Katya Rubia

Summary

Affiliation: King's College London
Country: UK

Publications

  1. ncbi request reprint The dynamic approach to neurodevelopmental psychiatric disorders: use of fMRI combined with neuropsychology to elucidate the dynamics of psychiatric disorders, exemplified in ADHD and schizophrenia
    Katya Rubia
    Department of Child and Adolescent Psychiatry Unit, Institute of Psychiatry Kings College, De Crespigny Park, London SE 8AF, UK
    Behav Brain Res 130:47-56. 2002
  2. doi request reprint Shared and disorder-specific prefrontal abnormalities in boys with pure attention-deficit/hyperactivity disorder compared to boys with pure CD during interference inhibition and attention allocation
    Katya Rubia
    Department of Child Psychiatry, Institute of Psychiatry, King s College, London, UK
    J Child Psychol Psychiatry 50:669-78. 2009
  3. doi request reprint Total red blood cell concentrations of omega-3 fatty acids are associated with emotion-elicited neural activity in adolescent boys with attention-deficit hyperactivity disorder
    Rachel V Gow
    Department of Child and Adolescent Psychiatry, PO Box 85, Institute of Psychiatry, De Crespigny Park, Denmark Hill, London SE58AF, UK
    Prostaglandins Leukot Essent Fatty Acids 80:151-6. 2009
  4. doi request reprint Reduced activation in lateral prefrontal cortex and anterior cingulate during attention and cognitive control functions in medication-naïve adolescents with depression compared to controls
    Rozmin Halari
    Child and Adolescent Psychiatry, Institute of Psychiatry, London, UK
    J Child Psychol Psychiatry 50:307-16. 2009
  5. doi request reprint Disorder-specific dissociation of orbitofrontal dysfunction in boys with pure conduct disorder during reward and ventrolateral prefrontal dysfunction in boys with pure ADHD during sustained attention
    Katya Rubia
    Department of Child Psychiatry MRC Center for Social, Genetic and Developmental Psychiatry SGDP, Institute of Psychiatry, King s College, 16 De Crespigny Park, London, SE5 8AF, UK
    Am J Psychiatry 166:83-94. 2009
  6. doi request reprint Reduced activation in right lateral prefrontal cortex and anterior cingulate gyrus in medication-naïve adolescents with attention deficit hyperactivity disorder during time discrimination
    Anna B Smith
    Centre for Social Genetic and Developmental Psychiatry, Institute of Psychiatry, King s College, London, UK
    J Child Psychol Psychiatry 49:977-85. 2008
  7. doi request reprint Dissociated functional brain abnormalities of inhibition in boys with pure conduct disorder and in boys with pure attention deficit hyperactivity disorder
    Katya Rubia
    Department of Child Psychiatry MRC Center for Social, Genetic, and Developmental Psychiatry, Institute of Psychiatry, King s College, London SE5 8AF, UK
    Am J Psychiatry 165:889-97. 2008
  8. doi request reprint The neural basis of response inhibition and attention allocation as mediated by gestational age
    Emma J Lawrence
    Department of Psychological Medicine, Institute of Psychiatry, King s College London, United Kingdom
    Hum Brain Mapp 30:1038-50. 2009
  9. doi request reprint Brain activation in paediatric obsessive compulsive disorder during tasks of inhibitory control
    James Woolley
    Child and Adolescent Psychiatry PO 46, Institute of Psychiatry, Denmark Hill, London SE5 8AF, UK
    Br J Psychiatry 192:25-31. 2008
  10. doi request reprint The neurobiology of Meditation and its clinical effectiveness in psychiatric disorders
    Katya Rubia
    Institute of Psychiatry, Department of Child and Adolescent Psychiatry, King s College University London, UK
    Biol Psychol 82:1-11. 2009

Detail Information

Publications43

  1. ncbi request reprint The dynamic approach to neurodevelopmental psychiatric disorders: use of fMRI combined with neuropsychology to elucidate the dynamics of psychiatric disorders, exemplified in ADHD and schizophrenia
    Katya Rubia
    Department of Child and Adolescent Psychiatry Unit, Institute of Psychiatry Kings College, De Crespigny Park, London SE 8AF, UK
    Behav Brain Res 130:47-56. 2002
    ..Comparisons between patient groups will be essential to address the specificity of neurocognitive mechanisms corresponding to specific neurodevelopmental psychiatric disorders...
  2. doi request reprint Shared and disorder-specific prefrontal abnormalities in boys with pure attention-deficit/hyperactivity disorder compared to boys with pure CD during interference inhibition and attention allocation
    Katya Rubia
    Department of Child Psychiatry, Institute of Psychiatry, King s College, London, UK
    J Child Psychol Psychiatry 50:669-78. 2009
    ..This study investigates differences and commonalities in functional neural networks mediating interference inhibition and attention allocation between medication-naïve children and adolescents with pure CD and those with pure ADHD...
  3. doi request reprint Total red blood cell concentrations of omega-3 fatty acids are associated with emotion-elicited neural activity in adolescent boys with attention-deficit hyperactivity disorder
    Rachel V Gow
    Department of Child and Adolescent Psychiatry, PO Box 85, Institute of Psychiatry, De Crespigny Park, Denmark Hill, London SE58AF, UK
    Prostaglandins Leukot Essent Fatty Acids 80:151-6. 2009
    ....
  4. doi request reprint Reduced activation in lateral prefrontal cortex and anterior cingulate during attention and cognitive control functions in medication-naïve adolescents with depression compared to controls
    Rozmin Halari
    Child and Adolescent Psychiatry, Institute of Psychiatry, London, UK
    J Child Psychol Psychiatry 50:307-16. 2009
    ..This study investigated whether medication-naïve adolescents with MDD show abnormal brain activation of fronto-striatal and fronto-cingulate networks when performing tasks of attentional and cognitive control...
  5. doi request reprint Disorder-specific dissociation of orbitofrontal dysfunction in boys with pure conduct disorder during reward and ventrolateral prefrontal dysfunction in boys with pure ADHD during sustained attention
    Katya Rubia
    Department of Child Psychiatry MRC Center for Social, Genetic and Developmental Psychiatry SGDP, Institute of Psychiatry, King s College, 16 De Crespigny Park, London, SE5 8AF, UK
    Am J Psychiatry 166:83-94. 2009
    ....
  6. doi request reprint Reduced activation in right lateral prefrontal cortex and anterior cingulate gyrus in medication-naïve adolescents with attention deficit hyperactivity disorder during time discrimination
    Anna B Smith
    Centre for Social Genetic and Developmental Psychiatry, Institute of Psychiatry, King s College, London, UK
    J Child Psychol Psychiatry 49:977-85. 2008
    ..We investigated the neuro-anatomical substrates mediating fine temporal discrimination in adolescents with ADHD compared with controls, using functional magnetic resonance imaging (fMRI)...
  7. doi request reprint Dissociated functional brain abnormalities of inhibition in boys with pure conduct disorder and in boys with pure attention deficit hyperactivity disorder
    Katya Rubia
    Department of Child Psychiatry MRC Center for Social, Genetic, and Developmental Psychiatry, Institute of Psychiatry, King s College, London SE5 8AF, UK
    Am J Psychiatry 165:889-97. 2008
    ....
  8. doi request reprint The neural basis of response inhibition and attention allocation as mediated by gestational age
    Emma J Lawrence
    Department of Psychological Medicine, Institute of Psychiatry, King s College London, United Kingdom
    Hum Brain Mapp 30:1038-50. 2009
    ....
  9. doi request reprint Brain activation in paediatric obsessive compulsive disorder during tasks of inhibitory control
    James Woolley
    Child and Adolescent Psychiatry PO 46, Institute of Psychiatry, Denmark Hill, London SE5 8AF, UK
    Br J Psychiatry 192:25-31. 2008
    ..Obsessive-compulsive disorder (OCD) may be related to a dysfunction in frontostriatal pathways mediating inhibitory control. However, no functional magnetic resonance imaging (fMRI) study has tested this in children...
  10. doi request reprint The neurobiology of Meditation and its clinical effectiveness in psychiatric disorders
    Katya Rubia
    Institute of Psychiatry, Department of Child and Adolescent Psychiatry, King s College University London, UK
    Biol Psychol 82:1-11. 2009
    ....
  11. pmc Impulsiveness as a timing disturbance: neurocognitive abnormalities in attention-deficit hyperactivity disorder during temporal processes and normalization with methylphenidate
    Katya Rubia
    Department of Child Psychiatry MRC Center for Social, Genetic and Developmental Psychiatry SGDP, Institute of Psychiatry, 16 De Crespigny Park, London, UK
    Philos Trans R Soc Lond B Biol Sci 364:1919-31. 2009
    ....
  12. doi request reprint Methylphenidate normalises activation and functional connectivity deficits in attention and motivation networks in medication-naïve children with ADHD during a rewarded continuous performance task
    Katya Rubia
    Department of Child Psychiatry, Institute of Psychiatry, King s College, London, UK
    Neuropharmacology 57:640-52. 2009
    ....
  13. doi request reprint Disorder-specific dysfunctions in patients with attention-deficit/hyperactivity disorder compared to patients with obsessive-compulsive disorder during interference inhibition and attention allocation
    Katya Rubia
    Department of Child Psychiatry, Institute of Psychiatry, King s College London, London, UK
    Hum Brain Mapp 32:601-11. 2011
    ..The aim of this study was to investigate disorder-specific abnormalities in neural networks mediating interference inhibition and selective attention...
  14. doi request reprint Structural and functional brain imaging in adult attention-deficit/hyperactivity disorder
    Ana Cubillo
    Department of Child Psychiatry SGDP, P046, Institute of Psychiatry, 16 De Crespigny Park, London, SE5 8AF, UK
    Expert Rev Neurother 10:603-20. 2010
    ....
  15. doi request reprint Disorder-specific inferior prefrontal hypofunction in boys with pure attention-deficit/hyperactivity disorder compared to boys with pure conduct disorder during cognitive flexibility
    Katya Rubia
    Department of Child Psychiatry, MRC Center for Social, Genetic and Developmental Psychiatry, Institute of Psychiatry, King s College, London, United Kingdom
    Hum Brain Mapp 31:1823-33. 2010
    ..This study investigates disorder-specific functional abnormalities during cognitive flexibility between medication-naïve children and adolescents with noncomorbid CD and those with noncomorbid ADHD compared to healthy controls...
  16. doi request reprint Effects of age and sex on developmental neural networks of visual-spatial attention allocation
    Katya Rubia
    Department of Child and Adolescent Psychiatry, Institute of Psychiatry, King s College London, UK
    Neuroimage 51:817-27. 2010
    ....
  17. doi request reprint Reduced activation and inter-regional functional connectivity of fronto-striatal networks in adults with childhood Attention-Deficit Hyperactivity Disorder (ADHD) and persisting symptoms during tasks of motor inhibition and cognitive switching
    Ana Cubillo
    Department of Child Psychiatry, Institute of Psychiatry, King s College, London SE5 8AF, UK
    J Psychiatr Res 44:629-39. 2010
    ..This suggests that neuro-functional abnormalities in ADHD patients are likely to continue between childhood and early adulthood...
  18. doi request reprint A functional magnetic resonance imaging study of inhibitory control in obsessive-compulsive disorder
    Lisa A Page
    King s College London, Division of Psychological Medicine and Psychiatry, Institute of Psychiatry, Room 3 14, Weston Education Centre, 10 Cutcombe Road, London, SE5 9RJ, UK
    Psychiatry Res 174:202-9. 2009
    ..OCD is associated with task-relevant fronto-striatal dysfunction during motor inhibition and cognitive switching. In addition, parieto-temporal dysfunction was observed during tasks with a higher attentional load...
  19. doi request reprint Disorder-specific dysfunction in right inferior prefrontal cortex during two inhibition tasks in boys with attention-deficit hyperactivity disorder compared to boys with obsessive-compulsive disorder
    Katya Rubia
    Department of Child Psychiatry, Institute of Psychiatry, King s College, London, United Kingdom
    Hum Brain Mapp 31:287-99. 2010
    ....
  20. doi request reprint Right ventromedial and dorsolateral prefrontal cortices mediate adaptive decisions under ambiguity by integrating choice utility and outcome evaluation
    Anastasia Christakou
    Department of Child and Adolescent Psychiatry, Institute of Psychiatry, King s College London, De Crespigny Park, London SE5 8AF, United Kingdom
    J Neurosci 29:11020-8. 2009
    ..These findings provide functional evidence of the underlying processes by which these prefrontal subregions drive adaptive choice in the task, namely through contingency-sensitive outcome evaluation...
  21. doi request reprint Neural basis of Delta-9-tetrahydrocannabinol and cannabidiol: effects during response inhibition
    Stefan J Borgwardt
    Section of Neuroimaging, Institute of Psychiatry, King s College London, United Kingdom
    Biol Psychiatry 64:966-73. 2008
    ..This study examined the effect of Delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD) on brain activation during a motor inhibition task...
  22. pmc Neuro-anatomic evidence for the maturational delay hypothesis of ADHD
    Katya Rubia
    Department of Child Psychiatry Medical Research Council Social, Genetic, and Developmental Psychiatry Research Center SGDP, Institute of Psychiatry, 16 De Crespigny Park, SG DP PO46, London SE5 8AF, United Kingdom
    Proc Natl Acad Sci U S A 104:19663-4. 2007
  23. ncbi request reprint Motor timing deficits in community and clinical boys with hyperactive behavior: the effect of methylphenidate on motor timing
    Katya Rubia
    Institute of Psychiatry, King s College London, London, United Kingdom
    J Abnorm Child Psychol 31:301-13. 2003
    ....
  24. ncbi request reprint A right hemispheric frontocerebellar network for time discrimination of several hundreds of milliseconds
    Anna Smith
    Department of Child and Adolescent Psychiatry, Institute of Psychiatry, London, UK
    Neuroimage 20:344-50. 2003
    ..We conclude that right DLPFC, rather than having a purely working memory function, might be more centrally involved in time perception than previously thought...
  25. ncbi request reprint Right inferior prefrontal cortex mediates response inhibition while mesial prefrontal cortex is responsible for error detection
    Katya Rubia
    Institute of Psychiatry, King s College London, De Crespigny Park, London SE5 8AF, UK
    Neuroimage 20:351-8. 2003
    ..Failure to inhibit was associated with activation in mesial frontopolar and bilateral inferior parietal cortices, presumably reflecting an attention network for error detection...
  26. ncbi request reprint Abnormal brain activation during inhibition and error detection in medication-naive adolescents with ADHD
    Katya Rubia
    Department of Psychiatry, Institute of Psychiatry, 16 De Crespigny Park, London SE5 8AF, UK
    Am J Psychiatry 162:1067-75. 2005
    ....
  27. ncbi request reprint The neural correlates of cognitive time management: a review
    Katya Rubia
    Department of Child and Adolescent Psychiatry, Institute of Psychiatry, London, United Kingdom
    Acta Neurobiol Exp (Wars) 64:329-40. 2004
    ..The review shows that the same brain regions are involved in both motor timing and time estimation, suggesting that both functions are probably inseparable and mediated by common neural networks...
  28. ncbi request reprint Tryptophan depletion reduces right inferior prefrontal activation during response inhibition in fast, event-related fMRI
    Katya Rubia
    Institute of Psychiatry, King s College London, De Crespigny Park, SE5 8AF, London, UK
    Psychopharmacology (Berl) 179:791-803. 2005
    ....
  29. ncbi request reprint Evidence for a pure time perception deficit in children with ADHD
    Anna Smith
    Department of Child and Adolescent Psychiatry, Institute of Psychiatry, London, UK
    J Child Psychol Psychiatry 43:529-42. 2002
    ..The aim of this study was to explore further the abilities of hyperactive children in skills of time estimation, using a range of time perception tasks in different temporal domains...
  30. ncbi request reprint Altered functional neuroanatomy of response inhibition in adolescent males who were born very preterm
    Chiara Nosarti
    Division of Psychological Medicine, Institute of Psychiatry, London, UK
    Dev Med Child Neurol 48:265-71. 2006
    ....
  31. ncbi request reprint Progressive increase of frontostriatal brain activation from childhood to adulthood during event-related tasks of cognitive control
    Katya Rubia
    Department of Child Psychiatry, Institute of Psychiatry, King s College, London, UK
    Hum Brain Mapp 27:973-93. 2006
    ..The findings suggest progressive maturation of task-specific frontostriatal and frontocortical networks for cognitive control functions in the transition from childhood to mid-adulthood...
  32. ncbi request reprint 5-HT, prefrontal function and aging: fMRI of inhibition and acute tryptophan depletion
    Melissa Lamar
    Department of Psychology, Institute of Psychiatry, King s College London, London, UK
    Neurobiol Aging 30:1135-46. 2009
    ..Maintaining successful Simon performance during ATD is achieved by increasing cerebellar and parietal contributions to compensate for decreased fronto-cingulo-striatal involvement...
  33. ncbi request reprint Temporal lobe dysfunction in medication-naïve boys with attention-deficit/hyperactivity disorder during attention allocation and its relation to response variability
    Katya Rubia
    Department of Child Psychiatry, Institute of Psychiatry, King s College, London, United Kingdom
    Biol Psychiatry 62:999-1006. 2007
    ..Furthermore, we explore the relationship between the neural substrates of attention allocation and response variability, typically increased in patients...
  34. ncbi request reprint Performance of children with attention deficit hyperactivity disorder (ADHD) on a test battery of impulsiveness
    Katya Rubia
    Department of Child and Adolescent Psychiatry, Institute of Psychiatry, Kings College, London, UK
    Child Neuropsychol 13:276-304. 2007
    ..The task battery as a whole showed 76% correct discrimination of cases and controls...
  35. ncbi request reprint Heterozygous PAX6 mutation, adult brain structure and fronto-striato-thalamic function in a human family
    Zoë Ellison-Wright
    Institute of Psychiatry, King s College London, De Crespigny Park, London SE5 8AF, UK
    Eur J Neurosci 19:1505-12. 2004
    ..Highly conserved homeobox genes may be critical for normal ontogenesis of large-scale neurocognitive networks supporting phylogenetically advanced mental functions...
  36. ncbi request reprint Linear age-correlated functional development of right inferior fronto-striato-cerebellar networks during response inhibition and anterior cingulate during error-related processes
    Katya Rubia
    Department of Child Psychiatry, Institute of Psychiatry, London SE5 8AF, United Kingdom
    Hum Brain Mapp 28:1163-77. 2007
    ..This study shows developmental specialization of the integrated function of right inferior prefrontal cortex, basal ganglia, thalamus, and cerebellum for inhibitory control and of anterior cingulate gyrus for error-related processes...
  37. doi request reprint Frontal lobe structure and executive function in migraine patients
    Nicole Schmitz
    Department of Radiology, Leiden University Medical Centre, Albinusdreef 2, 2300 RC, Leiden, The Netherlands
    Neurosci Lett 440:92-6. 2008
    ..Frontal and parietal lobe abnormalities in migraineurs could be an underlying cause of significantly slower response time during cognitive set-shifting...
  38. ncbi request reprint Task-specific hypoactivation in prefrontal and temporoparietal brain regions during motor inhibition and task switching in medication-naive children and adolescents with attention deficit hyperactivity disorder
    Anna B Smith
    Department of Child Psychiatry, Institute of Psychiatry, King s College, London, SE5 8AF, UK
    Am J Psychiatry 163:1044-51. 2006
    ..The aim of this study was to investigate the neural substrates of a range of motor and cognitive inhibitory functions in a relatively large group of children and adolescents with ADHD who had never previously been exposed to medication...
  39. doi request reprint Neural correlates of reward in autism
    Nicole Schmitz
    Amsterdam Medical Centre, Department of Psychiatry, Amsterdam, The Netherlands
    Br J Psychiatry 192:19-24. 2008
    ..However, no reported in vivo brain imaging studies have investigated reward mechanisms in autistic-spectrum disorder...
  40. ncbi request reprint Towards an understanding of unique and shared pathways in the psychopathophysiology of ADHD
    Tobias Banaschewski
    Child and Adolescent Psychiatry, University of Gottingen, Von Siebold Str 5, D 37075 Gottingen, Germany
    Dev Sci 8:132-40. 2005
    ....
  41. ncbi request reprint Neural correlates of switching set as measured in fast, event-related functional magnetic resonance imaging
    Anna B Smith
    Department of Child Psychiatry, Institute of Psychiatry, King s College London, London, United Kingdom
    Hum Brain Mapp 21:247-56. 2004
    ..We conclude that left DLPFC activation is involved directly in cognitive switching, in conjunction with parietal and temporal brain regions. Pre- and postcentral gyrus activation may be related to motor components of switching set...
  42. ncbi request reprint Conduct problems in adolescence: three domains of inhibition and effect of gender
    Catherine M Herba
    Department of Child and Adolescent Psychiatry, Erasmus Medical Center Sophia Children s Hospital, 3000 CB Rotterdam, The Netherlands
    Dev Neuropsychol 30:659-95. 2006
    ....
  43. ncbi request reprint Neural correlates of executive function in autistic spectrum disorders
    Nicole Schmitz
    Department of Psychological Medicine, Section of Brain Maturation, Institute of Psychiatry, King College London, UK
    Biol Psychiatry 59:7-16. 2006
    ..However, to date, no functional imaging study on ASD has investigated inhibition and cognitive flexibility and no one has related EF brain activation to brain structure...