Lyn Smurthwaite

Summary

Affiliation: King's College London
Country: UK

Publications

  1. ncbi Local IgE synthesis in allergic rhinitis and asthma
    Lyn Smurthwaite
    The Randall Centre for Molecular Mechanisms of Cell Function, King s College London, Guy s Campus, St Thomas Street, SE1 9RT, UK
    Curr Allergy Asthma Rep 2:231-8. 2002
  2. ncbi The biology of IGE and the basis of allergic disease
    Hannah J Gould
    The Randall Centre, King s College London, United Kingdom
    Annu Rev Immunol 21:579-628. 2003
  3. ncbi Class switch recombination to IgE in the bronchial mucosa of atopic and nonatopic patients with asthma
    Pooja Takhar
    Randall Division of Cell and Molecular Biophysics, King s College London, UK
    J Allergy Clin Immunol 119:213-8. 2007
  4. ncbi Increases in allergen-specific IgE in BAL after segmental allergen challenge in atopic asthmatics
    Duncan R Wilson
    Upper Respiratory Medicine, Imperial College School of Medicine at the National Heart and Lung Institute, London, United Kingdom
    Am J Respir Crit Care Med 165:22-6. 2002
  5. ncbi Allergen drives class switching to IgE in the nasal mucosa in allergic rhinitis
    Pooja Takhar
    The Randall Division, King s College London, London, United Kingdom
    J Immunol 174:5024-32. 2005
  6. ncbi British Guideline on the Management of Asthma
    Graham Douglas
    Thorax 63:iv1-121. 2008

Collaborators

  • Stephen R Durham
  • Tak H Lee
  • Hannah J Gould
  • Natalie McCloskey
  • D B Price
  • Graham Devereux
  • Janet Rimmer
  • Ian D Pavord
  • H Pinnock
  • Brian J Sutton
  • N Barnes
  • Paul Cullinan
  • Justin J Beilby
  • M Thomas
  • Nicola M Wilson
  • Pooja Takhar
  • Graham Douglas
  • Duncan R Wilson
  • Karen Heslop
  • Mike McKean
  • Brian Smith
  • Graeme Currie
  • Liesl Osman
  • Liam Heaney
  • Cathy Nelson-Piercy
  • Anthony Frew
  • David Bellamy
  • John White
  • Bernard Higgins
  • Anne Boyter
  • Peter Gibson
  • Steve Cunningham
  • Martyn Partridge
  • Chris Brightling
  • Alex Horsley
  • Jon Couriel
  • Dominick Shaw
  • Gary Connett
  • Peter Weller
  • Alison Whittaker
  • Deryn Thompson
  • Nick Innes
  • Monica Fletcher
  • Sheila Edwards
  • Rob Niven
  • David Reilly
  • Savitha Pushparajah
  • Mark Levy
  • Erica Evans
  • Andrew Menzies-Gow
  • Chris Griffiths
  • Chris Cates
  • Mike Shields
  • David Spencer
  • James Paton
  • Sherwood Burge
  • Steve Holmes
  • Sally Welham
  • Elaine Carnegie
  • Michele Hilton Boon
  • Mike Greenstone
  • Ruth McArthur
  • Mike Smith
  • Richard Chavasse
  • Sarah Mayell
  • Richard Russell
  • Colin Robertson
  • John Warner
  • Peter Helms
  • Anne Chang
  • Linda Pearce
  • Safia Qureshi
  • Christopher J Corrigan
  • Graham K Banfield
  • Heather A Coker
  • Victoria A Carr
  • David J Fear
  • Michael Kemp
  • James Hooper
  • Terry G Merrett
  • Eva M Varga
  • Stephen J Till

Detail Information

Publications6

  1. ncbi Local IgE synthesis in allergic rhinitis and asthma
    Lyn Smurthwaite
    The Randall Centre for Molecular Mechanisms of Cell Function, King s College London, Guy s Campus, St Thomas Street, SE1 9RT, UK
    Curr Allergy Asthma Rep 2:231-8. 2002
    ....
  2. ncbi The biology of IGE and the basis of allergic disease
    Hannah J Gould
    The Randall Centre, King s College London, United Kingdom
    Annu Rev Immunol 21:579-628. 2003
    ..Effective mechanisms ensure that allergic reactions are confined to mucosal tissues, thereby minimizing the risk of systemic anaphylaxis...
  3. ncbi Class switch recombination to IgE in the bronchial mucosa of atopic and nonatopic patients with asthma
    Pooja Takhar
    Randall Division of Cell and Molecular Biophysics, King s College London, UK
    J Allergy Clin Immunol 119:213-8. 2007
    ..It is generally believed that class switch recombination occurs in lymphoid tissue, but it was recently shown that class switching to IgE occurs in the nasal mucosa in allergic rhinitis...
  4. ncbi Increases in allergen-specific IgE in BAL after segmental allergen challenge in atopic asthmatics
    Duncan R Wilson
    Upper Respiratory Medicine, Imperial College School of Medicine at the National Heart and Lung Institute, London, United Kingdom
    Am J Respir Crit Care Med 165:22-6. 2002
    ..These data indicate that allergen provocation results in a selective local accumulation of isotype-specific and allergen-specific IgE antibody within the bronchi, independent of alterations in circulating IgE...
  5. ncbi Allergen drives class switching to IgE in the nasal mucosa in allergic rhinitis
    Pooja Takhar
    The Randall Division, King s College London, London, United Kingdom
    J Immunol 174:5024-32. 2005
    ..These results demonstrate that allergen stimulates local CSR to IgE, revealing a potential target for topical therapies in allergic rhinitis...
  6. ncbi British Guideline on the Management of Asthma
    Graham Douglas
    Thorax 63:iv1-121. 2008