Mauricio Sierra

Summary

Affiliation: King's College London
Country: UK

Publications

  1. ncbi request reprint Depersonalization disorder: pharmacological approaches
    Mauricio Sierra
    Depersonalization Research Unit, Institute of Psychiatry, King s College, Section of Neuropsychiatry P068, De Crespigny Park, Denmark Hill, London SE5 8AF, UK
    Expert Rev Neurother 8:19-26. 2008
  2. pmc Separating depersonalisation and derealisation: the relevance of the "lesion method"
    M Sierra
    Depersonalisation Research Unit, Institute of Psychiatry, Division of Psychological Medicine, 103 Denmark Hill, London SE5 8AZ, UK
    J Neurol Neurosurg Psychiatry 72:530-2. 2002
  3. ncbi request reprint Depersonalization in psychiatric patients: a transcultural study
    Mauricio Sierra
    Depersonalization Research Unit, Institute of Psychiatry, King s College, London, UK
    J Nerv Ment Dis 194:356-61. 2006
  4. ncbi request reprint A placebo-controlled, cross-over trial of lamotrigine in depersonalization disorder
    Mauricio Sierra
    Institute of Psychiatry, Department of Psychological Medicine, Kings College, London University, London UK
    J Psychopharmacol 17:103-5. 2003
  5. ncbi request reprint Autonomic response in depersonalization disorder
    Mauricio Sierra
    Institute of Psychiatry, 103 Denmark Hill, London SE5 8AZ, England
    Arch Gen Psychiatry 59:833-8. 2002
  6. ncbi request reprint Depersonalization and individualism: the effect of culture on symptom profiles in panic disorder
    Mauricio Sierra-Siegert
    Depersonalization Research Unit, Institute of Psychiatry, King s College, London, UK
    J Nerv Ment Dis 195:989-95. 2007
  7. ncbi request reprint Unpacking the depersonalization syndrome: an exploratory factor analysis on the Cambridge Depersonalization Scale
    Mauricio Sierra
    Depersonalization Research Unit, Psychological Medicine, Institute of Psychiatry, Denmark Hill, London
    Psychol Med 35:1523-32. 2005
  8. ncbi request reprint Lamotrigine as an add-on treatment for depersonalization disorder: a retrospective study of 32 cases
    Mauricio Sierra
    Depersonalisation Research Unit, Psychological Medicine, Institute of Psychiatry, London, UK
    Clin Neuropharmacol 29:253-8. 2006
  9. doi request reprint Cerebral and autonomic responses to emotional facial expressions in depersonalisation disorder
    Erwin Lemche
    Institute of Psychiatry, De Crespigny Park, London SE5 8AF, UK
    Br J Psychiatry 193:222-8. 2008
  10. ncbi request reprint Autonomic response in the perception of disgust and happiness in depersonalization disorder
    Mauricio Sierra
    Institute of Psychiatry, Denmark Hill, London, UK
    Psychiatry Res 145:225-31. 2006

Collaborators

Detail Information

Publications28

  1. ncbi request reprint Depersonalization disorder: pharmacological approaches
    Mauricio Sierra
    Depersonalization Research Unit, Institute of Psychiatry, King s College, Section of Neuropsychiatry P068, De Crespigny Park, Denmark Hill, London SE5 8AF, UK
    Expert Rev Neurother 8:19-26. 2008
    ..In line with the stress-related model of depersonalization, those neurotransmitter systems of relevance to depersonalization are known to play important inhibitory roles in the regulation of the stress response...
  2. pmc Separating depersonalisation and derealisation: the relevance of the "lesion method"
    M Sierra
    Depersonalisation Research Unit, Institute of Psychiatry, Division of Psychological Medicine, 103 Denmark Hill, London SE5 8AZ, UK
    J Neurol Neurosurg Psychiatry 72:530-2. 2002
    ..To overcome this difficulty, we suggest the study of neurological phenomena, which although not considered as DP/DR, bear enough phenomenological resemblance with them as to warrant their use as models...
  3. ncbi request reprint Depersonalization in psychiatric patients: a transcultural study
    Mauricio Sierra
    Depersonalization Research Unit, Institute of Psychiatry, King s College, London, UK
    J Nerv Ment Dis 194:356-61. 2006
    ....
  4. ncbi request reprint A placebo-controlled, cross-over trial of lamotrigine in depersonalization disorder
    Mauricio Sierra
    Institute of Psychiatry, Department of Psychological Medicine, Kings College, London University, London UK
    J Psychopharmacol 17:103-5. 2003
    ..None of the nine patients was deemed a responder to the lamotrigine arm of the cross-over. Lamotrigine does not seem to be useful as a sole medication in the treatment of depersonalization disorder...
  5. ncbi request reprint Autonomic response in depersonalization disorder
    Mauricio Sierra
    Institute of Psychiatry, 103 Denmark Hill, London SE5 8AZ, England
    Arch Gen Psychiatry 59:833-8. 2002
    ..In this study, we tested the prediction that autonomic response to emotional stimuli would be reduced in patients with depersonalization disorder...
  6. ncbi request reprint Depersonalization and individualism: the effect of culture on symptom profiles in panic disorder
    Mauricio Sierra-Siegert
    Depersonalization Research Unit, Institute of Psychiatry, King s College, London, UK
    J Nerv Ment Dis 195:989-95. 2007
    ..Two features may be relevant in the genesis of depersonalization...
  7. ncbi request reprint Unpacking the depersonalization syndrome: an exploratory factor analysis on the Cambridge Depersonalization Scale
    Mauricio Sierra
    Depersonalization Research Unit, Psychological Medicine, Institute of Psychiatry, Denmark Hill, London
    Psychol Med 35:1523-32. 2005
    ..Depersonalization has long been considered a syndrome but there is poor agreement on its constituent symptoms...
  8. ncbi request reprint Lamotrigine as an add-on treatment for depersonalization disorder: a retrospective study of 32 cases
    Mauricio Sierra
    Depersonalisation Research Unit, Psychological Medicine, Institute of Psychiatry, London, UK
    Clin Neuropharmacol 29:253-8. 2006
    ..Lamotrigine as sole agent was not found to be effective in a previous small double-blind, randomized crossover trial. However, evidence from open trials suggests that it may be beneficial as an add-on medication with antidepressants...
  9. doi request reprint Cerebral and autonomic responses to emotional facial expressions in depersonalisation disorder
    Erwin Lemche
    Institute of Psychiatry, De Crespigny Park, London SE5 8AF, UK
    Br J Psychiatry 193:222-8. 2008
    ..Depersonalisation disorder is characterised by emotion suppression, but the cerebral mechanisms of this symptom are not yet fully understood...
  10. ncbi request reprint Autonomic response in the perception of disgust and happiness in depersonalization disorder
    Mauricio Sierra
    Institute of Psychiatry, Denmark Hill, London, UK
    Psychiatry Res 145:225-31. 2006
    ..The findings of this study provide further support to the idea that patients with depersonalization have a selective impairment in the processing of threatening or unpleasant emotional stimuli...
  11. doi request reprint Interoceptive-reflective regions differentiate alexithymia traits in depersonalization disorder
    Erwin Lemche
    Section of Cognitive Neuropsychiatry, Institute of Psychiatry, De Crespigny Park, London SE5 8AF, UK Electronic address
    Psychiatry Res 214:66-72. 2013
    ..The presented analyses provide evidence that alexithymia plays a substantial role in emotional dysregulation in DPD, presumably based on restrictions in interoception. ..
  12. ncbi request reprint Chronic depersonalization following illicit drug use: a controlled analysis of 40 cases
    Nicholas Medford
    Depersonalization Research Unit and Division of Psychological Medicine, Institute of Psychiatry, London, UK
    Addiction 98:1731-6. 2003
    ....
  13. doi request reprint Psychophysiological investigations in depersonalization disorder and effects of electrodermal biofeedback
    Poppy L A Schoenberg
    Depersonalization Research Unit, King s College London, London, England
    J Trauma Dissociation 13:311-29. 2012
    ..Rather than low sympathetic arousal, DPD might be better characterized by abnormal autonomic regulation affecting emotional and physiological responsivity...
  14. ncbi request reprint Cognitive-behaviour therapy for depersonalisation disorder: an open study
    Elaine C M Hunter
    Department of Psychology, Institute of Psychiatry, De Crespigny Park, London SE5 8AF, UK
    Behav Res Ther 43:1121-30. 2005
    ..These initial results suggest that a CBT approach to DPD may be effective, but further trials with larger sample sizes and more rigorous research methodology are needed to determine the specificity of this approach...
  15. doi request reprint Depersonalization disorder and anxiety: a special relationship?
    Mauricio Sierra
    Institute of Psychiatry, King s College, London, UK
    Psychiatry Res 197:123-7. 2012
    ....
  16. ncbi request reprint Depersonalization disorder: thinking without feeling
    M L Phillips
    Depersonalization Research Unit and Division of Psychological Medicine, Institute of Psychiatry, 103 Denmark Hill, SE5 8AF, London, UK
    Psychiatry Res 108:145-60. 2001
    ....
  17. ncbi request reprint Depersonalisation disorder: a cognitive-behavioural conceptualisation
    E C M Hunter
    Department of Psychology, Institute of Psychiatry, De Crespigny Park, London SE5 8AF, UK
    Behav Res Ther 41:1451-67. 2003
    ..A coherent model facilitates the development of potentially effective cognitive and behavioural interventions...
  18. ncbi request reprint Limbic and prefrontal responses to facial emotion expressions in depersonalization
    Erwin Lemche
    Section of Neuroscience and Emotion, Brain Image Analysis Unit, Neuroimaging Research Group, Centre for Neuroimaging Sciences, Institute of Psychiatry, London, UK
    Neuroreport 18:473-7. 2007
    ....
  19. doi request reprint Depersonalization: a selective impairment of self-awareness
    Mauricio Sierra
    Depersonalization Disorder Unit, Institute of Psychiatry, King s College, London, United Kingdom
    Conscious Cogn 20:99-108. 2011
    ....
  20. ncbi request reprint The spectrum of organic depersonalization: a review plus four new cases
    Michelle V Lambert
    Depersonalisation Research Unit of the Division of Psychological Medicine, Institute of Psychiatry, London
    J Neuropsychiatry Clin Neurosci 14:141-54. 2002
    ..The introduction to the DSM-IV of an organic subtype of depersonalization disorder would facilitate research in this area...
  21. ncbi request reprint Depersonalization disorder: a functional neuroanatomical perspective
    Mary L Phillips
    Institute of Psychiatry, Denmark Hill, London, UK
    Stress 6:157-65. 2003
    ..Taken together, these finding suggest that symptoms of depersonalization, and in particular emotional numbing, may be related to a reversal of normal patterns of autonomic and neural response to emotive stimuli...
  22. ncbi request reprint Visual imagery and depersonalisation
    M V Lambert
    Depersonalisation Research Unit, Division of Psychological Medicine, Institute of Psychiatry, London, UK
    Psychopathology 34:259-64. 2001
    ..The findings add further weight to the distinctions made between imagery and perceptual processes...
  23. ncbi request reprint The epidemiology of depersonalisation and derealisation. A systematic review
    E C M Hunter
    Depersonalisation Research Unit, Institute of Psyschiatry, London, UK
    Soc Psychiatry Psychiatr Epidemiol 39:9-18. 2004
    ..Symptoms of depersonalisation (DP) and derealisation (DR) are increasingly recognised in both clinical and non-clinical settings, but their importance and underlying pathophysiology is only now being addressed...
  24. ncbi request reprint The phenomenological stability of depersonalization: comparing the old with the new
    M Sierra
    Institute of Psychiatry, King's College London, Psychological Medicine, United Kingdom
    J Nerv Ment Dis 189:629-36. 2001
    ..Because the neurobiological relevance of the symptoms of depersonalization remains unknown, it makes sense to continue collecting as many symptoms as possible, thereby avoiding both biased selection or premature closure...
  25. ncbi request reprint Depersonalisation disorder: clinical features of 204 cases
    Dawn Baker
    Hartside Unit, St Nicholas Hospital, Gosforth, Newcastle NE3 3XT, London
    Br J Psychiatry 182:428-33. 2003
    ..Depersonalisation disorder is a poorly understood and underresearched syndrome...
  26. ncbi request reprint Emotional memory and perception of emotional faces in patients suffering from depersonalization disorder
    Barbara Montagne
    Utrecht University, The Netherlands
    Br J Psychol 98:517-27. 2007
    ..The results are consistent with altered processing of threat-related stimuli but intact consolidation processes, at least when the stimuli involved are potently arousing...
  27. ncbi request reprint [The measurement of the depersonalisation-derealisation-syndrome with the German version of the Cambridge Depersonalisation Scale (CDS)]
    Matthias Michal
    Klinik für Psychosomatische Medizin und Psychotherapie des Klinikums der J W Goethe Universität Frankfurt am Main
    Psychother Psychosom Med Psychol 54:367-74. 2004
    ..We therefore conclude that the German version of the CDS can be considered as reliable and valid...
  28. ncbi request reprint Risk factors for recurrent nodular goiter after thyroidectomy for benign disease: case-control study of 244 patients
    Helene Gibelin
    Department of Endocrine Surgery, Jean Bernard Hospital, 86000 Poitiers, France
    World J Surg 28:1079-82. 2004
    ..5, NS). Young age and multiple nodules at initial surgery are risk factors for recurrence. A higher rate of temporary morbidity was demonstrated after surgery for recurrent goiter. Total thyroidectomy for multinodular goiter is advisable...