Research Topics
Species | Tom A B SandersSummaryAffiliation: King's College London Country: UK Publications
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Detail Information
Publications
Dietary oleic and palmitic acids and postprandial factor VII in middle-aged men heterozygous and homozygous for factor VII R353Q polymorphismT A Sanders
Nutrition Food and Health Research Centre, King s College London, United Kingdom
Am J Clin Nutr 69:220-5. 1999..The R353Q genotype is a major determinant of factor VII coagulant (FVIIc) activity, which is associated with an increased risk of ischemic heart disease (IHD) and elevated plasma triacylglycerol concentrations...- Food safety and risk assessment: naturally occurring potential toxicants and anti-nutritive compounds in plant foodsThomas A B Sanders
Nutrition Food and Health Research Centre, London, UK
Forum Nutr 56:407-9. 2003..The occurrence of a number of fatalities in developing countries among people consuming herbal teas and dietary supplements underscores the need to assess the safety of these products before they are placed on the market... - Diet and general health: dietary counsellingThomas A B Sanders
Nutrition, Food and Health Research Centre, King s College London, UK
Caries Res 38:3-8. 2004..A need for randomized controlled trials to assess the effectiveness of dietary modification on oral health in adults is identified... - Influence of stearic acid on postprandial lipemia and hemostatic functionThomas A B Sanders
Nutritional Sciences Research Division, King s College London, London SE1 9NH, England
Lipids 40:1221-7. 2005..The difference in responses between the different stearic acid-rich fats appears to be due to varying solid fat contents of the fats at 37 degrees C... - Dietary fat and postprandial lipidsTom A B Sanders
Nutrition Food and Health Research Centre, King s College London, Franklin Wilkins Building, 150 Stamford Street, London SE1 9NN, United Kingdom
Curr Atheroscler Rep 5:445-51. 2003.... - Influence of an algal triacylglycerol containing docosahexaenoic acid (22 : 6n-3) and docosapentaenoic acid (22 : 5n-6) on cardiovascular risk factors in healthy men and womenThomas A B Sanders
Nutritional Sciences Research Division, Franklin Wilkins Building, King s College London, UK
Br J Nutr 95:525-31. 2006..Overall, the oil was well tolerated and did not adversely affect cardiovascular risk... - High intakes of trans monounsaturated fatty acids taken for 2 weeks do not influence procoagulant and fibrinolytic risk markers for CHD in young healthy menThomas A B Sanders
Nutrition Food and Health Research Centre, King s College London, Franklin Wilkins Building, 150 Stamford Street, London, SE1 9NN, UK
Br J Nutr 89:767-76. 2003.... - Effect of varying the ratio of n-6 to n-3 fatty acids by increasing the dietary intake of alpha-linolenic acid, eicosapentaenoic and docosahexaenoic acid, or both on fibrinogen and clotting factors VII and XII in persons aged 45-70 y: the OPTILIP studyThomas A B Sanders
Nutritional Sciences Research Division, King s College London, London, United Kingdom
Am J Clin Nutr 84:513-22. 2006..This study tested the hypothesis that lowering the dietary ratio of n-6 to n-3 polyunsaturated fatty acids (n-6:n-3) would modify these risk factors in older men and women... - Influence of triacylglycerol structure on the postprandial response of factor VII to stearic acid-rich fatsThomas A B Sanders
Department of Nutrition and Dietetics, Nutrition Food and Health Research Centre, King s College London, United Kingdom
Am J Clin Nutr 77:777-82. 2003..It was hypothesized that this difference is a consequence of the differences in structure between the 2 triacylglycerols... - High- versus low-fat diets in human diseasesTom A B Sanders
Nutrition Food and Health Research Centre, King s College London, London, UK
Curr Opin Clin Nutr Metab Care 6:151-5. 2003..To evaluate the evidence with regard to high-versus low-fat diets in the context of the prevention and management of obesity, type 2 diabetes and coronary heart disease... - Moderate intakes of intact soy protein rich in isoflavones compared with ethanol-extracted soy protein increase HDL but do not influence transforming growth factor beta(1) concentrations and hemostatic risk factors for coronary heart disease in healthy suThomas A B Sanders
Nutrition, Food and Health Research Centre, King s College London, United Kingdom
Am J Clin Nutr 76:373-7. 2002..Soybeans contain estrogenic isoflavones that may influence plasma concentrations of transforming growth factor beta(1) (TGF-beta(1)) and plasma lipid and hemostatic risk factors for coronary heart disease... - DHA status of vegetariansThomas A B Sanders
Nutritional Sciences Division TABS, King s College London, Franklin Wilkins Building, 150 Stamford Street, London SE19NH, UK
Prostaglandins Leukot Essent Fatty Acids 81:137-41. 2009..Docosahexaenoic acid (22:6n-3; DHA) is absent from vegan diets and present in limited amounts in vegetarian diets... - Effect of low doses of long-chain n-3 PUFAs on endothelial function and arterial stiffness: a randomized controlled trialThomas A B Sanders
Diabetes and Nutritional Sciences Division, School of Medicine, King s College London, London, United Kingdom
Am J Clin Nutr 94:973-80. 2011..The dietary intake of n-3 (omega-3) long-chain PUFAs (LC-PUFAs) from fish may improve endothelial function and arterial stiffness... - Influence of a stearic acid-rich structured triacylglycerol on postprandial lipemia, factor VII concentrations, and fibrinolytic activity in healthy subjectsT A Sanders
Nutrition Food and Health Research Centre, King s College London, London, Unted Kingdom
Am J Clin Nutr 73:715-21. 2001..An elevated postprandial lipid concentration is believed to be atherogenic and to increase the risk of thrombosis... - Influence of fatty acid chain length and cis/trans isomerization on postprandial lipemia and factor VII in healthy subjects (postprandial lipids and factor VII)T A Sanders
Nutrition Food and Health Research Centre, King s College London, Franklin Wilkins Building, 150 Stamford Street, London, UK
Atherosclerosis 149:413-20. 2000..These results do not support the hypothesis that dietary stearate and elaidate are responsible for the postprandial increases in FVII associated with high fat intakes... - Polyunsaturated fatty acids in the food chain in EuropeT A Sanders
Nutrition, Food and Health Research Centre, King s College London, UK
Am J Clin Nutr 71:176S-8S. 2000..Overall, there has been a shift in the balance between n-6 and n-3 fatty acids over the past 30 y. This shift is reflected in the declining concentrations of docosahexaenoic acid and rising concentrations of linoleic acid in breast milk... - Essential fatty acid requirements of vegetarians in pregnancy, lactation, and infancyT A Sanders
Nutrition, Food and Health Research Centre, King s College London, United Kingdom
Am J Clin Nutr 70:555S-559S. 1999.... - The nutritional adequacy of plant-based dietsT A Sanders
Nutrition Food and Health Research Centre, King s College London, UK
Proc Nutr Soc 58:265-9. 1999..Well-balanced vegetarian diets are able to support normal growth and development. It is concluded that meat is an optional rather than an essential constituent of human diets... - Postprandial variations in fibrinolytic activity in middle-aged men are modulated by plasminogen activator inhibitor I 4G-675/5G genotype but not by the fat content of a mealThomas A B Sanders
Nutrition Food and Health Research Centre, King s College London, United Kingdom
Am J Clin Nutr 79:577-81. 2004..Decreased fibrinolytic activity is associated with an increased risk of ischemic heart disease and elevated plasma triacylglycerol concentrations... - Palmitic acid in the sn-2 position of triacylglycerols acutely influences postprandial lipid metabolismThomas A B Sanders
Diabetes and Nutritional Sciences Division, School of Medicine, King s College London, United Kingdom
Am J Clin Nutr 94:1433-41. 2011..The triacylglycerol structure of saturated fats may influence postprandial lipemia... - UK Food Standards Agency Workshop Report: carbohydrate and cardiovascular riskEmma Peacock
Nutrition Division, Food Standards Agency, London, UK
Br J Nutr 103:1688-94. 2010..Results of these trials will make a substantive contribution to the evidence on diet and cardiovascular risk... - UK Food Standards Agency cis-monounsaturated fatty acid workshop reportPeter Sanderson
Nutrition Division, Food Standards Agency, Aviation House, 125 Kingsway, London, WC2 6NH, UK
Br J Nutr 88:99-104. 2002..Recommendations for studies investigating the mechanistic effects of MUFA were also made. Methods of manipulating the food chain to increase MUFA at the expense of saturated fatty acids were also discussed... - Low-dose docosahexaenoic acid lowers diastolic blood pressure in middle-aged men and womenHannah E Theobald
Nutritional Sciences Research Division, King s College London SE1 9NH, UK
J Nutr 137:973-8. 2007..15). The results indicate that a moderate increase in the daily intake of DHA to approximately 0.7 g DHA lowers diastolic BP but does not influence indices of endothelial function or arterial stiffness in the short term... - A high-fat meal enriched with eicosapentaenoic acid reduces postprandial arterial stiffness measured by digital volume pulse analysis in healthy menWendy L Hall
Nutritional Sciences Division, School of Biomedical and Health Sciences, King s College London, London SE1 7EH UK
J Nutr 138:287-91. 2008..Changes in other variables measured also did not differ after subjects consumed the 2 meals. In conclusion, adding EPA to a high-fat meal results in acute changes in vascular tone, independent of changes in oxidative stress... - The solid fat content of stearic acid-rich fats determines their postprandial effectsSarah E E Berry
Nutritional Sciences Research Division, King s College London, London, United Kingdom
Am J Clin Nutr 85:1486-94. 2007..The process of randomization is used commercially to harden fats as an alternative to partial hydrogenation, but its effects on cardiovascular disease risk factors are uncertain... - Impaired postprandial endothelial function depends on the type of fat consumed by healthy menSarah E E Berry
Nutritional Sciences Division, King s College London, London SE1 9NH, United Kingdom
J Nutr 138:1910-4. 2008.... - Asymmetric dimethylarginine and reduced nitric oxide bioavailability in young Black African menNarbeh Melikian
Cardiovascular Division, King s College London School of Medicine at Guy s, King s College and St Thomas Hospitals, London, United Kingdom
Hypertension 49:873-7. 2007..This may contribute to the lower NO bioavailability and higher incidence of cardiovascular disease seen in black Africans... - Effect of interesterification of palmitic acid-rich triacylglycerol on postprandial lipid and factor VII responseSarah E E Berry
Department of Nutrition and Dietetics, Nutritional Sciences Research Division, King s College London, Franklin Wilkins Building, 150 Stamford Street, London, SE1 9NH, UK
Lipids 42:315-23. 2007..It is concluded that interesterification of palm oil does not result in adverse changes in postprandial lipids, insulin or FVIIa compared to high oleate and native palm oils... - Folate status, genomic DNA hypomethylation, and risk of colorectal adenoma and cancer: a case control studyMaria Pufulete
Nutrition Food and Health Research Centre, Department of Nutrition and Dietetics, King s College London, United Kingdom
Gastroenterology 124:1240-8. 2003.... - Folate, DNA methylation and colo-rectal cancerMaria Pufulete
Nutrition Food and Health Research Centre, King s College London, 150 Stamford Street, London SE1 9NN, UK
Proc Nutr Soc 62:437-45. 2003..05) and colonic mucosa (P = 0.09). Further studies are required to confirm these findings in larger populations and to define abnormal ranges of DNA methylation... - Postprandial lipaemia does not affect resting haemodynamic responses but does influence cardiovascular reactivity to dynamic exerciseVictoria G Rontoyanni
Nutritional Sciences Division, King s College London, Franklin Wilkins Building, 150 Stamford Street, London SE1 9NH, UK
Br J Nutr 104:863-71. 2010..Postprandial lipaemia induced by a HFM does not affect cardiac output and/or SVR at rest, but it blunts the increase in BP during exercise... - Influence of triacylglycerol structure of stearic acid-rich fats on postprandial lipaemiaSarah E E Berry
Nutrition Food and Health Research Centre, King s College London, Franklin Wilkins Building, 150 Stamford Street, London SE1 9NH, UK
Proc Nutr Soc 64:205-12. 2005.... - A meal enriched with soy isoflavones increases nitric oxide-mediated vasodilation in healthy postmenopausal womenWendy L Hall
Nutritional Sciences Division, School of Biomedical and Health Sciences, King s College London, London SE1 9NH, UK
J Nutr 138:1288-92. 2008..In conclusion, consuming an isoflavone-enriched low-fat meal acutely increases endothelium-dependent vasodilation in postmenopausal women. Regular consumption of soy isoflavones may protect against endothelial dysfunction... - Nutrition and therapeuticsTom A B Sanders
Nutrition Food and Health Research Centre, King's College London, UK
Curr Opin Lipidol 15:357-9. 2004 - LDL cholesterol-raising effect of low-dose docosahexaenoic acid in middle-aged men and womenHannah E Theobald
Nutrition Food and Health Research Centre, King's College London, London, United Kingdom
Am J Clin Nutr 79:558-63. 2004..CONCLUSION: A daily intake of approximately 0.7 g DHA increases LDL cholesterol by 7% in middle-aged men and women. It is suggested that DHA down-regulates the expression of the LDL receptor... - Holotranscobalamin as an indicator of dietary vitamin B12 deficiencyZouë Lloyd-Wright
Nutrition Food and Health Research Centre, King s College London, Franklin Wilkins Bldg, 150 Stamford St, Waterloo, London SE1 9NN, United Kingdom
Clin Chem 49:2076-8. 2003 - Validation of a short food frequency questionnaire to assess folate intakeMaria Pufulete
Nutrition, Food and Health Research Centre, King's College London, UK
Br J Nutr 87:383-90. 2002..Overall, these results suggest that this short FFQ is a useful method for assessing folate intake, particularly in men... - Effects of altering the ratio of dietary n-6 to n-3 fatty acids on insulin sensitivity, lipoprotein size, and postprandial lipemia in men and postmenopausal women aged 45-70 y: the OPTILIP StudyMargaret D Griffin
School of Biomedical and Molecular Sciences, University of Surrey, Guildford, Surrey, United Kingdom
Am J Clin Nutr 84:1290-8. 2006..The reduction in plasma triacylglycerol after an increased intake of n-3 long-chain PUFAs results in favorable changes in LDL size... - Long-chain n-3 polyunsaturated fatty acids in plasma in British meat-eating, vegetarian, and vegan menMagdalena S Rosell
Cancer Research UK Epidemiology Unit, University of Oxford, Oxford, United Kingdom
Am J Clin Nutr 82:327-34. 2005..Plasma concentrations of long-chain n-3 polyunsaturated fatty acids are lower in vegetarians and in vegans than in omnivores. No data are available on whether these concentrations differ between long- and short-term vegetarians and vegans...