Simon C Pitchford

Summary

Affiliation: King's College London
Country: UK

Publications

  1. ncbi VEGFR1 stimulates a CXCR4-dependent translocation of megakaryocytes to the vascular niche, enhancing platelet production in mice
    Simon C Pitchford
    Leukocyte Biology Section, National Heart and Lung Institute, Imperial College, London, UK
    Blood 120:2787-95. 2012
  2. ncbi Troubleshooting: Quantification of mobilization of progenitor cell subsets from bone marrow in vivo
    Simon C Pitchford
    Sackler Institute of Pulmonary Pharmacology, Division of Pharmaceutical Sciences, King s College London, SE1 9NH, UK
    J Pharmacol Toxicol Methods 61:113-21. 2010
  3. ncbi Platelets are necessary for airway wall remodeling in a murine model of chronic allergic inflammation
    Simon C Pitchford
    Sackler Institute of Pulmonary Pharmacology, 5th Fl, Hodgkin Bldg, Guy s Campus, King s College London, London SE1 1UL, United Kingdom
    Blood 103:639-47. 2004
  4. ncbi Differential mobilization of subsets of progenitor cells from the bone marrow
    Simon C Pitchford
    Leukocyte Biology Section, National Heart and Lung Institute, Imperial College, London SW7 2AZ, UK
    Cell Stem Cell 4:62-72. 2009
  5. ncbi CXCR2 mediates the recruitment of endothelial progenitor cells during allergic airways remodeling
    Carla P Jones
    Leukocyte Biology Section, National Heart and Lung Institute, Imperial College London, United Kingdom
    Stem Cells 27:3074-81. 2009
  6. ncbi Circulating platelet-neutrophil complexes are important for subsequent neutrophil activation and migration
    Kristin N Kornerup
    Sackler Institute of Pulmonary Pharmacology and Therapeutics, Division of Pharmaceutical Sciences, School of Biomedical and Health Sciences, King s College, London, UK
    J Appl Physiol 109:758-67. 2010
  7. ncbi The coordinated action of G-CSF and ELR + CXC chemokines in neutrophil mobilization during acute inflammation
    Antje M Wengner
    Leukocyte Biology Section, National Heart and Lung Institute, Faculty of Medicine, Imperial College London, London, United Kingdom
    Blood 111:42-9. 2008
  8. ncbi Combinatorial stem cell mobilization in animal models
    Simon C Pitchford
    Leukocyte Biology Section, Faculty of Medicine National Heart and Lung Institute, Imperial College London, London, UK
    Methods Mol Biol 904:139-54. 2012
  9. ncbi Real-time measurement of non-lethal platelet thromboembolic responses in the anaesthetized mouse
    Charalambos Tymvios
    Sir Alexander Fleming Building, National Heart and Lung Institute, Imperial College London, Exhibition Road, London, UK
    Thromb Haemost 99:435-40. 2008
  10. ncbi Platelets are essential for leukocyte recruitment in allergic inflammation
    Simon C Pitchford
    Sackler Institute of Pulmonary Pharmacology, GKT School of Biomedical Sciences, King's College London, London
    J Allergy Clin Immunol 112:109-18. 2003

Collaborators

Detail Information

Publications10

  1. ncbi VEGFR1 stimulates a CXCR4-dependent translocation of megakaryocytes to the vascular niche, enhancing platelet production in mice
    Simon C Pitchford
    Leukocyte Biology Section, National Heart and Lung Institute, Imperial College, London, UK
    Blood 120:2787-95. 2012
    ....
  2. ncbi Troubleshooting: Quantification of mobilization of progenitor cell subsets from bone marrow in vivo
    Simon C Pitchford
    Sackler Institute of Pulmonary Pharmacology, Division of Pharmaceutical Sciences, King s College London, SE1 9NH, UK
    J Pharmacol Toxicol Methods 61:113-21. 2010
    ....
  3. ncbi Platelets are necessary for airway wall remodeling in a murine model of chronic allergic inflammation
    Simon C Pitchford
    Sackler Institute of Pulmonary Pharmacology, 5th Fl, Hodgkin Bldg, Guy s Campus, King s College London, London SE1 1UL, United Kingdom
    Blood 103:639-47. 2004
    ..Neither platelet depletion nor dexamethasone administration inhibited chronic AHR; thus, mechanisms other than inflammation and airway remodeling may be involved in the pathogenesis of chronic AHR...
  4. ncbi Differential mobilization of subsets of progenitor cells from the bone marrow
    Simon C Pitchford
    Leukocyte Biology Section, National Heart and Lung Institute, Imperial College, London SW7 2AZ, UK
    Cell Stem Cell 4:62-72. 2009
    ..These findings may inform studies investigating mechanisms that regulate progenitor cell recruitment in disease and can be exploited to provide efficacious stem cell therapy for tissue regeneration...
  5. ncbi CXCR2 mediates the recruitment of endothelial progenitor cells during allergic airways remodeling
    Carla P Jones
    Leukocyte Biology Section, National Heart and Lung Institute, Imperial College London, United Kingdom
    Stem Cells 27:3074-81. 2009
    ..The data presented here provide in vivo evidence that CXCR2 is critical for both EPC recruitment and the angiogenic response in this model of allergic inflammation of the airways...
  6. ncbi Circulating platelet-neutrophil complexes are important for subsequent neutrophil activation and migration
    Kristin N Kornerup
    Sackler Institute of Pulmonary Pharmacology and Therapeutics, Division of Pharmaceutical Sciences, School of Biomedical and Health Sciences, King s College, London, UK
    J Appl Physiol 109:758-67. 2010
    ..Targeting this interaction may be a successful strategy for inflammatory conditions where current therapy fails to provide adequate treatment...
  7. ncbi The coordinated action of G-CSF and ELR + CXC chemokines in neutrophil mobilization during acute inflammation
    Antje M Wengner
    Leukocyte Biology Section, National Heart and Lung Institute, Faculty of Medicine, Imperial College London, London, United Kingdom
    Blood 111:42-9. 2008
    ..8 x 10(6) and 5.4 x 10(6) neutrophils, respectively, while the infusion of KC and G-CSF together mobilized 19.5 x 10(6) neutrophils, indicating that these factors act cooperatively with respect to neutrophil mobilization...
  8. ncbi Combinatorial stem cell mobilization in animal models
    Simon C Pitchford
    Leukocyte Biology Section, Faculty of Medicine National Heart and Lung Institute, Imperial College London, London, UK
    Methods Mol Biol 904:139-54. 2012
    ..Identification of such novel pharmacological regimens that stimulate the selective mobilization of EPCs and MSCs might be exploited in the future for tissue regeneration...
  9. ncbi Real-time measurement of non-lethal platelet thromboembolic responses in the anaesthetized mouse
    Charalambos Tymvios
    Sir Alexander Fleming Building, National Heart and Lung Institute, Imperial College London, Exhibition Road, London, UK
    Thromb Haemost 99:435-40. 2008
    ....
  10. ncbi Platelets are essential for leukocyte recruitment in allergic inflammation
    Simon C Pitchford
    Sackler Institute of Pulmonary Pharmacology, GKT School of Biomedical Sciences, King's College London, London
    J Allergy Clin Immunol 112:109-18. 2003
    ..CONCLUSION: These results suggest that platelet participation in cell recruitment occurs at the level of the circulation and might involve the priming of leukocytes for subsequent adhesion and transmigration into tissues...