José L Orgaz

Summary

Affiliation: King's College London
Country: UK

Publications

  1. pmc Changes in the gene expression profile of A375 human melanoma cells induced by overexpression of multifunctional pigment epithelium-derived factor
    José L Orgaz
    Department of Biochemistry, Universidad Autónoma de Madrid UAM and Instituto de Investigaciones Biomédicas Alberto Sols, CSIC UAM, Madrid, Spain
    Melanoma Res 21:285-97. 2011
  2. doi request reprint (V600E)BRAF promotes invasiveness of thyroid cancer cells by decreasing E-cadherin expression through a Snail-dependent mechanism
    Pablo Baquero
    Departamento de Bioquimica y Biologia Molecular, Facultad de Medicina, Universidad de Alcala, Madrid, Spain
    Cancer Lett 335:232-41. 2013

Collaborators

  • Omar Ladhani
  • Pablo Baquero
  • Benilde Jimenez
  • Eva Jiménez-Mora
  • Antonio Chiloeches
  • Irene Sánchez-Hernández

Detail Information

Publications2

  1. pmc Changes in the gene expression profile of A375 human melanoma cells induced by overexpression of multifunctional pigment epithelium-derived factor
    José L Orgaz
    Department of Biochemistry, Universidad Autónoma de Madrid UAM and Instituto de Investigaciones Biomédicas Alberto Sols, CSIC UAM, Madrid, Spain
    Melanoma Res 21:285-97. 2011
    ..Our study identifies new molecular targets and signaling pathways that may potentially contribute to determine PEDF's ability to restrict the aggressiveness of A375 human melanoma cells...
  2. doi request reprint (V600E)BRAF promotes invasiveness of thyroid cancer cells by decreasing E-cadherin expression through a Snail-dependent mechanism
    Pablo Baquero
    Departamento de Bioquimica y Biologia Molecular, Facultad de Medicina, Universidad de Alcala, Madrid, Spain
    Cancer Lett 335:232-41. 2013
    ..These results reveal a novel (V600E)BRAF-induced mechanism in thyroid tumours progression and provides a rationale for using the PLX4720 inhibitor to target (V600E)BRAF signalling to effectively control progression of thyroid cancer...