Research Topics
| Arduino A MangoniSummaryAffiliation: King's College London Country: UK Publications
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Detail Information
Publications
Folic acid enhances endothelial function and reduces blood pressure in smokers: a randomized controlled trialA A Mangoni
Department of Health Care of the Elderly, Guy s, King s, and St Thomas School of Medicine, King s College London, UK
J Intern Med 252:497-503. 2002..We sought to determine whether folic acid supplementation, by reducing plasma homocysteine concentrations, enhanced endothelial function and reduced arterial stiffness in smokers...
Impact of age on QT interval and QT dispersion in healthy subjects: a regression analysisArduino A Mangoni
Department of Health Care of the Elderly, Guy s, King s, and St Thomas School of Medicine, King s College London, UK
Age Ageing 32:326-31. 2003..We studied the effects of age, gender, body mass index, smoking status, and blood pressure on these electrocardiographic parameters...
Paradoxical vasodilation during lower body negative pressure in patients with vasodepressor carotid sinus syndromeArduino A Mangoni
Department of Health Care of the Elderly, Guy s, King s, and St Thomas School of Medicine, King s College, London, United Kingdom
J Am Geriatr Soc 51:853-7. 2003....
Effects of folic acid supplementation on inflammatory and thrombogenic markers in chronic smokers. A randomised controlled trialArduino A Mangoni
Department of Health Care of the Elderly, Guy s, King s, and St Thomas School of Medicine, King s College Hospital Dulwich, East Dulwich Grove, London SE22 8PT, UK
Thromb Res 110:13-7. 2003..We investigated whether lowering homocysteine by folic acid supplementation might reduce the plasma concentration of inflammatory and thrombogenic markers in chronic smokers...
Age-related changes in pharmacokinetics and pharmacodynamics: basic principles and practical applicationsA A Mangoni
Department of Health Care of the Elderly, Guy s, King s, and St Thomas School of Medicine, King s College London, London
Br J Clin Pharmacol 57:6-14. 2004..This review focuses on the main age-related physiological changes affecting different organ systems and their implications for pharmacokinetics and pharmacodynamics of drugs...
Effects of folic acid supplementation on psychomotor performance and hemorheology in healthy elderly subjectsRohan Pathansali
Department of Health Care of the Elderly, Guy's, King's and St Thomas' School of Medicine, King's College London, London SE5 9PJ, UK
Arch Gerontol Geriatr 43:127-37. 2006..Short-term folic acid supplementation does not enhance psychomotor performance or reduce blood viscosity in healthy elderly subjects with normal serum folic acid levels and preserved cognitive function...
Off-label prescribing in older patientsStephen H D Jackson
Department of Clinical Gerontology, Kings Health Partners Academic Health Science Centre, London, UK
Drugs Aging 29:427-34. 2012..This article discusses the current epidemiology and trends in off-label prescribing in older patients, the scientific and ethical justification of this practice, medico-legal implications, and proposed strategies for risk mitigation...
Homocysteine and cardiovascular disease: current evidence and future prospectsArduino A Mangoni
Department of Health Care of the Elderly, Guy's, King's, and St. Thomas' School of Medicine, King's College, London, United Kingdom
Am J Med 112:556-65. 2002....
Determinants of failure to prescribe target doses of angiotensin-converting enzyme inhibitors for heart failureJuliet Manyemba
Department of Health Care of the Elderly, Clinical Age Research Unit, Guy's King's and St. Thomas School of Medicine, King's College Hospital, London SE5 9PJ, UK
Eur J Heart Fail 5:693-6. 2003
Short-term oral folic acid supplementation enhances endothelial function in patients with type 2 diabetesArduino A Mangoni
Department of Clinical Pharmacology, Centre for Neuroscience, Flinders University, School of Medicine, Adelaide, Australia
Am J Hypertens 18:220-6. 2005..We sought to determine whether oral folic acid supplementation, by lowering homocysteine levels, enhanced endothelial function and reduced arterial stiffness in type 2 diabetes...
Folic acid, inflammation, and atherosclerosis: false hopes or the need for better trials?Arduino A Mangoni
Department of Clinical Pharmacology and Centre for Neuroscience, School of Medicine, Flinders University, GPO Box 2100, Adelaide 5001, Australia
Clin Chim Acta 367:11-9. 2006....
Folic acid: a marker of endothelial function in type 2 diabetes?Arduino A Mangoni
Department of Clinical Pharmacology, Centre for Neuroscience, School of Medicine, Flinders University, Adelaide, SA, Australia
Vasc Health Risk Manag 1:79-83. 2005..Therefore, folic acid might represent a novel "biomarker" of endothelial function. We sought to determine whether plasma levels of folic acid determine endothelial-dependent vasodilation in patients with type 2 diabetes...
Lack of significant effects of methionine loading on endothelial function in elderly volunteersSimon R Hart
Division of Clinical Neuroscience, University of Edinburgh, Western General Hospital, Edinburgh, Scotland EH4 2XU, United Kingdom
Heart Lung Circ 15:358-61. 2006....
High-resolution transthoracic echocardiography of the left anterior descending coronary artery: a novel noninvasive assessment of coronary vasoreactivityRebecca Perry
Cardiac Services, Flinders Medical Centre, Flinders University, Bedford Park, South Australia, Australia
J Am Soc Echocardiogr 21:134-8. 2008....
The impact of advancing age on P-glycoprotein expression and activity: current knowledge and future directionsArduino A Mangoni
Expert Opin Drug Metab Toxicol 3:315-20. 2007..This review discusses the current knowledge about the effects of advancing age on P-glycoprotein expression and activity. A critical appraisal of the published literature and an overview on future research directions are also provided...
Influence of comorbidities and medication use on tilt table test outcome in elderly patientsBiju Paul
Department of Clinical Pharmacology, School of Medicine, Flinders University and Flinders Medical Centre, Adelaide, Australia
Pacing Clin Electrophysiol 30:540-3. 2007..However, preexisting comorbidities and medications affecting hemodynamic response might affect TTT outcome (i.e. presence or absence of vasomotor syncope). We studied the influence of these compounding factors on TTT outcome...
An early drop in systolic blood pressure predicts a positive tilt table test in elderly patients with unexplained falls or syncopeDerek Yiu
Department of Clinical Pharmacology, Flinders Medical Centre, Bedford Park, South Australia 5042, Australia
Age Ageing 35:183-5. 2006
Outcome following mitral valve replacement in patients with mitral stenosis and moderately reduced left ventricular ejection fractionArduino A Mangoni
Department of Medicine, Cardiology Division, Massachusetts General Hospital, Boston, MA 02114-3117, USA
Eur J Cardiothorac Surg 22:90-4. 2002..Moderate depression of LV EF should not be a contraindication to MVR for MS...
Cardiovascular drug therapy in elderly patients: specific age-related pharmacokinetic, pharmacodynamic and therapeutic considerationsArduino A Mangoni
Department of Clinical Pharmacology, School of Medicine, Flinders University, Adelaide, South Australia, Australia
Drugs Aging 22:913-41. 2005..In particular, there is very little information on patients >80 years of age, thus raising important concerns about the correct use of these drugs in this constantly growing population...
Acute hypotensive effects of oral cisapride and erythromycin in healthy subjectsArduino A Mangoni
Br J Clin Pharmacol 58:223-4. 2004
Diastolic and pulse pressure: the old and the new?Arduino A Mangoni
Hypertension 43:531-2. 2004
