Research Topics
Genomes and GenesSpecies | Abigail TuckerSummaryAffiliation: King's College London Country: UK Publications
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Detail Information
Publications
The cutting-edge of mammalian development; how the embryo makes teethAbigail Tucker
Department of Craniofacial Development, Dental Institute, Kings College London, Floor 28 Guys Hospital, London Bridge, London SE1 9RT, UK
Nat Rev Genet 5:499-508. 2004
Incudomalleal joint formation: the roles of apoptosis, migration and downregulationSusan Amin
Department of Craniofacial Development and Orthodontics, King s College London, London, UK
BMC Dev Biol 7:134. 2007..Understanding how this joint forms during normal development is thus an important step in furthering our understanding of such defects...
Salivary gland adaptations: modification of the glands for novel usesAbigail S Tucker
Department of Craniofacial Development and Orthodontics, Guy s Hospital, London, UK
Front Oral Biol 14:21-31. 2010..In this chapter these different adaptations will be discussed, looking at how the salivary glands have become adapted to their new role, with insights from developmental biology and evolution...
Salivary gland developmentA S Tucker
Department of Craniofacial Development and Orthodontics, King s College London, Floor 27 Guy s Tower, London Bridge, SE1 9RT London, UK
Semin Cell Dev Biol 18:237-44. 2007..Finally, the genes thought to play a role in development of the glands from initiation to differentiation will be reviewed...
Neural crest cells provide species-specific patterning information in the developing branchial skeletonAbigail S Tucker
MRC Centre for Developmental Neurobiology, King s College London, Guy s Hospital, London, SE1 1UL, UK
Evol Dev 6:32-40. 2004..The ability to form species-specific patterns of craniofacial skeletal tissue thus appears to be an inherent property of the neural crest, expressed as species-specific responses to endodermal signals...
Independent induction and formation of the dorsal and ventral fins in Xenopus laevisA S Tucker
Departments of Craniofacial Development and Orthodontics, King s College London, Guy s Tower, Guy s Hospital, London Bridge, London, United Kingdom
Dev Dyn 230:461-7. 2004..The ventral fin contains neural crest cells that migrate in from the dorsal side of the embryo, but a contribution is also made by cells from the ventral mesoderm...
A regulatory relationship between Tbx1 and FGF signaling during tooth morphogenesis and ameloblast lineage determinationThimios A Mitsiadis
Department of Orofacial Development and Structure, Institute of Oral Biology, ZZMK, Faculty of Medicine, University of Zurich, Plattenstrasse 11, CH 8032 Zurich, Switzerland
Dev Biol 320:39-48. 2008..Forced expression of Tbx1 in dental explants activates amelogenin expression. These results indicate that Tbx1 expression in developing teeth is under control of FGF signaling and correlates with determination of the ameloblast lineage...
The role of transforming growth factor-beta signalling in the patterning of the proximal processes of the murine dentaryNeal Anthwal
Department of Craniofacial Development, Kings College London, London, United Kingdom
Dev Dyn 237:1604-13. 2008..This study suggests that the proper development of the processes and their secondary cartilages relies on both Tgf-beta signalling and mechanical forces working in concert...
Sonic hedgehog in the pharyngeal endoderm controls arch pattern via regulation of Fgf8 in head ectodermKim E Haworth
Department of Craniofacial Development, Dental Institute, Kings College London, London SE1 9RT, UK
Dev Biol 303:244-58. 2007..Shh from the pharyngeal endoderm thus regulates Fgf8 in the ectoderm and the role of the endoderm in pharyngeal arch patterning may thus be indirectly mediated by the ectoderm...
Molar tooth development in caspase-3 deficient miceEva Matalova
Laboratory of Animal Embryology, Institute of Animal Physiology and Genetics, Academy of Sciences, Brno, Czech Republic
Int J Dev Biol 50:491-7. 2006..The results suggest that although caspase-3 becomes activated and may be essential for dental apoptosis, it does not seem fundamental for formation of normal mineralised molar teeth...
Ror2 knockout mouse as a model for the developmental pathology of autosomal recessive Robinow syndromeGeorg C Schwabe
Max Planck Institute for Molecular Genetics, Berlin, Germany
Dev Dyn 229:400-10. 2004..The Ror2(-/-) mouse provides a suitable model that may help to explain many of the underlying developmental malformations in individuals with Robinow syndrome...
Bapx1 regulates patterning in the middle ear: altered regulatory role in the transition from the proximal jaw during vertebrate evolutionAbigail S Tucker
Department of Craniofacial Development and Orthodontics, Kings College London, Floor 28, Guy s Tower, Guy s Hospital, London SE1 9RT, UK
Development 131:1235-45. 2004....
Traf6 is essential for murine tooth cusp morphogenesisAtsushi Ohazama
Department of Craniofacial Development, GKT Dental Institute, King s College, Guy s Hospital, London Bridge, London, United Kingdom
Dev Dyn 229:131-5. 2004..Developmental Dynamics 229:131-135, 2004...
Mouse models of tooth abnormalitiesJana Fleischmannova
Laboratory of Animal Embryology, Institute of Animal Physiology and Genetics, Academy of Sciences, Brno, Czech Republic
Eur J Oral Sci 116:1-10. 2008..This review aims to summarize recent knowledge obtained in mouse models, which can be used to gain a better understanding of the molecular basis of human dental abnormalities...
Initiation and patterning of the snake dentition are dependent on Sonic hedgehog signalingMarcela Buchtová
Department of Oral Health Sciences, University of British Columbia, Vancouver, BC, Canada
Dev Biol 319:132-45. 2008..In summary, we have found diverse roles for Shh in patterning the snake dentition but, have excluded the participation of this signal in replacement tooth formation...
Apoptosis of premigratory neural crest cells in rhombomeres 3 and 5: consequences for patterning of the branchial regionDebra L Ellies
MRC Centre for Developmental Neurobiology, 4th Floor New Hunts House, King s College London, Guy s Hospital, London, United Kingdom
Dev Biol 251:118-28. 2002..Thus, apoptosis in the odd-numbered rhombomeres appears to be an evolutionarily derived mechanism that is required to eliminate r3 and r5 crest migration into first and third arches and thereby remove these muscle attachment sites...
Tooth development is independent of a Hox patterning programmeChela T James
Department of Craniofacial Development, GKT Dental Institute, Kings College London, Guy s Hospital, London Bridge, London, United Kingdom
Dev Dyn 225:332-5. 2002..We propose that the evolutionary development of teeth in the first branchial arch is independent of the loss of Hox expression necessary for the development of the jaw...
No evidence for ventrally migrating neural tube cells from the mid- and hindbrainMay Yaneza
MRC Centre for Developmental Neurobiology, King's College London, Guy's Hospital, London, United Kingdom
Dev Dyn 223:163-7. 2002..No GFP-expressing cells were detected emigrating from the ventral neural tube from E3 to E5. Our findings are, thus, in disagreement with those of previous studies, which have indicated the existence of VENT cells in the cranial region...
