..Smoking cessation in particular improves prognostic outcomes reducing the risk of secondary disease by approximately 2-3-fold...
  15. ncbi request reprint Clinical, pathological, cellular and molecular lesions caused by oral smokeless tobacco--a review
    K A A S Warnakulasuriya
    Department of Oral Medicine and Pathology, WHO Collaborating Centre for Oral Cancer and Precancer, King s College Dental Institute at Guy s, King s and St Thomas Hospitals, London, UK
    J Oral Pathol Med 36:63-77. 2007
    ..Genetic aberrations caused by ST include activation of ras, uncommon in smokers but mutational hot spots in p53 encountered are similar to those in smokers...
  16. ncbi request reprint Histological grading of oral epithelial dysplasia: revisited
    S Warnakulasuriya
    Department of Oral Medicine and Pathology, WHO Collaborating Centre for Oral Cancer and Precancer, Guy s, King s and St Thomas School of Medicine and Dentistry, King s College London, Denmark Hill Campus, Caldecot Road, London, UK
    J Pathol 194:294-7. 2001
    ..They are potential biomarker candidates but their utility in prognosis of oral precancer deserves further study...
  17. ncbi request reprint Cancer of mouth, pharynx and nasopharynx in Asian and Chinese immigrants resident in Thames regions
    K A Warnakulasuriya
    Department of Oral Medicine and Pathology, Guy s, King s and St Thomas School of Dentistry, London, UK
    Oral Oncol 35:471-5. 1999
    ..The south Asian and Chinese ethnic minorities constitute important high risk groups for oral and nasopharyngeal cancer, for whom targeted prevention is indicated...
  18. doi request reprint Utility of chemiluminescence (ViziLite™) in the detection of oral potentially malignant disorders and benign keratoses
    K H Awan
    Oral Medicine, King s College London Dental Institute, London, UK
    J Oral Pathol Med 40:541-4. 2011
    ..Data derived were compared in relation to conventional oral examination and surgical biopsy...
  19. doi request reprint Utility of toluidine blue as a diagnostic adjunct in the detection of potentially malignant disorders of the oral cavity--a clinical and histological assessment
    Kh Awan
    Oral Medicine and Head and Neck Pathology, Department of Clinical and Diagnostic Sciences, King s College London Dental Institute, London, UK
    Oral Dis 18:728-33. 2012
    ..The value of chairside adjunctive tests in the detection of oral potentially malignant disorders (OPMDs) remains uncertain...
  20. ncbi request reprint Areca nut use following migration and its consequences
    S Warnakulasuriya
    Department of Oral Medicine and Pathology, Guy s School of Dentistry, WHO Collaborating Centre for Oral Cancer and Precancer, King s College London, Denmark Hill Campus, London, UK
    Addict Biol 7:127-32. 2002
    ..The two products are psychologically addictive and a dependency syndrome related to their use among Asian immigrants to the United Kingdom has been described recently...
  21. ncbi request reprint The oral health consequences of chewing areca nut
    C R Trivedy
    Department of Oral Pathology and Medicine, WHO Collaborating Center for Oral Cancer and Precancer, The Guy s Medical and Dental School of King s College, London, UK
    Addict Biol 7:115-25. 2002
    ..Public health measures to quit areca use are recommended to control disabling conditions such as submucous fibrosis and oral cancer among Asian populations...
  22. doi request reprint Evaluation of an autofluorescence based imaging system (VELscope™) in the detection of oral potentially malignant disorders and benign keratoses
    K H Awan
    Oral Medicine, Department of Clinical and Diagnostic Sciences, King s College London Dental Institute, United Kingdom
    Oral Oncol 47:274-7. 2011
    ..1% and 15.3% respectively. While VELscope was useful in confirming the presence of oral leukoplakia and erythroplakia and other oral mucosal disorders, the device was unable to discriminate high-risk from low-risk lesions...
  23. ncbi request reprint The two-week wait cancer initiative on oral cancer; the predictive value of urgent referrals to an oral medicine unit
    P Singh
    Department of Oral Medicine and Pathology, WHO Collaborating Centre for Oral Cancer and Precancer, King s College London Dental Institute, Denmark Hill Campus, Caldecot Road, London, UK
    Br Dent J 201:717-20; discussion 714. 2006
    ..The two-week wait cancer initiative was designed to speed up referral of patients suspected of having cancer. The National Institute of Clinical Excellence (NICE) has issued guidelines for head and neck cancers warranting urgent referral...
  24. ncbi request reprint Effective management of smoking in an oral dysplasia clinic in London
    T W J Poate
    Department of Oral Medicine and Pathology, WHO Collaborating Centre for Oral Cancer and Precancer, Guy s, King s and St Thomas Dental Institute, King s College, London, UK
    Oral Dis 12:22-6. 2006
    ..The risk factors include tobacco and excess alcohol use and diets low in antioxidants. Studies concerning the management of risk factors related to oral precancer are meager...
  25. pmc Role of p16/MTS1, cyclin D1 and RB in primary oral cancer and oral cancer cell lines
    M Sartor
    Department of Oral Medicine and Pathology, The Rayne Institute, King s College School of Medicine and Dentistry, London, UK
    Br J Cancer 80:79-86. 1999
    ..The RB protein was expressed in about half (44%) of OSCCs and its expression inversely correlated with p16/MTS1 expression. In conclusion, we show that abnormalities of the RB pathway are a common mechanism of oral carcinogenesis...
  26. ncbi request reprint Effect of areca nut on salivary copper concentration in chronic chewers
    Kishor B Raja
    Department of Clinical Biochemistry, Guy s, King s and St Thomas School of Medicine, Denmark Hill Campus, London, SE5 9RS, UK
    Biometals 20:43-7. 2007
    ..These data indicate that soluble copper found in areca nut is released into the oral environment of habitual chewers. Its buccal absorption may contribute to the oral fibrosis in Asians who regularly chew this nut...
  27. ncbi request reprint The impact of stomatological disease on oral health-related quality of life
    Carrie Diane Llewellyn
    Department of Oral Medicine and Pathology, Guy s, King s and St Thomas Schools of Medicine and Dentistry, King s College Hospital, London, UK
    Eur J Oral Sci 111:297-304. 2003
    ..Patient centred, routine assessment of OHR-QoL provides an additional dimension that may help to improve awareness of the impact of disease on the individual's life and enhance the clinical decision-making process...
  28. ncbi request reprint Evaluation of tobacco use cessation (TUC) counselling in the dental office
    Ian Needleman
    International Centre for Evidence Based Oral Health, Unit of Periodontology, UCL Eastman Dental Institute, London, UK
    Oral Health Prev Dent 4:27-47. 2006
    ..Therefore both self-reported and biochemical measures of tobacco use should be reported in evaluation studies. It is also clear that feedback from biochemical testing of tobacco use can increase success rates in tobacco use cessation...
  29. doi request reprint Demonstration of ethanol-induced protein adducts in oral leukoplakia (pre-cancer) and cancer
    Saman Warnakulasuriya
    Department of Oral Medicine, King s College London Dental Institute at Guy s, King s and St Thomas Hospitals, WHO Collaborating Centre for Oral Cancer and Precancer, London, UK
    J Oral Pathol Med 37:157-65. 2008
    ..Excessive alcohol consumption is a common cause for upper gastrointestinal tract cancers. However, the primary mechanisms of alcohol-induced carcinogenesis have remained poorly defined...
  30. ncbi request reprint Oral submucous fibrosis: review on aetiology and pathogenesis
    W M Tilakaratne
    The Centre for Research in Clinical and Diagnostic Oral Sciences, School of Medicine and Dentistry, Barts and The London, London, UK
    Oral Oncol 42:561-8. 2006
    ..The individual mechanisms operating at various stages of the disease-initial, intermediate and advanced-need further study in order to propose appropriate therapeutic interventions...
  31. ncbi request reprint Factors associated with delay in presentation among younger patients with oral cancer
    Carrie D Llewellyn
    Department of Oral Medicine and Pathology, WHO Collaborating Centre for Oral Cancer and Precancer, Guy s, King s, and St Thomas Schools of Medicine and Dentistry, King s College London, UK
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 97:707-13. 2004
    ..This has important implications for increasing sign and symptom awareness among the public and primary health care professionals such as general medical practitioners and general dentists...
  32. ncbi request reprint An analysis of risk factors for oral cancer in young people: a case-control study
    Carrie D Llewellyn
    Department of Oral Medicine and Pathology, WHO Collaborating Centre for Oral Cancer and Precancer, Guy s, King s and St Thomas School of Dentistry, King s College London, Denmark Hill Campus, Caldecot Road, London SE5 9RW, UK
    Oral Oncol 40:304-13. 2004
    ....
  33. ncbi request reprint Chemical and analytical aspects of areca nut
    G A Lord
    MRC Bioanalytical Science Group, School of Biological and Chemical Sciences, Birkbeck, University of London, London, UK
    Addict Biol 7:99-102. 2002
    ..6) as the running buffer at a voltage of 20 kV and temperature of 30 degrees C. The method is applicable to the analysis of alkaloids in the nut, commercial preparations (pan masala) and in the saliva of areca nut chewers...
  34. doi request reprint Angioleiomyoma: an unusual diagnosis for a lump in the cheek
    Helen McParland
    Department Oral Medicine, King s College London Dental Institute, London, United Kingdom
    Br J Oral Maxillofac Surg 47:641-2. 2009
    ..Deep dissection to excise the mass completely caused no damage to nerves and there has been no recurrence...
  35. ncbi request reprint Aplasia of submandibular salivary glands associated with ectodermal dysplasia
    Parmjit Singh
    Department of Oral Medicine, Guy s, King s and St Thomas Dental Institute, Denmark Hill Campus, London, UK
    J Oral Pathol Med 33:634-6. 2004
    ..The case highlights that hypoplasia and aplasia of exocrine glands could be rare features of ED. In the management of ED, early detection of xerostomia is important to limit any potential damage to the already hypodontic dentition...
  36. ncbi request reprint Oral precancerous disorders associated with areca quid chewing, smoking, and alcohol drinking in southern Taiwan
    Ching Hung Chung
    Graduate Institutes of Dental Sciences, Oral Health Sciences and Oral Health Research Center, Kaohsiung Medical University, Kaohsiung, Taiwan
    J Oral Pathol Med 34:460-6. 2005
    ..To investigate the prevalence and the associated risk factors of oral precancerous disorders in southern Taiwan...
  37. pmc Areca nut use: an independent risk factor for oral cancer
    Saman Warnakulasuriya
    BMJ 324:799-800. 2002
  38. ncbi request reprint Incidence rates for oral leukoplakia and lichen planus in a Japanese population
    Toru Nagao
    Department of Oral and Maxillofacial Surgery II, School of Dentistry, Aichi Gakuin University, Nagoya, Japan
    J Oral Pathol Med 34:532-9. 2005
    ..This is the first study to report on the age-specific incidence of oral leukoplakia and oral lichen planus from an industrialized country...
  39. ncbi request reprint The role of the dental team in preventing and diagnosing cancer: 4. Risk factor reduction: tobacco cessation
    Crispian Scully
    Eastman Dental Institute for Oral Health Care Sciences, 256 Gray s Inn Road, University College London, London WC1 X 8LD
    Dent Update 32:394-6, 399-401. 2005
    ....
  40. ncbi request reprint Oral pre-cancer and the associated risk factors among industrial workers in Japan's overseas enterprises in the UK
    Toru Nagao
    Second Department of Oral and Maxillofacial Surgery, School of Dentistry, Aichi Gakuin University, Japan
    J Oral Pathol Med 32:257-64. 2003
    ..This study describes the prevalence of oral pre-cancerous lesions and other mucosal diseases following oral mucosal screening, and associated risk factors among Japanese industrial workers in the UK...
  41. ncbi request reprint Annual screening for oral cancer detection
    Toru Nagao
    Second Department of Oral and Maxillofacial Surgery, School of Dentistry, Aichi Gakuin University, 2 11 Suemori dori, Chikusa ku, 464 8651, Nagoya, Japan
    Cancer Detect Prev 27:333-7. 2003
    ....
  42. ncbi request reprint Gene expression profile of oral squamous cell carcinomas from Sri Lankan betel quid users
    Mai Lill Suhr
    Department of Biomedicine, University of Bergen, Jonas Lies Vej 91, 5009 Bergen, Norway
    Oncol Rep 18:1061-75. 2007
    ..These findings provide valuable information that might help in the selection of possible biomarkers that can be used in early detection of the alarming problem of oral cancer in Southeast Asia...
  43. ncbi request reprint Oral lichen planus and oral lichenoid lesions: diagnostic and therapeutic considerations
    Ibtisam Al-Hashimi
    Salivary Dysfunction Clinic, Baylor College of Dentistry, Houston, TX, USA
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 103:S25.e1-12. 2007
    ..Oral lichenoid lesions of graft-versus-host disease (OLL-GVHD) are recognized to have an association with malignancy. Local therapy for these lesions rests in topical agents, predominantly corticosteroids...
  44. ncbi request reprint Management of oral epithelial dysplasia: a review
    Michael Brennan
    Carolinas Medical Center, Charlotte, NC, USA
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 103:S19.e1-12. 2007
    ..Because of the lack of randomized controlled trials that have shown effectiveness in the prevention of malignant transformation, no recommendations can be provided for specific surgical interventions of dysplastic oral lesions either...
  45. pmc Areca (betel) nut chewing habit among high-school children in the Commonwealth of the Northern Mariana Islands (Micronesia)
    Eric Oakley
    Saipan Seventh Day Adventist Clinic, Saipan
    Bull World Health Organ 83:656-60. 2005
    ..Information on usage by young people, however, is scarce...