D G Murphy

Summary

Affiliation: King's College London
Country: UK

Publications

  1. ncbi request reprint Asperger syndrome: a proton magnetic resonance spectroscopy study of brain
    Declan G M Murphy
    Department of Psychological Medicine, St George s Hospital Medical School, London, England
    Arch Gen Psychiatry 59:885-91. 2002
  2. ncbi request reprint Premutation female carriers of fragile X syndrome: a pilot study on brain anatomy and metabolism
    D G Murphy
    Department of Psychological Medicine, Institute of Psychiatry, London, England
    J Am Acad Child Adolesc Psychiatry 38:1294-301. 1999
  3. ncbi request reprint Cortical serotonin 5-HT2A receptor binding and social communication in adults with Asperger's syndrome: an in vivo SPECT study
    Declan G M Murphy
    Institute of Psychiatry, Department of Psychological Medicine, London, UK
    Am J Psychiatry 163:934-6. 2006
  4. pmc Reduced subcortical glutamate/glutamine in adults with autism spectrum disorders: a [¹H]MRS study
    J Horder
    Institute of Psychiatry, Department of Forensic and Neurodevelopmental Sciences, King s College London, London, UK
    Transl Psychiatry 3:e279. 2013
  5. pmc Disorder-specific functional abnormalities during sustained attention in youth with Attention Deficit Hyperactivity Disorder (ADHD) and with autism
    A Christakou
    Department of Child and Adolescent Psychiatry, Institute of Psychiatry, King s College London, London, UK
    Mol Psychiatry 18:236-44. 2013
  6. ncbi request reprint Structural brain abnormalities associated with deletion at chromosome 22q11: quantitative neuroimaging study of adults with velo-cardio-facial syndrome
    T van Amelsvoort
    Department of Psychological Medicine, Institute of Psychiatry, London, UK
    Br J Psychiatry 178:412-9. 2001
  7. ncbi request reprint Estrogen: effects on normal brain function and neuropsychiatric disorders
    M C Craig
    Section of Brain Maturation, Department of Psychological Medicine, Institute of Psychiatry, London, UK
    Climacteric 10:97-104. 2007
  8. ncbi request reprint SPET imaging of central muscarinic receptors with (R,R)[123I]-I-QNB: methodological considerations
    R Norbury
    Psychological Medicine, Institute of Psychiatry, Denmark Hill, London, United Kingdom
    Nucl Med Biol 31:583-90. 2004
  9. ncbi request reprint Oestrogen, cognition and the maturing female brain
    M C Craig
    Section of Brain Maturation, Department of Psychological Medicine, Institute of Psychiatry, 16 De Crespigny Park, London, UK
    J Neuroendocrinol 19:1-6. 2007
  10. doi request reprint Investigating the predictive value of whole-brain structural MR scans in autism: a pattern classification approach
    Christine Ecker
    Section of Brain Maturation, Department of Psychological Medicine, Institute of Psychiatry, King s College, London, UK
    Neuroimage 49:44-56. 2010

Detail Information

Publications16

  1. ncbi request reprint Asperger syndrome: a proton magnetic resonance spectroscopy study of brain
    Declan G M Murphy
    Department of Psychological Medicine, St George s Hospital Medical School, London, England
    Arch Gen Psychiatry 59:885-91. 2002
    ..Nobody has examined the relationship between abnormalities in the frontal and parietal lobes and clinical symptoms in people with AS...
  2. ncbi request reprint Premutation female carriers of fragile X syndrome: a pilot study on brain anatomy and metabolism
    D G Murphy
    Department of Psychological Medicine, Institute of Psychiatry, London, England
    J Am Acad Child Adolesc Psychiatry 38:1294-301. 1999
    ..Thus the authors investigated brain structure and metabolism in premutation carriers of FraX...
  3. ncbi request reprint Cortical serotonin 5-HT2A receptor binding and social communication in adults with Asperger's syndrome: an in vivo SPECT study
    Declan G M Murphy
    Institute of Psychiatry, Department of Psychological Medicine, London, UK
    Am J Psychiatry 163:934-6. 2006
    ..e., autism and Asperger's syndrome) is unknown. The serotonergic (5-HT) system may be especially implicated. However, cortical 5-HT2A receptor density in adults with the disorder has not been examined, to the authors' knowledge...
  4. pmc Reduced subcortical glutamate/glutamine in adults with autism spectrum disorders: a [¹H]MRS study
    J Horder
    Institute of Psychiatry, Department of Forensic and Neurodevelopmental Sciences, King s College London, London, UK
    Transl Psychiatry 3:e279. 2013
    ..In conclusion, individuals across the spectrum of ASD have regionally specific abnormalities in subcortical glutamatergic neurotransmission that are associated with variation in social development...
  5. pmc Disorder-specific functional abnormalities during sustained attention in youth with Attention Deficit Hyperactivity Disorder (ADHD) and with autism
    A Christakou
    Department of Child and Adolescent Psychiatry, Institute of Psychiatry, King s College London, London, UK
    Mol Psychiatry 18:236-44. 2013
    ..Shared deficits were in fronto-striato-parietal activation and default mode suppression. Differences were a more severe DLPFC dysfunction in ADHD and a disorder-specific fronto-striato-cerebellar dysregulation in ASD...
  6. ncbi request reprint Structural brain abnormalities associated with deletion at chromosome 22q11: quantitative neuroimaging study of adults with velo-cardio-facial syndrome
    T van Amelsvoort
    Department of Psychological Medicine, Institute of Psychiatry, London, UK
    Br J Psychiatry 178:412-9. 2001
    ..Velo-cardio-facial syndrome (VCFS) is associated with deletions in the qll band of chromosome 22, learning disability and psychosis, but the neurobiological basis is poorly understood...
  7. ncbi request reprint Estrogen: effects on normal brain function and neuropsychiatric disorders
    M C Craig
    Section of Brain Maturation, Department of Psychological Medicine, Institute of Psychiatry, London, UK
    Climacteric 10:97-104. 2007
    ....
  8. ncbi request reprint SPET imaging of central muscarinic receptors with (R,R)[123I]-I-QNB: methodological considerations
    R Norbury
    Psychological Medicine, Institute of Psychiatry, Denmark Hill, London, United Kingdom
    Nucl Med Biol 31:583-90. 2004
    ..Here we show that, for this radiotracer, normalizing to a region of negligible specific binding (cerebellum) significantly improves sensitivity when compared to global normalization...
  9. ncbi request reprint Oestrogen, cognition and the maturing female brain
    M C Craig
    Section of Brain Maturation, Department of Psychological Medicine, Institute of Psychiatry, 16 De Crespigny Park, London, UK
    J Neuroendocrinol 19:1-6. 2007
    ..Here, we review the evidence that, in healthy women, ovarian steroids/oestrogen affects brain regions crucial to higher cognitive function at the macroscopic, microscopic, functional and neurotransmitter levels...
  10. doi request reprint Investigating the predictive value of whole-brain structural MR scans in autism: a pattern classification approach
    Christine Ecker
    Section of Brain Maturation, Department of Psychological Medicine, Institute of Psychiatry, King s College, London, UK
    Neuroimage 49:44-56. 2010
    ..Also, these differences provide significant predictive power for group membership, which is related to symptom severity...
  11. doi request reprint A structural MRI study of motor conversion disorder: evidence of reduction in thalamic volume
    T R Nicholson
    Section of Cognitive Neuropsychiatry, Institute of Psychiatry, King s College London, London, UK
    J Neurol Neurosurg Psychiatry 85:227-9. 2014
    ..To investigate potential abnormalities in subcortical brain structures in conversion disorder (CD) compared with controls using a region of interest (ROI) approach...
  12. pmc Glutamate/glutamine and neuronal integrity in adults with ADHD: a proton MRS study
    S Maltezos
    1 Adult ADHD Service, The Maudsley Hospital, London, UK 2 King s College London, Department of Forensic and Neurodevelopmental Sciences, Institute of Psychiatry, London, UK
    Transl Psychiatry 4:e373. 2014
    ..We suggest that subcortical glutamate and glutamine have a modulatory role in ADHD adults; and that differences in glutamate-glutamine levels are not explained by use of stimulant medication. ..
  13. ncbi request reprint An inpatient treatment model for adults with mild intellectual disability and challenging behaviour
    K I Xenitidis
    The Maudsley and Bethlem Royal NHS Trust, and Department of Psychological Medicine, Institute of Psychiatry, London, UK
    J Intellect Disabil Res 43:128-34. 1999
    ..0001). It is concluded that the MIETS is an effective treatment model for people with ID and CB, and that there is no place for therapeutic nihilism in this difficult-to-place group of patients...
  14. doi request reprint Anatomy and aging of the amygdala and hippocampus in autism spectrum disorder: an in vivo magnetic resonance imaging study of Asperger syndrome
    Clodagh M Murphy
    King s College London, Institute of Psychiatry, Department of Forensic and Neurodevelopmental Science, London, United Kingdom
    Autism Res 5:3-12. 2012
    ..97, z = 1.995). There were no significant group differences in volume or age-related effects in hippocampus. Individuals with Asperger syndrome have significant differences from controls in bulk volume and aging of the amygdala...
  15. ncbi request reprint Effects of estrogen replacement therapy on human brain aging: an in vivo 1H MRS study
    D M Robertson
    Department of Psychological Medicine, Institute of Psychiatry, London, UK
    Neurology 57:2114-7. 2001
    ..Cho reflects increased neuronal/glial membrane turnover. Thus, ERT's "neuroprotective" effect may include modulating the effects of age on neural integrity in brain regions involved in cognitive function...
  16. ncbi request reprint Prolactin response to d-fenfluramine in postmenopausal women on and off ERT: comparison with young women
    T A van Amelsvoort
    Department of Psychological Medicine, Institute of Psychiatry, De Crespigny Park, SE5 8AF, London, UK
    Psychoneuroendocrinology 26:493-502. 2001
    ..Estrogen may modulate age-related changes in 5-HT tone. This may partly explain why estrogen can decrease vulnerability to mood disorders and cognitive changes in postmenopausal women...