James Monypenny

Summary

Affiliation: King's College London
Country: UK

Publications

  1. ncbi Cdc42 and Rac family GTPases regulate mode and speed but not direction of primary fibroblast migration during platelet-derived growth factor-dependent chemotaxis
    James Monypenny
    Department of Pharmacology, Kyoto University Faculty of Medicine, Yosida Konoe cho, Sakyo ku, Kyoto 606 8501, Japan
    Mol Cell Biol 29:2730-47. 2009
  2. ncbi G-actin regulates rapid induction of actin nucleation by mDia1 to restore cellular actin polymers
    Chiharu Higashida
    Department of Pharmacology, Kyoto University Faculty of Medicine, Yoshida konoe cho, Sakyo ku, Kyoto 606 8501, Japan
    J Cell Sci 121:3403-12. 2008
  3. ncbi Actin polymerization-driven molecular movement of mDia1 in living cells
    Chiharu Higashida
    Department of Pharmacology, Kyoto University Faculty of Medicine, Yoshida konoe cho, Sakyo ku, Kyoto, Japan
    Science 303:2007-10. 2004
  4. ncbi The Rho-mDia1 pathway regulates cell polarity and focal adhesion turnover in migrating cells through mobilizing Apc and c-Src
    Norikazu Yamana
    Department of Pharmacology, Kyoto University Faculty of Medicine, Kyoto 606 8501, Japan
    Mol Cell Biol 26:6844-58. 2006

Collaborators

  • Shuh Narumiya
  • Naoki Watanabe
  • Shiro Suetsugu
  • Chiharu Higashida
  • Norikazu Yamana
  • Takahiro Tsuji
  • Kazuo Kurokawa
  • Masahiro Tanji
  • Nobuo Hashimoto
  • Haruhiko Bito
  • Reina E Itoh
  • Michiyuki Matsuda
  • Kazuhiko Nozaki
  • Yoshiki Arakawa
  • Tomohiro Nishino
  • Toshimasa Ishizaki
  • Akiko Fujita
  • Fabian Oceguera-Yanez
  • Takushi Miyoshi
  • Yoshikazu Andou

Detail Information

Publications4

  1. ncbi Cdc42 and Rac family GTPases regulate mode and speed but not direction of primary fibroblast migration during platelet-derived growth factor-dependent chemotaxis
    James Monypenny
    Department of Pharmacology, Kyoto University Faculty of Medicine, Yosida Konoe cho, Sakyo ku, Kyoto 606 8501, Japan
    Mol Cell Biol 29:2730-47. 2009
    ....
  2. ncbi G-actin regulates rapid induction of actin nucleation by mDia1 to restore cellular actin polymers
    Chiharu Higashida
    Department of Pharmacology, Kyoto University Faculty of Medicine, Yoshida konoe cho, Sakyo ku, Kyoto 606 8501, Japan
    J Cell Sci 121:3403-12. 2008
    ..Taken together, we propose that transient accumulation of G-actin works as a cue to promote mDia1-catalyzed actin nucleation to execute rapid reassembly of actin filaments...
  3. ncbi Actin polymerization-driven molecular movement of mDia1 in living cells
    Chiharu Higashida
    Department of Pharmacology, Kyoto University Faculty of Medicine, Yoshida konoe cho, Sakyo ku, Kyoto, Japan
    Science 303:2007-10. 2004
    ..mDia1 probably moves processively along the growing end of actin filaments in cells, and Formins may be a molecular motility machinery that is independent from motor proteins...
  4. ncbi The Rho-mDia1 pathway regulates cell polarity and focal adhesion turnover in migrating cells through mobilizing Apc and c-Src
    Norikazu Yamana
    Department of Pharmacology, Kyoto University Faculty of Medicine, Kyoto 606 8501, Japan
    Mol Cell Biol 26:6844-58. 2006
    ..Thus, the Rho-mDia1 pathway regulates polarization and adhesion turnover by aligning microtubules and actin filaments and delivering Apc/Cdc42 and c-Src to their respective sites of action...