James Monypenny

Summary

Affiliation: King's College London
Country: UK

Publications

  1. pmc Cdc42 and Rac family GTPases regulate mode and speed but not direction of primary fibroblast migration during platelet-derived growth factor-dependent chemotaxis
    James Monypenny
    Department of Pharmacology, Kyoto University Faculty of Medicine, Yosida Konoe cho, Sakyo ku, Kyoto 606 8501, Japan
    Mol Cell Biol 29:2730-47. 2009
  2. doi request reprint G-actin regulates rapid induction of actin nucleation by mDia1 to restore cellular actin polymers
    Chiharu Higashida
    Department of Pharmacology, Kyoto University Faculty of Medicine, Yoshida konoe cho, Sakyo ku, Kyoto 606 8501, Japan
    J Cell Sci 121:3403-12. 2008
  3. ncbi request reprint Actin polymerization-driven molecular movement of mDia1 in living cells
    Chiharu Higashida
    Department of Pharmacology, Kyoto University Faculty of Medicine, Yoshida konoe cho, Sakyo ku, Kyoto, Japan
    Science 303:2007-10. 2004
  4. pmc The Rho-mDia1 pathway regulates cell polarity and focal adhesion turnover in migrating cells through mobilizing Apc and c-Src
    Norikazu Yamana
    Department of Pharmacology, Kyoto University Faculty of Medicine, Kyoto 606 8501, Japan
    Mol Cell Biol 26:6844-58. 2006

Collaborators

  • Shuh Narumiya
  • Naoki Watanabe
  • Shiro Suetsugu
  • Chiharu Higashida
  • Norikazu Yamana
  • Takahiro Tsuji
  • Yoshiki Arakawa
  • Nobuo Hashimoto
  • Michiyuki Matsuda
  • Toshimasa Ishizaki
  • Kazuhiko Nozaki
  • Reina E Itoh
  • Masahiro Tanji
  • Tomohiro Nishino
  • Haruhiko Bito
  • Kazuo Kurokawa
  • Takushi Miyoshi
  • Yoshikazu Andou
  • Fabian Oceguera-Yanez
  • Akiko Fujita

Detail Information

Publications4

  1. pmc Cdc42 and Rac family GTPases regulate mode and speed but not direction of primary fibroblast migration during platelet-derived growth factor-dependent chemotaxis
    James Monypenny
    Department of Pharmacology, Kyoto University Faculty of Medicine, Yosida Konoe cho, Sakyo ku, Kyoto 606 8501, Japan
    Mol Cell Biol 29:2730-47. 2009
    ....
  2. doi request reprint G-actin regulates rapid induction of actin nucleation by mDia1 to restore cellular actin polymers
    Chiharu Higashida
    Department of Pharmacology, Kyoto University Faculty of Medicine, Yoshida konoe cho, Sakyo ku, Kyoto 606 8501, Japan
    J Cell Sci 121:3403-12. 2008
    ..Taken together, we propose that transient accumulation of G-actin works as a cue to promote mDia1-catalyzed actin nucleation to execute rapid reassembly of actin filaments...
  3. ncbi request reprint Actin polymerization-driven molecular movement of mDia1 in living cells
    Chiharu Higashida
    Department of Pharmacology, Kyoto University Faculty of Medicine, Yoshida konoe cho, Sakyo ku, Kyoto, Japan
    Science 303:2007-10. 2004
    ..mDia1 probably moves processively along the growing end of actin filaments in cells, and Formins may be a molecular motility machinery that is independent from motor proteins...
  4. pmc The Rho-mDia1 pathway regulates cell polarity and focal adhesion turnover in migrating cells through mobilizing Apc and c-Src
    Norikazu Yamana
    Department of Pharmacology, Kyoto University Faculty of Medicine, Kyoto 606 8501, Japan
    Mol Cell Biol 26:6844-58. 2006
    ..Thus, the Rho-mDia1 pathway regulates polarization and adhesion turnover by aligning microtubules and actin filaments and delivering Apc/Cdc42 and c-Src to their respective sites of action...