Nader Perroud

Summary

Affiliation: King's College London
Country: UK

Publications

  1. ncbi Genetic predictors of increase in suicidal ideation during antidepressant treatment in the GENDEP project
    Nader Perroud
    MRC Social Genetic and Developmental Psychiatry Center, Institute of Psychiatry, King s College Lodon, London, UK
    Neuropsychopharmacology 34:2517-28. 2009
  2. doi Genome-wide pharmacogenetics of antidepressant response in the GENDEP project
    Rudolf Uher
    Medical Research Council Social, Genetic, and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, SE5 8AF, London, United Kingdom
    Am J Psychiatry 167:555-64. 2010
  3. ncbi Genetic predictors of response to antidepressants in the GENDEP project
    Rudolf Uher
    MRC Social Genetic and Developmental Psychiatry Center, Institute of Psychiatry, King s College London, London, UK
    Pharmacogenomics J 9:225-33. 2009
  4. ncbi Moderation of antidepressant response by the serotonin transporter gene
    Patricia Huezo-Diaz
    Institute of Psychiatry, King s College London, UK
    Br J Psychiatry 195:30-8. 2009
  5. doi CYP2C19 genotype predicts steady state escitalopram concentration in GENDEP
    Patricia Huezo-Diaz
    MRC SGDP Centre, Institute of Psychiatry at King s College London, London, UK
    J Psychopharmacol 26:398-407. 2012
  6. doi Adverse reactions to antidepressants
    Rudolf Uher
    P080 SGDP, Institute of Psychiatry, King s College London, London SE5 8AF, UK
    Br J Psychiatry 195:202-10. 2009
  7. pmc Genetic predictors of response to serotonergic and noradrenergic antidepressants in major depressive disorder: a genome-wide analysis of individual-level data and a meta-analysis
    Katherine E Tansey
    Institute of Psychiatry, King s College London, London, UK
    PLoS Med 9:e1001326. 2012
  8. ncbi Genetic relationships between suicide attempts, suicidal ideation and major psychiatric disorders: A genome-wide association and polygenic scoring study
    Niamh Mullins
    MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, London, United Kingdom
    Am J Med Genet B Neuropsychiatr Genet 165:428-37. 2014
  9. pmc Genomewide association scan of suicidal thoughts and behaviour in major depression
    Alexandra Schosser
    MRC Social Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, London, United Kingdom
    PLoS ONE 6:e20690. 2011
  10. doi Body weight as a predictor of antidepressant efficacy in the GENDEP project
    Rudolf Uher
    Institute of Psychiatry, King s College London, United Kingdom
    J Affect Disord 118:147-54. 2009

Detail Information

Publications11

  1. ncbi Genetic predictors of increase in suicidal ideation during antidepressant treatment in the GENDEP project
    Nader Perroud
    MRC Social Genetic and Developmental Psychiatry Center, Institute of Psychiatry, King s College Lodon, London, UK
    Neuropsychopharmacology 34:2517-28. 2009
    ..Among men, genetic variation in noradrenergic signaling may interact with norepinephrine reuptake-inhibiting antidepressants, thereby contributing to suicidality...
  2. doi Genome-wide pharmacogenetics of antidepressant response in the GENDEP project
    Rudolf Uher
    Medical Research Council Social, Genetic, and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, SE5 8AF, London, United Kingdom
    Am J Psychiatry 167:555-64. 2010
    ..The authors performed a genome-wide association analysis of improvement of depression severity with two antidepressant drugs...
  3. ncbi Genetic predictors of response to antidepressants in the GENDEP project
    Rudolf Uher
    MRC Social Genetic and Developmental Psychiatry Center, Institute of Psychiatry, King s College London, London, UK
    Pharmacogenomics J 9:225-33. 2009
    ..The single marker associations explained only a small proportion of variance in response to antidepressants, indicating a need for a multivariate approach to prediction...
  4. ncbi Moderation of antidepressant response by the serotonin transporter gene
    Patricia Huezo-Diaz
    Institute of Psychiatry, King s College London, UK
    Br J Psychiatry 195:30-8. 2009
    ..We hypothesised that the pharmacogenetic effect of 5-HTTLPR is modulated by gender, age and other variants in the serotonin transporter gene...
  5. doi CYP2C19 genotype predicts steady state escitalopram concentration in GENDEP
    Patricia Huezo-Diaz
    MRC SGDP Centre, Institute of Psychiatry at King s College London, London, UK
    J Psychopharmacol 26:398-407. 2012
    ..0003; p = 0.0012 Bonferroni corrected). In conclusion, we have demonstrated an association between CYP2C19 genotype, including the CYP2C19*17 allele, and steady state escitalopram concentration...
  6. doi Adverse reactions to antidepressants
    Rudolf Uher
    P080 SGDP, Institute of Psychiatry, King s College London, London SE5 8AF, UK
    Br J Psychiatry 195:202-10. 2009
    ..Adverse drug reactions are important determinants of non-adherence to antidepressant treatment, but their assessment is complicated by overlap with depressive symptoms and lack of reliable self-report measures...
  7. pmc Genetic predictors of response to serotonergic and noradrenergic antidepressants in major depressive disorder: a genome-wide analysis of individual-level data and a meta-analysis
    Katherine E Tansey
    Institute of Psychiatry, King s College London, London, UK
    PLoS Med 9:e1001326. 2012
    ..This study aims to test the hypothesis that common genetic variants can predict response to antidepressants in a clinically meaningful way...
  8. ncbi Genetic relationships between suicide attempts, suicidal ideation and major psychiatric disorders: A genome-wide association and polygenic scoring study
    Niamh Mullins
    MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, London, United Kingdom
    Am J Med Genet B Neuropsychiatr Genet 165:428-37. 2014
    ..Polygenic score analysis suggests pleiotropy between psychiatric disorders and suicidal ideation whereas the tendency to act on such thoughts may have a partially independent genetic diathesis. © 2014 Wiley Periodicals, Inc. ..
  9. pmc Genomewide association scan of suicidal thoughts and behaviour in major depression
    Alexandra Schosser
    MRC Social Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, London, United Kingdom
    PLoS ONE 6:e20690. 2011
    ..Suicidal behaviour can be conceptualised as a continuum from suicidal ideation, to suicidal attempts to completed suicide. In this study we identify genes contributing to suicidal behaviour in the depression study RADIANT...
  10. doi Body weight as a predictor of antidepressant efficacy in the GENDEP project
    Rudolf Uher
    Institute of Psychiatry, King s College London, United Kingdom
    J Affect Disord 118:147-54. 2009
    ..The present report explores the moderation of antidepressant response by body weight to establish the specificity to antidepressant mode of action, type of depressive symptoms and gender...
  11. doi Prevalence and heritability of compulsive hoarding: a twin study
    Alessandra C Iervolino
    Department of Psychology, King s College London, Institute of Psychiatry, London SE5 8AF, UK
    Am J Psychiatry 166:1156-61. 2009
    ..It appears to be highly prevalent and to run in families. However, this familiality could be due to genetic or environmental factors. This study examined the prevalence and heritability of compulsive hoarding in a large sample of twins...