P Rezaie

Summary

Affiliation: King's College London
Country: UK

Publications

  1. ncbi request reprint Motility and ramification of human fetal microglia in culture: an investigation using time-lapse video microscopy and image analysis
    P Rezaie
    Department of Neuropathology, Institute of Psychiatry, King s College London, DeCrespigny Park, London, SE5 8AF, United Kingdom
    Exp Cell Res 274:68-82. 2002
  2. ncbi request reprint Microglia in the human fetal spinal cord--patterns of distribution, morphology and phenotype
    P Rezaie
    Department of Neuropathology, Institute of Psychiatry, De Crespigny Park, London SE5 8JN, UK
    Brain Res Dev Brain Res 115:71-81. 1999
  3. ncbi request reprint Colonisation of the developing human brain and spinal cord by microglia: a review
    P Rezaie
    Department of Neuropathology, Institute of Psychiatry, De Crespigny Park, London SE5 8AF, United Kingdom
    Microsc Res Tech 45:359-82. 1999
  4. ncbi request reprint Expression of beta-chemokines and chemokine receptors in human fetal astrocyte and microglial co-cultures: potential role of chemokines in the developing CNS
    P Rezaie
    Department of Neuropathology, Institute of Psychiatry, King s College London, London, UK
    Glia 37:64-75. 2002
  5. ncbi request reprint Periventricular leukomalacia, inflammation and white matter lesions within the developing nervous system
    Payam Rezaie
    Department of Neuropathology, Institute of Psychiatry, King s College London, UK
    Neuropathology 22:106-32. 2002
  6. ncbi request reprint Subdural hematoma (SDH): assessment of macrophage reactivity within the dura mater and underlying hematoma
    S Al-Sarraj
    Department of Clinical Neuropathology, King s College, London, UK
    Clin Neuropathol 23:62-75. 2004
  7. ncbi request reprint In vitro expression of major histocompatibility class I and class II antigens by conditionally immortalized murine neural stem cells
    M Modo
    Neuroimaging Research Group Neurology P042, Institute of Psychiatry, De Crespigny Park, London SE5 8AF, UK
    Neurosci Lett 337:85-8. 2003
  8. ncbi request reprint Expression of adhesion molecules on human fetal cerebral vessels: relationship to microglial colonisation during development
    P Rezaie
    Department of Neuropathology, Institute of Psychiatry, London, UK
    Brain Res Dev Brain Res 104:175-89. 1997
  9. ncbi request reprint Microglia and the pathogenesis of spongiform encephalopathies
    P Rezaie
    Department of Neuropathology, Institute of Psychiatry, King's College London, DeCrespigny Park, SE5 8AF, London, UK
    Brain Res Brain Res Rev 35:55-72. 2001
  10. ncbi request reprint Late onset neurodegeneration in the Cln3-/- mouse model of juvenile neuronal ceroid lipofuscinosis is preceded by low level glial activation
    Charlie C Pontikis
    Pediatric Storage Disorders Laboratory, MRC Social Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, De Crespigny Park, King s College London, London, SE5 8AF, UK
    Brain Res 1023:231-42. 2004

Collaborators

Detail Information

Publications24

  1. ncbi request reprint Motility and ramification of human fetal microglia in culture: an investigation using time-lapse video microscopy and image analysis
    P Rezaie
    Department of Neuropathology, Institute of Psychiatry, King s College London, DeCrespigny Park, London, SE5 8AF, United Kingdom
    Exp Cell Res 274:68-82. 2002
    ..The interchangeable morphological continuum of microglia supports the view that these cells represent a single heterogeneous population of resident mononuclear phagocytes capable of marked plasticity...
  2. ncbi request reprint Microglia in the human fetal spinal cord--patterns of distribution, morphology and phenotype
    P Rezaie
    Department of Neuropathology, Institute of Psychiatry, De Crespigny Park, London SE5 8JN, UK
    Brain Res Dev Brain Res 115:71-81. 1999
    ..The patterns of microglial migration in human fetal cord differ from that within the cerebrum, but generally conform to a route following white to gray matter...
  3. ncbi request reprint Colonisation of the developing human brain and spinal cord by microglia: a review
    P Rezaie
    Department of Neuropathology, Institute of Psychiatry, De Crespigny Park, London SE5 8AF, United Kingdom
    Microsc Res Tech 45:359-82. 1999
    ..The need for specific cellular interactions and targeting is greater within the central nervous system than in other tissues. In this respect, microglia may additionally contribute towards CNS histogenesis...
  4. ncbi request reprint Expression of beta-chemokines and chemokine receptors in human fetal astrocyte and microglial co-cultures: potential role of chemokines in the developing CNS
    P Rezaie
    Department of Neuropathology, Institute of Psychiatry, King s College London, London, UK
    Glia 37:64-75. 2002
    ....
  5. ncbi request reprint Periventricular leukomalacia, inflammation and white matter lesions within the developing nervous system
    Payam Rezaie
    Department of Neuropathology, Institute of Psychiatry, King s College London, UK
    Neuropathology 22:106-32. 2002
    ..These findings provide the basis for clinical approaches targeted at protecting the premature brain from inflammatory damage, which may prove beneficial for treating PVL, if identified early in pathogenesis...
  6. ncbi request reprint Subdural hematoma (SDH): assessment of macrophage reactivity within the dura mater and underlying hematoma
    S Al-Sarraj
    Department of Clinical Neuropathology, King s College, London, UK
    Clin Neuropathol 23:62-75. 2004
    ..This study investigated the progressive and orderly pattern of reactivity of resident and infiltrating dural macrophages that occurs in response to injury associated with SDH...
  7. ncbi request reprint In vitro expression of major histocompatibility class I and class II antigens by conditionally immortalized murine neural stem cells
    M Modo
    Neuroimaging Research Group Neurology P042, Institute of Psychiatry, De Crespigny Park, London SE5 8AF, UK
    Neurosci Lett 337:85-8. 2003
    ..The downregulation of MHC antigens upon differentiation following cell transplantation could therefore contribute to the graft survival of MHP36 cells...
  8. ncbi request reprint Expression of adhesion molecules on human fetal cerebral vessels: relationship to microglial colonisation during development
    P Rezaie
    Department of Neuropathology, Institute of Psychiatry, London, UK
    Brain Res Dev Brain Res 104:175-89. 1997
    ..We conclude that fetal microglia usually occur at highly vascularised sites within the developing human fetal brain and are more specifically associated with the expression of ICAM-2 on cerebral endothelium...
  9. ncbi request reprint Microglia and the pathogenesis of spongiform encephalopathies
    P Rezaie
    Department of Neuropathology, Institute of Psychiatry, King's College London, DeCrespigny Park, SE5 8AF, London, UK
    Brain Res Brain Res Rev 35:55-72. 2001
    ..This article will review the roles of microglia in spongiform encephalopathies...
  10. ncbi request reprint Late onset neurodegeneration in the Cln3-/- mouse model of juvenile neuronal ceroid lipofuscinosis is preceded by low level glial activation
    Charlie C Pontikis
    Pediatric Storage Disorders Laboratory, MRC Social Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, De Crespigny Park, King s College London, London, SE5 8AF, UK
    Brain Res 1023:231-42. 2004
    ..These data provide evidence for subtle glial responses early in JNCL pathogenesis...
  11. ncbi request reprint Anomalous alterations affecting microglia in the central nervous system of a fetus at 12 weeks of gestation: case report
    Payam Rezaie
    Neuroembryonic Research Laboratory, Institute of Anatomy, University of Rostock, Gertrudenstrasse 9, 18055 Rostock, Germany
    Acta Neuropathol 107:176-80. 2004
    ....
  12. ncbi request reprint Excitotoxic lesioning of the rat basal forebrain with S-AMPA: consequent mineralization and associated glial response
    Alcyr Oliveira
    Department of Psychology, Institute of Psychiatry, King s College London, DeCrespigny Park, London, UK
    Exp Neurol 179:127-38. 2003
    ..The functional relevance of these findings is discussed...
  13. ncbi request reprint Mesoglia & microglia--a historical review of the concept of mononuclear phagocytes within the central nervous system
    Payam Rezaie
    Department of Neuropathology, Institute of Psychiatry, SE5 8AF, UK
    J Hist Neurosci 11:325-74. 2002
    ..This paper will present a comprehensive overview of the pioneering research on mononuclear phagocytes within the central nervous system, which has direct bearing on our present-day understanding of the concept of microglia...
  14. ncbi request reprint Transplantation of neural stem cells in a rat model of stroke: assessment of short-term graft survival and acute host immunological response
    Michel Modo
    Neuroimaging Research Group Neurology P042, Institute of Psychiatry, De Crespigny Park, London SE5 8AF, UK
    Brain Res 958:70-82. 2002
    ..These results provide evidence for the low immunogenic properties of MHP36 cells during the initial period following implantation, known to be associated with an acute host immune response and ensuing graft rejection...
  15. ncbi request reprint Glial activation spreads from specific cerebral foci and precedes neurodegeneration in presymptomatic ovine neuronal ceroid lipofuscinosis (CLN6)
    Manfred J Oswald
    Agriculture and Life Sciences Division, Lincoln University, PO Box 84, Canterbury, New Zealand
    Neurobiol Dis 20:49-63. 2005
    ..These data support suggestions that neurodegeneration and storage body accumulation may be independent manifestations of CLN6 mutation and indicate that glial cell activation may be an important mediator in pathogenesis...
  16. ncbi request reprint Vacuolar degeneration affecting brain macrophages/microglia in variant CJD: a report on two cases
    Payam Rezaie
    Department of Biological Sciences, Faculty of Science, The Open University, Milton Keynes, MK7 6AA, UK
    Acta Neuropathol 114:651-8. 2007
    ..This type of vacuolation may constitute a component of the overall profile of spongiform changes associated with vCJD...
  17. ncbi request reprint Progressive CAG expansion in the brain of a novel R6/1-89Q mouse model of Huntington's disease with delayed phenotypic onset
    Sarat C Vatsavayai
    Huntington s Disease Research Forum, Department of Biological Sciences, The Open University, Walton Hall, Milton Keynes, UK
    Brain Res Bull 72:98-102. 2007
    ..This novel line shares a common genetic ancestry with R6/1, differing only in CAG repeat number, and therefore, provides an additional tool with which to examine early molecular and neurophysiological changes in HD...
  18. ncbi request reprint Activation of non-neuronal cells within the prenatal developing brain of sheep with neuronal ceroid lipofuscinosis
    Graham W Kay
    Agriculture and Life Sciences Division, Lincoln University, Canterbury, New Zealand
    Brain Pathol 16:110-6. 2006
    ..This prenatal activation of non-neuronal cells within the affected brain indicates the onset of pathogenesis during brain development and that an ordered sequence of glial activation precedes neurodegeneration...
  19. ncbi request reprint Early development of aberrant synaptic plasticity in a mouse model of Huntington's disease
    Austen J Milnerwood
    Huntington s Disease Research Forum, The Open University, Milton Keynes, UK
    Hum Mol Genet 15:1690-703. 2006
    ..We present the first detailed description of a progressive derailment of a functional neural correlate of cognitive processing in HD...
  20. ncbi request reprint Expression of cellular prion protein in the frontal and occipital lobe in Alzheimer's disease, diffuse Lewy body disease, and in normal brain: an immunohistochemical study
    Payam Rezaie
    Department of Biological Sciences, Faculty of Science, The Open University, Walton Hall, Milton Keynes MK7 6AA, United Kingdom
    J Histochem Cytochem 53:929-40. 2005
    ..In conclusion, this study supports the proposal that regional changes in expression of PrP(c) may occur in certain neurodegenerative disorders such as AD, but not in other disorders such as DLBD...
  21. ncbi request reprint Microglia in the cerebral wall of the human telencephalon at second trimester
    Payam Rezaie
    Department of Biological Sciences, Faculty of Science, The Open University, Walton Hall, Milton Keynes, MK7 6AA, UK
    Cereb Cortex 15:938-49. 2005
    ..These findings are discussed in relation to developmental events that take place during the second trimester within the wall of the telencephalon...
  22. ncbi request reprint Brain macrophages and microglia in human fetal hydrocephalus
    Norbert Ulfig
    Neuroembryonic Research Laboratory, Institute of Anatomy, University of Rostock, Gertrudenstrasse 9, D 18055 Rostock, Germany
    Brain Dev 26:307-15. 2004
    ..The macrophage response detected at the ependymal lining of the ventricles and within the periventricular area in hydrocephalus may be related both to the severity of hydrocephalus and the age of the fetus...
  23. pmc Hippocampal neuron loss exceeds amyloid plaque load in a transgenic mouse model of Alzheimer's disease
    Christoph Schmitz
    Department of Psychiatry and Neuropsychology, Division of Cellular Neuroscience, University of Maastricht, Maastricht, The Netherlands
    Am J Pathol 164:1495-502. 2004
    ..These findings point to the potential involvement of more than one mechanism in hippocampal neuron loss in this APP/PS-1 double-transgenic mouse model of Alzheimer's disease...
  24. ncbi request reprint Differential activation of mononuclear phagocytes in cerebellar malformation associated with Walker-Warburg syndrome
    Norbert Ulfig
    Neuroembryonic Research Laboratory, Institute of Anatomy, University of Rostock, Rostock, Germany
    Neuropathology 28:333-40. 2008
    ..In this case report, we present evidence for focal and differential activation of mononuclear phagocytes specifically confined to the dysplastic cerebellum of an infant at 5 months of age, diagnosed with WWS...