Anthony J Strong

Summary

Affiliation: King's College London
Country: UK

Publications

  1. ncbi request reprint Spreading and synchronous depressions of cortical activity in acutely injured human brain
    Anthony J Strong
    Departments of Neurosurgery, King s College London, London, United Kingdom
    Stroke 33:2738-43. 2002
  2. ncbi request reprint Application of rapid-sampling, online microdialysis to the monitoring of brain metabolism during aneurysm surgery
    Robin Bhatia
    Department of Clinical Neurosciences, Kings College London, GKT School of Medicine, Kings Denmark Hill Campus, London, England
    Neurosurgery 58:ONS-313-20; discussion ONS-321. 2006
  3. doi request reprint Repetitive cortical spreading depolarizations in a case of severe brain trauma
    Jed A Hartings
    Division of Psychiatry and Neuroscience, Walter Reed Army Institute of Research, Silver Spring, MD 20910, USA
    Neurol Res 30:876-82. 2008
  4. ncbi request reprint Dr. Bernice Grafstein's paper on the mechanism of spreading depression
    Anthony J Strong
    J Neurophysiol 94:5-7. 2005
  5. ncbi request reprint Treatment of critical care patients with substantial acute ischemic or traumatic brain injury
    Anthony J Strong
    Crit Care Med 33:2147-9; author reply 2149. 2005
  6. pmc Cortical spreading ischemia in the absence of proximal vasospasm after aneurysmal subarachnoid hemorrhage: evidence for a dual mechanism of delayed cerebral ischemia
    Anthony J Strong
    King s College London, Department of Clinical Neuroscience, Institute of Psychiatry, London, UK
    J Cereb Blood Flow Metab 32:201-2. 2012
  7. ncbi request reprint Peri-infarct depolarizations lead to loss of perfusion in ischaemic gyrencephalic cerebral cortex
    Anthony J Strong
    King s College London, Department of Clinical Neurosciences Neurosurgery, UK
    Brain 130:995-1008. 2007
  8. ncbi request reprint Cortical spreading depression: an adverse but treatable factor in intensive care?
    Anthony J Strong
    King s College London, Department of Clinical Neurosciences, London, UK
    Curr Opin Crit Care 13:126-33. 2007
  9. ncbi request reprint Evaluation of laser speckle flowmetry for imaging cortical perfusion in experimental stroke studies: quantitation of perfusion and detection of peri-infarct depolarisations
    Anthony J Strong
    King s College London, Department of Clinical Neurosciences Neurosurgery, London, UK
    J Cereb Blood Flow Metab 26:645-53. 2006
  10. ncbi request reprint Transient changes in cortical glucose and lactate levels associated with peri-infarct depolarisations, studied with rapid-sampling microdialysis
    Sarah E Hopwood
    Department of Clinical Neurosciences, Section of Neurosurgery, King s College, London, UK
    J Cereb Blood Flow Metab 25:391-401. 2005

Collaborators

Detail Information

Publications18

  1. ncbi request reprint Spreading and synchronous depressions of cortical activity in acutely injured human brain
    Anthony J Strong
    Departments of Neurosurgery, King s College London, London, United Kingdom
    Stroke 33:2738-43. 2002
    ..This study sought clear evidence for the occurrence and propagation of CSD in the injured human brain...
  2. ncbi request reprint Application of rapid-sampling, online microdialysis to the monitoring of brain metabolism during aneurysm surgery
    Robin Bhatia
    Department of Clinical Neurosciences, Kings College London, GKT School of Medicine, Kings Denmark Hill Campus, London, England
    Neurosurgery 58:ONS-313-20; discussion ONS-321. 2006
    ..To introduce rapid-sampling microdialysis for the early detection of adverse metabolic changes in tissue at risk during aneurysm surgery...
  3. doi request reprint Repetitive cortical spreading depolarizations in a case of severe brain trauma
    Jed A Hartings
    Division of Psychiatry and Neuroscience, Walter Reed Army Institute of Research, Silver Spring, MD 20910, USA
    Neurol Res 30:876-82. 2008
    ..Here we performed multi-modal cerebral monitoring to investigate pathologies associated with CSD occurrence in a case of severe traumatic brain injury...
  4. ncbi request reprint Dr. Bernice Grafstein's paper on the mechanism of spreading depression
    Anthony J Strong
    J Neurophysiol 94:5-7. 2005
  5. ncbi request reprint Treatment of critical care patients with substantial acute ischemic or traumatic brain injury
    Anthony J Strong
    Crit Care Med 33:2147-9; author reply 2149. 2005
  6. pmc Cortical spreading ischemia in the absence of proximal vasospasm after aneurysmal subarachnoid hemorrhage: evidence for a dual mechanism of delayed cerebral ischemia
    Anthony J Strong
    King s College London, Department of Clinical Neuroscience, Institute of Psychiatry, London, UK
    J Cereb Blood Flow Metab 32:201-2. 2012
    ..That such events can occur in the substantial absence of proximal vasospasm is compatible with this concept, but the preliminary evidence needs support from more extensive studies...
  7. ncbi request reprint Peri-infarct depolarizations lead to loss of perfusion in ischaemic gyrencephalic cerebral cortex
    Anthony J Strong
    King s College London, Department of Clinical Neurosciences Neurosurgery, UK
    Brain 130:995-1008. 2007
    ..The findings suggest that such events play a central rather than a subsidiary role in cerebral infarction in the gyrencephalic brain...
  8. ncbi request reprint Cortical spreading depression: an adverse but treatable factor in intensive care?
    Anthony J Strong
    King s College London, Department of Clinical Neurosciences, London, UK
    Curr Opin Crit Care 13:126-33. 2007
    ....
  9. ncbi request reprint Evaluation of laser speckle flowmetry for imaging cortical perfusion in experimental stroke studies: quantitation of perfusion and detection of peri-infarct depolarisations
    Anthony J Strong
    King s College London, Department of Clinical Neurosciences Neurosurgery, London, UK
    J Cereb Blood Flow Metab 26:645-53. 2006
    ....
  10. ncbi request reprint Transient changes in cortical glucose and lactate levels associated with peri-infarct depolarisations, studied with rapid-sampling microdialysis
    Sarah E Hopwood
    Department of Clinical Neurosciences, Section of Neurosurgery, King s College, London, UK
    J Cereb Blood Flow Metab 25:391-401. 2005
    ..001). The results also characterise a metabolic signature for PIDs for possible application in clinical work, and emphasise potential risks in the use of insulin to control plasma glucose in patients with brain injury...
  11. pmc Dynamic metabolic response to multiple spreading depolarizations in patients with acute brain injury: an online microdialysis study
    Delphine Feuerstein
    Department of Bioengineering, Imperial College London, London, UK
    J Cereb Blood Flow Metab 30:1343-55. 2010
    ..Such a failure would compromise cellular repolarization and hence tissue viability. The findings offer a new mechanism to account for otherwise unexplained instances of depletion of brain microdialysate glucose...
  12. doi request reprint Persisting depletion of brain glucose following cortical spreading depression, despite apparent hyperaemia: evidence for risk of an adverse effect of Leão's spreading depression
    Parastoo Hashemi
    Department of Bioengineering, Imperial College, London, UK
    J Cereb Blood Flow Metab 29:166-75. 2009
    ....
  13. ncbi request reprint Dynamic changes in brain glucose and lactate in pericontusional areas of the human cerebral cortex, monitored with rapid sampling on-line microdialysis: relationship with depolarisation-like events
    Mark Parkin
    Department of Chemistry, Kings College London, Strand, London, UK
    J Cereb Blood Flow Metab 25:402-13. 2005
    ..76, P=0.0004, n=11). It is proposed that the recently documented adverse impact of low dialysate glucose on clinical outcome may be because of recurrent, spontaneous spreading-depression-like events in the perilesion cortex...
  14. ncbi request reprint Detection of spreading depolarization with intraparenchymal electrodes in the injured human brain
    Toby Jeffcote
    Department of Neurosurgery, King s College Hospital, London, UK
    Neurocrit Care 20:21-31. 2014
    ..This study examined whether these events can be detected using intra-cortical electrodes, opening the way for electrode insertion via burr hole...
  15. pmc Association of seizures with cortical spreading depression and peri-infarct depolarisations in the acutely injured human brain
    Martin Fabricius
    Department of Clinical Neurophysiology, Glostrup Hospital, Nordre Ringvej, 2600 Glostrup, Denmark
    Clin Neurophysiol 119:1973-84. 2008
    ....
  16. doi request reprint Spreading depolarizations occur in human ischemic stroke with high incidence
    Christian Dohmen
    Department of Neurology, University of Cologne, Cologne, Germany
    Ann Neurol 63:720-8. 2008
    ..For decades it has been questioned whether CSD or PID occur in human ischemic stroke. Here, we describe CSD and PID in patients with malignant middle cerebral artery infarction detected by subdural electrocorticography (ECoG)...
  17. ncbi request reprint Delayed ischaemic neurological deficits after subarachnoid haemorrhage are associated with clusters of spreading depolarizations
    Jens P Dreier
    Department of Experimental Neurology and Neurology, Charite University Medicine, Berlin, Germany
    Brain 129:3224-37. 2006
    ..In view of experimental evidence and the present clinical results, we suggest that spreading depolarizations with prolonged depressions are a promising target for treatment development in SAH and ischaemic stroke...
  18. ncbi request reprint Cortical spreading depression and peri-infarct depolarization in acutely injured human cerebral cortex
    Martin Fabricius
    Department of Clinical Neurophysiology, Glostrup Hospital, University of Copenhagen, Denmark
    Brain 129:778-90. 2006
    ..We hypothesize that the depolarization events might contribute to tissue damage in acute disorders in the human brain...