Research Topics
| David Mataix-ColsSummaryAffiliation: King's College London Country: UK Publications
| Collaborators
|
Detail Information
Publications
The London field trial for hoarding disorderD Mataix-Cols
Department of Psychosis Studies, King s College London, Institute of Psychiatry, London, UK
Psychol Med 43:837-47. 2013..Participants were asked about their perceptions of the acceptability, utility and stigma associated with the new diagnosis...- Annual research review: hoarding disorder: potential benefits and pitfalls of a new mental disorderDavid Mataix-Cols
Departments of Psychosis Studies and Psychology, King s College London, Institute of Psychiatry, London, UK
J Child Psychol Psychiatry 53:608-18. 2012..Given the proposed inclusion of a new hoarding disorder (HD) in DSM-5 (Diagnostic and Statistical Manual of Mental Disorders, fifth edition), it is pertinent to discuss the potential benefits and pitfalls of such a development... - Hoarding disorder: a new diagnosis for DSM-V?David Mataix-Cols
King s College London, Institute of Psychiatry, London, United Kingdom
Depress Anxiety 27:556-72. 2010..The creation of a new diagnosis in DSM-V would likely increase public awareness, improve identification of cases, and stimulate both research and the development of specific treatments for hoarding disorder... - Neuropsychological and neural correlates of hoarding: a practice-friendly reviewDavid Mataix-Cols
Department of Psychosis Studies, King s College London, Institute of Psychiatry, PO 69, De Crespigny Park Road, London SE5 8AF, United Kingdom
J Clin Psychol 67:467-76. 2011..Although not possible to establish firm conclusions at this stage, we conclude with a series of observations and recommendations for clinical practice... - Individual differences in disgust sensitivity modulate neural responses to aversive/disgusting stimuliDavid Mataix-Cols
King s College London, Institute of Psychiatry, London, UK
Eur J Neurosci 27:3050-8. 2008..The results have implications for disgust-related psychiatric disorders... 
Distinct neural correlates of washing, checking, and hoarding symptom dimensions in obsessive-compulsive disorderDavid Mataix-Cols
Department of Psychological Medicine, Institute of Psychiatry, London, England
Arch Gen Psychiatry 61:564-76. 2004....- Refining the diagnostic boundaries of compulsive hoarding: a critical reviewAlberto Pertusa
Division of Psychological Medicine, King s College London, Institute of Psychiatry, London, UK
Clin Psychol Rev 30:371-86. 2010..Growing evidence from epidemiological, phenomenological, neurobiological, and treatment studies suggests that compulsive hoarding may be best classified as a discrete disorder with its own diagnostic criteria... - Stressful life events and material deprivation in hoarding disorderDanielle Landau
King s College London, Institute of Psychiatry, London, England, United Kingdom
J Anxiety Disord 25:192-202. 2011.... - Meta-analysis of functional magnetic resonance imaging studies of inhibition and attention in attention-deficit/hyperactivity disorder: exploring task-specific, stimulant medication, and age effectsHeledd Hart
Department of Child and Adolescent Psychiatry, Institute of Psychiatry, King s College London, London, England
JAMA Psychiatry 70:185-98. 2013..Furthermore, preliminary evidence suggests that long-term stimulant medication use may be associated with more normal activation in right caudate during the attention domain... - Compulsive hoarding: OCD symptom, distinct clinical syndrome, or both?Alberto Pertusa
Division of Psychological Medicine, King s College London, Institute of Psychiatry, PO 69, De Crespigny Park Rd, London SE58AF, United Kingdom
Am J Psychiatry 165:1289-98. 2008..Compulsive hoarding is a debilitating problem that is often associated with obsessive-compulsive disorder (OCD) and obsessive-compulsive personality disorder. However, the precise nosology of compulsive hoarding has yet to be determined... - A functional magnetic resonance imaging study of inhibitory control in obsessive-compulsive disorderLisa A Page
King s College London, Division of Psychological Medicine and Psychiatry, Institute of Psychiatry, Room 3 14, Weston Education Centre, 10 Cutcombe Road, London, SE5 9RJ, UK
Psychiatry Res 174:202-9. 2009..OCD is associated with task-relevant fronto-striatal dysfunction during motor inhibition and cognitive switching. In addition, parieto-temporal dysfunction was observed during tasks with a higher attentional load... - Prevalence and heritability of skin picking in an adult community sample: a twin studyBenedetta Monzani
Department of Psychosis Studies, King s College London, Institute of Psychiatry, London, UK
Am J Med Genet B Neuropsychiatr Genet 159:605-10. 2012..Non-shared environmental factors are also likely to play an important role in its etiology... - Children with very early onset obsessive-compulsive disorder: clinical features and treatment outcomeEriko Nakatani
King s College London, Institute of Psychiatry, London, UK
J Child Psychol Psychiatry 52:1261-8. 2011..The present study represents the first investigation into the effect of age at onset of OCD on clinical characteristics and response to treatment in a paediatric sample... - Meta-analytical comparison of voxel-based morphometry studies in obsessive-compulsive disorder vs other anxiety disordersJoaquim Radua
Department of Psychological, Medicine, Institute of Psychiatry, King s College London, London SE5 8AF, England
Arch Gen Psychiatry 67:701-11. 2010..Whether obsessive-compulsive disorder (OCD) is adequately classified as an anxiety disorder is a matter of considerable debate... - Reliability and validity of the work and social adjustment scale in phobic disordersDavid Mataix-Cols
Institute of Psychiatry, King s College London, UK
Compr Psychiatry 46:223-8. 2005..The WSAS is a valid, reliable, and change-sensitive measure of work/social and other adjustment in phobic disorders, especially in agoraphobia and social phobia... - Obsessions and compulsions in children with Asperger's syndrome or high-functioning autism: a case-control studyHilary Mack
Maudsley Hospital, London, UK
Aust N Z J Psychiatry 44:1082-8. 2010..To compare the clinical characteristics and symptom severity of children with obsessive disorder (OCD) plus autism spectrum disorders (ASD) with those of children with OCD plus Tourette's syndrome (TS) or OCD alone... - Self-help with minimal therapist contact for obsessive-compulsive disorder: a reviewDavid Mataix-Cols
Institute of Psychiatry, King s College London, PO Box 69, De Crespigny Park, London SE5 8AF, UK
Eur Psychiatry 21:75-80. 2006..Their dissemination could save resources used by health care providers. We propose a stepped care model for the treatment of OCD... - Pragmatic evaluation of computer-aided self-help for anxiety and depressionIsaac M Marks
Department of Psychological Medicine, Charing Cross Campus, Imperial College School of Medicine, London, UK
Br J Psychiatry 183:57-65. 2003..Most anxiety/depression is not effectively treated. Aims Open evaluation of a free clinic giving immediate computer-aided cognitive-behavioural therapy (CBT) self-help plus brief advice from a therapist... - The Maudsley Obsessive-Compulsive Stimuli Set: validation of a standardized paradigm for symptom-specific provocation in obsessive-compulsive disorderDavid Mataix-Cols
Departments of Psychological Medicine and Psychology, King s College London, Institute of Psychiatry, United Kingdom
Psychiatry Res 168:238-41. 2009..The Maudsley Obsessive-Compulsive Stimuli Set has excellent convergent and discriminant validity, and it will be a useful resource for OCD researchers... - Neural responses to facial expressions of disgust but not fear are modulated by washing symptoms in OCDNatalia S Lawrence
Division of Psychological Medicine, Section of Neuroscience and Emotion, King s College London, London, United Kingdom
Biol Psychiatry 61:1072-80. 2007..This study explored neural systems underlying sensitivity to symptom-unrelated disgust and fear in OCD using functional neuroimaging... - Experiential avoidance and emotion regulation difficulties in hoarding disorderLorena Fernández de la Cruz
King s College London, Institute of Psychiatry, London, England, UK Electronic address
J Anxiety Disord 27:204-9. 2013..However, despite the lack of specificity, the findings raise some potentially useful clinical implications for the treatment of HD... - Screening people with anxiety/depression for suitability for guided self-helpLina Gega
School of Nursing and Midwifery, King s College, London, UK
Cogn Behav Ther 34:16-21. 2005..In conclusion, by quickly scanning the completed questionnaire, clinicians were able sensitively to detect patients' problem types that were suitable for certain forms of self-help. Some unsuitability items need refining... - Relation of neurological soft signs to nonverbal memory performance in obsessive-compulsive disorderDavid Mataix-Cols
Department of Psychological Medicine, GKT School of Medicine and Institute of Psychiatry, London, UK
J Clin Exp Neuropsychol 25:842-51. 2003..There might be at least two variables independently mediating nonverbal memory deficits in OCD: (1) a cognitive organization and planning component, and (2) a complex motor regulatory component... - Decision making and set shifting impairments are associated with distinct symptom dimensions in obsessive-compulsive disorderNatalia S Lawrence
Section of Neuroscience and Emotion, Division of Psychological Medicine and Psychiatry, Institute of Psychiatry, King s College London, London, England
Neuropsychology 20:409-19. 2006..These results help explain previous inconsistent findings in neuropsychological research in OCD and support recent neuroimaging data showing dissociable neural mechanisms involved in mediating the different OCD symptom dimensions... - Computer-aided self-exposure therapy for phobia/panic disorder: a pilot economic evaluationPaul McCrone
Centre for the Economics of Mental Health, Health Service and Population Research Department, Institute of Psychiatry, King s College London, De Crespigny Park, London, UK
Cogn Behav Ther 38:91-9. 2009..FF would be less cost-effective if face-to-face therapy was delivered by less qualified professionals. Caution is urged regarding these indicative findings given that these were secondary analyses... - Do patients with hoarding disorder have autistic traits?Alberto Pertusa
Department of Psychosis Studies, King s College London, Institute of Psychiatry, London, England, UK
Depress Anxiety 29:210-8. 2012..In order to further refine the diagnostic boundaries of HD, we examined the presence of autistic traits and theory of mind deficits in individuals with HD and of hoarding behavior in patients with ASD... - A multivariate twin study of obsessive-compulsive symptom dimensionsAlessandra C Iervolino
Department of Psychosis Studies, King s College London, London, England
Arch Gen Psychiatry 68:637-44. 2011..Obsessive-compulsive disorder (OCD) is clinically heterogeneous, but it is unclear whether this phenotypic heterogeneity reflects distinct, or partially distinct, etiologic mechanisms... - Structure of obsessive-compulsive symptoms in pediatric OCDDavid Mataix-Cols
King s College London, Institute of Psychiatry, Department of Psychological Medicine, P O Box 69, De Crespigny Park, UK
J Am Acad Child Adolesc Psychiatry 47:773-8. 2008..It is unclear whether the structure of obsessive-compulsive disorder (OCD) symptoms seen in adults is preserved in pediatric samples... - When hoarding is a symptom of OCD: a case series and implications for DSM-VAlberto Pertusa
Department of Psychosis Studies, King s College London, Institute of Psychiatry, London, England
Behav Res Ther 48:1012-20. 2010..We estimate that this clinical presentation is relatively rare and accounts for a minority of severe hoarding cases. We discuss the unique characteristics of hoarding as a symptom of OCD and the implications for DSM-V... - Evidence for a genetic overlap between body dysmorphic concerns and obsessive-compulsive symptoms in an adult female community twin sampleBenedetta Monzani
Institute of Psychiatry, Department of Psychosis Studies, King s College London, London, UK
Am J Med Genet B Neuropsychiatr Genet 159:376-82. 2012..These results support current recommendations to group BDD together with OCD in the same DSM-5 chapter, although comparison with other phenotypes such as somatoform disorders and social phobia is needed... - Obsessions and compulsions in the community: prevalence, interference, help-seeking, developmental stability, and co-occurring psychiatric conditionsMiguel A Fullana
King s College London, Institute of Psychiatry, UK
Am J Psychiatry 166:329-36. 2009..It is also unknown what variables predict help-seeking for these symptoms, whether they are developmentally stable, and whether they increase the risk of mental disorders... - Are there sex differences in neuropsychological functions among patients with obsessive-compulsive disorder?David Mataix-Cols
Department of Psychological Medicine, Institute of Psychiatry, King s College London, UK
Appl Neuropsychol 13:42-50. 2006..We conclude that sex does not seem to be a major determinant of neuropsychological function in OCD, but the observed cross-sex shifts on some tasks deserve further examination... - Voxel-wise meta-analysis of grey matter changes in obsessive-compulsive disorderJoaquim Radua
Division of Psychological Medicine, Institute of Psychiatry, PO 69, King s College London, London SE5 8AF
Br J Psychiatry 195:393-402. 2009..Whether the reported differences between participants with OCD and controls precede the onset of the symptoms and whether they are specific to OCD remains to be established... - Common and distinct neural correlates of obsessive-compulsive and related disordersDavid Mataix-Cols
Department of Psychological Medicine, King s College London, Institute of Psychiatry, London SE5 8AF, UK
Psychiatr Clin North Am 29:391-410, viii. 2006.... - Meta-analysis of gray matter abnormalities in autism spectrum disorder: should Asperger disorder be subsumed under a broader umbrella of autistic spectrum disorder?Esther Via
Department of Psychosis Studies, Institute of Psychiatry, King s College London, London, England
Arch Gen Psychiatry 68:409-18. 2011..It is unclear whether the current subtyping of ASD into autistic disorder and Asperger disorder is neurobiologically valid... - Declarative and procedural learning in individuals with subclinical obsessive-compulsive symptomsDavid Mataix-Cols
Division of Psychological Medicine, GKT School of Medicine and Institute of Psychiatry, London, UK
J Clin Exp Neuropsychol 25:830-41. 2003..These results replicate and expand upon previous findings and support a dimensional model of Obsessive-Compulsive Disorder... - Effect of referral source on outcome with cognitive-behavior therapy self-helpDavid Mataix-Cols
Department of Psychological Medicine, Imperial College London, W6 8RP London, UK
Compr Psychiatry 47:241-5. 2006..We conclude that GP referrals had the best outcome with CCBT for anxiety/depressive disorders. Referral source can be important in psychotherapy research because it may affect the type of patient seen and may predict treatment outcome... - Convergent and discriminant validity of the Yale-Brown Obsessive-Compulsive Scale Symptom ChecklistDavid Mataix-Cols
Division of Psychological Medicine, GKT School of Medicine and Institute of Psychiatry, London, UK
Psychother Psychosom 73:190-6. 2004..The factor structure of the Yale-Brown Obsessive-Compulsive Scale Symptom Checklist (Y-BOCS-SC) has been well established, but its convergent and divergent reliability have yet to be studied... - Probing the working memory system in chronic fatigue syndrome: a functional magnetic resonance imaging study using the n-back taskXavier Caseras
Unitat de Psicologia Mèdica, Institut de Neurociencies, Universitat Autonoma de Barcelona, Barcelona, Spain
Psychosom Med 68:947-55. 2006..However, objective evidence supporting these claims is inconsistent. The present functional magnetic resonance imaging study examined the neural correlates of working memory in patients with CFS compared with controls... - Neural correlates of anxiety associated with obsessive-compulsive symptom dimensions in normal volunteersDavid Mataix-Cols
Division of Psychological Medicine, GKT School of Medicine and Institute of Psychiatry, London, United Kingdom
Biol Psychiatry 53:482-93. 2003..Further investigation of the neural basis of OCD symptom dimensions is required... - Spanish adaptation of the Dimensional Yale-Brown Obsessive-Compulsive ScaleAlberto Pertusa
Obsessive Compulsive Disorder Clinical and Research Unit, Department of Psychiatry, Bellvitge Hospital, Barcelona, Spain
Compr Psychiatry 51:641-8. 2010..The goal of this study was to further explore the psychometric properties of the DY-BOCS in a Spanish sample... - Is the use of the wooden and computerized versions of the Tower of Hanoi puzzle equivalent?David Mataix-Cols
Department of Psychiatry, Imperial College School of Medicine, London, England
Appl Neuropsychol 9:117-20. 2002..It remains to be tested whether age and computer experience affect performance differentially on the computerized and the wooden versions of the TH puzzle and whether these results are replicated in brain-damaged patients... - Finders keepers: the features differentiating hoarding disorder from normative collectingAshley E Nordsletten
King s College London, Institute of Psychiatry, London, UK
Compr Psychiatry 54:229-37. 2013..Collectors constitute a valid population within which to test the diagnostic boundaries of HD. The current study explored the features that differentiate pathological hoarding from normative collecting... - Temper outbursts in paediatric obsessive-compulsive disorder and their association with depressed mood and treatment outcomeGeorgina Krebs
OCD Clinic for Young People, South London and Maudsley NHS Foundation Trust, London, UK
J Child Psychol Psychiatry 54:313-22. 2013.... - The use of a nonimmersive virtual reality programme in anorexia nervosa: a single case-reportValentina Cardi
Department of Psychological Medicine, Section of Eating Disorders, Institute of Psychiatry, King s College London, UK
Eur Eat Disord Rev 20:240-5. 2012..The aim of this case report was to describe the use of a virtual reality (VR) programme developed to facilitate exposure to food as a supplement to treatment for a person with AN... - Sex differences in neural responses to disgusting visual stimuli: implications for disgust-related psychiatric disordersXavier Caseras
Department of Psychological Medicine, King s College London, Institute of Psychiatry, United Kingdom
Biol Psychiatry 62:464-71. 2007..The aim of this functional magnetic resonance imaging (fMRI) study was to examine possible sex differences in neural responses to disgust-inducing stimuli that might help explain this female predominance... - Gray matter volume abnormalities in ADHD: voxel-based meta-analysis exploring the effects of age and stimulant medicationTomohiro Nakao
Institute of Psychiatry, King s College London, UK
Am J Psychiatry 168:1154-63. 2011..The authors conducted a meta-analysis of voxel-based morphometry studies in children and adults with ADHD and examined the potential effects of age and stimulant medication on regional gray matter volumes... - Photograph-aided assessment of clutter in hoarding disorder: is a picture worth a thousand words?Lorena Fernández de la Cruz
Intitute of Psychiatry, King s College London, De Crespigny Park, London, United Kingdom
Depress Anxiety 30:61-6. 2013..The assessment of clutter ideally requires home visits, although such assessments are sometimes not feasible. This study examined whether photographs from patients' homes can assist in the diagnostic process... - Meta-analysis of fMRI studies of timing in attention-deficit hyperactivity disorder (ADHD)Heledd Hart
Department of Child and Adolescent Psychiatry, Institute of Psychiatry, King s College London, London, UK
Neurosci Biobehav Rev 36:2248-56. 2012.... - Symptom stability in adult obsessive-compulsive disorder: data from a naturalistic two-year follow-up studyDavid Mataix-Cols
Department of Psychiatry, Imperial College School of Medicine, London, UK
Am J Psychiatry 159:263-8. 2002..This study systematically investigated the temporal stability of individual symptoms and symptom dimensions of OCD in adult patients who were followed prospectively for 2 years... - Obsessions and compulsions in Asperger syndrome and high-functioning autismAilsa J Russell
Department of Psychology, Institute of Psychiatry, King s College, London, UK
Br J Psychiatry 186:525-8. 2005..Obsessive-compulsive behaviours are common and disabling in autistic-spectrum disorders (ASD) but little is known about how they compare with those experienced by people with obsessive-compulsive disorder (OCD)... - Deconstructing obsessive-compulsive disorder: a multidimensional perspectiveDavid Mataix-Cols
Departments of Psychological Medicine and Psychology, Institute of Psychiatry, King s College London, London, UK
Curr Opin Psychiatry 19:84-9. 2006..e. age of onset, presence of comorbid tics, positive family history) and symptom theme, with particular emphasis on the latter... - A multidimensional model of obsessive-compulsive disorderDavid Mataix-Cols
Institute of Psychiatry, London
Am J Psychiatry 162:228-38. 2005..The need for a dimensional rating scale and suggestions for future research aimed at reducing the burden of this disorder are discussed... - Prevalence and heritability of compulsive hoarding: a twin studyAlessandra C Iervolino
Department of Psychology, King s College London, Institute of Psychiatry, London SE5 8AF, UK
Am J Psychiatry 166:1156-61. 2009..It appears to be highly prevalent and to run in families. However, this familiality could be due to genetic or environmental factors. This study examined the prevalence and heritability of compulsive hoarding in a large sample of twins... - Hoarding versus collecting: where does pathology diverge from play?Ashley E Nordsletten
Department of Psychosis Studies, King s College London, Institute of Psychiatry, London, UK
Clin Psychol Rev 32:165-76. 2012..For a minority of 'extreme' collectors, a diagnosis may potentially be adequate. This review highlights the similarities and differences between hoarding and collecting and offers suggestions for further research in this group... - Prevalence of anti-basal ganglia antibodies in adult obsessive-compulsive disorder: cross-sectional studyTimothy R J Nicholson
National Institute of Health Research Specialist Biomedical Research Centre for Mental Health at South London and Maudsley NHS Foundation Trust and The Institute of Psychiatry, King s College London, London
Br J Psychiatry 200:381-6. 2012..It is proposed that antibodies raised against streptococcal proteins cross-react with neuronal proteins (antigens) in the brain, particularly in the basal ganglia, which is a brain region implicated in OCD pathogenesis... 
Meta-analytic methods for neuroimaging data explainedJoaquim Radua
Institute of Psychiatry, King s College London, De Crespigny Park, London, UK
Biol Mood Anxiety Disord 2:6. 2012....- Internet-guided self-help with or without exposure therapy for phobic and panic disordersAndreas J Schneider
Department of Psychological Medicine, Imperial College London and Institute of Psychiatry, King's College London, London, UK
Psychother Psychosom 74:154-64. 2005..Analysis is needed of how non-exposure CBT produced its shorter-term effect... - Brief scheduled phone support from a clinician to enhance computer-aided self-help for obsessive-compulsive disorder: randomized controlled trialMark Kenwright
Institute of Psychiatry, Kings College London and South London and Maudsley Mental Health Trust, London, UK
J Clin Psychol 61:1499-508. 2005..Giving brief support proactively by phone enhanced OCD patients' completion of and improvement with computer-aided self-help... - Applications of functional magnetic resonance imaging in psychiatryMartina T Mitterschiffthaler
Centre for Neuroimaging Sciences, Department of Clinical Neuroscience, Institute of Psychiatry, King's College London, London, UK
J Magn Reson Imaging 23:851-61. 2006..The role of fMRI in the objective assessment of therapeutic intervention and early prediction of response to treatment is also discussed...