Robin M Murray

Summary

Affiliation: King's College London
Country: UK

Publications

  1. ncbi request reprint Cannabis, the mind and society: the hash realities
    Robin M Murray
    Institute of Psychiatry, Psychological Medicine, De Crespigny Park, Denmark Hill, London, SE5 8AF, UK
    Nat Rev Neurosci 8:885-95. 2007
  2. doi request reprint Schizophrenia: from developmental deviance to dopamine dysregulation
    Robin M Murray
    Institute of Psychiatry, De Crespigny Park, London, United Kingdom
    Eur Neuropsychopharmacol 18:S129-34. 2008
  3. ncbi request reprint A developmental model for similarities and dissimilarities between schizophrenia and bipolar disorder
    Robin M Murray
    Institute of Psychiatry, Psychological Medicine, Denmark Hill, DeCrespigny Park, London SE5 8AF, UK
    Schizophr Res 71:405-16. 2004
  4. ncbi request reprint Substantial shared genetic influences on schizophrenia and event-related potentials
    Mei Hua Hall
    Social, Genetic, and Developmental Psychiatry Research Centre, Division of Psychological Medicine, Institute of Psychiatry, King s College London, UK, and the Psychology Research Laboratory, McLean Hospital, Belmont, MA, USA
    Am J Psychiatry 164:804-12. 2007
  5. doi request reprint Altered effect of dopamine transporter 3'UTR VNTR genotype on prefrontal and striatal function in schizophrenia
    Diana P Prata
    Division of Psychological Medicine and Psychiatry, Institute of Psychiatry, King s College London, PO67, De Crespigny Park, London SE5 8AF, England
    Arch Gen Psychiatry 66:1162-72. 2009
  6. doi request reprint Neurological abnormalities and cognitive ability in first-episode psychosis
    Paola Dazzan
    Department of Psychiatry, Box 63, Institute of Psychiatry, De Crespigny Park, London SE5 8AF, UK
    Br J Psychiatry 193:197-202. 2008
  7. ncbi request reprint Duration of untreated psychosis and neuropsychological function in first episode psychosis
    Julia M Lappin
    Kings College Hospital Institute of Psychiatry, Division of Psychological Medicine, PO63, De Crespigny Park, Denmark Hill, London, SE5 8AF, UK
    Schizophr Res 95:103-10. 2007
  8. doi request reprint Preterm birth and psychiatric disorders in young adult life
    Chiara Nosarti
    Department of Psychosis Studies, Institute of Psychiatry, King s Health Partners, King s College London, London, UK
    Arch Gen Psychiatry 69:E1-8. 2012
  9. ncbi request reprint Regional brain morphometry in patients with schizophrenia or bipolar disorder and their unaffected relatives
    Colm McDonald
    Division of Psychological Medicine, Institute of Psychiatry, London, UK
    Am J Psychiatry 163:478-87. 2006
  10. doi request reprint Specific and generalized neuropsychological deficits: a comparison of patients with various first-episode psychosis presentations
    Jolanta Zanelli
    Institute of Psychiatry, PO63, Division of Psychological Medicine and Psychiatry, De Crespigny Park, Denmark Hill, London SE5 8AF, UK
    Am J Psychiatry 167:78-85. 2010

Detail Information

Publications128 found, 100 shown here

  1. ncbi request reprint Cannabis, the mind and society: the hash realities
    Robin M Murray
    Institute of Psychiatry, Psychological Medicine, De Crespigny Park, Denmark Hill, London, SE5 8AF, UK
    Nat Rev Neurosci 8:885-95. 2007
    ....
  2. doi request reprint Schizophrenia: from developmental deviance to dopamine dysregulation
    Robin M Murray
    Institute of Psychiatry, De Crespigny Park, London, United Kingdom
    Eur Neuropsychopharmacol 18:S129-34. 2008
    ..Finally, the two theories are beginning to be integrated through the growing evidence that all the developmental risk factors which increase risk of schizophrenia appear to act by facilitating dopamine dysregulation...
  3. ncbi request reprint A developmental model for similarities and dissimilarities between schizophrenia and bipolar disorder
    Robin M Murray
    Institute of Psychiatry, Psychological Medicine, Denmark Hill, DeCrespigny Park, London SE5 8AF, UK
    Schizophr Res 71:405-16. 2004
    ....
  4. ncbi request reprint Substantial shared genetic influences on schizophrenia and event-related potentials
    Mei Hua Hall
    Social, Genetic, and Developmental Psychiatry Research Centre, Division of Psychological Medicine, Institute of Psychiatry, King s College London, UK, and the Psychology Research Laboratory, McLean Hospital, Belmont, MA, USA
    Am J Psychiatry 164:804-12. 2007
    ..The present study used a twin design to estimate the extent of genetic overlap between these indices and the liability to schizophrenia...
  5. doi request reprint Altered effect of dopamine transporter 3'UTR VNTR genotype on prefrontal and striatal function in schizophrenia
    Diana P Prata
    Division of Psychological Medicine and Psychiatry, Institute of Psychiatry, King s College London, PO67, De Crespigny Park, London SE5 8AF, England
    Arch Gen Psychiatry 66:1162-72. 2009
    ..The dopamine transporter plays a key role in the regulation of central dopaminergic transmission, which modulates cognitive processing. Disrupted dopamine function and impaired executive processing are robust features of schizophrenia...
  6. doi request reprint Neurological abnormalities and cognitive ability in first-episode psychosis
    Paola Dazzan
    Department of Psychiatry, Box 63, Institute of Psychiatry, De Crespigny Park, London SE5 8AF, UK
    Br J Psychiatry 193:197-202. 2008
    ....
  7. ncbi request reprint Duration of untreated psychosis and neuropsychological function in first episode psychosis
    Julia M Lappin
    Kings College Hospital Institute of Psychiatry, Division of Psychological Medicine, PO63, De Crespigny Park, Denmark Hill, London, SE5 8AF, UK
    Schizophr Res 95:103-10. 2007
    ..We predicted that longer DUP would be associated with greater neurocognitive impairment...
  8. doi request reprint Preterm birth and psychiatric disorders in young adult life
    Chiara Nosarti
    Department of Psychosis Studies, Institute of Psychiatry, King s Health Partners, King s College London, London, UK
    Arch Gen Psychiatry 69:E1-8. 2012
    ..It is unclear whether these associations pertain to other adult-onset psychiatric disorders and whether these perinatal events are independent...
  9. ncbi request reprint Regional brain morphometry in patients with schizophrenia or bipolar disorder and their unaffected relatives
    Colm McDonald
    Division of Psychological Medicine, Institute of Psychiatry, London, UK
    Am J Psychiatry 163:478-87. 2006
    ..The authors used region-of-interest morphometry to volumetrically assess brain structures frequently implicated in psychotic illness in families affected with schizophrenia or psychotic bipolar disorder...
  10. doi request reprint Specific and generalized neuropsychological deficits: a comparison of patients with various first-episode psychosis presentations
    Jolanta Zanelli
    Institute of Psychiatry, PO63, Division of Psychological Medicine and Psychiatry, De Crespigny Park, Denmark Hill, London SE5 8AF, UK
    Am J Psychiatry 167:78-85. 2010
    ..In the context of four distinct diagnostic groups, the authors compared neuropsychological performance among patients experiencing their first psychotic episode...
  11. doi request reprint Opposite effects of catechol-O-methyltransferase Val158Met on cortical function in healthy subjects and patients with schizophrenia
    Diana P Prata
    Division of Psychological Medicine and Psychiatry, Institute of Psychiatry, King s College, London, United Kingdom
    Biol Psychiatry 65:473-80. 2009
    ..We addressed this by comparing the effects of COMT Val158Met genotype on cortical activation during a task of executive functions in healthy and schizophrenic subjects...
  12. pmc Higher cortisol levels are associated with smaller left hippocampal volume in first-episode psychosis
    Valeria Mondelli
    Department of Psychological Medicine, Institute of Psychiatry, King s College London, London, UK
    Schizophr Res 119:75-8. 2010
    ..Our findings suggest that smaller hippocampal volume in first-episode psychosis can partly be explained by stress-related processes in the brain, as measured by cortisol hyper-secretion...
  13. ncbi request reprint P50 auditory evoked potential suppression in bipolar disorder patients with psychotic features and their unaffected relatives
    Katja K Schulze
    Section of General Psychiatry, Social, Genetic Developmental Psychiatry Research Centre, Institute of Psychiatry, King s College, London, UK, and Psychology Research Laboratory, McLean Hospital, Belmont, MA, USA
    Biol Psychiatry 62:121-8. 2007
    ..We therefore assessed whether diminished P50 suppression is associated with familial risk for psychotic bipolar disorder...
  14. doi request reprint Increased inferior frontal activation during word generation: a marker of genetic risk for schizophrenia but not bipolar disorder?
    Sergi G Costafreda
    Institute of Psychiatry, King s College London, London, United Kingdom
    Hum Brain Mapp 30:3287-98. 2009
    ..Increased engagement of the inferior frontal cortex during verbal-fluency may thus be a marker of genetic vulnerability to schizophrenia...
  15. doi request reprint Executive functioning in familial bipolar I disorder patients and their unaffected relatives
    Katja K Schulze
    King s Health Partners, Institute of Psychiatry, Department of Psychosis Studies and Department of Psychology, King s College London, NIHR Biomedical Research Centre, London, UK
    Bipolar Disord 13:208-16. 2011
    ..To compare the executive function of patients with familial bipolar I disorder (BP-I) with a history of psychotic symptoms to their first-degree relatives and normal controls...
  16. pmc Pattern of neural responses to verbal fluency shows diagnostic specificity for schizophrenia and bipolar disorder
    Sergi G Costafreda
    Institute of Psychiatry, King s College London, De Crespigny Park, London UK
    BMC Psychiatry 11:18. 2011
    ..Determining the distinct pattern of neural responses in schizophrenia and bipolar disorder may provide biomarkers for their diagnoses...
  17. ncbi request reprint Familial liability to schizophrenia and premorbid adjustment
    Muriel Walshe
    Division of Psychological Medicine, Institute of Psychiatry, De Crespigny Park, London SE5 8AF, UK
    Br J Psychiatry 191:260-1. 2007
    ..Unaffected siblings from multiply affected families also had poor academic functioning in adolescence, with a decline between childhood and adolescence. This may represent a familial (presumed genetic) effect...
  18. doi request reprint Memory functioning in familial bipolar I disorder patients and their relatives
    Seema Quraishi
    NIHR Biomedical Research Centre for Mental Health, South London and Maudsley Foundation NHS Trust and Institute of Psychiatry, King s College London, De Crespigny Park, London, UK
    Bipolar Disord 11:209-14. 2009
    ..The aim of this study was to compare the memory function of patients with familial bipolar I disorder (BD I) who had shown psychotic features, their non-psychotic, non-bipolar first-degree relatives, and normal controls...
  19. ncbi request reprint The relationship between volumetric brain changes and cognitive function: a family study on schizophrenia
    Timothea Toulopoulou
    Division of Psychological Medicine, Section of General Psychiatry, Institute of Psychiatry, London, United Kingdom
    Biol Psychiatry 56:447-53. 2004
    ....
  20. doi request reprint Linear and non-linear associations of symptom dimensions and cognitive function in first-onset psychosis
    Eugenia Kravariti
    NIHR Biomedical Research Centre for Mental Health, South London and Maudsley NHS Foundation Trust and Institute of Psychiatry, King s College London, De Crespigny Park, London SE5 8AF, UK
    Schizophr Res 140:221-31. 2012
    ..It also extended the research focus to mania, a less studied symptom dimension...
  21. doi request reprint Hypothalamic-pituitary-adrenal axis and clinical symptoms in first-episode psychosis
    Martino Belvederi Murri
    Institute of Psychiatry, King s College London, Department of Psychological Medicine, London, UK
    Psychoneuroendocrinology 37:629-44. 2012
    ..The aim of this study was to investigate the association between HPA axis activity and clinical symptoms in first-episode psychosis, taking into account diagnosis and illness phase...
  22. ncbi request reprint Grey and white matter distribution in very preterm adolescents mediates neurodevelopmental outcome
    Chiara Nosarti
    Department of Psychiatry, King s College London Institute of Psychiatry, Denmark Hill, London, UK
    Brain 131:205-17. 2008
    ..Thus, anatomical brain changes may contribute to specific cognitive deficits associated with VPT birth and could be used in the identification of those individuals who may be at increased risk for cognitive impairment...
  23. doi request reprint Childhood trauma and cognitive function in first-episode affective and non-affective psychosis
    Monica Aas
    Department of Psychological Medicine, Institute of Psychiatry, King s College London, UK
    Schizophr Res 129:12-9. 2011
    ..The potential impact of diagnosis (schizophrenia or affective psychosis) and gender on this association was also examined...
  24. doi request reprint Stroop-test interference in bipolar disorder
    Eugenia Kravariti
    Institute of Psychiatry, King s College London, De Crespigny Park, London SE5 8AF, UK
    Br J Psychiatry 194:285-6. 2009
    ..Having a first-degree relative with bipolar disorder, even a familial, psychotic form, did not confer risk for enhanced susceptibility to interference in our studies...
  25. ncbi request reprint Heritability and reliability of P300, P50 and duration mismatch negativity
    Mei Hua Hall
    Social, Genetic Developmental Psychiatry Research Centre, Institute of Psychiatry, King s College London, PO80, De Crespigny Park, London, SE5 8AF, UK
    Behav Genet 36:845-57. 2006
    ..Event-related potentials (ERPs) have been suggested as possible endophenotypes of schizophrenia. We investigated the test-retest reliabilities and heritabilities of three ERP components in healthy monozygotic and dizygotic twin pairs...
  26. ncbi request reprint Genetic overlap between bipolar illness and event-related potentials
    Mei Hua Hall
    Social, Genetic and Developmental Psychiatry Research Centre, Institute of Psychiatry, King s College London, UK
    Psychol Med 37:667-78. 2007
    ....
  27. doi request reprint Is there a link between childhood trauma, cognition, and amygdala and hippocampus volume in first-episode psychosis?
    Monica Aas
    Department of Psychosis Studies, Institute of Psychiatry, King s College London, London, UK
    Schizophr Res 137:73-9. 2012
    ..This points to a complex relationship between childhood trauma exposure, cognitive function and amygdala volume in first-episode psychosis...
  28. pmc Prefrontal deviations in function but not volume are putative endophenotypes for schizophrenia
    Sheena F Owens
    Department of Psychosis Studies, Institute of Psychiatry, Kings College, London, UK
    Brain 135:2231-44. 2012
    ....
  29. doi request reprint Selective deficits in semantic verbal fluency in patients with a first affective episode with psychotic symptoms and a positive history of mania
    Eugenia Kravariti
    Department of Psychiatry, NIHR Biomedical Research Centre, Maudsley NHS Foundation Trust Institute of Psychiatry, King s College London, Box 58, De Crespigny Park, London SE5 8AF, UK
    Bipolar Disord 11:323-9. 2009
    ..We investigated neuropsychological performance in an epidemiologically derived sample of patients with a first affective episode with psychotic symptoms and a positive history of mania, compared to community controls...
  30. pmc Epistasis between the DAT 3' UTR VNTR and the COMT Val158Met SNP on cortical function in healthy subjects and patients with schizophrenia
    Diana P Prata
    Division of Psychological Medicine and Psychiatry, Institute of Psychiatry, King s College London, London WC2R 2LS, United Kingdom
    Proc Natl Acad Sci U S A 106:13600-5. 2009
    ....
  31. doi request reprint Very preterm adolescents show gender-dependent alteration of the structural brain correlates of spelling abilities
    Fiona E Scott
    Department of Psychosis Studies, Institute of Psychiatry, King s Health Partners, King s College London, London, UK
    Neuropsychologia 49:2685-93. 2011
    ....
  32. ncbi request reprint The relationship between eye movement and brain structural abnormalities in patients with schizophrenia and their unaffected relatives
    Katja Schulze
    Division of Psychological Medicine, Institute of Psychiatry, De Crespigny Park, London SE5 8AF, UK
    J Psychiatr Res 40:589-98. 2006
    ..28, p=0.01). There were no significant between-group differences in the relationship between measures of eye movement and morphometry...
  33. doi request reprint Differential relationship between neurological and cognitive dysfunction in first episode psychosis patients and in healthy individuals
    Zefiro Mellacqua
    King s College London, Institute of Psychiatry, Department of Psychosis Studies, London, UK
    Schizophr Res 142:159-64. 2012
    ..004); and motor signs with poorer verbal abilities (p=0.001). These findings indicate the presence of specific associations between neurological and cognitive deficits in psychosis that are distinct from those of healthy individuals...
  34. pmc Volumetric abnormalities predating the onset of schizophrenia and affective psychoses: an MRI study in subjects at ultrahigh risk of psychosis
    Paola Dazzan
    Department of Psychosis Studies, Section of Early Psychosis, Institute of Psychiatry, King s College London, De Crespigny Park, London, UK
    Schizophr Bull 38:1083-91. 2012
    ....
  35. doi request reprint Excellent school performance at age 16 and risk of adult bipolar disorder: national cohort study
    James H MacCabe
    Department of Psychiatry, Institute of Psychiatry, King s College London, London SE5 8AF, UK
    Br J Psychiatry 196:109-15. 2010
    ..Anecdotal and biographical reports suggest that bipolar disorder may be associated with high IQ or creativity, but evidence for any such connection is weak...
  36. ncbi request reprint Sexually dimorphic changes in the amygdala in relation to delusional beliefs in first episode psychosis
    Ayana A Gibbs
    Division of Psychological Medicine, Institute of Psychiatry, King s College, P O Box, De Crespigny Park, London SE5 8AF, UK
    J Psychiatr Res 42:913-9. 2008
    ..The present study explored the relationship between amygdala morphology and mood congruent and mood incongruent delusional beliefs...
  37. ncbi request reprint Magnetic resonance imaging of the thalamus and adhesio interthalamica in twins with schizophrenia
    Ulrich Ettinger
    Centre for Neuroimaging Sciences, Division of Psychological Medicine, Institute of Psychiatry, King s College London, London, England
    Arch Gen Psychiatry 64:401-9. 2007
    ..However, it is not clear to what extent these abnormalities are determined by the genetic liability for schizophrenia...
  38. ncbi request reprint Duration of prodromal phase and severity of volumetric abnormalities in first-episode psychosis
    Julia M Lappin
    King s College London, Institute of Psychiatry, London, UK
    Br J Psychiatry Suppl 51:s123-7. 2007
    ..First-episode psychosis is typically preceded by a prodrome in which there is deterioration in global and social functioning...
  39. doi request reprint Neural substrates of letter fluency processing in young adults who were born very preterm: alterations in frontal and striatal regions
    Chiara Nosarti
    Department of Psychiatry, Biomedical Research Centre for Mental Health, Institute of Psychiatry and King s College London, London, UK
    Neuroimage 47:1904-13. 2009
    ..However, fMRI results were only partly explained by structural changes, and may reflect processes of functional plasticity for the successful completion of executive-type operations...
  40. ncbi request reprint Intellectual asymmetry and genetic liability in first-degree relatives of probands with schizophrenia
    Eugenia Kravariti
    Institute of Psychiatry, Department of Psychiatry, Division of Psychological Medicine, Box 63, De Crespigny Park, London SE5 8AF, UK
    Br J Psychiatry 188:186-7. 2006
    ..Intellectual asymmetry with a relative superiority of verbal skills to spatial skills represents a putative endophenotype of schizophrenia...
  41. ncbi request reprint Antisaccade performance in monozygotic twins discordant for schizophrenia: the Maudsley twin study
    Ulrich Ettinger
    Centre for Neuroimaging Sciences, Institute of Psychiatry, King s College London, London SE5 8AF, UK
    Am J Psychiatry 163:543-5. 2006
    ..Deficiency in antisaccade performance has been proposed as a schizophrenia endophenotype...
  42. doi request reprint Evidence of association of KIBRA genotype with episodic memory in families of psychotic patients and controls
    Evangelos Vassos
    King s College London, Institute of Psychiatry, Department of Psychological Medicine and Psychiatry and NIHR Biomedical Research Centre, London, UK
    J Psychiatr Res 44:795-8. 2010
    ..05). This study replicates the association between the KIBRA gene and episodic memory and suggests a possibly differential effect of the polymorphism in psychotic and non-psychotic individuals...
  43. doi request reprint Auditory P300 in patients with bipolar disorder and their unaffected relatives
    Katja K Schulze
    Division of Psychological Medicine, Institute of Psychiatry, King s College, London, UK
    Bipolar Disord 10:377-86. 2008
    ....
  44. ncbi request reprint Association between BDNF val66 met genotype and episodic memory
    Emma Dempster
    Section of Molecular Genetics, Division of Psychological Medicine, Institute of Psychiatry, London, United Kingdom
    Am J Med Genet B Neuropsychiatr Genet 134:73-5. 2005
    ..When cases and unaffected relatives were analyzed separately, met66 was associated with a lower score on the WMS delayed measure in the relatives only (R2 = 0.077 P = 0.01), which is consistent with previous findings...
  45. pmc Association between the 2-bp deletion polymorphism in the duplicated version of the alpha7 nicotinic receptor gene and P50 sensory gating
    Rachel H Flomen
    Department of Clinical Neuroscience, Institute of Psychiatry, King s College London, London, UK
    Eur J Hum Genet 21:76-81. 2013
    ..Four out of six previous association studies found association of different psychiatric phenotypes with the same 2-bp deletion allele...
  46. doi request reprint Superior intellectual ability in schizophrenia: neuropsychological characteristics
    James H MacCabe
    Department of Psychosis Studies, Institute of Psychiatry, King s College London, De Crespigny Park, London, SE5 8AF, United Kingdom
    Neuropsychology 26:181-90. 2012
    ..In this study, we sought out schizophrenia patients with an estimated premorbid Intelligence Quotient (IQ) of at least 115 and studied their neuropsychological profile...
  47. doi request reprint Reduced mismatch negativity predates the onset of psychosis
    Madiha Shaikh
    PO63, NIHR Biomedical Research Centre for Mental Health at the Institute of Psychiatry, King s College London and The South London and Maudsley NHS Foundation Trust, London, SE5 8AF, UK
    Schizophr Res 134:42-8. 2012
    ..We examined whether mismatch negativity (MMN) could help to identify those who are particularly likely to make a transition to psychosis...
  48. ncbi request reprint The nature of abnormal language processing in euthymic bipolar I disorder: evidence for a relationship between task demand and prefrontal function
    Vivienne A Curtis
    Division of Psychological Medicine, Institute of Psychiatry, London, UK
    Bipolar Disord 9:358-69. 2007
    ..We used functional magnetic resonance imaging (fMRI) to investigate the core components of language processing as well as the impact of task demand in a group of bipolar subjects...
  49. ncbi request reprint Association analysis of dopamine D2-like receptor genes and methamphetamine abuse
    Chih Ken Chen
    Division of Psychological Medicine, Institute of Psychiatry, University of London, UK
    Psychiatr Genet 14:223-6. 2004
    ..This study employs an association approach to examine the genetic underpinning of methamphetamine (MAMP) use and MAMP-induced psychosis...
  50. doi request reprint Differential effects of DAAO on regional activation and functional connectivity in schizophrenia, bipolar disorder and controls
    Sergio Alessandro Papagni
    Department of Psychosis Studies, Institute of Psychiatry, King s College London, De Crespigny Park, SE5 8AF, UK
    Neuroimage 56:2283-91. 2011
    ..Our results suggest that genetic variation in DAAO has a significant impact on both regional activation and functional connectivity, and provide evidence for a diagnosis-dependent pattern of gene action...
  51. pmc Migration, ethnicity, and psychosis: toward a sociodevelopmental model
    Craig Morgan
    Section of Society, Culture and Mental Health, Health Service and Population Research Department, Box 33, Institute of Psychiatry, De Crespigny Park, London SE5 8AF, UK
    Schizophr Bull 36:655-64. 2010
    ....
  52. ncbi request reprint A diffusion tensor imaging study of fasciculi in schizophrenia
    Sukhwinder S Shergill
    Institute of Psychiatry, Kings College London, De Crespigny Park, UK
    Am J Psychiatry 164:467-73. 2007
    ..This study used diffusion tensor imaging to examine the integrity of the major white matter fasciculi, which connects the frontal and temporal-parietal cortices, and the corpus callosum in patients with schizophrenia...
  53. pmc The relationship between prolactin levels and glucose homeostasis in antipsychotic-treated schizophrenic patients
    Oliver D Howes
    Division of Psychological Medicine, Institute of Psychiatry, De Crespigny Park, Denmark Hill, London, UK
    J Clin Psychopharmacol 26:629-31. 2006
    ..To determine if prolactin levels are associated with glucose-insulin homeostasis in antipsychotic-treated patients with schizophrenia...
  54. ncbi request reprint Different effects of typical and atypical antipsychotics on grey matter in first episode psychosis: the AESOP study
    Paola Dazzan
    Division of Psychological Medicine, Institute of Psychiatry, King s College, London, UK
    Neuropsychopharmacology 30:765-74. 2005
    ..In conclusion, we would like to suggest that even after short-term treatment, typical and atypical antipsychotics may affect brain structure differently...
  55. doi request reprint Neurocognitive performance in children aged 9-12 years who present putative antecedents of schizophrenia
    Alexis E Cullen
    King s College London, Department of Forensic and Neurodevelopmental Sciences Box P023, Institute of Psychiatry, De Crespigny Park, London SE5 8AF, United Kingdom
    Schizophr Res 121:15-23. 2010
    ..The present study aimed to determine whether ASz children also present neurocognitive deficits that are commonly observed in patients with schizophrenia...
  56. doi request reprint Association between hippocampal volume and P300 event related potential in psychosis: support for the Kraepelinian divide
    Anirban Dutt
    NIHR Biomedical Research Centre, Institute of Psychiatry King s College London South London and Maudsley NHS Foundation Trust, London, UK
    Neuroimage 59:997-1003. 2012
    ....
  57. pmc White matter and cognition in adults who were born preterm
    Matthew P G Allin
    King s Health Partners, King s College London, Department of Psychosis Studies, Institute of Psychiatry, London, United Kingdom
    PLoS ONE 6:e24525. 2011
    ..Individuals born very preterm (before 33 weeks of gestation, VPT) are at risk of damage to developing white matter, which may affect later cognition and behaviour...
  58. doi request reprint Self-harm in first-episode psychosis
    Samuel B Harvey
    Department of Psychological Medicine, Institute of Psychiatry, King s College London, Weston Education Centre, 10 Cutcombe Road, London SE5 9RJ, UK
    Br J Psychiatry 192:178-84. 2008
    ..Little is known about self-harm occurring during the period of untreated first-episode psychosis...
  59. ncbi request reprint Cognitive performance in presumed obligate carriers for psychosis
    Timothea Toulopoulou
    Division of Psychological Medicine, Institute of Psychiatry, London, UK
    Br J Psychiatry 187:284-5. 2005
    ....
  60. ncbi request reprint Hippocampal volume in familial and nonfamilial schizophrenic probands and their unaffected relatives
    Katja Schulze
    Division of Psychological Medicine, Institute of Psychiatry, London, United Kingdom
    Biol Psychiatry 53:562-70. 2003
    ..The aim of our study was to assess the contribution of familial liability and obstetric complications to hippocampal volume reduction in schizophrenia...
  61. doi request reprint Selective attention deficits reflect increased genetic vulnerability to schizophrenia
    Francesca M Filbey
    Department of Psychiatry, Institute of Psychiatry, King s College, De Crespigny Park, SE5 8AF London, UK
    Schizophr Res 101:169-75. 2008
    ..Impairment in attention is prominent in schizophrenia and may be a valuable genetic indicator for vulnerability to this disease...
  62. doi request reprint Error-related processing dysfunction in children aged 9 to 12 years presenting putative antecedents of schizophrenia
    Kristin R Laurens
    Department of Forensic Mental Health Science, Institute of Psychiatry, King s College London, London SE5 8AF, United Kingdom
    Biol Psychiatry 67:238-45. 2010
    ..This study examined whether ASz children display brain function abnormalities during error processing that are similar to those exhibited by adults with schizophrenia...
  63. doi request reprint Pituitary volume in unaffected relatives of patients with schizophrenia and bipolar disorder
    Valeria Mondelli
    Division of Psychological Medicine, Institute of Psychiatry, King s College London, London, UK
    Psychoneuroendocrinology 33:1004-12. 2008
    ..The aim of this study was to assess the contribution of familial liability to pituitary volume in schizophrenia and bipolar disorder. Pituitary volume may be an indirect measure of HPA axis activity...
  64. doi request reprint Correlation and familial aggregation of dimensions of psychosis in affected sibling pairs from China
    Evangelos Vassos
    King s College London, Institute of Psychiatry, Division of Psychological Medicine and Psychiatry, London, UK
    Br J Psychiatry 193:305-10. 2008
    ..A number of studies with conflicting results have examined the familiality of schizophrenia syndromes in Western populations...
  65. doi request reprint Structural covariance in the cortex of very preterm adolescents: a voxel-based morphometry study
    Chiara Nosarti
    Department of Psychosis Studies, Biomedical Research Centre for Mental Health, Institute of Psychiatry and King s College London, London, UK
    Hum Brain Mapp 32:1615-25. 2011
    ....
  66. pmc High-potency cannabis and the risk of psychosis
    Marta Di Forti
    Department of Psychiatry, Institute of Psychiatry, De Crespigny Park, London SE5 8AF, UK
    Br J Psychiatry 195:488-91. 2009
    ..There has recently been concern over an increase in the concentration of Delta 9-THC in the cannabis available in many countries...
  67. ncbi request reprint The structural brain correlates of neurological soft signs in healthy individuals
    Paola Dazzan
    King s College London, Institute of Psychiatry, Division of Psychological Medicine, London, UK
    Cereb Cortex 16:1225-31. 2006
    ..Therefore, we suggest that these cortical brain structural changes represent a common neuroanatomical substrate of NSS, across healthy individuals and patients with psychosis...
  68. pmc Reliability and comparability of psychosis patients' retrospective reports of childhood abuse
    Helen L Fisher
    Institute of Psychiatry, King s College London, De Crespigny Park, London SE5 8AF, UK
    Schizophr Bull 37:546-53. 2011
    ..159, P=.419; antipathy: χ(2)=0.868, P=.229; neglect: χ(2)=0.639, P=.274). These findings provide justification for the use in future studies of retrospective reports of childhood abuse obtained from individuals with psychotic disorders...
  69. pmc Sexual function and gonadal hormones in patients taking antipsychotic treatment for schizophrenia or schizoaffective disorder
    Oliver D Howes
    Institute of Psychiatry, De Crespigny Park, London, UK
    J Clin Psychiatry 68:361-7. 2007
    ..To determine rates of sexual dysfunction and hypogonadism and establish the relationship between gonadal hormone levels and sexual function in patients taking antipsychotic treatment for schizophrenia or schizoaffective disorder...
  70. doi request reprint Genetic liability for bipolar disorder is characterized by excess frontal activation in response to a working memory task
    Dominique Drapier
    Section of Neuroscience and Emotion, Psychological Medicine and Psychiatry, King s College London Institute of Psychiatry, London, United Kingdom
    Biol Psychiatry 64:513-20. 2008
    ..We utilized functional magnetic resonance imaging (fMRI) to investigate neural activity in samples of bipolar disorder patients and their unaffected first-degree relatives while performing working memory tasks of increasing difficulty...
  71. ncbi request reprint Eye tracking in schizophrenia: does the antisaccade task measure anything that the smooth pursuit task does not?
    Jolanta Zanelli
    Division of Psychological Medicine, Institute of Psychiatry, King s College London, De Crespigny Park, London SE5 8AF, UK
    Psychiatry Res 136:181-8. 2005
    ..The finding may reflect a shared genetic liability, that affects both eye-tracking phenotypes. It is likely that both measures reflect frontal cortical dysfunction...
  72. doi request reprint The neural basis of response inhibition and attention allocation as mediated by gestational age
    Emma J Lawrence
    Department of Psychological Medicine, Institute of Psychiatry, King s College London, United Kingdom
    Hum Brain Mapp 30:1038-50. 2009
    ....
  73. ncbi request reprint Hyperactivity in adolescents born very preterm is associated with decreased caudate volume
    Chiara Nosarti
    Division of Psychological Medicine, Institute of Psychiatry, London, United Kingdom
    Biol Psychiatry 57:661-6. 2005
    ....
  74. ncbi request reprint Association of genetic risks for schizophrenia and bipolar disorder with specific and generic brain structural endophenotypes
    Colm McDonald
    Division of Psychological Medicine, Institute of Psychiatry, London
    Arch Gen Psychiatry 61:974-84. 2004
    ..For more than a century, it has been uncertain whether or not the major diagnostic categories of psychosis--schizophrenia and bipolar disorder--are distinct disease entities with specific genetic causes and neuroanatomical substrates...
  75. pmc The epidemiology of schizophrenia: replacing dogma with knowledge
    Simona A Stilo
    Psychosis Clinical Academic Group, Institute of Psychiatry, King s Health Partners, King s College London, UK
    Dialogues Clin Neurosci 12:305-15. 2010
    ....
  76. pmc A dopamine transporter gene functional variant associated with cocaine abuse in a Brazilian sample
    Camila Guindalini
    Medical Research Council Social Genetic and Developmental Psychiatry Research Centre, Division of Psychological Medicine, Institute of Psychiatry, King s College London, London SE5 8AF, United Kingdom
    Proc Natl Acad Sci U S A 103:4552-7. 2006
    ..This study suggests that DAT1 gene variation may play a role in cocaine dependence etiology...
  77. ncbi request reprint Genetic overlap between P300, P50, and duration mismatch negativity
    Mei Hua Hall
    Social, Genetic Developmental Psychiatry Research Centre, Institute of Psychiatry, King s College London, London, United Kingdom
    Am J Med Genet B Neuropsychiatr Genet 141:336-43. 2006
    ..Within paradigm, P300 amplitude and latency shared about half of their genetic effects...
  78. ncbi request reprint Cannabis use and psychiatric and cogitive disorders: the chicken or the egg?
    Marta Di Forti
    Department of Psychological Medicine, Institute of Psychiatry, London, UK
    Curr Opin Psychiatry 20:228-34. 2007
    ..Cannabis is the world's most commonly used illicit drug. In this review, we consider the recent literature on the effects of cannabis on mental health and on cognition...
  79. doi request reprint Cerebellar growth and behavioural & neuropsychological outcome in preterm adolescents
    Jennifer Parker
    King s College London, Division of Psychological Medicine and Psychiatry, Institute of Psychiatry, London, UK
    Brain 131:1344-51. 2008
    ..We have demonstrated a reduction in cerebellar volume between adolescence and young adulthood in VPT individuals, which is correlated with reduced self-reported wellbeing...
  80. ncbi request reprint Schizophrenia and bipolar disorder: similarities in pathogenic mechanisms but differences in neurodevelopment
    Jenny Walker
    Institute of Psychiatry, Denmark Hill, London, UK
    Int Clin Psychopharmacol 17:S11-9. 2002
    ..In particular, genes involved in early cortical development and early neurodevelopmental insults causing developmental impairment may put individuals on a trajectory towards schizophrenia rather than bipolar illness...
  81. ncbi request reprint Saccadic distractibility is elevated in schizophrenia patients, but not in their unaffected relatives
    James H MacCabe
    Division of Psychological Medicine, Institute of Psychiatry, London, UK
    Psychol Med 35:1727-36. 2005
    ..Some studies have suggested that this measure is elevated in the unaffected relatives of schizophrenia patients. However, recent studies have called this into question and the topic remains controversial...
  82. doi request reprint Substance use in adolescence and psychosis: clarifying the relationship
    Emma Barkus
    Institute of Psychiatry, King s College London, De Crespigny Park, SE58A4 London, United Kingdom
    Annu Rev Clin Psychol 6:365-89. 2010
    ..Here we review the association of alcohol, cannabis, stimulants, and other drugs with psychosis, and we conclude that the use of cannabis and the amphetamines significantly contributes to the risk of psychosis...
  83. doi request reprint What is the mechanism whereby cannabis use increases risk of psychosis?
    Sonija Luzi
    Institute of Psychiatry, Division of Psychological Medicine, Denmark Hill, London, SE5 8AF, UK
    Neurotox Res 14:105-12. 2008
    ..This paper starts to consider the neurochemical mechanisms whereby cannabis use increases the risk of psychosis...
  84. doi request reprint Abnormal P300 in people with high risk of developing psychosis
    Elvira Bramon
    Institute of Psychiatry, Division of Psychological Medicine Box 63, De Crespigny Park, London, SE5 8AF, UK
    Neuroimage 41:553-60. 2008
    ..We examined whether neurophysiological markers could help to identify those who are particularly vulnerable...
  85. doi request reprint Neuropsychological functioning in first-episode schizophrenia
    Eugenia Kravariti
    Department of Psychiatry, NIHR Biomedical Research Centre for Mental Health, South London and Maudsley NHS Foundation Trust and Institute of Psychiatry, King s College London, London
    Br J Psychiatry 195:336-45. 2009
    ....
  86. ncbi request reprint Regional volume deviations of brain structure in schizophrenia and psychotic bipolar disorder: computational morphometry study
    Colm McDonald
    Division of Psychological Medicine, Box 63, Institute of Psychiatry, De Crespigny Park, London SE5 8AF, UK
    Br J Psychiatry 186:369-77. 2005
    ..It is unclear whether schizophrenia and psychotic bipolar disorder are associated with similar deviations of brain morphometry...
  87. pmc Bone mineral density and its relationship to prolactin levels in patients taking antipsychotic treatment
    Oliver D Howes
    The Institute of Psychiatry, London SE5 8AF, UK
    J Clin Psychopharmacol 25:259-61. 2005
    ..BMD was correlated with body mass index but there was no correlation with prolactin. BMD was not correlated with prolactin levels and showed no clinically significant reduction. The low BMD in black males warrants further investigation...
  88. ncbi request reprint Vermis and lateral lobes of the cerebellum in adolescents born very preterm
    Matthew P G Allin
    Institute of Psychiatry, King s College, University College London Medical School, London, UK
    Neuroreport 16:1821-4. 2005
    ..Vermis volume was less strongly related to cognitive function. Volume decrement of the lateral lobes, rather than the vermis, is associated with neuropsychological dysfunction in very preterm individuals...
  89. ncbi request reprint Gender differences in incidence and age at onset of mania and bipolar disorder over a 35-year period in Camberwell, England
    Noel Kennedy
    Section of General Psychiatry, Division of Psychological Medicine, Institute of Psychiatry, De Crespigny Park, London SE5 8AF, UK
    Am J Psychiatry 162:257-62. 2005
    ..The authors investigated gender differences in age at onset and incidence of first-episode mania and bipolar disorder in an epidemiological catchment area in southeast London over a 35-year period...
  90. ncbi request reprint Obstetric complications and schizophrenia: historical and meta-analytic review
    Mary Cannon
    Division of Psychological Medicine P063, Institute of Psychiatry, De Crespigny Park, London SE5 8AF, UK
    Am J Psychiatry 159:1080-92. 2002
    ..The authors trace the evolution of this literature through different methods and carry out a quantitative review of the results from prospective, population-based studies...
  91. pmc Environmental risk factors for psychosis
    Kimberlie Dean
    Division of Psychological Medicine, Institute of Psychiatry, London, UK
    Dialogues Clin Neurosci 7:69-80. 2005
    ..As the etiology of schizophrenia is unraveled, the picture becomes more complex, but also more obviously relevant to the plight of the individual patient...
  92. doi request reprint Reassessing the long-term risk of suicide after a first episode of psychosis
    Rina Dutta
    Department of Psychosis Studies, Institute of Psychiatry, King s College London, England
    Arch Gen Psychiatry 67:1230-7. 2010
    ....
  93. doi request reprint Impaired intellect and memory: a missing link between genetic risk and schizophrenia?
    Timothea Toulopoulou
    King s College London, United Kingdom
    Arch Gen Psychiatry 67:905-13. 2010
    ..Although a variety of candidate intermediate phenotypes have emerged, few have explicitly quantified the extent of their genetic overlap with schizophrenia...
  94. ncbi request reprint Increased pituitary volume in antipsychotic-free and antipsychotic-treated patients of the AEsop first-onset psychosis study
    Carmine M Pariante
    Stress, Psychiatry and Immunology Laboratory, Division of Psychological Medicine, Clinical Neuropharmacology PO51, Institute of Psychiatry, King s College London, 1 Windsor Walk, Denmark Hill, London SE5 8AF, UK
    Neuropsychopharmacology 30:1923-31. 2005
    ..This activation of the hormonal stress response could participate to the important metabolic abnormalities observed in patients with psychosis...
  95. ncbi request reprint Modulation of activity in temporal cortex during generation of inner speech
    Sukhwinder S Shergill
    Institute of Psychiatry, GKT School of Medicine and Dentistry, De Crespigny Park, London, United Kingdom
    Hum Brain Mapp 16:219-27. 2002
    ..Furthermore, this may provide support for the existence of feed forward models, which suggest that activity in regions responsible for verbal perception is modulated by activity in areas that generate inner speech...
  96. pmc Biological, life course, and cross-cultural studies all point toward the value of dimensional and developmental ratings in the classification of psychosis
    Rina Dutta
    Division of Psychological Medicine and Psychiatry, Institute of Psychiatry, King s College London, UK
    Schizophr Bull 33:868-76. 2007
    ..However, we will begin by briefly reviewing the recent history of the classification of the psychoses...
  97. ncbi request reprint Prevalence of violent victimisation in severe mental illness
    Elizabeth Walsh
    Institute of Psychiatry, Section of Forensic Mental Health, Denmark Hill, London, UK
    Br J Psychiatry 183:233-8. 2003
    ..Since de-institutionalisation, much has been written about the risk posed to the community by those with severe mental illness. However, violent victimisation of people with mental illnesses has received little attention...
  98. pmc Schizophrenia
    Marco M Picchioni
    King s College London, Institute of Psychiatry, Division of Psychological Medicine, London SE5 8AF
    BMJ 335:91-5. 2007
  99. ncbi request reprint The structural brain correlates of neurological soft signs in AESOP first-episode psychoses study
    Paola Dazzan
    Division of Psychological Medicine, Box 63, Institute of Psychiatry, De Crespigny Park, London SE5 8AF, UK
    Brain 127:143-53. 2004
    ....
  100. ncbi request reprint Causal association between cannabis and psychosis: examination of the evidence
    Louise Arseneault
    MRC Social, Genetic, and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, UK
    Br J Psychiatry 184:110-7. 2004
    ..Controversy remains as to whether cannabis acts as a causal risk factor for schizophrenia or other functional psychotic illnesses...
  101. ncbi request reprint Evidence for association between novel polymorphisms in the PRODH gene and schizophrenia in a Chinese population
    Tao Li
    Division of Psychological Medicine, Institute of Psychiatry, London, United Kingdom
    Am J Med Genet B Neuropsychiatr Genet 129:13-5. 2004
    ..Overall this finding supports a role for the PRODH locus in schizophrenia...