Research Topics
Genomes and GenesSpecies | Andrew SimmonsSummaryAffiliation: Kings College London, Institute of Psychiatry Location: London, United Kingdom URL: http://www.kcl.ac.uk/iop/depts/neuroimaging/people/Simmons,DrAndy.aspx Publications: C Tunnard, D Whitehead, C Hurt, L-O Wahlund, P Mecocci, M Tsolaki, B Vellas, C Spenger, I Kloszewska, H Soininen, S Lovestone, A Simmons on behalf of the AddNeuroMed consortium, Apathy and cortical atrophy in Alzheimer’s disease, Int J Ger Psych, 26(7), 741-748, 2011 MR Turner, J Grosskreutz, J Kassubek, S Abrahams, F Agosta, M Benatar, M Filippi, LH Goldstein, M van den Heuvel, S Kalra, D Lule, B Mohammadi, N Atassi, P Bede, H Benali, C Enzinger, L Jelsone-Swain, H-P Muller, RW Orrell, P-F Pradat, J Prudlo, S Ropele, R Sharma, V Silani, A Simmons, S Smith, S Teipel, A Toosy, S Tsermentseli, P Van Damme, E Verstraete, R Welsh, M Wittstock, Towards a neuroimaging biomarker in amyotrophic lateral sclerosis, Lancet Neurology, 10(5), 400-403, 2011 SG Costafreda, ID Dinov, Z Tu, Y Shi, C-Y Liu, I Kloszewska, P Mecocci, H Soininen, M Tsolaki, B Vellas, L-O Wahlund, C Spenger, AW Toga, S Lovestone, A Simmons, on behalf of the AddNeuroMed consortium, Automated hippocampal shape analysis predicts onset of cognitive decline and transition to dementia, Neuroimage, 56(1), 212-219, 2011 A Hamou, A Simmons, M Bauer, B Lewden. A Simmons, Y Zhang, L-O Wahlund, E Westman, M Pritchard, I Kloszewska, P Mecocci, H Soininen, M Tsolaki, B Vellas, S Muehlboeck, A Evans, P Julin, N Sjogren, C Spenger, S Lovestone, F Gwadry-Sridhar and the AddNeuroMed consortium, Cluster analysis of MR imaging in Alzheimer’s disease using decision tree refinement, International Journal of Artificial Intelligence, 6(S11), 90-99, 2011 A Simmons, K Hakansson, Magnetic resonance safety, Methods Mol Biol, 711, 17-28, 2011 C Ginestet, A Simmons, Statistical parametric network (SPN) analysis of functional connectivity dynamics during a working memory task, Neuroimage, 55, 688-704, 2011 E Westman, A Simmons, Y Zhang, J-S Muehlboeck, C Tunnard, Y Liu, L Collins, A Evans, P Meccoci, B Vellas, M Tsolaki, I Kloszewska, H Soininen, S Lovestone, C Spenger, L-O Wahlund for the AddNeuroMed consortium, Multivariate analysis of MRI data for Alzheimer’s disease, mild cognitive impairment and healthy controls, Neuroimage, 54, 1178-1187, 2011 A Simmons, E Westman, S Muehlboeck, P Mecocci, B Vellas, M Tsolaki, I Kloszewska, L-O Wahlund, H Soininen, S Lovestone, A Evans, C Spenger for the AddNeuroMed consortium, The AddNeuroMed framework for multi-centre MRI assessment of longitudinal changes in Alzheimer’s disease : experience from the first 24 months, Int J Ger Psych, 26, 75-82, 2011 2010 A Simmons, Using Imaging Core Labs in Global Multi-Center Clinical Trials, Pharmaceutical Outsourcing, 11(7), 14-17, 2010 E Westman, L-O Wahlund, C Foy, M Poppe, A Cooper, D Murphy, S Lovestone, A Simmons, Combining MRS and MRI measures to distinguish between Alzheimer’s disease and healthy controls, J Alzheimer’s Disease, 22(1), 171-181, 2010 Y Liu, T Paajanen, E Westman, L-O Wahlund, A Simmons, C Tunnard, T Sobow, P Proitsi, J Powell, P Meccoci, M Tsolaki, B Vellas, S Muehlboeck, A Evans, C Spenger, S Lovestone, H Soininen for the AddNeuroMed consortium, Effect of APOE e4 allele on cortical thicknesses and volumes – the AddNeuroMed study, J Alzheimer’s Disease, 21(3), 947-66, 2010 N Ratnarajah, A Simmons, O Davydov, A Hojjatoleslami, A novel white matter fibre tracking algorithm using probabilistic tractography and average curves, Med Image Comput Assist Interv, 13(1), 666-673, 2010 Y Liu, T Paajanen, E Westman, L-O Wahlund, A Simmons, C Tunnard, T Sobow, P Proitsi, J Powell, P Mecocci, M Tsolaki, B Vellas, S Muehlboeck, A Evans, C Spenger, S Lovestone, H Soininen for the AddNeuroMed consortium, APOE e2 allele is associated with larger regional cortical thicknesses and volumes, Dementia and Geriatric Cognitive Disorders, 30(3), 229-237, 2010 M Thambisetty, A Simmons, L Velayudhan, A Hye, J Campbell, Y Zhang, L-O Wahlund, A Kinsey, A Guentert, P Proitsi, J Powell, M Causevic, R Killick, S Lynham, M Broadstock, C Tunnard, R Leung, C Foy, D O’Brien, G Breen, S Furney, M Ward, I Kloszewska, P Mecozzi, H Soininen, M Tsolaki, B Vellas, J Williams, D Murphy, S Parkins, S Resnick, L Ferucci, D Wong, Y Zhou, S Muehlboeck, A Evans, P Francis, C Spenger, S Lovestone for the AddNeuroMed consortium, Clusterin, an amyloid chaperone protein in plasma, is associated with severity, pathology and progression in Alzheimer’s disease, Arch Gen Psych, 67(7), 739-748, 2010 Y Liu, T Paajanen, Y Zhang, E Westman, L-O Wahlund, A Simmons, C Tunnard, T Sobow, P Mecocci, M Tsolaki, B Vellas, S Muehlboeck, A Evans, C Spenger, S Lovestone, H Soininen for the AddNeuroMed consortium, Analysis of regional MRI volumes and thicknesses as predictor of conversion from mild cognitive impairment to Alzheimer’s disease, Neurobiology of Aging, 31(8), 1375-1385, 2010 F Beacher, E Daly, A Simmons,, V Prasher, R Morris, C Robinson, S Lovestone, K Murphy, DG Murphy, Brain anatomy and ageing in non-demented adults with Down’s syndrome : an in vivo MRI study, Psychol Med, 40(4), 611-9, 2010 F Dell’Acqua, P Scifo, G Rizzo M Catani, A Simmons, G Scotti, F Fazio, A modified damped Richardson Lucy algorithm to reduce isotropic background effects in spherical deconvolution, Neuroimage, 49(2), 1446-58, 2010 2009 S Lovestone, P Francis, I Kloszewska, P Mecocci, A Simmons, H Soininen, C Spenger, M Tsolaki, B Vellas, L-O Wahlund, M Ward for the AddNeuroMed consortium, AddNeuroMed – the European collaboration for the discovery of novel biomarkers for Alzheimer’s disease, Annals NYAS, 1180, 36-46, 2009 A Simmons, E Westman, S Muelboeck, P Mecocci, B Vellas, M Tsolaki, I Kloszewska, L-O Wahlund, H Soininen, S Lovestone, A Evans, C Spenger for the AddNeuroMed consortium, MRI measures of Alzheimer’s disease and the AddNeuroMed study, Annals NYAS, 1180, 47-55, 2009 P Premkumar, D Fannon, E Kuipers, ER Peters, APP Anilkumar, A Simmons, V Kumari, Structural magnetic resonance imaging predictors of responsiveness to cognitive behaviour therapy in psychosis, Schizophrenia Res, 115, 146-155, 2009 D Robertson, M Craig, T van Amelsvoort, E Daly, C Moore, A Simmons, M Whitehead, R Morris, D Murphy, Effects of estrogen therapy on age-related differences in gray matter concentration, Climacteric, 12(4), 301-9, 2009 BR Stanton, D Shinhmar, MR Turner, VC Williams, SCR Williams, CRV Blain, VP Giampietro, M Catani, PN Leigh, PM Andersen, A Simmons, Diffusion tensor imaging in sporadic and familial (D90A SOD1) forms of amyotrophic lateral sclerosis, Arch Neurol, 66(1), 109-115, 2009 F Beacher, E Daly, A Simmons, V Prasher, R Morris, C Robinson, S Lovestone, K Murphy, DGM Murphy, Alzheimer’s disease and Down’s syndrome : an in vivo MRI study, Psychological Medicine, 39(4), 675-84, 2009 2008 M Thambisetty, A Hye, C Foy, E Daly, A Glover, A Cooper, A Simmons, D Murphy, S Lovestone, Proteome-based identification of plasma proteins associated with hippocampal metabolism in early Alzheimer’s disease, J Neurology, 255, 1712-1720, 2008(Pubmed) V Kumari, D Fannon, MA Geyer, P Premkumar, E Antonova, A Simmons, E Kuipers, Cortical grey matter volume and sensorimotor gating in Schizophrenia, Cortex, 44(9), 1206-1214, 2008 (Pubmed) P Premkumar, D Fannon, E Kuipers, M Cooke, A Simmons, V Kumari, Association between a longer duration of illness, age and lower frontal lobe grey matter volume in schizophrenia, Behavioural Brain Research, 193(1), 132-9, 2008 (Pubmed) P Premkumar, D Fannon, E Kuipers, A Simmons, S Frangou, V Kumari, Emotional decision making and its dissociable components in schizophrenia : a behavioural and MRI investigation, Neuropsychologia, 46(7), 2002-12, 2008 (Pubmed) 2007 BR Stanton, VS Williams, PN Leigh, SCR Williams, CRV Blain, JM Jarosz, A Simmons, Altered cortical activation during a motor task in ALS : evidence for involvement of central pathways, J Neurology, 254(9), 1260-1267, 2007 (Pubmed) BR Stanton, V Williams, PN Leigh, SCR Williams, CRV Blain, A Simmons, Cortical activation during motor imagery is reduced in amyotrophic lateral sclerosis, Brain Research, 1172, 145-51, 2007 (Pubmed) CRV Blain, VC Williams, C Smallman, BR Stanton, JM Jarosz, S Landau, DK Jones, GJ Barker, SCR Williams, PN Leigh, A Simmons, A longitudinal study of diffusion tensor imaging (DTI) in ALS, Amyotrophic Lateral Sclerosis and Related Disorders, 8, 348-355, 2007 (Pubmed) MC Craig, EM Daly, R O’Gorman, A Simmons, J Rymer, PM Maki, DG Murphy, Effects of acute ovarian hormone suppression on the human brain : An in vivo 1H MRS study, Neuroenocrinology, 32, 1128-1132, 2007 (Pubmed) S Frangou, M Lewis, J Woolard, A Simmons, Preliminary in vivo evidence of increased N-acetyl-aspartate following eicosapentanoic acid treatment in patients with Bipolar disease, J Psychopharmacol, 21(4), 435-9, 2007 (Pubmed) 2006 R Halari, A Simmons, C Andrew, T Sharma, M Hines, V Kumari, Comparable fMRI activity with differential behavioural performance on mental rotation and overt verbal fluency tasks in healthy men and women, Experimental Brain Research, 169(1), 1-14, 2006(Pubmed) DJ Jones, M Catani, C Pierpaoli, SJC Reeves, SS Shergill, M O’Sullivan, JD Malley, P McGuire, MA Horsfield, A Simmons, SCR Williams, RJ Howard, Age effects on diffusion tensor magnetic resonance imaging tractography measures of frontal cortex connections in schizophrenia, Human Brain Mapping, 27(3), 230-8, 2006 (Pubmed) WJ Cutter, DMW Robertson, EM Daly, XA Chitnis, TAMJ van Amelsvoort, A Simmons, G Ng, S Williams, P Shaw, AS David, GS Conway, DH Skuse, DA Collier, DGM Murphy, X chromosome effects on the human brain : an MRI and MRS study of Turner’s syndrome, Biological Psychiatry, 59(3), 273-283, 2006 (Pubmed) E Lemche, V Giampietro, SA Surguladze, EJ Amaro, C Andrew, SCR Williams, MJ Brammer, N Lawrence, MA Maier, TA Russell, A Simmons, C Ecker, P Joraschky, ML Philips, Human attachment security is mediated by the amygdala : evidence from combined fMRI and psychophysiological measures, Human Brain Mapping, 27(8), 623-635, 2006 (Pubmed) LA Page, E Daly, N Schmitz, A Simmons, F Toal, Q Deeley, F Ambery, G McAlanon, K Murphy, DGM Murphy, An in vivo 1H Magnetic Resonance spectroscopy study of amygdala-hippocampal and parietal regions in autism, Am J Psych, 163(12), 2189-92, 2006 (Pubmed) CRV Blain, GJ Barker, JM Jarosz, NA Coyple, RG Brown, KR Chaudhuri, A Simmons, DK Jones, SCR Williams, PN Leigh, Measuring brain stem and cerebellar systems damage in parkinsonian syndromes using diffusion tensor MRI, Neurology, 67(12), 2199-205, 2006 (Pubmed) 2005 S Abrahams, LH Goldstein, J Suckling, V Ng, A Simmons, X Chitnis, L Atkins, SCR Williams, PN Leigh, Fronto-temporal white matter changes in amyotrophic lateral sclerosis, J Neurology, 252(3), 321-331, 2005 (Pubmed) S Tabakov, VC Roberts, B-A Jonsson, M Ljungberg, CA Lewis, R Wirestam, S-E Strand, I-L Lamm, F Milano, A Simmons, C Deane, D Goss, V Aitken, A Noel, J-Y Giraud, S Sherriff, P Smith, G Clarke, M Almqvist, T Jansson, Development of educational image databases and e-books for medical physics training, Med Eng Phys, 27(7), 591-598, 2005 (Pubmed) DK Jones, M Catani, C Pierpaoloi, SJC Reeves, SS Shergill, MO’Sullivan, JD Malley, P McGuire, MA Horsfield, A Simmons, SCR Williams, RJ Howard, A diffusion tensor magnetic resonance imaging study of frontal cortex connections in very late-onset schizophrenia-like psychosis, Am J Geriatric Psychiatry, 13(12), 1092-9, 2005 (Pubmed) F Beacher, A Simmons, V Prasher, C Adams, E Daly, ML Margallo-Lana, R Morris, S Lovestone, K Murphy, D Murphy, Hippocampal myo-Inositol and cognitive ability in adults with Down syndrome : an in vivo 1H-MRS study, Arch Gen Psychiatry, 62(12), 1360-1365, 2005 (Pubmed) 2004 TM Rushe, CM Temple, L Rifkin, PWR Woodruff, ET Bullmore, A Simmons, T Russell, RM Murray, Lateralisation of language function in young adults born very preterm, Arch Dis Child Fetal Neonatal Ed, 89(2), F112-F118, 2004 (Pubmed) SG Coleshill, CD Binnie, RG Morris, G Alarcon, W van Emde Boas, DN Velis, A Simmons, CE Polkey, CWM Van Veelen, PC van Rijen, Material-specific recognition memory defecits elicted by unilateral hippocampal electrical stimulation, J Neuroscience, 24(7), 1612-6, 2004 (Pubmed) Z Ellison, I Heyman, I Frampton, K Rubia, X Chitnis, I Wright, SCR Williams, A Simmons, E Bullmore, Heterozygous PAX6 mutation, adult brain structure and fronto-striato-thalamic function in a human family, Eur J Neuroscience, 19, 1505-1512, 2004 (Pubmed) N Blackwood, RP Bentall, D ffytche, A Simmons, R Murray, R Howard, Persecutory delusions and the determination of self relevance : an fMRI study, Psychological Medicine, 34, 591-596, 2004 (Pubmed) S Abrahams, L Goldstein, A Simmons, M Brammer, SCR Williams, V Giampietro, PN Leigh, Word retrieval in amyotrophic lateral sclerosis : a functional magnetic resonance imaging study, Brain, 127, 1507-1517, 2004 (Pubmed) DM Parslow, FD Rose, B Brooks, S Fleminger. JA Gray, V Giampietro, MJ Brammer, SCR Williams, D Gasston, C Andrew, GN Vythelingum, G Ioannou, A Simmons, RG Morris, Allocentric spatial memory activation of the hippocampal formation measured using fMRI, Neuropsychology, 18(3), 450-461, 2004 (Pubmed) N Blackwood, RP Bentall, D ffytche, A Simmons, RM Murray, R Howard, The cerebellum and decision making under uncertainty, Cognitive Brain Research, 20, 46-53, 2004 (Pubmed) PJ Monks, JM Thompson, ET Bullmore, J Suckling, MJ Brammer, SCR Williams, A Simmons, N Giles, AJ Lloyd, C Louise Harrison, M Seal, RM Murray, I Nicol Ferrier, AH Young, V Curtis, A functional MRI study of working memory task in euthymic bipolar disorder : evidence for task specific dysfunction, Bipolar Disord, 6(6), 550-64, 2004 (Pubmed) 2003 V Kumari, MT Mitterschiffthaler, JD Teasdale, GS Malhi, RG Brown, V Giampietro, MJ Brammer, L Poon, A Simmons, SCR Williams, SA Checkley, T Sharma, Neural abnormalities during cognitive generation of affect in treatment resistant depression, Biological Psychiatry, 54(8), 777-791, Oct 2003 (Pubmed) V Kumari, JA Gray, MA Geyer, D ffytche, W Soni, MT Mitterschiffthaler, GN Vythelingum, A Simmons, SCR Williams, T Sharma, Neural correlates of tactile prepulse inhibition : a functional MRI study in normal and schizophrenic subjects, Psychiatry Research, 99-112, 122(2), 2003 (Pubmed) T Sigmundsson, M Maier, BK Toone, SCR Williams, A Simmons, K Greenwood, MA Ron, Frontal lobe N-acetylaspartate correlates with psychopathology in schizophrenia : a proton magnetic resonance spectroscopy study, Schizophrenia Research, 64(1), 63-71, 2003 (Pubmed) MT Mitterschiffthaler, V Kumari, GS Malhi, RG Brown, VP Giampietro, MJ Brammer, J Suckling, L Poon, A Simmons, C Andrew, T Sharma, Neural response to pleasant stimuli in anhedonia : a functional magnetic resonance imaging study, Neuroreport, 14(2), 177-82, 2003 (Pubmed) V Kumari, JA Gray, D Ffytche, MT Mitterschiffthaler, M Das, E Zachariah, GN Vythelingum, SCR Williams, A Simmons, TE Goldberg, T Sharma, Cognitive effects of nicotine in humans : an fMRI study, Neuroimage, 19(3), 1002-1013, 2003 (Pubmed) D Fannon, A Simmons, L Tennakoon, S O’Ceallaigh, A Sumich, V Doku, C Shew, T Sharma, Selective defecit of hippocampal N-acetylaspartate in antipsychotic naïve patients with schizophrenia, Biological Psychiatry, 54(6), 587-598, 2003 (Pubmed) NJ Blackwood, RP Bentall, D ffytche, A Simmons, RM Murray, RJ Howard, Self-responsibility and the self-serving bias: an fMRI investigation of causal attributions, Neuroimage, 20(2), 1076-1085, 2003 (Pubmed) S Abrahams, LH Goldstein, A Simmons, M Brammer, CN Andrew, PN Leigh, SCR Williams, Functional magnetic resonance imaging of verbal fluency and confrontation naming using compressed image acquisition to permit overt responses, Human Brain Mapping, 20(1), 29-40, 2003 (Pubmed) 2002 DK Jones, SCR Williams, D Gasston, MA Horsfield, A Simmons, R Howard, Isotropic resolution diffusion tensor imaging with whole brain acquisition in a clinically acceptable time, Human Brain Mapping, 15(4), 216-230, 2002 (Pubmed) V Kumari, J Gray, G Honey, W Soni, E Bullmore, S Williams, G Vythelingum, A Simmons, P Corr, T Sharma, Procedural learning in schizophrenia : a functional magnetic resonance imaging investigation, Schizophrenia Research, 57(1), 97 - , 2002 (Pubmed) T Kircher, M Brammer, E Bullmore, A Simmons, M Bartels, AS David, The neural correlates of intentional and incidental self processing, Neuropsychologia, 40, 683-692, 2002 (Pubmed) M MacSweeney, B Woll, R Campbell, GA Calvert, PK McGuire, AS David, A Simmons, MJ Brammer, Neural correlates of British Sign Language processing : specific regions for topographic language, J Cog Neuroscience, 14(7), 1064-1075, 2002 (Pubmed) GM McAlonan, E Daly, V Kumari, HD Critchley, T van Amelsvoort, J Suckling, A Simmons, T Sigmundsson, K Greenwood, A Russell, F Happe, P Howlin, DG Murphy, Brain anatomy and sensorimotor gating in Asperger’s syndrome, Brain, 127, 1594-1606, 2002 (Pubmed) J Shapleske, SL Rossell, X Chitnis, J Suckling, A Simmons, ET Bullmore, P Woodruff, AS David, A computational morphometric MRI study of schizophrenia : effects of hallucinations, Cerebral Cortex, 12(12), 1331-1341, 2002 (Pubmed) DG Murphy, HD Critchley, N Schmitz, G McAlanon, T van Amelsvoort, D Robertson, E Daly, A Rowe, A Russell, A Simmons, KC Murphy, P Howlin, Asperger syndrome – a proton magnetic resonance spectroscopy study of brain, Arch Gen Psychiatry, 59(10), 885-91, 2002 (Pubmed) PN Leigh, A Simmons, S Williams, V Williams, M Turner, D Brooks, Imaging : MRS / MRI / PET / SPECT, Amyotroph Lateral Scler Other Motor Neuron Disord, 3 Suppl 1(2), 75-80, 2002 (Pubmed) SL Rossell, J Shapleske, R Fukuda, PWR Woodruff, A Simmons, AS David, Corpus callosum area and functioning in patients with auditory-verbal hallucinations, Schizophrenia Research, 50(1-2), 9-17, 2001 (Pubmed) TT Kircher, C Senior, ML Phillips, S Rabe-Hesketh, PJ Benson, ET Bullmore, M Brammer, A Simmons, M Bartels, AS David, Recognising one’s own face, Cognition, 78(1), B1-B15, 2001 (Pubmed) J Shapleske, SL Rossell, PWR Woodruff, A Simmons, AS David, Are auditory hallucinations the consequences of abnormal cerebral lateralisation ? A morphometric MRI study of the Sylvian fissure and planum temporale, Biological Psychiatry, 49(8), 685-693, 2001 (Pubmed) K Rubia, S Overmeyer, T Russel, T Sharma, M Brammer, E Bullmore, A Simmons, SCR Williams,. CM Andrews, E Taylor, Mapping motor response inhibition : generic brain activation across different versions of go-no-go and stop tasks, Neuroimage, 13(2), 250-261, 2001 (Pubmed) D Lythgoe, A Simmons, A Perreira, M Cullinane, V Doyle, S Williams,. H Markus, Magnetic resonance markers of ischemia : their correlation with vasodilatory reserve in patients with carotid artery stenosis and occlusion, J Neurol Neurosurg Psychiatry 71(1), 58-62, 2001 (Pubmed) JM Rosenthal, SA Amiel, L Yaguez, E Bullmore, D Hopkins, M Evans, A Pernet, H Reid, V Giampietro, CM Andrew, J Suckling, A Simmons, SCR Williams, The effect of acute hypoglycemia on brain function and activation – an functional magnetic resonance imaging study, Diabetes, 50(7), 1618-1626, 2001 (Pubmed) SE Connor, R O’Gorman, P Summers, A Simmons, EM Moore, C Chandler, JM Jarosz, SPAMM, cine phase contrast imaging and fast spin echo T2-weighted imaging in the study of intracranial cerebrospinal fluid (CSF) flow, Clinical Radiology, 56(9), 763-772, 2001 (Pubmed) H Matsumoto, A Simmons, S Williams, R Pipe, R Murray, S Frangou, Structural magnetic resonance imaging of the hippocampus in early onset schizophrenia, Biological Psychiatry, 49(10), 824-831, 2001 (Pubmed) S Overmeyer, ET Bullmore, J Suckling, A Simmons, SCR Williams, PJ Santosh, E Taylor, Distributed grey and white matter deficits in hyperkinetic disorder : MRI evidence for anatomic abnormality in an attentional network, Psychological Medicine, 31(8), 1425-35, 2001 (Pubmed) CM Ellis, J Sucklingm E Amaro Jr, ET Bullmore, A Simmons, SCR Williams, PN Leigh, Volumetric analysis reveals corticospinal tract degeneration and extra-motor involvement in ALS, Neurology, 57(9), 1571-8, 2001 (Pubmed) SE Rose, JB Chalk, M Griffin, AL Janke, F Chen, GJ McLachan, D Peel, FO Zelaya, A Simmons, HS Markus, W Strugnell, DM Doddrell, J Semple, MRI based diffusion and perfusion predictive model to estimate stroke evolution, Magn Reson Im, 19(8), 1043-53, 2001 (Pubmed) H Matsumoto, A Simmons, SCR Williams, M Hadjulis, R Pipe, R Murray, S Frangou, Superior temporal gyrus abnormalities in early onset schizophrenia : similarities and differences with adult-onset schizophrenia, Am J Psych, 158(8), 1299-304, 2001 (Pubmed) C Steel, EJ Haworth, E Peters, DR Hemsley, T Sharma, JA Gray, A Pickering, L Gregory, A Simmons, ET Bullmore, SCR Williams, Neuroimaging correlates of negative priming, Neuroreport, 12, 3619-3624, 2001 (Pubmed) K Rubia, T Russell, ET Bullmore, W Soni, MJ Brammer, A Simmons, E Taylor, C Andrew, V Giampietro, T Sharma, An fMRI study of reduced left prefrontal activation in schizophrenia during normal inhibitory function, Schizophrenia Research, 52(1-2), 47-55, 2001(Pubmed) DMW Robertson, T van Amelsvoort, E Daly, A Simmons, M Whitehead, RG Morris, KC Murphy, DGM Murphy, Effects of estrogen replacement therapy on human brain ageing : an in vivo 1H MRS study, Neurology, 57, 2114-2117, 2001 (Pubmed) K Rubia, S Overmeyer, E Taylor, M Brammer, SCR Williams, A Simmons, E Bullmore, Functional frontalisation with age : mapping neurodevelopmental trajectories with fMRI, Neuroscience Behavioural Review, 24(1), 13-19, 2000 (Pubmed) S Overmeyer, A Simmons, PJ Santosh, A Simmons, C Andrew, SCR Williams, W Chen, E Taylor, Corpus callosum may be similar in children with ADHD and controls, Developmental medicine and child neurology, 42(1), 8-13, 2000 (Pubmed) DJ Lythgoe, L Ostergaard, SCR Williams, A Cluckie, M Buxton-Thomas, A Simmons, HS Markus, Quantitative perfusion imaging in carotid artery stenosis using dynamic susceptibility contrast enhanced magnetic resonance imaging, Magnetic Resonance Imaging, 18(1), 1-11, 2000 (Pubmed) HD Critchley, A Simmons, EM Daley, T van Amelsvoort, DM Robertson, A Glover, DGM Murphy, Prefrontal and medial temporal correlates of repetitive violence to self and others, Biological Psychiatry, 47(10), 928-934, 2000 (Pubmed) CM Ellis, A Simmons, A Glover, JM Dawson, SCR Williams, PN Leigh, Assessing neuronal integrity in amyotrophic lateral sclerosis using proton magnetic resonance spectroscopy : absolute metabolite concentrations, ALS and Other Motor Neurone Disorders, 1, 123-129, 2000 (Pubmed) C Senior, J Barnes, V Giampietro, A Simmons, E Bullmore, M Brammer, A David, The functional neuroanatomy of implicit motion perception or ‘Representational Momentum’, Current Biology, 10(1), 16-22, 2000 (Pubmed) R Bruening, C Berchtenbreiter, N Holzknecht, M Essig, RH Wu, A Simmons, A Heuck, A Maschek, M Meusel, SCR Williams, TS Cox, M Knopp, M Reiser, Effects of three different doses of a bolus injection of gadodiamide : assessment of rCBV maps in a blinded reader study, AJNR,21(9), 1603-1610, 2000 (Pubmed) DLG Hill, AD Castellano Smith, A Simmons, CR Maurer Jr, TCS Cox, R Elwes, MJ Brammer, DJ Hawkes, CE Polkey, Sources of error in comparing functional magnetic resonance imaging and invasive electrophysiology recordings, J Neurosurgery, 93(2), 214-223, 2000 (Pubmed) N Blackwood, R Howard, D Ffytche, A Simmons, R Bentall, R Murray, Imaging attentional and attributional bias : an fMRI approach to the paranoid delusion, Psychological Medicine, 30(4), 873-883, 2000 (Pubmed) SS Shergill, E Bullmore, A Simmons, RM Murray, PK McGuire, The functional anatomy of auditory verbal imagery in patients with auditory hallucinations, American Journal of Psychiatry, 157(10), 1691-3, 2000 (Pubmed) Q Aziz, DG Thompson, VWK Ng, S Hamdy, S Sarkar, MJ Brammer, ET Bullmore, A Hobson, I Tracy, A Simmons, SCR Williams, Processing of somatic and visceral sensation by the human cerebral cortex, J Neuroscience, 20(7), 2657-2663, 2000 (Pubmed) TA Russell, K Rubia, E Bullmore, W Soni, J Suckling, M Brammer, A Simmons, SCR Williams, T Sharma, Exploring the social brain in schizophrenia : left prefrontal underactivation during mental state attribution, Am J Psych, 157(12), 2040-2041, 2000 (Pubmed) TTJ Kircher, C Senior, ML Philips, PJ Benson, ET Bullmore, M Brammer, A Simmons, SC Williams, M Bartels, AS David, Towards a functional neuroanatomy of self processing : effects of faces and words, Brain Res Cogn Brain Res, 10, 133-144, 2000 (Pubmed) J Barnes, RJ Howard, C Senior, M Brammer, ET Bullmore, A Simmons, P Woodruff, AS David, Cortical activity during rotational and linear transformations, Neuropsychologia, 38(8), 1148-1156, 2000 (Pubmed) CH Ferrier, G Alacon, M Koutroumanidis, RG Morris, A Simmons, A Glover, R Elwes, CD Binnie, CE Polkey, N-acetylaspartate and creatine measured by 1H MRS relates to recognition memory, Neurology, 55, 1874-1883, 2000 (Pubmed) DK Jones, R Dardis, M Ervine, MA Horsfield, M Jeffree, A Simmons, J Jarosz, AJ Strong, Cluster analysis of diffusion tensor magnetic resonance images in head injury, Neurosurgery, 47(2), 306-313, 2000 (Pubmed) CM Ellis, N Adams, D Bridgen, A Simmons, G Lemmens, SCR Williams, JD Parkes, Functional echoplanar brain imaging in normal subjects and subjects with the narcoleptic syndrome. Action of modafinil, J Sleep Research, 8(2), 85-93, 1999 (Pubmed) DK Jones, D Lythgoe, MA Horsfield, A Simmons, SCR Williams, HS Markus, Characterisation of white matter damage in ischaemic leukoaraiosis with diffusion tensor MRI, Stroke, 30(2), 393-397, 1999 (Pubmed) K Rubia, S Overmeyer, E Taylor, M Brammer, SCR Williams, A Simmons, E Bullmore, Hypofrontality in Attention Deficit Hyperactivity Disorder (ADHD) during higher order motor control : a study with fMRI, Am J Psych, 156(6), 891-6, 1999 (Pubmed) A Simmons, E Moore, SCR Williams, Quality control for functional MRI using automated data analysis and Shewhart charting, Magnetic Resonance in Medicine, 41, 1274-1278, 1999 (Pubmed) VA Curtis, ET Bullmore, RG Morris, MJ Brammer, SCR Williams, T Sharma, A Simmons, RM Murray, PK McGuire, Attenuated frontal activation in schizophrenia may be task dependent, Schizophrenia Research, 37(1), 35-44, 1999 (Pubmed) A Simmons, DK Jones, MA Horsfield, SCR Williams, The application of diffusion tensor MRI to neurological segmentation, International Journal of Imaging Science and Technology, 10, 273-286, 1999 (Pubmed) S Baron-Cohen, HA Ring, S Wheelwright, ET Bullmore, MJ Brammer, A Simmons, SCR Williams, Social intelligence in the normal and autistic brain : an fMRI study, Eur J Neurosci, 11(6), 1891-1898, 1999 (Pubmed) DK Jones, A Simmons, SCR Williams, MA Horsfield, Non-invasive assessment of axonal fibre connectivity in the human brain via diffusion tensor MRI, Magnetic Resonance in Medicine, 42(1), 37-41, 1999 (Pubmed) J Barnes, C Senior, M Brammer, ET Bullmore, RJ Howard, A Simmons, AS David, The functional anatomy of the McCollough contingent colour after-effect, Neuroreport, 10, 195-199, 1999 (Pubmed) DK Jones, MA Horsfield, A Simmons, Optimal strategies for measuring diffusion in anisotropic systems by magnetic resonance imaging, Magnetic Resonance in Medicine, 42(3), 515-525, 1999 (Pubmed) CM Ellis, A Simmons, DK Jones, J Bland, JM Dawson, M Horsfield, SCR Williams, PN Leigh, The use of diffusion tensor MRI in Amyotrophic Lateral Sclerosis, Neurology, 53(5), 1051-8, 1999 (Pubmed) CM Ellis, A Simmons, J Dawson, SCR Williams, PM Leigh, Distinct hyperintense MRI signal changes in the motor region of a patient with motor neuron disease, ALS and Other Motor Neurone Disorders, 1, 41-44, 1999 (Pubmed) G.J. Barker, A. Simmons, P.S. Tofts, S.R. Arridge, A simple method for separating the effects on non-uniformity of RF transmission from those of RF reception, British Journal of Radiology, 71, 59-67, 1998 (Pubmed) JL Barbur, A Sahraie, A Simmons, L Weiskrantz, SCR Williams, Processing of chromatic signals in the absence of a geniculostriate projection, Vision Research, 38, 3347-3353, 1998 (Pubmed) C Andrews, A Simmons, SCR Williams, Magnetic resonance imaging and spectroscopy, in press, Physics Update, 1997 CM Ellis, A Simmons, G Lemmens, SCR Williams, JD Parkes, Proton magnetic resonance spectroscopy in the narcoleptic syndrome : is there evidence of a brainstem lesion ?, Neurology, 50(2 Suppl 1), S23-S26, 1998 (Pubmed) A Simmons, M Smail, E Moore, SCR Williams, Serial precision of metabolite peak area ratios and water referenced metabolite peak areas in proton MR spectroscopy of the human brain, Magnetic Resonance Imaging, 16(3), 319-330, 1998 (Pubmed) GI de Zubicaray, SJ Wilson, SE Rose, SCR Williams, MJ Brammer, ET Bullmore, A Simmons, JB Chalk, J Semple, GA Smith, R Ashton, DM Doddrell, Prefrontal cortex involvement in selective letter generation : a functional magnetic resonance imaging study, Cortex, 34(3), 389-402, 1998 (Pubmed) RJ Howard, J Barnes, DH Ffytche, D McKeefry, Y Ha, PW Woodruff, M Brammer, ET Bullmore, A Simmons, AS David, The functional anatomy of imagining and perceiving colour, Neuroreport, 9, 1019-1023, 1998 (Pubmed) A. Simmons, S.R. Arridge, P.S. Tofts, G.J. Barker, Application of the stack to neurological MRI, IEEE Transactions on Medical Imaging, 17(3), 371-382, 1998 (Pubmed) K Rubia, S Overmeyer, E Taylor, M Brammer, SCR Williams, A Simmons, C Andrew, E Bullmore, Prefrontal involvement in temporal bridging and timing movement, Neuropsychologia, 26(12), 1283-1293, 1998 (Pubmed) ML Phillips, E Bullmore, R Howard, PWR Woodruff, I Wright, SCR Williams, A Simmons, C Andrew, M Brammer, AS David, Investigation of facial recognition memory and happy and sad facial expression perception : an fMRI study, Psychiatry Res, 83(3), 127-38, 1998 (Pubmed) CM Ellis, A Simmons, C Andrews, J Dawson, SCR Williams, PN Leigh, The assessment of neuronal loss in ALS using proton magnetic resonance spectroscopy : correlation with clinical findings, Neurology, 51(4), 1104-9, 1998 (Pubmed) ZR Ellison, J Foong, R Howard, ET Bullmore, MJ Brammer, SCR Williams, C Andrew, A Simmons, J Treasure, Functional anatomy of calorie fear in anorexia nervosa, in press, Lancet (Pubmed) M Samuel, SCR Williams, PN Leigh, A Simmons, C Andrew, S Chakraborti, LH Goldstein, DJ Brooks, Exploring the temporal nature of haemodynamic responses of cortical motor areas using functional MRI, Neurology, 51(6), 1567-1575, 1998 (Pubmed) A Simmons, DE Simpson, S Barrington, MJ O’Doherty, AJ Coakley, The effects of standardisation and reference values on patient classification for spine and femur DXA, Osteoporosis International, 7, 200-206, 1997 A. Simmons, S.C.R. Williams, M. Craggs, C. Andrew, L. Lynch, M. Allin, A. Mundy, J. Bellringer, B. Leaker, Dynamic echo planar imaging of the urinary bladder during voiding, Magnetic Resonance Imaging, 15(3), 295-300, 1997 CM Ellis, G Lemmens, SCR Williams, A Simmons, J Dawson, PN Leigh, K Ray Chaudhuri, Changes in putamen N-acetylaspartate and choline ratios in untreated and levadopa treated Parkinson’s disease : a proton magnetic resonance spectroscopy study, Neurology, 49(2), 438-444, 1997 MJ Brammer, ET Bullmore, A Simmons, SCR Williams, PM Grasby, RJ Howard, PWR Woodruff, S Rabe-Hesketh, Generic brain activation mapping in fMRI : a non-parametric approach, Magnetic Resonance Imaging, 15(7), 763-770, 1997 G Busatto, RJ Howard, Y Ha, M Brammer, I Wright, PWR Woodruff, A Simmons, SCR Williams, AS David, ET Bullmore, A functional magnetic resonance imaging study of episodic memory, Neuroreport, 8, 2671-2675, 1997 DM Yousem, SCR Williams, RO Howard, C Andrew, A Simmons, M Allin, RJ Geckle, D Suskind, ET Bullmore, MJ Brammer, RL Doty, Functional MRI during odor stimulation : normative data, Radiology, 204(1), 833-838, 1997 A Sahraie, L Weiskrantz, JL Barbur, A Simmons, SCR Williams, MJ Brammer, Pattern of neuronal activity under conscious and unconscious processing of visual signals, Proceedings of the National Academy of Sciences, 94, 9406-9411, 1997 (Pubmed) L Sell, A Simmons, GM Lemmens, SCR Williams, J Strang, Functional magnetic resonance imaging of the acute effect of intravenous heroin on visual activation in long term heroin addicts : results from a feasibility study, Drug and Alcohol Dependence, 49, 55-60, 1997 Y-L Chung, EC Smith, SCR Williams, WS Wassif, J Salisbury, A Simmons, DC Howlett, DL Scott, In vivo proton magnetic resonance spectroscopy in polymyositis and dermatomyositis : a preliminary study, Eur J Medicine, 2(11), 483-487, 1997 A. Simmons, S.R. Arridge, G.J. Barker, S.C.R. Williams, Simulation of MRI cluster plots and application to neurological segmentation, Magnetic Resonance Imaging, 14(1), 73-92, 1996 A. Simmons, S. Barrington, L.J. Archbold, M.J. O’ Doherty, A.J. Coakley, Assessment of changes in DXA performance following a system upgrade, Nuclear Medicine Communications, 17(4), 331-341, 1996 C. Andrews, A. Simmons, S.C.R. Williams, Magnetic resonance imaging and spectroscopy, Physics Education, 31(2), 80-85, 1996 K.R. Chaudhuri, G. Lemmens, S.C.R. Williams, C. Ellis, C.M. Lloyd, J. Dawson, A. Simmons, P.N. Leigh, Proton magnetic resonance spectroscopy of the striatum in Parkinson’s disease patients with motor response fluctuations, Parkinsonism and Related Disorders, 2(2), 63-67, 1996 C Ellis, RJ Howard, ET Bullmore, M Brammer, JD Mellers, PW Woodruff, AS David, A Simmons, SC Williams, JD Parkes, Functional echoplanar brain imaging correlates of amphetamine administration to normal subjects and subjects with the narcoleptic syndrome, Magnetic Resonance Imaging, 14(9), 1013-1016, 1996 A. Simmons, S. Barrington, M.J. O’Doherty, A.J. Coakley, Dual energy X-ray absorptiometry normal reference range use within the UK and the effect of different normal ranges on the assessment of bone density, British Journal of Radiology, 68(8), 903-909, 1995 E. Bullmore, M. Brammer, G. Rouleau, B. Everitt, A. Simmons, T. Sharma, S. Frangou, R. Murray, G. Dunn, Computerised brain tissue classification of magnetic resonance images : a new approach to the problem of partial volume artifact, NeuroImage, 2, 133-147, 1995 R.J. Howard, E. Bullmore, M. Brammer, S.C.R. Williams, J. Mellers, A. David, P. Woodruff, C. Andrew, M. Allin, A. Simmons, T. Cox, Activation of area V5 by visual perception of motion demonstrated with Echoplanar MR imaging, Magnetic Resonance Imaging, 13(6), 907-909, 1995 A. Simmons, S. Barrington, M.J. O’ Doherty, A.J. Coakley, A survey of dual-energy X-ray absorptiometry normal reference ranges used within the United Kingdom and their effect on patient classification, Nuclear Medicine Communications, 16(12), 1041-1053, 1995 JDC Mellers, E Bullmore, M Brammer, SCR Williams, C Andrew, N Sachs, C Andrews, TS Cox, A Simmons, P Woodruff, AS David, R Howard, Neural correlates of verbal working memory : a functional magnetic resonance imaging study, Neuroreport, 7(1), 109-112, 1995 A. Simmons, P.S. Tofts, G.J. Barker, S.R. Arridge, Sources of intensity non-uniformity in spin echo images at 1.5 T, Magnetic Resonance in Medicine, 32(1), 121-128, 1994 A. Simmons, G.J. Barker, P.S. Tofts, A. Gass, S.R. Arridge, A method for visualisation of MRI partial volume regions - PAIR (PArtial volume sensitised Inversion Recovery imaging), Magnetic Resonance Imaging, 12(5), 821-826, 1994 A. Simmons, S.R. Arridge, G.J. Barker, A.J. Cluckie, P.S. Tofts, Improvements to the quality of MRI cluster analysis, Magnetic Resonance Imaging, 12(8), 1191-1204, 1994 P.S. Tofts, G.J. Barker, A. Simmons, D.G. MacManus, J. Thorpe, A. Gass, D.H. Miller, Correction of Non-Uniformity in Images of the Spine and Optic Nerve from Fixed Receive-Only Surface Coils at 1.5 T, Journal of Computer Assisted Tomography, 18(6), 997-1003, 1994 Publications
| Collaborators
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Detail Information
Publications
Magnetic resonance safetyAndrew Simmons
King s College London, Institute of Psychiatry, Centre for Neuroimaging Sciences, London, UK
Methods Mol Biol 711:17-28. 2011..Finally, contrast agents, auditory effects and medical implants and devices are discussed, as well as the less thought about issue of biological safety of clinical and pre-clinical MR systems...
Effects of acute ovarian hormone suppression on the human brain: an in vivo 1H MRS studyMichael C Craig
Department of Psychological Medicine, Institute of Psychiatry, Section of Brain Maturation, London, UK
Psychoneuroendocrinology 32:1128-32. 2007..They also showed a trend to a significant increase in Cho concentration in the hippocampus. This supports our previous findings and adds to the evidence that neuronal/glial membrane metabolism is affected by sex hormones in women...
Altered cortical activation during a motor task in ALS. Evidence for involvement of central pathwaysBiba R Stanton
Dept of Clinical Neuroscience, MRC Centre for Neurodegeneration Research, Institute of Psychiatry, King s College London, De Crespigny Park, London SE5 8AF, UK
J Neurol 254:1260-7. 2007..To test the hypothesis that patients with amyotrophic lateral sclerosis (ALS) show increased cortical activation during a motor task compared to both healthy controls and patients with muscle weakness due to peripheral lesions...
In vivo 1H-magnetic resonance spectroscopy study of amygdala-hippocampal and parietal regions in autismLisa A Page
Section of Brain Maturation, Institute of Psychiatry, London
Am J Psychiatry 163:2189-92. 2006..CONCLUSIONS: Abnormalities in glutamate/glutamine may partially underpin the pathophysiology of autistic spectrum disorders, and the authors confirm earlier reports that limbic areas are metabolically aberrant in these disorders...
A diffusion tensor magnetic resonance imaging study of frontal cortex connections in very-late-onset schizophrenia-like psychosisDerek K Jones
Section on Tissue Biophysics and Biomimetics, National Institute of Child Health and Human Development/NIH, Bethesda, MD 20892, USA
Am J Geriatr Psychiatry 13:1092-9. 2005....
Human attachment security is mediated by the amygdala: evidence from combined fMRI and psychophysiological measuresErwin Lemche
Division of Psychological Medicine, Section of Neuroscience and Emotion, Institute of Psychiatry, London, United Kingdom
Hum Brain Mapp 27:623-35. 2006..We thereby demonstrate a key role of the amygdala in mediating autonomic activity associated with human attachment insecurity...
Comparable fMRI activity with differential behavioural performance on mental rotation and overt verbal fluency tasks in healthy men and womenRozmin Halari
Centre for Social, Genetic and Developmental Psychiatry, Institute of Psychiatry, De Crespigny Park, P O Box 46, London SE5 8AF, UK
Exp Brain Res 169:1-14. 2006..Our results demonstrate comparable brain activation in men and women in association with mental rotation and verbal fluency function with differential performance, and provide support for sex differences in brain-behaviour relationships...
Age effects on diffusion tensor magnetic resonance imaging tractography measures of frontal cortex connections in schizophreniaDerek K Jones
Section on Tissue Biophysics and Biomimetics, LIMB, NICHD, National Institutes of Health, Bethesda, Maryland, USA
Hum Brain Mapp 27:230-8. 2006....
Development of educational image databases and e-books for medical physics trainingS Tabakov
Med Eng Phys 27:591-8. 2005..Both the e-books and IDB are engraved on five separate CD-ROMs. Demo of these materials can be taken from www.emerald2.net...
A functional MRI study of working memory task in euthymic bipolar disorder: evidence for task-specific dysfunctionPaul J Monks
Division of Psychological Medicine, Institute of Psychiatry, London, UK
Bipolar Disord 6:550-64. 2004..CONCLUSIONS: Our findings support the notion that, in euthymic bipolar disorder, failure to engage fronto-executive function underpins the core neuropsychological deficits...
Word retrieval in amyotrophic lateral sclerosis: a functional magnetic resonance imaging studyS Abrahams
Department of Psychology, Institute of Psychiatry, King s College, London, UK
Brain 127:1507-17. 2004..This study provides evidence of cerebral abnormalities in ALS in the network of regions involved in language and executive functions. Moreover, the findings further illustrate the heterogeneity of cognitive and cerebral change in ALS...
The cerebellum and decision making under uncertaintyNigel Blackwood
Division of Psychological Medicine, Institute of Psychiatry, PO Box 70, De Crespigny Park, London SE5 8AZ, UK
Brain Res Cogn Brain Res 20:46-53. 2004..We hypothesise that the neo-cerebellum constructs internal working models of uncertain events in the external world, and that such probabilistic models subserve the predictive capacity central to induction...
Cortical activation during motor imagery is reduced in Amyotrophic Lateral SclerosisBiba R Stanton
MRC Centre for Neurodegeneration Research and Department of Clinical Neuroscience, King s College London, Institute of Psychiatry PO41, De Crespigny Park, London, UK
Brain Res 1172:145-51. 2007..This reduction in cortical activation during motor imagery contrasts with the pattern seen during motor execution. This may represent the disruption of normal motor imagery networks by ALS pathology outside the primary motor cortex...
Association between a longer duration of illness, age and lower frontal lobe grey matter volume in schizophreniaPreethi Premkumar
Department of Psychology, Institute of Psychiatry, De Crespigny Park, King s College London, London SE5 8AF, United Kingdom
Behav Brain Res 193:132-9. 2008..The effect of illness chronicity on GM volume in the left dorsomedial PFC may be extended to brain structure-neuropsychological function relationships...
Alzheimer's disease and Down's syndrome: an in vivo MRI studyF Beacher
Institute of Psychiatry, King s College, London, UK
Psychol Med 39:675-84. 2009..Individuals with Down's syndrome (DS) are at high risk of developing Alzheimer's disease (AD). However, few studies have investigated brain anatomy in DS individuals with AD...
A novel white matter fibre tracking algorithm using probabilistic tractography and average curvesNagulan Ratnarajah
Medical Image Computing, School of Biosciences, University of Kent, UK
Med Image Comput Comput Assist Interv 13:666-73. 2010..A new clustering algorithm is employed to separate fibres into branches before applying averaging methods. The performance of the technique is verified on a wide range of seed points using a phantom dataset and an in vivo dataset...
Multivariate analysis of MRI data for Alzheimer's disease, mild cognitive impairment and healthy controlsEric Westman
Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Stockholm, Sweden
Neuroimage 54:1178-87. 2011..Combining the different MRI measures together resulted in a significantly better classification than using them separately. OPLS also shows potential for predicting conversion from MCI to AD...
MRI measures of Alzheimer's disease and the AddNeuroMed studyAndrew Simmons
NIHR Specialist Biomedical Research Centre for Mental Health at the South London and Maudsley NHS Foundation Trust and King s College London and the MRC Centre for Neurodegeneration, King s College London, Institute of Psychiatry, London SE5 8AF, United Kingdom
Ann N Y Acad Sci 1180:47-55. 2009..Measurements of normalized whole brain volume, whole brain cortical thickness, and point-by-point group-based cortical thickness measurements, demonstrating the power of the automated image analysis techniques employed, are reported...
AddNeuroMed--the European collaboration for the discovery of novel biomarkers for Alzheimer's diseaseSimon Lovestone
NIHR Specialist Biomedical Research Centre for Mental Health at the South London and Maudsley NHS Foundation Trust and King s College London, Institute of Psychiatry, London SE5 8AF, United Kingdom
Ann N Y Acad Sci 1180:36-46. 2009..Second, design is paramount and combining modalities, such as imaging and proteomics, may be informative. Third, animal models are valuable in biomarker research. Most importantly, we have learned that plasma markers are feasible...
A modified damped Richardson-Lucy algorithm to reduce isotropic background effects in spherical deconvolutionFlavio Dell'Acqua
CERMAC, San Raffaele Scientific Institute, Milan, Italy
Neuroimage 49:1446-58. 2010..Considering both the speed of processing and the scan time required, this new method has the potential for better characterizing white matter anatomy and the integrity of pathological tissue...
Structural magnetic resonance imaging predictors of responsiveness to cognitive behaviour therapy in psychosisPreethi Premkumar
Department of Psychology, Institute of Psychiatry, King s College London, London, UK
Schizophr Res 115:146-55. 2009..This study aimed to determine whether improvement in symptoms following CBT for psychosis (CBTp) in people with schizophrenia is positively associated with pre-therapy grey matter volume in brain regions involved in cognitive processing...
Brain anatomy and ageing in non-demented adults with Down's syndrome: an in vivo MRI studyF Beacher
Institute of Psychiatry, Kings College, London SE5 8AF, UK
Psychol Med 40:611-9. 2010..People with Down's syndrome (DS) are at high risk for developing dementia in middle age. The biological basis for this is unknown. It has been proposed that non-demented adults with DS may undergo accelerated brain ageing...
Effects of estrogen therapy on age-related differences in gray matter concentrationD Robertson
Department of Psychological Medicine, Institute of Psychiatry, King s College, London, UK
Climacteric 12:301-9. 2009..The inconsistency in the findings of previous studies is likely to be due to a variety of methodological factors. In this study, we attempted to overcome many of these factors...
Proteome-based identification of plasma proteins associated with hippocampal metabolism in early Alzheimer's diseaseMadhav Thambisetty
King s College London, MRC Centre for Neurodegeneration Research, Institute of Psychiatry, De Crespigny Park, Denmark Hill, London SE5 8AF, UK
J Neurol 255:1712-20. 2008..We also undertook a proteomic analysis of plasma in these individuals using two-dimensional gel electrophoresis (2DGE)...
Diffusion tensor imaging in sporadic and familial (D90A SOD1) forms of amyotrophic lateral sclerosisBiba R Stanton
Medical Research Council Centre for Neurodegeneration Research and Department of Clinical Neuroscience, Institute of Psychiatry, King s College London, London SE5 8AF, England
Arch Neurol 66:109-15. 2009..The basis of heterogeneity in the clinical presentation and rate of progression of amyotrophic lateral sclerosis (ALS) is poorly understood...
Cortical grey matter volume and sensorimotor gating in schizophreniaVeena Kumari
Department of Psychology, Institute of Psychiatry, King s College London, London, UK
Cortex 44:1206-14. 2008....
Heterozygous PAX6 mutation, adult brain structure and fronto-striato-thalamic function in a human familyZoë Ellison-Wright
Institute of Psychiatry, King s College London, De Crespigny Park, London SE5 8AF, UK
Eur J Neurosci 19:1505-12. 2004..Highly conserved homeobox genes may be critical for normal ontogenesis of large-scale neurocognitive networks supporting phylogenetically advanced mental functions...
Lateralisation of language function in young adults born very pretermT M Rushe
Department of Psychology, University of Ulster at Jordanstown, N Ireland BT37 0QB, UK
Arch Dis Child Fetal Neonatal Ed 89:F112-8. 2004..To explore, using functional magnetic resonance imaging (MRI), the functional organisation of phonological processing in young adults born very preterm...
Self-responsibility and the self-serving bias: an fMRI investigation of causal attributionsN J Blackwood
Division of Psychological Medicine, Institute of Psychiatry, London, UK
Neuroimage 20:1076-85. 2003..The dorsal striatum, previously implicated in motivated behavior, mediates the self-serving bias...
SPAMM, cine phase contrast imaging and fast spin-echo T2-weighted imaging in the study of intracranial cerebrospinal fluid (CSF) flowS E Connor
Department of Neuroradiology, King's College Hospital, London
Clin Radiol 56:763-72. 2001..CONCLUSION: SPAMM provides a comparable assessment of intracranial CSF flow to that of cine phase contrast imaging at all CSF sites except the cerebral aqueduct...
Superior temporal gyrus abnormalities in early-onset schizophrenia: similarities and differences with adult-onset schizophreniaH Matsumoto
Institute of Psychiatry, Division of Psychological Medicine, Section of Neurobiology of Psychosis, De Crespigny Park, London, SE5 8AF, UK
Am J Psychiatry 158:1299-304. 2001..The relationship between language-related symptoms and superior temporal gyrus volume is similar to that seen in adult-onset cases but not as lateralized...
Exploring the social brain in schizophrenia: left prefrontal underactivation during mental state attributionT A Russell
Institute of Psychiatry, King s College, London, UK
Am J Psychiatry 157:2040-2. 2000..The authors used functional magnetic resonance imaging (MRI) to investigate the hypothesis that patients with schizophrenia have a dysfunction in brain regions responsible for mental state attribution...
Towards a functional neuroanatomy of self processing: effects of faces and wordsT T Kircher
Department of Psychological Medicine, Institute of Psychiatry and GKT School of Medicine, De Crespigny Park, SE5 8AF, London, UK
Brain Res Cogn Brain Res 10:133-44. 2000..The self-relevant stimuli engaged to a differential extent long term and working memory, semantic and emotional processes. We suggest that regions activated by these stimuli are engaged in self-processing...
Cortical activity during rotational and linear transformationsJ Barnes
Centre for Brain and Cognitive Development, School of Psychology, Birkbeck College, University of London, Malet Street, WC1E 7HX, London, UK
Neuropsychologia 38:1148-56. 2000..The findings demonstrate the extent to which neural substrates for image transformation and perception overlap and are distinct as well as revealing functional specialisation within perception and transformation processing systems...
The functional neuroanatomy of implicit-motion perception or representational momentumC Senior
Department of Psychological Medicine, Institute of Psychiatry and GKT School of Medicine, London, UK
Curr Biol 10:16-22. 2000..We used functional magnetic resonance imaging (fMRI) to explore the neural substrate for representational momentum...
Functional frontalisation with age: mapping neurodevelopmental trajectories with fMRIK Rubia
Institute of Psychiatry King s College, University of London, UK
Neurosci Biobehav Rev 24:13-9. 2000..A significant age effect was found for the prefrontal activation in both task, confirming the hypothesis of a dysmaturational pathogenesis for the hypofrontality in ADHD...
Social intelligence in the normal and autistic brain: an fMRI studyS Baron-Cohen
Departments of Experimental Psychology and Psychiatry, University of Cambridge, UK
Eur J Neurosci 11:1891-8. 1999..These results provide support for the social brain theory of normal function, and the amygdala theory of autism...
Attenuated frontal activation in schizophrenia may be task dependentV A Curtis
Department of Psychological Medicine, Institute of Psychiatry King s College, London, UK
Schizophr Res 37:35-44. 1999..Functional magnetic resonance imaging was used to examine the neural correlates of two linguistic tasks in schizophrenia...
Investigation of facial recognition memory and happy and sad facial expression perception: an fMRI studyM L Phillips
Department of Psychological Medicine, Institute of Psychiatry, London, UK
Psychiatry Res 83:127-38. 1998....
Prefrontal cortex involvement in selective letter generation: a functional magnetic resonance imaging studyG I de Zubicaray
Neuroscience Research Programme, University of Queensland, Australia
Cortex 34:389-401. 1998..These findings are discussed with respect to recent positron emission tomography (PET) and fMRI studies of verbal working memory and encoding/retrieval in episodic memory...
Serial precision of metabolite peak area ratios and water referenced metabolite peak areas in proton MR spectroscopy of the human brainA Simmons
Department of Clinical Neurosciences, Institute of Psychiatry, London, UK
Magn Reson Imaging 16:319-30. 1998..These results allow us to repudiate Marshall's assertion regarding disappointing repeatability of in vivo MRS...
An fMRI study of reduced left prefrontal activation in schizophrenia during normal inhibitory functionK Rubia
Department of Child Psychiatry, Psychological Medicine, and Neurology, Institute of Psychiatry, King s College, De Crespigny Park, SE5 8AF, London, UK
Schizophr Res 52:47-55. 2001..Despite good task performance, patients with schizophrenia thus showed abnormal neural network patterns of reduced left prefrontal activation and increased subcortical activation when challenged with motor response inhibition...
MRI based diffusion and perfusion predictive model to estimate stroke evolutionS E Rose
Centre for Magnetic Resonance, University of Queensland, Brisbane, Queensland 4072, Australia
Magn Reson Imaging 19:1043-53. 2001..97 +/- 0.02, 0.68 +/- 0.07 and 0.97 +/- 0.02. We propose that this automated strategy may allow possible guided therapeutic intervention to stroke patients and evaluation of efficacy of novel stroke compounds in clinical drug trials...
Neural abnormalities during cognitive generation of affect in treatment-resistant depressionVeena Kumari
Section of Cognitive Psychopharmacology, Institute of Psychiatry, King's College, London, UK
Biol Psychiatry 54:777-91. 2003..The results also corroborate previous observations from resting positron emission tomography studies and further elucidate the association between hypoactive rostral cingulate and nonresponsiveness to treatment in depression...
Frontal lobe N-acetylaspartate correlates with psychopathology in schizophrenia: a proton magnetic resonance spectroscopy studyThordur Sigmundsson
Department of Psychological Medicine, Institute of Psychiatry, King's College, De Crespigny Park, London SE5 8AF, UK
Schizophr Res 64:63-71. 2003..The lack of significant mean difference in NAA between the two groups suggests that there is no marked neuronal loss in the dorsolateral prefrontal region in schizophrenia...
Functional magnetic resonance imaging of verbal fluency and confrontation naming using compressed image acquisition to permit overt responsesSharon Abrahams
Institute of Psychiatry, King s College London, United Kingdom
Hum Brain Mapp 20:29-40. 2003....
Cognitive effects of nicotine in humans: an fMRI studyVeena Kumari
Department of Psychology, Institute of Psychiatry, King s College, London, UK
Neuroimage 19:1002-13. 2003....
Neural correlates of tactile prepulse inhibition: a functional MRI study in normal and schizophrenic subjectsVeena Kumari
Section of Cognitive Psychopharmacology, Institute of Psychiatry, King s College, De Crespigny Park, London SE5 8AF, UK
Psychiatry Res 122:99-113. 2003..The findings demonstrate involvement of the striatum, hippocampus, thalamus, and frontal and parietal cortical regions in PPI. Dysfunctions in any of these regions may underlie observations of reduced PPI in schizophrenia...
A computational morphometric MRI study of schizophrenia: effects of hallucinationsJane Shapleske
Department of Psychological Medicine, Institute of Psychiatry, London SE5 8AF, UK
Cereb Cortex 12:1331-41. 2002....
Asperger syndrome: a proton magnetic resonance spectroscopy study of brainDeclan G M Murphy
Department of Psychological Medicine, St George s Hospital Medical School, London, England
Arch Gen Psychiatry 59:885-91. 2002..Nobody has examined the relationship between abnormalities in the frontal and parietal lobes and clinical symptoms in people with AS...
Procedural learning in schizophrenia: a functional magnetic resonance imaging investigationVeena Kumari
Section of Cognitive Psychopharmacology, Division of Psychological Medicine, Institute of Psychiatry, De Crespigny Park, Denmark Hill, London, UK
Schizophr Res 57:97-107. 2002....
Brain anatomy and sensorimotor gating in Asperger's syndromeGrainne M McAlonan
Department of Psychological Medicine, Institute of Psychiatry, London, UK
Brain 125:1594-606. 2002....
Isotropic resolution diffusion tensor imaging with whole brain acquisition in a clinically acceptable timeDerek Kenton Jones
Section of Old Age Psychiatry, Institute of Psychiatry, London SE5 8AF, UK
Hum Brain Mapp 15:216-30. 2002..5 Tesla with isotropic resolution (2.5 x 2.5 x 2.5 mm) from the whole brain within a sufficiently short imaging time that it may be incorporated into clinical imaging protocols...
The neural correlates of intentional and incidental self processingTilo T J Kircher
University of Tuebingen, Department of Psychiatry, Osianderstrasse 24, D 72076 Tubingen, Germany
Neuropsychologia 40:683-92. 2002....
Neuroimaging correlates of negative primingC Steel
Department of Psychology, Institute of Psychiatry, De Crespigny Park, Denmark Hill, London, SE5 8AF, UK
Neuroreport 12:3619-24. 2001..Areas of cortical activation are discussed with reference to theoretical accounts of the negative priming effect...
Differential corticospinal tract degeneration in homozygous 'D90A' SOD-1 ALS and sporadic ALSC R V Blain
Department of Clinical Neuroscience, King s College London, Institute of Psychiatry, London, UK
J Neurol Neurosurg Psychiatry 82:843-9. 2011..The authors aimed to use diffusion tensor tractography to quantify and compare changes in the intracerebral corticospinal tracts of patients with both forms of ALS, building on previous work using whole-brain voxelwise group analysis...
