Lyn Smurthwaite

Summary

Affiliation: King's College London
Country: UK

Publications

  1. ncbi request reprint Local IgE synthesis in allergic rhinitis and asthma
    Lyn Smurthwaite
    The Randall Centre for Molecular Mechanisms of Cell Function, King s College London, Guy s Campus, St Thomas Street, SE1 9RT, UK
    Curr Allergy Asthma Rep 2:231-8. 2002
  2. ncbi request reprint The biology of IGE and the basis of allergic disease
    Hannah J Gould
    The Randall Centre, King s College London, United Kingdom
    Annu Rev Immunol 21:579-628. 2003
  3. ncbi request reprint Class switch recombination to IgE in the bronchial mucosa of atopic and nonatopic patients with asthma
    Pooja Takhar
    Randall Division of Cell and Molecular Biophysics, King s College London, UK
    J Allergy Clin Immunol 119:213-8. 2007
  4. ncbi request reprint Increases in allergen-specific IgE in BAL after segmental allergen challenge in atopic asthmatics
    Duncan R Wilson
    Upper Respiratory Medicine, Imperial College School of Medicine at the National Heart and Lung Institute, London, United Kingdom
    Am J Respir Crit Care Med 165:22-6. 2002
  5. ncbi request reprint Allergen drives class switching to IgE in the nasal mucosa in allergic rhinitis
    Pooja Takhar
    The Randall Division, King s College London, London, United Kingdom
    J Immunol 174:5024-32. 2005

Collaborators

Detail Information

Publications6

  1. ncbi request reprint Local IgE synthesis in allergic rhinitis and asthma
    Lyn Smurthwaite
    The Randall Centre for Molecular Mechanisms of Cell Function, King s College London, Guy s Campus, St Thomas Street, SE1 9RT, UK
    Curr Allergy Asthma Rep 2:231-8. 2002
    ....
  2. ncbi request reprint The biology of IGE and the basis of allergic disease
    Hannah J Gould
    The Randall Centre, King s College London, United Kingdom
    Annu Rev Immunol 21:579-628. 2003
    ..Effective mechanisms ensure that allergic reactions are confined to mucosal tissues, thereby minimizing the risk of systemic anaphylaxis...
  3. ncbi request reprint Class switch recombination to IgE in the bronchial mucosa of atopic and nonatopic patients with asthma
    Pooja Takhar
    Randall Division of Cell and Molecular Biophysics, King s College London, UK
    J Allergy Clin Immunol 119:213-8. 2007
    ..It is generally believed that class switch recombination occurs in lymphoid tissue, but it was recently shown that class switching to IgE occurs in the nasal mucosa in allergic rhinitis...
  4. ncbi request reprint Increases in allergen-specific IgE in BAL after segmental allergen challenge in atopic asthmatics
    Duncan R Wilson
    Upper Respiratory Medicine, Imperial College School of Medicine at the National Heart and Lung Institute, London, United Kingdom
    Am J Respir Crit Care Med 165:22-6. 2002
    ..These data indicate that allergen provocation results in a selective local accumulation of isotype-specific and allergen-specific IgE antibody within the bronchi, independent of alterations in circulating IgE...
  5. ncbi request reprint Allergen drives class switching to IgE in the nasal mucosa in allergic rhinitis
    Pooja Takhar
    The Randall Division, King s College London, London, United Kingdom
    J Immunol 174:5024-32. 2005
    ..These results demonstrate that allergen stimulates local CSR to IgE, revealing a potential target for topical therapies in allergic rhinitis...