Mena Soory

Summary

Affiliation: King's College London
Country: UK

Publications

  1. ncbi Oxidant/antioxidant interactions of nicotine, Coenzyme Q10, Pycnogenol and phytoestrogens in oral periosteal fibroblasts and MG63 osteoblasts
    Elena Figuero
    Department of Periodontology, Faculty of Dentistry, University Complutense of Madrid, Spain
    Steroids 71:1062-72. 2006
  2. pmc Mechanisms for redox actions of nicotine and glutathione in cell culture, relevant to periodontitis
    Federico Tinti
    Formerly at King s College London Dental Institute, Periodontology, Guy s Dental Hospital, London, UK
    Sci Rep 2:566. 2012
  3. pmc A role for non-antimicrobial actions of tetracyclines in combating oxidative stress in periodontal and metabolic diseases: a literature review
    M Soory
    Periodontology, King s College London Dental Institute at G KT Hospitals, King s College Dental Hospital, Denmark Hill, London SE 5 9RW, UK
    Open Dent J 2:5-12. 2008
  4. ncbi Associations between periodontitis and systemic inflammatory diseases: response to treatment
    Una El-Shinnawi
    Periodontology, King s College London Dental Institute, Denmark Hill, London SE5 9RW, UK
    Recent Pat Endocr Metab Immune Drug Discov 7:169-88. 2013
  5. ncbi Nutritional antioxidants and their applications in cardiometabolic diseases
    Mena Soory
    Periodontology, King s College London Dental Institute, Denmark Hill, London SE5 9RW, UK
    Infect Disord Drug Targets 12:388-401. 2012
  6. ncbi Inflammatory mechanisms and redox status in periodontal and cardiometabolic diseases: effects of adjunctive nutritional antioxidants and statins
    Mena Soory
    Periodontology, King s College London Dental Institute, Denmark Hill, London SE 5 9RW, UK
    Infect Disord Drug Targets 12:301-15. 2012
  7. ncbi Anabolic potential of fibroblasts from chronically inflamed gingivae grown in a hyperglycemic culture medium in the presence or absence of insulin and nicotine
    M Soory
    Department of Periodontology, Guy s King s and St Thomas Dental Institute, King s College Dental Hospital, London, UK
    J Periodontol 74:1771-7. 2003
  8. ncbi Phenytoin-mediated androgen metabolism in gingival fibroblasts. Effects of the antiandrogen finasteride and the alkaline phosphatase inhibitor levamisole
    M Soory
    Division of Periodontology, Guy s, King s and St Thomas Dental Institute, King s Dental Hospital, London, UK
    J Clin Periodontol 29:955-60. 2002
  9. ncbi Periodontal diseases and rheumatoid arthritis: a coincident model for therapeutic intervention?
    Mena Soory
    King s College London Dental Institute at Guy s King s and St Thomas Hospitals, King s College Dental Hospital, Denmark Hill, London, UK
    Curr Drug Metab 8:750-7. 2007
  10. ncbi Periodontal disease severity and systemic diseases prevalent in a Caribbean catchment area of patients
    M Soory
    King s College London Dental Institute, King s College Dental Hospital, Denmark Hill, London SE5 9RW, United Kingdom
    West Indian Med J 56:190-3. 2007

Collaborators

  • Douglas T Clark
  • Una El-Shinnawi
  • Federico Tinti
  • Aruni Tilakaratne
  • Elena Figuero
  • Z A Rahman
  • Antonio Bascones
  • Rocio Cerero

Detail Information

Publications25

  1. ncbi Oxidant/antioxidant interactions of nicotine, Coenzyme Q10, Pycnogenol and phytoestrogens in oral periosteal fibroblasts and MG63 osteoblasts
    Elena Figuero
    Department of Periodontology, Faculty of Dentistry, University Complutense of Madrid, Spain
    Steroids 71:1062-72. 2006
    ..The aim of this investigation was to evaluate potential oxidant/antioxidant interactions of nicotine with antioxidants (Coenzyme Q10 (CoQ), Pycnogenol and phytoestrogens in a cell culture model...
  2. pmc Mechanisms for redox actions of nicotine and glutathione in cell culture, relevant to periodontitis
    Federico Tinti
    Formerly at King s College London Dental Institute, Periodontology, Guy s Dental Hospital, London, UK
    Sci Rep 2:566. 2012
    ..Down-regulation of 5α-reductase activity by nicotine resulting in reduced yields of DHT was overcome by glutathione. Overcoming oxidative stress in a redox environment is applicable to treatment outcome...
  3. pmc A role for non-antimicrobial actions of tetracyclines in combating oxidative stress in periodontal and metabolic diseases: a literature review
    M Soory
    Periodontology, King s College London Dental Institute at G KT Hospitals, King s College Dental Hospital, Denmark Hill, London SE 5 9RW, UK
    Open Dent J 2:5-12. 2008
    ..The diverse mechanisms of action of tetracyclines in overcoming oxidative stress and enhancing matrix synthesis are discussed in this review...
  4. ncbi Associations between periodontitis and systemic inflammatory diseases: response to treatment
    Una El-Shinnawi
    Periodontology, King s College London Dental Institute, Denmark Hill, London SE5 9RW, UK
    Recent Pat Endocr Metab Immune Drug Discov 7:169-88. 2013
    ..This article includes an appraisal of patents and their applications. ..
  5. ncbi Nutritional antioxidants and their applications in cardiometabolic diseases
    Mena Soory
    Periodontology, King s College London Dental Institute, Denmark Hill, London SE5 9RW, UK
    Infect Disord Drug Targets 12:388-401. 2012
    ..It would be critical to formulate optimal proportions and their combinations for therapeutic efficacy, based on synergistic interactions. Some of these mechanisms and potential actions are discussed...
  6. ncbi Inflammatory mechanisms and redox status in periodontal and cardiometabolic diseases: effects of adjunctive nutritional antioxidants and statins
    Mena Soory
    Periodontology, King s College London Dental Institute, Denmark Hill, London SE 5 9RW, UK
    Infect Disord Drug Targets 12:301-15. 2012
    ..Accurate therapeutic targeting as an adjunct to conventional periodontal treatment in this context, for mutual benefit to subjects with periodontitis and cardiometabolic diseases is a challenge...
  7. ncbi Anabolic potential of fibroblasts from chronically inflamed gingivae grown in a hyperglycemic culture medium in the presence or absence of insulin and nicotine
    M Soory
    Department of Periodontology, Guy s King s and St Thomas Dental Institute, King s College Dental Hospital, London, UK
    J Periodontol 74:1771-7. 2003
    ..The aim of this investigation was to use a hyperglycemic cell-culture model to study the anabolic products of androgen metabolism in fibroblasts in response to insulin and nicotine...
  8. ncbi Phenytoin-mediated androgen metabolism in gingival fibroblasts. Effects of the antiandrogen finasteride and the alkaline phosphatase inhibitor levamisole
    M Soory
    Division of Periodontology, Guy s, King s and St Thomas Dental Institute, King s Dental Hospital, London, UK
    J Clin Periodontol 29:955-60. 2002
    ....
  9. ncbi Periodontal diseases and rheumatoid arthritis: a coincident model for therapeutic intervention?
    Mena Soory
    King s College London Dental Institute at Guy s King s and St Thomas Hospitals, King s College Dental Hospital, Denmark Hill, London, UK
    Curr Drug Metab 8:750-7. 2007
    ..Therapeutic interventions relevant to both diseases discussed in this review, have scope for a double hit in periodontal patients with co-existing RA and vice versa...
  10. ncbi Periodontal disease severity and systemic diseases prevalent in a Caribbean catchment area of patients
    M Soory
    King s College London Dental Institute, King s College Dental Hospital, Denmark Hill, London SE5 9RW, United Kingdom
    West Indian Med J 56:190-3. 2007
    ..To describe associations between the prevalence of periodontal disease severity and co-existence of systemic disease(s) and a smoking habit amongst periodontal referrals in a Caribbean catchment area of patients...
  11. ncbi Redox status in periodontal and systemic inflammatory conditions including associated neoplasias: antioxidants as adjunctive therapy?
    Mena Soory
    Periodontology, King s College London Dental Institute, Denmark Hill, London SE 5 9RW, UK
    Infect Disord Drug Targets 9:415-27. 2009
    ..Formulation of therapeutic agents shown to have efficacy in this context, with accurate targeting is a challenge...
  12. ncbi Osteoblastic responses to LPS, glucose-oxidised LDL and minocycline: therapeutic targets for periodontal and cardiometabolic diseases
    Aruni Tilakaratne
    Department of Oral Medicine and Periodontology, University of Peradeniya Sri Lanka
    Recent Pat Endocr Metab Immune Drug Discov 6:73-84. 2012
    ..The clinical relevance of this concept in periodontitis patients with cardiometabolic risk markers is addressed...
  13. ncbi Effects of alkaline phosphatase and its inhibitor levamisole on the modulation of androgen metabolism by nicotine and minocycline in human gingival and oral periosteal fibroblasts
    M Soory
    Division of Periodontology, Guy s King s and St Thomas Dental Institute, King s Dental Hospital, Caldecot Road, SE5 9RW, London, UK
    Arch Oral Biol 48:69-76. 2003
    ..01). L also caused further inhibition in the yields of androgen metabolites when incubated with nicotine, implying that some of the inhibitory effects of nicotine could be due to inhibition of AP activity...
  14. ncbi Modulation of androgen metabolism by phenytoin, oestradiol and tamoxifen in human gingival fibroblasts
    M Soory
    Department of Periodontology, GKT, King s Dental Hospital, London, UK
    J Clin Periodontol 30:556-61. 2003
    ....
  15. ncbi Androgen metabolic response to indomethacin and the alkaline phosphatase inhibitor levamisole in fibroblasts
    M Soory
    Division of Periodontology, Guy s King s and St Thomas Dental Institute, King s College Dental Hospital, Caldecot Road, London, UK
    J Clin Periodontol 30:1069-74. 2003
    ..Chronically inflamed human gingival fibroblasts (HGF) were used to demonstrate the comparative effects of L on HGF and human oral periosteal fibroblasts (HPF)...
  16. ncbi Relevance of nutritional antioxidants in metabolic syndrome, ageing and cancer: potential for therapeutic targeting
    Mena Soory
    Periodontology, King s College London Dental Institute, King s College Dental Hospital, Denmark Hill, London SE5 9RW, UK
    Infect Disord Drug Targets 9:400-14. 2009
    ..Some of these mechanisms and potential therapeutic targets are discussed...
  17. ncbi The effects of human mast-cell products and of phenytoin on androgen 5alpha-reductase expression in human gingival fibroblasts
    M Soory
    Division of Periodontology, Guy s King s and St Thomas Dental Institute, King s Campus, Caldecot Road, SE5 9RW, London, UK
    Arch Oral Biol 46:847-55. 2001
    ..The findings suggest a novel hypothesis that mast-cell mediated androgen action in the gingiva in response to phenytoin could contribute to gingival overgrowth...
  18. ncbi The influence of cholesterol, progesterone, 4-androstenedione and testosterone on the growth of Treponema denticola ATCC 33520 in batch cultures
    Douglas T Clark
    Department of Microbiology, King s College London Dental Institute at Guy s, King s College and St Thomas Hospitals, Floor 17 Guy s Tower, London SE1 9RS, UK
    Anaerobe 12:267-73. 2006
    ..001microg/mL of progesterone. The potential of the hormonal steroids to inhibit growth was in the order of progesterone, 4-androstenedione and testosterone...
  19. ncbi The metabolism of cholesterol and certain hormonal steroids by Treponema denticola
    Douglas T Clark
    Department of Microbiology, King s College London Dental Institute at Guy s, King s College and St Thomas Hospitals, UK
    Steroids 71:352-63. 2006
    ..denticola utilising host supplied steroids as growth factors and T. denticola steroid metabolism acting as a virulence factor...
  20. ncbi Antioxidant effects of glutathione and IGF in a hyperglycaemic cell culture model of fibroblasts: some actions of advanced glycaemic end products (AGE) and nicotine
    Z A Rahman
    Department of Periodontology, King s College London Dental Institute, Guy s Dental Hospital, London, UK
    Endocr Metab Immune Disord Drug Targets 6:279-86. 2006
    ..These agents affected yields of androgen metabolites, biomarkers of oxidative stress and repair, with potential implications on healing in uncontrolled diabetic smokers...
  21. ncbi Steroid 5alpha-reductase activity of Treponema denticola
    D T Clark
    Department of Microbiology, King s College London Dental Institute at Guy s, King s College and St Thomas Hospitals, London, UK
    Oral Microbiol Immunol 22:326-32. 2007
    ..denticola ATCC 35405. The aim of the work presented here was to optimize assay conditions and determine steroid substrate specificities for the 5alpha-R activity of T. denticola ATCC 33520...
  22. ncbi Hormone mediation of immune responses in the progression of diabetes, rheumatoid arthritis and periodontal diseases
    M Soory
    Division of Periodontology, Guy s King s and St Thomas Dental Institute, King s Dental Hospital, Caldecot Road, London SE5 9RW, United Kingdom
    Curr Drug Targets Immune Endocr Metabol Disord 2:13-25. 2002
    ..Hormone replacement therapy could be another facet in a multifaceted treatment approach in these patients, where indicated...
  23. ncbi Targets for steroid hormone mediated actions of periodontal pathogens, cytokines and therapeutic agents: some implications on tissue turnover in the periodontium
    M Soory
    Division of Periodontology, Guy s King s and St Thomas Dental Institute, King s Campus, Caldecot Road, London SE5 9RW, United Kingdom
    Curr Drug Targets 1:309-25. 2000
    ..Cell dynamics of the periodontium plays an important role in co-ordinating the diverse interactions between steroid hormones and therapeutic agents...