Andrew K Snabaitis

Summary

Affiliation: King's College London
Country: UK

Publications

  1. pmc Evidence for direct regulation of myocardial Na+/H+ exchanger isoform 1 phosphorylation and activity by 90-kDa ribosomal S6 kinase (RSK): effects of the novel and specific RSK inhibitor fmk on responses to alpha1-adrenergic stimulation
    Friederike Cuello
    Cardiovascular Division, King s College London, United Kingdom
    Mol Pharmacol 71:799-806. 2007
  2. doi Protein kinase B/Akt phosphorylates and inhibits the cardiac Na+/H+ exchanger NHE1
    Andrew K Snabaitis
    Cardiovascular Division, King s College London, The Rayne Institute, St Thomas Hospital, London SE1 7EH, United Kingdom
    Circ Res 103:881-90. 2008
  3. ncbi Stimulation of the plasma membrane Na+/H+ exchanger NHE1 by sustained intracellular acidosis. Evidence for a novel mechanism mediated by the ERK pathway
    Robert S Haworth
    Centre for Cardiovascular Biology and Medicine, King s College London, The Rayne Institute, St Thomas Hospital, London SE1 7EH, United Kingdom
    J Biol Chem 278:31676-84. 2003
  4. ncbi A novel role for protein phosphatase 2A in receptor-mediated regulation of the cardiac sarcolemmal Na+/H+ exchanger NHE1
    Andrew K Snabaitis
    Cardiovascular Division, King s College London, London SE1 7EH, UK
    J Biol Chem 281:20252-62. 2006
  5. ncbi Regulation of the extracellular signal-regulated kinase pathway in adult myocardium: differential roles of G(q/11), Gi and G(12/13) proteins in signalling by alpha1-adrenergic, endothelin-1 and thrombin-sensitive protease-activated receptors
    Andrew K Snabaitis
    Cardiovascular Division, King s College London, The Rayne Institute, St Thomas Hospital, London, SE1 7EH, United Kingdom
    Cell Signal 17:655-64. 2005
  6. ncbi Regulation of sarcolemmal Na(+)/H(+) exchange by hydrogen peroxide in adult rat ventricular myocytes
    Andrew K Snabaitis
    Centre for Cardiovascular Biology and Medicine, King s College London, The Rayne Institute, St Thomas Hospital, London SE1 7EH, UK
    Cardiovasc Res 53:470-80. 2002
  7. ncbi Inhibition of the Na+/H+ exchanger attenuates the deterioration of ventricular function during pacing-induced heart failure in rabbits
    Stephanie Aker
    Institute of Pathophysiology, University of Essen Medical School, Hufelandstrasse 55, Essen 45122, Germany
    Cardiovasc Res 63:273-82. 2004

Collaborators

Detail Information

Publications7

  1. pmc Evidence for direct regulation of myocardial Na+/H+ exchanger isoform 1 phosphorylation and activity by 90-kDa ribosomal S6 kinase (RSK): effects of the novel and specific RSK inhibitor fmk on responses to alpha1-adrenergic stimulation
    Friederike Cuello
    Cardiovascular Division, King s College London, United Kingdom
    Mol Pharmacol 71:799-806. 2007
    ..These findings reveal, for the first time to our knowledge, that RSK is the principal regulator of NHE1 phosphorylation and activity after alpha1-adrenergic stimulation in adult myocardium...
  2. doi Protein kinase B/Akt phosphorylates and inhibits the cardiac Na+/H+ exchanger NHE1
    Andrew K Snabaitis
    Cardiovascular Division, King s College London, The Rayne Institute, St Thomas Hospital, London SE1 7EH, United Kingdom
    Circ Res 103:881-90. 2008
    ....
  3. ncbi Stimulation of the plasma membrane Na+/H+ exchanger NHE1 by sustained intracellular acidosis. Evidence for a novel mechanism mediated by the ERK pathway
    Robert S Haworth
    Centre for Cardiovascular Biology and Medicine, King s College London, The Rayne Institute, St Thomas Hospital, London SE1 7EH, United Kingdom
    J Biol Chem 278:31676-84. 2003
    ....
  4. ncbi A novel role for protein phosphatase 2A in receptor-mediated regulation of the cardiac sarcolemmal Na+/H+ exchanger NHE1
    Andrew K Snabaitis
    Cardiovascular Division, King s College London, London SE1 7EH, UK
    J Biol Chem 281:20252-62. 2006
    ....
  5. ncbi Regulation of the extracellular signal-regulated kinase pathway in adult myocardium: differential roles of G(q/11), Gi and G(12/13) proteins in signalling by alpha1-adrenergic, endothelin-1 and thrombin-sensitive protease-activated receptors
    Andrew K Snabaitis
    Cardiovascular Division, King s College London, The Rayne Institute, St Thomas Hospital, London, SE1 7EH, United Kingdom
    Cell Signal 17:655-64. 2005
    ..We conclude that full activation of the ERK pathway in ARVM by alpha1-adrenergic, ET-1 and thrombin receptors requires the activation of distinct families of heterotrimeric G proteins...
  6. ncbi Regulation of sarcolemmal Na(+)/H(+) exchange by hydrogen peroxide in adult rat ventricular myocytes
    Andrew K Snabaitis
    Centre for Cardiovascular Biology and Medicine, King s College London, The Rayne Institute, St Thomas Hospital, London SE1 7EH, UK
    Cardiovasc Res 53:470-80. 2002
    ....
  7. ncbi Inhibition of the Na+/H+ exchanger attenuates the deterioration of ventricular function during pacing-induced heart failure in rabbits
    Stephanie Aker
    Institute of Pathophysiology, University of Essen Medical School, Hufelandstrasse 55, Essen 45122, Germany
    Cardiovasc Res 63:273-82. 2004
    ..Conclusion: NHE-inhibition attenuates the functional, morphological and biochemical derangements of pacing-induced HF in rabbits...