Research Topics
| Francisco M VegaSummaryAffiliation: King's College London Country: UK Publications
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Detail Information
Publications
Rho GTPases in cancer cell biologyFrancisco M Vega
Randall Division of Cell and Molecular Biophysics, King s College London, New Hunt s House, Guy s Campus, London SE1 1UL, UK
FEBS Lett 582:2093-101. 2008..Here, we discuss how Rho GTPases could contribute to different steps of cancer progression, including proliferation, survival, invasion and metastasis...
Cdc42 promotes transendothelial migration of cancer cells through β1 integrinNicolas Reymond
Randall Division of Cell and Molecular Biophysics, King s College London, London SE1 1UL, England, UK
J Cell Biol 199:653-68. 2012..By identifying β1 integrin as a transcriptional target of Cdc42, our results provide new insight into Cdc42 function...
SnapShot: Rho family GTPasesFrancisco M Vega
Randall Division of Cell and Molecular Biophysics, King's College London, London, UK
Cell 129:1430. 2007
RhoA and RhoC have distinct roles in migration and invasion by acting through different targetsFrancisco M Vega
Randall Division of Cell and Molecular Biophysics, King s College London, London SE1 1UL, England, UK
J Cell Biol 193:655-65. 2011..We propose that RhoA contributes to migratory cell polarity through ROCK2-mediated suppression of Rac1 activity in lamellipodia, whereas RhoC promotes polarized migration through FMNL3 by restricting lamellipodial broadening...
RhoB regulates cell migration through altered focal adhesion dynamicsFrancisco M Vega
Randall Division of Cell and Molecular Biophysics, King s College London, New Hunt s House, Guy s Campus, London SE1 1UL, UK
Open Biol 2:120076. 2012..We propose that RhoB contributes to directional cell migration by regulating β1 integrin surface levels and activity, thereby stabilizing lamellipodial protrusions...
