Declan G M Murphy

Summary

Affiliation: King's College London
Country: UK

Publications

  1. pmc Fragile X syndrome: a pilot proton magnetic resonance spectroscopy study in premutation carriers
    Brian P Hallahan
    Department of Psychiatry, National University of Ireland Galway, Galway, Ireland
    J Neurodev Disord 4:23. 2012
  2. pmc Rates of undiagnosed attention deficit hyperactivity disorder in London drug and alcohol detoxification units
    Zoe Huntley
    MRC Social Genetic and Developmental Psychiatry, Institute of Psychiatry, Kings College London, London, SE 58AF, UK
    BMC Psychiatry 12:223. 2012
  3. doi request reprint Autism in adults. New biologicial findings and their translational implications to the cost of clinical services
    Declan G M Murphy
    Department of Forensic and Developmental Sciences, Institute of Psychiatry, Kings College London, London, UK
    Brain Res 1380:22-33. 2011
  4. ncbi request reprint Serotonin and the neural processing of facial emotions in adults with autism: an fMRI study using acute tryptophan depletion
    Eileen M Daly
    Department of Forensic and Neurodevelopmental Science, Institute of Psychiatry, King s College London, London, England
    Arch Gen Psychiatry 69:1003-13. 2012
  5. doi request reprint Hippocampal proton MR spectroscopy in early Alzheimer's disease and mild cognitive impairment
    Catherine M L Foy
    Institute of Psychiatry, MRC Centre for Neurodegeneration Research, King s College London, London, UK
    Brain Topogr 24:316-22. 2011
  6. doi request reprint White matter microstructural abnormalities in the frontal lobe of adults with antisocial personality disorder
    Frederick Sundram
    King s College London, Institute of Psychiatry, Department of Forensic and Neurodevelopmental Science, London, UK Department of Psychiatry, Royal College of Surgeons in Ireland, Dublin, Ireland
    Cortex 48:216-29. 2012
  7. doi request reprint The anatomy of extended limbic pathways in Asperger syndrome: a preliminary diffusion tensor imaging tractography study
    Luca Pugliese
    Section of Brain Maturation, Institute of Psychiatry, King s College London, London SE5 8AF, UK
    Neuroimage 47:427-34. 2009
  8. ncbi request reprint An event related functional magnetic resonance imaging study of facial emotion processing in Asperger syndrome
    Quinton Deeley
    Section of Brain Maturation, De Crespigny Park, London, UK
    Biol Psychiatry 62:207-17. 2007
  9. doi request reprint Down syndrome with and without dementia: an in vivo proton Magnetic Resonance Spectroscopy study with implications for Alzheimer's disease
    Melissa Lamar
    Department of Psychological Medicine, Section of Brain Maturation, Institute of Psychiatry, King s College London, London, England, UK
    Neuroimage 57:63-8. 2011
  10. doi request reprint A lateralized brain network for visuospatial attention
    Michel Thiebaut de Schotten
    Natbrainlab, Department of Forensic and Neurodevelopmental Sciences, Institute of Psychiatry, King s College London, London, UK
    Nat Neurosci 14:1245-6. 2011

Detail Information

Publications63

  1. pmc Fragile X syndrome: a pilot proton magnetic resonance spectroscopy study in premutation carriers
    Brian P Hallahan
    Department of Psychiatry, National University of Ireland Galway, Galway, Ireland
    J Neurodev Disord 4:23. 2012
    ..abstract:..
  2. pmc Rates of undiagnosed attention deficit hyperactivity disorder in London drug and alcohol detoxification units
    Zoe Huntley
    MRC Social Genetic and Developmental Psychiatry, Institute of Psychiatry, Kings College London, London, SE 58AF, UK
    BMC Psychiatry 12:223. 2012
    ..One of the most prevalent and impairing comorbidities of ADHD in adults are substance use disorders. We estimate rates of ADHD in patients with substance abuse disorders and delineate impairment in the co-morbid group...
  3. doi request reprint Autism in adults. New biologicial findings and their translational implications to the cost of clinical services
    Declan G M Murphy
    Department of Forensic and Developmental Sciences, Institute of Psychiatry, Kings College London, London, UK
    Brain Res 1380:22-33. 2011
    ....
  4. ncbi request reprint Serotonin and the neural processing of facial emotions in adults with autism: an fMRI study using acute tryptophan depletion
    Eileen M Daly
    Department of Forensic and Neurodevelopmental Science, Institute of Psychiatry, King s College London, London, England
    Arch Gen Psychiatry 69:1003-13. 2012
    ....
  5. doi request reprint Hippocampal proton MR spectroscopy in early Alzheimer's disease and mild cognitive impairment
    Catherine M L Foy
    Institute of Psychiatry, MRC Centre for Neurodegeneration Research, King s College London, London, UK
    Brain Topogr 24:316-22. 2011
    ..Reductions in [NAA] can be detected in the hippocampi of subjects with MCI and hippocampal [NAA] and [Cr + PCr] can distinguish between mild AD and normal elderly controls...
  6. doi request reprint White matter microstructural abnormalities in the frontal lobe of adults with antisocial personality disorder
    Frederick Sundram
    King s College London, Institute of Psychiatry, Department of Forensic and Neurodevelopmental Science, London, UK Department of Psychiatry, Royal College of Surgeons in Ireland, Dublin, Ireland
    Cortex 48:216-29. 2012
    ..Also in the right frontal lobe, increased MD was found in the IFOF and UF, and the corpus callosum and anterior corona radiata. There was a significant positive correlation between MD and psychopathy scores...
  7. doi request reprint The anatomy of extended limbic pathways in Asperger syndrome: a preliminary diffusion tensor imaging tractography study
    Luca Pugliese
    Section of Brain Maturation, Institute of Psychiatry, King s College London, London SE5 8AF, UK
    Neuroimage 47:427-34. 2009
    ..05) (p=.02). Our preliminary findings suggest that people with Asperger syndrome have significant differences in the anatomy, and maturation, of some (but not all) limbic tracts...
  8. ncbi request reprint An event related functional magnetic resonance imaging study of facial emotion processing in Asperger syndrome
    Quinton Deeley
    Section of Brain Maturation, De Crespigny Park, London, UK
    Biol Psychiatry 62:207-17. 2007
    ..However nobody has examined brain function in people with AS when implicitly (unconsciously) processing four primary emotions at varying emotional intensities...
  9. doi request reprint Down syndrome with and without dementia: an in vivo proton Magnetic Resonance Spectroscopy study with implications for Alzheimer's disease
    Melissa Lamar
    Department of Psychological Medicine, Section of Brain Maturation, Institute of Psychiatry, King s College London, London, England, UK
    Neuroimage 57:63-8. 2011
    ..mI] may modify risk for dementia in this vulnerable population...
  10. doi request reprint A lateralized brain network for visuospatial attention
    Michel Thiebaut de Schotten
    Natbrainlab, Department of Forensic and Neurodevelopmental Sciences, Institute of Psychiatry, King s College London, London, UK
    Nat Neurosci 14:1245-6. 2011
    ..Our results suggest that hemispheric specialization is associated with an unbalanced speed of visuospatial processing...
  11. doi request reprint Early specialization for voice and emotion processing in the infant brain
    Anna Blasi
    Department of Forensic and Neurodevelopmental Science, Institute of Psychiatry, King s College London, London SE5 8AF, UK
    Curr Biol 21:1220-4. 2011
    ..These results suggest remarkably early functional specialization for processing human voice and negative emotions...
  12. ncbi request reprint Brain anatomy and sensorimotor gating in Asperger's syndrome
    Grainne M McAlonan
    Department of Psychological Medicine, Institute of Psychiatry, London, UK
    Brain 125:1594-606. 2002
    ....
  13. doi request reprint Brain surface anatomy in adults with autism: the relationship between surface area, cortical thickness, and autistic symptoms
    Christine Ecker
    Department of Forensic and Neurodevelopmental Sciences, Institute of Psychiatry, King s College London, London, UK
    JAMA Psychiatry 70:59-70. 2013
    ..However, CV is a product of 2 distinct parameters, cortical thickness (CT) and surface area (SA), that in turn have distinct genetic and developmental origins...
  14. doi request reprint Fronto-striatal circuitry and inhibitory control in autism: findings from diffusion tensor imaging tractography
    Marieke Langen
    Department of Forensic and Neurodevelopmental Sciences, Institute of Psychiatry, King s College London, UK
    Cortex 48:183-93. 2012
    ..There are few studies, however, that have measured the micro-structural organisation of white matter tracts connecting striatum and frontal cortex...
  15. doi request reprint White matter integrity in Asperger syndrome: a preliminary diffusion tensor magnetic resonance imaging study in adults
    Oswald J N Bloemen
    Section of Brain Maturation, Division of Psychological Medicine, Institute of Psychiatry, King s College London, London, UK
    Autism Res 3:203-13. 2010
    ..However, nobody has investigated the microstructural integrity of whole brain white matter in people with Asperger syndrome...
  16. pmc White matter microstructure in 22q11 deletion syndrome: a pilot diffusion tensor imaging and voxel-based morphometry study of children and adolescents
    Frederick Sundram
    Section of Brain Maturation, Division of Psychological Medicine, Institute of Psychiatry, King s College London, PO Box 50, De Crespigny Park, London, SE5 8AF, UK
    J Neurodev Disord 2:77-92. 2010
    ..Also, there is preliminary evidence that within 22q11DS, some regional differences in FA are associated with allelic variation in COMT and may perhaps also be associated with schizotypy...
  17. ncbi request reprint In vivo 1H-magnetic resonance spectroscopy study of amygdala-hippocampal and parietal regions in autism
    Lisa A Page
    Section of Brain Maturation, Institute of Psychiatry, London
    Am J Psychiatry 163:2189-92. 2006
    ..However, the concentration of glutamate/glutamine in brain regions implicated in autistic spectrum disorders has not yet been examined in vivo...
  18. ncbi request reprint The effect of pre-mutation of X chromosome CGG trinucleotide repeats on brain anatomy
    Caroline J Moore
    Division of Psychological Medicine, Department of Neurology, Institute of Psychiatry, King s College London, DeCrespigny Park, UK
    Brain 127:2672-81. 2004
    ..Moreover, our findings suggest, for the first time, an association between voxel density reduction and genetic variation in FraX...
  19. ncbi request reprint Neural correlates of executive function in autistic spectrum disorders
    Nicole Schmitz
    Department of Psychological Medicine, Section of Brain Maturation, Institute of Psychiatry, King College London, UK
    Biol Psychiatry 59:7-16. 2006
    ..However, to date, no functional imaging study on ASD has investigated inhibition and cognitive flexibility and no one has related EF brain activation to brain structure...
  20. doi request reprint Maturation of limbic regions in Asperger syndrome: a preliminary study using proton magnetic resonance spectroscopy and structural magnetic resonance imaging
    Finian M O'Brien
    Department of Psychological Medicine, Kings College London, UK
    Psychiatry Res 184:77-85. 2010
    ..We therefore suggest that people with AS have significant differences in neuronal and lipid membrane integrity and maturation of the AHC...
  21. ncbi request reprint Brain anatomy in adults with velocardiofacial syndrome with and without schizophrenia: preliminary results of a structural magnetic resonance imaging study
    Therese Van Amelsvoort
    Department of Psychological Medicine, Institute of Psychiatry, London, England
    Arch Gen Psychiatry 61:1085-96. 2004
    ..The biological basis for this increased risk for schizophrenia is unknown, but people with velocardiofacial syndrome may have genetically determined differences in brain anatomy that predispose to the development of schizophrenia...
  22. doi request reprint Executive functions and memory abilities in children with 22q11.2 deletion syndrome
    Linda E Campbell
    Institute of Psychiatry, King s College London, UK
    Aust N Z J Psychiatry 44:364-71. 2010
    ....
  23. doi request reprint Acute tryptophan depletion promotes an anterior-to-posterior fMRI activation shift during task switching in older adults
    Melissa Lamar
    Department of Psychology, Institute of Psychiatry, King s College London, Guy s Campus, London United Kingdom Section of Brain Maturation, Department of Forensic and Neurodevelopmental Science, Institute of Psychiatry, King s College London, De Crespigny Park, London, United Kingdom Department of Psychiatry, University of Illinois at Chicago, Chicago, Illinois
    Hum Brain Mapp 35:712-22. 2014
    ..g., in vascular or late life depression). Hum Brain Mapp 35:712-722, 2014. © 2012 Wiley Periodicals, Inc. ..
  24. pmc Is theory of mind related to social dysfunction and emotional problems in 22q11.2 deletion syndrome (velo-cardio-facial syndrome)?
    Linda E Campbell
    Institute of Psychiatry, King s College London, University of London, London, UK
    J Neurodev Disord 3:152-61. 2011
    ..These results are discussed in relation to the importance of a better delineation of social competence in this population...
  25. doi request reprint Is there a common underlying mechanism for age-related decline in cortical thickness?
    Christine Ecker
    Section of Brain Maturation, PO50, Institute of Psychiatry, De Crespigny Park, London SE58AF, UK
    Neuroreport 20:1155-60. 2009
    ..This model reconciles two seemingly mutually exclusive hypotheses, namely, the existence of different decay functions being caused by the same underlying mechanism...
  26. doi request reprint Microstructural organization of cerebellar tracts in schizophrenia
    Richard A A Kanaan
    Department of Psychological Medicine, Institute of Psychiatry, London, United Kingdom
    Biol Psychiatry 66:1067-9. 2009
    ..However, previous studies have employed region-of-interest approaches or have used small or unmatched samples, with a consequent risk of type II error...
  27. doi request reprint A functional magnetic resonance imaging study of inhibitory control in obsessive-compulsive disorder
    Lisa A Page
    King s College London, Division of Psychological Medicine and Psychiatry, Institute of Psychiatry, Room 3 14, Weston Education Centre, 10 Cutcombe Road, London, SE5 9RJ, UK
    Psychiatry Res 174:202-9. 2009
    ..OCD is associated with task-relevant fronto-striatal dysfunction during motor inhibition and cognitive switching. In addition, parieto-temporal dysfunction was observed during tasks with a higher attentional load...
  28. ncbi request reprint The Women's Health Initiative Memory Study: findings and implications for treatment
    Michael C Craig
    Psychological Medicine, Institute of Psychiatry, London, UK
    Lancet Neurol 4:190-4. 2005
    ..There has been extensive media coverage of these trials and many doctors are asked whether HT improves or worsens brain function in younger women who are prescribed HT for the treatment of menopausal symptoms...
  29. doi request reprint Describing the brain in autism in five dimensions--magnetic resonance imaging-assisted diagnosis of autism spectrum disorder using a multiparameter classification approach
    Christine Ecker
    Section of Brain Maturation, Department of Psychological Medicine, Institute of Psychiatry, Brain Image Analysis Unit, Centre for Neuroimaging Sciences, King s College, London SE5 8AF, United Kingdom
    J Neurosci 30:10612-23. 2010
    ..The spatial patterns detected using SVM may help further exploration of the specific genetic and neuropathological underpinnings of ASD, and provide new insights into the most likely multifactorial etiology of the condition...
  30. doi request reprint Altered cerebellar feedback projections in Asperger syndrome
    Marco Catani
    Section of Brain Maturation, Department of Psychological Medicine and Psychiatry, Institute of Psychiatry, King s College London, London, SE58AF, UK
    Neuroimage 41:1184-91. 2008
    ..The localised abnormalities in the main cerebellar outflow pathway may prevent the cerebral cortex from receiving those cerebellar feedback inputs necessary for a successful adaptive social behaviour...
  31. doi request reprint Serotonin transporter genotype and neuroanatomy in autism spectrum disorders
    Armin Raznahan
    Department of Child and Adolescent Psychiatry, Institute of Psychiatry, KCL, UK
    Psychiatr Genet 19:147-50. 2009
    ....
  32. ncbi request reprint Women with autistic-spectrum disorder: magnetic resonance imaging study of brain anatomy
    Michael C Craig
    PO Box 50, Institute of Psychiatry, De Crespigny Park, Denmark Hill, London SE5 8AF, UK
    Br J Psychiatry 191:224-8. 2007
    ..Our understanding of anatomical differences in people with autistic-spectrum disorder, is based on mixed-gender or male samples...
  33. ncbi request reprint Cortical serotonin 5-HT2A receptor binding and social communication in adults with Asperger's syndrome: an in vivo SPECT study
    Declan G M Murphy
    Institute of Psychiatry, Department of Psychological Medicine, London, UK
    Am J Psychiatry 163:934-6. 2006
    ..e., autism and Asperger's syndrome) is unknown. The serotonergic (5-HT) system may be especially implicated. However, cortical 5-HT2A receptor density in adults with the disorder has not been examined, to the authors' knowledge...
  34. ncbi request reprint Effects of acute ovarian hormone suppression on the human brain: an in vivo 1H MRS study
    Michael C Craig
    Department of Psychological Medicine, Institute of Psychiatry, Section of Brain Maturation, London, UK
    Psychoneuroendocrinology 32:1128-32. 2007
    ..They also showed a trend to a significant increase in Cho concentration in the hippocampus. This supports our previous findings and adds to the evidence that neuronal/glial membrane metabolism is affected by sex hormones in women...
  35. ncbi request reprint Brain and behaviour in children with 22q11.2 deletion syndrome: a volumetric and voxel-based morphometry MRI study
    Linda E Campbell
    King s College London, Institute of Psychiatry, London, UK
    Brain 129:1218-28. 2006
    ..We suggest that there is preliminary evidence for specific vulnerability of the frontostriatal and cerebellar-cortical networks in 22qDS...
  36. ncbi request reprint Gonadotropin hormone releasing hormone agonists alter prefrontal function during verbal encoding in young women
    Michael C Craig
    Section of Brain Maturation PO50, Department of Psychological Medicine, Institute of Psychiatry, 16 De Crespigny Park, Denmark Hill, London SE5 8AF, UK
    Psychoneuroendocrinology 32:1116-27. 2007
    ....
  37. ncbi request reprint 5-HT, prefrontal function and aging: fMRI of inhibition and acute tryptophan depletion
    Melissa Lamar
    Department of Psychology, Institute of Psychiatry, King s College London, London, UK
    Neurobiol Aging 30:1135-46. 2009
    ..Maintaining successful Simon performance during ATD is achieved by increasing cerebellar and parietal contributions to compensate for decreased fronto-cingulo-striatal involvement...
  38. doi request reprint Changes in male brain responses to emotional faces from adolescence to middle age
    Quinton Deeley
    Section of Brain Maturation, King s College London Institute of Psychiatry, De Crespigny Park, London, UK
    Neuroimage 40:389-97. 2008
    ....
  39. ncbi request reprint Influence of X chromosome and hormones on human brain development: a magnetic resonance imaging and proton magnetic resonance spectroscopy study of Turner syndrome
    William J Cutter
    Section of Brain Maturation, Department of Psychological Medicine, Institute of Psychiatry, De Crespigny Park, Denmark Hill, London SE5 8AF, UK
    Biol Psychiatry 59:273-83. 2006
    ..Hence, they allow us an opportunity to investigate genetic and endocrine influences on brain development...
  40. doi request reprint Physiological variation in estradiol and brain function: a functional magnetic resonance imaging study of verbal memory across the follicular phase of the menstrual cycle
    Michael C Craig
    Section of Brain Maturation PO50, Department of Psychological Medicine, Institute of Psychiatry, Kings College, London, SE5 8AF, UK
    Horm Behav 53:503-8. 2008
    ..Although we did not find a significant relationship between plasma estradiol concentration and verbal recall performance, we report a positive correlation between brain function and estradiol concentration at the LIFG...
  41. ncbi request reprint Obsessions and compulsions in Asperger syndrome and high-functioning autism
    Ailsa J Russell
    Department of Psychology, Institute of Psychiatry, King s College, London, UK
    Br J Psychiatry 186:525-8. 2005
    ..Obsessive-compulsive behaviours are common and disabling in autistic-spectrum disorders (ASD) but little is known about how they compare with those experienced by people with obsessive-compulsive disorder (OCD)...
  42. doi request reprint A study of visuospatial working memory pre- and post-Gonadotropin Hormone Releasing Hormone agonists (GnRHa) in young women
    Michael C Craig
    Section of Brain Maturation PO50, Department of Psychological Medicine, Institute of Psychiatry, King s College, London, UK
    Horm Behav 54:47-59. 2008
    ..Our study suggests that acute ovarian hormone withdrawal following GnRHa, and perhaps at other times, (e.g. following surgical menopause and postpartum) alters the neural circuitry underlying performance of VWM...
  43. ncbi request reprint Asperger syndrome: a proton magnetic resonance spectroscopy study of brain
    Declan G M Murphy
    Department of Psychological Medicine, St George s Hospital Medical School, London, England
    Arch Gen Psychiatry 59:885-91. 2002
    ..Nobody has examined the relationship between abnormalities in the frontal and parietal lobes and clinical symptoms in people with AS...
  44. doi request reprint Alzheimer's disease in women
    Michael C Craig
    Section of Brain Maturation PO50, Department of Psychological Medicine, Institute of Psychiatry, De Crespigny Park, Denmark Hill, London SE5 8AF, UK
    Best Pract Res Clin Obstet Gynaecol 23:53-61. 2009
    ..However, it may have a negative or neutral effect if it is prescribed to women after this time. This chapter will discuss some of the putative biological mechanisms that may underlie these effects...
  45. ncbi request reprint A neuropsychological investigation of male premutation carriers of fragile X syndrome
    Caroline J Moore
    Division of Psychological Medicine, Section of Brain Maturation, Institute of Psychiatry, King s College London, DeCrespigny Park, London, UK
    Neuropsychologia 42:1934-47. 2004
    ....
  46. doi request reprint Reversibility of the effects of acute ovarian hormone suppression on verbal memory and prefrontal function in pre-menopausal women
    Michael C Craig
    Section of Brain Maturation PO50, Department of Psychological Medicine, Institute of Psychiatry, De Crespigny Park, Denmark Hill, London SE5 8AF, UK
    Psychoneuroendocrinology 33:1426-31. 2008
    ..To do this we carried out a further imaging study using the same verbal memory recognition task after cessation of GnRHa-induced ovarian suppression...
  47. ncbi request reprint Oestrogen: brain ageing, cognition and neuropsychiatric disorder
    Ray Norbury
    Section of Brain Maturation, Department of Psychological Medicine, Institute of Psychiatry, De Crespigny Park, London, UK
    J Br Menopause Soc 10:118-22. 2004
    ..Here we review research into the effects of oestrogen on brain maturation and function and discuss the role for oestrogen replacement therapy (ERT) as a therapeutic tool...
  48. doi request reprint The interactive effect of the cholinergic system and acute ovarian suppression on the brain: an fMRI study
    M C Craig
    Department of Psychological Medicine, Section of Brain Maturation, Institute of Psychiatry, Kings College London, Denmark Hill, London, UK
    Horm Behav 55:41-9. 2009
    ..Furthermore, this interaction may provide a useful model to help explain reports of increased risk for cognitive decline and AD in women following ovariectomy...
  49. ncbi request reprint People with learning disabilities in a low secure in-patient unit: comparison of offenders and non-offenders
    Suzie Reed
    Maudsley Centre for Behavioural Disorders, South London and Maudsley NHS Trust, and Health Services Research Department, Institute of Psychiatry, London SE5 8AF, UK
    Br J Psychiatry 185:499-504. 2004
    ....
  50. ncbi request reprint Neuropsychological functioning in adults with Asperger syndrome
    Fiona Z Ambery
    Department of Psychological Medicine, Institute of Psychiatry, London, UK
    Autism 10:551-64. 2006
    ..There was no significant difference between verbal and performance IQ. Our results suggest that impairments on tests requiring flexibility of thought and generation occur at all ages and across a range of autistic disorders including AS...
  51. pmc A functional polymorphism of the brain derived neurotrophic factor gene and cortical anatomy in autism spectrum disorder
    Armin Raznahan
    Department of Child and Adolescent Psychiatry, Institute of Psychiatry IOP, Kings College London KCL, 16 De Crespigny Park, London, SE5 8AF, UK
    J Neurodev Disord 1:215-23. 2009
    ..If correct, this suggests ASD is associated with a distorted relationship between BDNF val66met genotype and the determinants of regional cortical surface area - gyrification and/or sulcal positioning...
  52. ncbi request reprint Hippocampal myo-inositol and cognitive ability in adults with Down syndrome: an in vivo proton magnetic resonance spectroscopy study
    Felix Beacher
    Section of Brain Maturation, Department of Psychological Medicine, Neuroimaging Research Group, Institute of Psychiatry, De Crespigny Park, Denmark Hill, London SE5 8AF, England, UK
    Arch Gen Psychiatry 62:1360-5. 2005
    ..The serum sodium/myo-inositol cotransporter gene is located on chromosome 21, and myo-inositol affects neuronal survival and function. Nevertheless, few in vivo studies have examined the role of myo-inositol in DS...
  53. doi request reprint Comparison of ICD-10R, DSM-IV-TR and DSM-5 in an adult autism spectrum disorder diagnostic clinic
    C Ellie Wilson
    Department of Forensic and Neurodevelopmental Science, Institute of Psychiatry, King s College, London, SE5 8AF, UK
    J Autism Dev Disord 43:2515-25. 2013
    ..Reduced rates of ASD diagnosis may mean some ASD individuals will be unable to access clinical services. ..
  54. pmc Visuospatial working memory in children and adolescents with 22q11.2 deletion syndrome; an fMRI study
    Rayna Azuma
    Psychological Medicine, Institute of Psychiatry, King s College London, Section of Brain Maturation PO50, DeCrespigny Park, London, SE5 8AF, UK
    J Neurodev Disord 1:46-60. 2009
    ..Genetically determined differences in the development of specific brain systems may underpin the cognitive deficits in 22q11DS, and may contribute to the later development of neuropsychiatric disorders...
  55. doi request reprint The interactive effect of acute ovarian suppression and the cholinergic system on visuospatial working memory in young women
    M C Craig
    Department of Psychological Medicine, Institute of Psychiatry, Kings College London, London, United Kingdom
    Psychoneuroendocrinology 35:987-1000. 2010
    ..Overall, our findings point to a neural network by which acute loss of ovarian function may interact to negatively impact encoding...
  56. doi request reprint Atlasing location, asymmetry and inter-subject variability of white matter tracts in the human brain with MR diffusion tractography
    Michel Thiebaut de Schotten
    Natbrainlab, Department of Forensic and Neurodevelopmental Sciences, Institute of Psychiatry, King s College London, London, UK
    Neuroimage 54:49-59. 2011
    ..This study suggests that DTI-derived maps can be used together with a previous histological atlas to establish the relationship of focal lesions with nearby tracts and improve clinico-anatomical correlation...
  57. doi request reprint In vivo brain anatomy of adult males with Fragile X syndrome: an MRI study
    Brian P Hallahan
    Department of Psychological Medicine, Institute of Psychiatry, King s College, London, UK
    Neuroimage 54:16-24. 2011
    ..People with FraX have regionally specific differences in brain anatomy from healthy controls with enlargement of the caudate nuclei that persists into adulthood...
  58. doi request reprint A comparative study of cognition and brain anatomy between two neurodevelopmental disorders: 22q11.2 deletion syndrome and Williams syndrome
    Linda E Campbell
    Section of Brain Maturation, Institute of Psychiatry, King s College London, UK
    Neuropsychologia 47:1034-44. 2009
    ..Hence, it is difficult to know if the observed features of 22q11DS are simply due to a non-specific effect of having a genetic disorder or are specific to 22q11DS...
  59. doi request reprint Brain structural differences associated with the behavioural phenotype in children with Williams syndrome
    Linda E Campbell
    King s College London, Institute of Psychiatry, UK
    Brain Res 1258:96-107. 2009
    ..We investigated structural brain morphology of intellectually disabled children with Williams (WS) syndrome and its relationship to the behavioural phenotype...
  60. doi request reprint Brain anatomy and its relationship to behavior in adults with autism spectrum disorder: a multicenter magnetic resonance imaging study
    Christine Ecker
    Department of Forensic and Neurodevelopmental Sciences, Institute of Psychiatry, De Crespigny Park, London, England
    Arch Gen Psychiatry 69:195-209. 2012
    ..There is consensus that autism spectrum disorder (ASD) is accompanied by differences in neuroanatomy. However, the neural substrates of ASD during adulthood, as well as how these relate to behavioral variation, remain poorly understood...
  61. doi request reprint Effects of acute tryptophan depletion on neural processing of facial expressions of emotion in humans
    Eileen Daly
    Section of Brain Maturation, Department of Psychological Medicine and Psychiatry, Institute of Psychiatry, King s College London, London, UK
    Psychopharmacology (Berl) 210:499-510. 2010
    ..Acute tryptophan depletion (ATD) temporarily lowers brain serotonin (5-HT) synthesis, and behavioral studies have shown that this alters the processing of facial expressions of emotion...
  62. doi request reprint Mapping infant brain myelination with magnetic resonance imaging
    Sean C L Deoni
    Centre for Neuroimaging Sciences, Institute of Psychiatry, London SE5 8AF, UK
    J Neurosci 31:784-91. 2011
    ..This work represents a significant step forward in our ability to appreciate the fundamental process of myelination, and provides the first ever in vivo visualization of myelin maturation in healthy human infancy...
  63. doi request reprint Cortical anatomy in autism spectrum disorder: an in vivo MRI study on the effect of age
    Armin Raznahan
    Department of Child and Adolescent Psychiatry, Institute of Psychiatry, King s College London, London, UK
    Cereb Cortex 20:1332-40. 2010
    ..This may reflect primary abnormalities in cortical plasticity and/or be secondary to disturbed interactions between individuals with ASD and their environment...