Martin J Prince

..We aimed to develop and test a culturally and educationally unbiased diagnostic instrument for dementia...

..Based on previous research, hypotheses focused on carer sex, care inputs, behavioural and psychological symptoms (BPSD) and socioeconomic status, together with potential buffering effects of informal support and employing paid carers...

..The aim of this study was to investigate the independent and interactive effects of these maternal exposures upon neonatal outcomes among pregnant adolescents in a disadvantaged population from Sao Paulo, Brazil...

..Demographic ageing, and the health transition will soon lead to large increases in the number of dependent older people in low and middle income countries. Despite its importance, this topic has not previously been studied...

..Aim of this study was to identify opinions and views of the members serving in ethical review and ethics committees in Sri Lanka on informed consent, essential components in the information leaflet and the consent form...

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..The 10/66 Dementia Research Group sought to do this using assessments from their one phase dementia diagnostic research interview, and to validate the resulting algorithm in a population-based study in Cuba...

..The purpose of this article is to review the procedures to establish measurement validity in cross-cultural comparative research, including recent developments in the quantitative assessment of cross-cultural construct validity...

..The Geriatric Mental State (GMS) is the most widely used psychiatric research assessment for older persons. Evidence for validity comes from the developed world...

..Mental health awareness needs to be integrated into all aspects of health and social policy, health-system planning, and delivery of primary and secondary general health care...

..Adult head circumference is an indicator of brain growth. There is a limited literature linking short legs and small skulls to an increased risk for cognitive impairment and dementia in late life...

..We aimed to derive a brief version of cognitive and informant scales from the Community Screening Instrument for Dementia (CSI-D) and to carry out initial assessments of their likely validity...

..This paper describes the protocols for the 10/66 population-based and intervention studies that aim to redress this imbalance...

..Rapid demographic ageing will soon lead to large increases in the numbers of persons with dementia in developing countries. This study is the first comprehensive assessment of care arrangements for people with dementia in those regions...

..It represents a collaboration of academics, clinicians, and an international non-governmental organization, Alzheimer's Disease International (ADI)...

..The authors investigated the prevalence of self-reported stroke, stroke-related disability, dependence and care-giver strain in Latin America (LA), China and India...

..In Europe, the effects of better education and home ownership upon mortality seem to persist into old age, but these effects may not generalise to LMICs. Reliable data on causes and determinants of mortality are lacking...

..More work is needed to assess the generalizability of our findings to different populations...

..Evidence of an association between fish and meat consumption and risk of dementia is inconsistent and nonexistent in populations in developing countries...

..Using a standard protocol, we aim to assess the association of fish consumption and late-life depression in seven low- and middle-income countries...

..Aetiological mechanisms underlying ethnic density associations with psychosis remain unclear...

..To describe patterns of recent health service utilisation, and consequent out-of-pocket expenses among older people in countries with low and middle incomes, and to assess the equity with which services are accessed and delivered...

..To estimate the prevalence, social patterning, treatment and control of hypertension among older people in the 10/66 Dementia Research Group developing country sites...

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..We studied these among people aged 65 years and over living in urban catchment areas in Chennai, south India...

..Given an important independent contribution of anaemia to disability, more research is needed to identify preventable and treatable causes...

..Allocation to the urgent list appears to be based primarily on the patient's age, but is partially influenced by patient's better physical health and viewing treatment as being effective...

..A ROC curve analysis showed an area under the curve > 0.70 for all scores. The choice of optimal cutoffs for the Urdu version is discussed...

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..Yet, to date, no studies have used psychiatric diagnostic assessment to identify common forms of mental distress among survivors returning to their home country...

..9-6.7) compared to those with ID/II genotype (odds ratio 0.7, 95% CI 0.4-1.2). This interaction was particularly strong for decline in verbal memory and was not apparently mediated by vascular risk factors measured at baseline...

..We aimed to assess the contribution of physical, mental, and cognitive chronic diseases to disability, and the extent to which sociodemographic and health characteristics account for geographical variation in disability...

..The proportion of the global population aged 60 and over is increasing, more so in Latin America than any other region. Depression is common among elderly people and an important cause of disability worldwide...

..To study the epidemiological evidence on the prevalence of exposure to violence and its relationship with mental health problems in low and middle-income countries...

..Two-phase diagnostic surveys are popular in psychiatric epidemiology. The Geriatric Depression Scale (GDS) and the General Health Questionnaire (GHQ) are commonly used to screen in older and younger populations, respectively...

..Although antenatal mental distress may be self-limiting for many women, in those with enduring life difficulties, including poverty and abusive relationships, poor maternal mental health may persist...

..As a part of a larger study on ethics and informed consent in Sri Lanka, this study aimed to ascertain the level of understanding of 'research' by exploring the views of the public and professionals...

..To investigate the association between observer-rated quality of internal accommodation and risk of onset of depression...

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..To investigate associations between baseline factors and subsequent cognitive decline in an older African-Caribbean population...

..To assess the concurrent and the construct validity of the Alcohol Use Disorders Identification Test (AUDIT) in an urban Brazilian sample...

..In low- and middle-income countries (LAMICs), perinatal CMD is inconsistently associated with infant development, but the impact of severity and persistence has not been examined...

..Traditional perinatal practices may protect against postnatal common mental disorders (CMD) in non-Western societies...

..The results from the present study therefore validated the four mental health measures as being predictive of psychiatric caseness...

..As the population samples are likely to be different from clinic samples it is necessary to test the validity again in a community sample before confirming the validity of the modified interview schedule...

..However dependence is much less studied although intrinsically linked to disability. We investigated the prevalence and correlates of dependence among older people from middle income countries...

..It has been suggested that rural-urban migration will have adverse consequences for older parents left behind...

..There is a dearth of methodological studies critically evaluating reliability, validity and feasibility of measures of common mental disorders (CMD) in low-income countries...

..Minor depressive disorder seems to be a useful and valid diagnostic construct with particular clinical significance in this and, possibly, similar developing country settings...

..Life events (LEs) are recognised to be important risk factors for common mental disorders (CMD). Their prominence may vary across age groups but this issue has received little systematic investigation...

..Evidence on the utility of the minor depressive disorder diagnostic construct in rural communities and developing countries is scarce...

..The objective of this study is to investigate, in a relatively homogeneous population, the effects of patient's psychological distress and illness beliefs upon GP's requests for urgent outpatient assessment...

..The cultural validity of instruments to detect perinatal common mental disorders (CMD) in rural, community settings has been little-investigated in developing countries...

..We aimed to develop a conceptual framework of HRQL in dementia from the perspective of people with dementia and their carers and to examine differences in the reports of the HRQL of these two groups...

..This study aimed to determine to what extent ERC approval and informed consent procedures are documented in locally and internationally published human subject research carried out in Sri Lanka...

..The public health significance of mixed anxiety-depressive disorder (MADD) and the distinctiveness of its phenomenology have yet to be established...

..100 years after the first description, Alzheimer's disease is one of the most disabling and burdensome health conditions worldwide. We used the Delphi consensus method to determine dementia prevalence for each world region...

..To examine the impact of antenatal psychosocial stressors, including maternal common mental disorders (CMD), upon low birth weight, stillbirth and neonatal mortality, and other perinatal outcomes in rural Ethiopia...

..The outcome and impact of major depression in developing countries are not clear...

..Our aim was to elicit the illness perceptions of patients with MUS in Sri Lankan primary care to modify and improve a CBT intervention...

..International funding agencies, academics, and other bodies need to address sustaining such initiatives as priorities in reducing scarcity and inequity in mental health research in developing countries...

..Finally, to determine if any protective ethnic density effects are mediated by reduced exposure to racism and improved social support...

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..Results provide a set of range estimates for mental health resource planning and evaluation in a variety of developing regions...

..We consider the potential for epidemiological research to raise awareness, refine the policy agenda, and promote action, using the example of the dissemination strategy developed by the 10/66 Dementia Research Group...

..To investigate the association between subjective memory deficit (SMD) and cognitive impairment in a community population and modification of this association by level of social activity...

..Mental capacity has been little studied among older general hospital inpatients...

..The authors aimed to establish obsessive-compulsive disorder prevalence and its clinical typology among adults in private households in Great Britain and to obtain generalizable estimates of impairment and help-seeking...

..2) around 64 cM (43-70 cM) near marker D1S2892 and another on chromosome 6p (LOD 2.7) around 47 cM (34-63 cM) near marker D6S1610. Further exploratory sex-specific analyses suggested that these QTLs might have sex-limited effects...

..To investigate inpatient mortality and the use of invasive diagnostic and revascularization procedures after acute myocardial infarction (AMI) in people with schizophrenia and bipolar disorder...

..We analysed the prevalence of screen positive personality disorder in a representative sample of adults with OCD living in private households in the UK...

..The Affective Suffering sub-component had more robust cross-cultural validity than the Motivation sub-component...

..Lack of insight has been observed in people with schizophrenia across cultures but assessment of insight must take into account prevailing illness models...

..The authors asked whether polymorphic variation at three genes related to vascular disease, and other vascular disease risk factors, determine late-life depression...

..However, data on treatment seeking from community samples are scant. This study analyzed service use by adults with OCD living in private households in Great Britain...