William D C Man

Summary

Affiliation: King's College London
Country: UK

Publications

  1. ncbi request reprint Postprandial effects on twitch transdiaphragmatic pressure
    W D C Man
    Dept of Respiratory Medicine and Allergy, Guy s, King s and St Thomas School of Medicine, London, UK
    Eur Respir J 20:577-80. 2002
  2. ncbi request reprint Symptoms and quadriceps fatigability after walking and cycling in chronic obstructive pulmonary disease
    William D C Man
    Respiratory Muscle Laboratory, Guy s King s and St Thomas School of Medicine, King s College Hospital, Bessemer Road, London SE5 9PJ UK
    Am J Respir Crit Care Med 168:562-7. 2003
  3. ncbi request reprint Cough gastric pressure and maximum expiratory mouth pressure in humans
    William D C Man
    Respiratory Muscle Laboratory, Guy s King s and St Thomas School of Medicine, King s College Hospital, London, UK
    Am J Respir Crit Care Med 168:714-7. 2003
  4. pmc Non-volitional assessment of skeletal muscle strength in patients with chronic obstructive pulmonary disease
    W D C Man
    Respiratory Muscle Laboratory, Guy s, King s and St Thomas School of Medicine, King s College Hospital, London, UK
    Thorax 58:665-9. 2003
  5. pmc Effect of salmeterol on respiratory muscle activity during exercise in poorly reversible COPD
    W D C Man
    Respiratory Muscle Laboratory, Guy s, King s and St Thomas School of Medicine, King s College Hospital, London, UK
    Thorax 59:471-6. 2004
  6. pmc Community pulmonary rehabilitation after hospitalisation for acute exacerbations of chronic obstructive pulmonary disease: randomised controlled study
    William D C Man
    Respiratory Muscle Laboratory, Guy s, King s, and St Thomas School of Medicine, King s College Hospital, London SE5 9PJ
    BMJ 329:1209. 2004
  7. pmc Abdominal muscle and quadriceps strength in chronic obstructive pulmonary disease
    W D C Man
    Respiratory Muscle Laboratory, Guy s, King s and St Thomas School of Medicine, King s College Hospital, Bessemer Road, London SE5 9PJ, UK
    Thorax 60:718-22. 2005
  8. doi request reprint Reliability and validity of 4-metre gait speed in COPD
    Samantha S C Kon
    Royal Brompton and Harefield NHS Foundation Trust and Imperial College, London, UK
    Eur Respir J 42:333-40. 2013
  9. ncbi request reprint Minimum clinically important difference for the COPD Assessment Test: a prospective analysis
    Samantha S C Kon
    NIHR Respiratory Biomedical Research Unit, Royal Brompton and Harefield NHS Foundation Trust, London, UK Imperial College, London, UK Electronic address
    Lancet Respir Med 2:195-203. 2014
  10. ncbi request reprint Angiotensin converting enzyme genotype and strength in chronic obstructive pulmonary disease
    Nicholas S Hopkinson
    Respiratory Muscle Laboratory, Royal Brompton Hospital, Fulham Road, London, SW3 6NP, United Kingdom
    Am J Respir Crit Care Med 170:395-9. 2004

Collaborators

Detail Information

Publications20

  1. ncbi request reprint Postprandial effects on twitch transdiaphragmatic pressure
    W D C Man
    Dept of Respiratory Medicine and Allergy, Guy s, King s and St Thomas School of Medicine, London, UK
    Eur Respir J 20:577-80. 2002
    ....
  2. ncbi request reprint Symptoms and quadriceps fatigability after walking and cycling in chronic obstructive pulmonary disease
    William D C Man
    Respiratory Muscle Laboratory, Guy s King s and St Thomas School of Medicine, King s College Hospital, Bessemer Road, London SE5 9PJ UK
    Am J Respir Crit Care Med 168:562-7. 2003
    ..01; potentiated p = 0.003). Leg effort is an infrequent symptom after walking in COPD, and low frequency fatigue of the quadriceps is an infrequent feature of incremental walking...
  3. ncbi request reprint Cough gastric pressure and maximum expiratory mouth pressure in humans
    William D C Man
    Respiratory Muscle Laboratory, Guy s King s and St Thomas School of Medicine, King s College Hospital, London, UK
    Am J Respir Crit Care Med 168:714-7. 2003
    ..Low maximal expiratory mouth pressures do not always indicate expiratory muscle weakness. Cough gastric pressure provides a useful complementary test for the assessment of expiratory muscle strength...
  4. pmc Non-volitional assessment of skeletal muscle strength in patients with chronic obstructive pulmonary disease
    W D C Man
    Respiratory Muscle Laboratory, Guy s, King s and St Thomas School of Medicine, King s College Hospital, London, UK
    Thorax 58:665-9. 2003
    ..Conversely, if deconditioning and disuse are the principal aetiological factors, weakness would be most marked in the lower limb muscles...
  5. pmc Effect of salmeterol on respiratory muscle activity during exercise in poorly reversible COPD
    W D C Man
    Respiratory Muscle Laboratory, Guy s, King s and St Thomas School of Medicine, King s College Hospital, London, UK
    Thorax 59:471-6. 2004
    ..We hypothesised that long acting bronchodilators improve symptoms by reducing dynamic hyperinflation and work of breathing, as measured by respiratory muscle pressure-time products...
  6. pmc Community pulmonary rehabilitation after hospitalisation for acute exacerbations of chronic obstructive pulmonary disease: randomised controlled study
    William D C Man
    Respiratory Muscle Laboratory, Guy s, King s, and St Thomas School of Medicine, King s College Hospital, London SE5 9PJ
    BMJ 329:1209. 2004
    ..To evaluate the effects of an early community based pulmonary rehabilitation programme after hospitalisation for acute exacerbations of chronic obstructive pulmonary disease (COPD)...
  7. pmc Abdominal muscle and quadriceps strength in chronic obstructive pulmonary disease
    W D C Man
    Respiratory Muscle Laboratory, Guy s, King s and St Thomas School of Medicine, King s College Hospital, Bessemer Road, London SE5 9PJ, UK
    Thorax 60:718-22. 2005
    ..A study was undertaken to test the hypothesis that more severe weakness exists in the quadriceps than in the abdominal muscles of patients with COPD compared with healthy elderly controls...
  8. doi request reprint Reliability and validity of 4-metre gait speed in COPD
    Samantha S C Kon
    Royal Brompton and Harefield NHS Foundation Trust and Imperial College, London, UK
    Eur Respir J 42:333-40. 2013
    ..The 4MGS is reliable in COPD, correlates with exercise capacity, dyspnoea and health-related quality of life, and has potential as a simple assessment tool in COPD. ..
  9. ncbi request reprint Minimum clinically important difference for the COPD Assessment Test: a prospective analysis
    Samantha S C Kon
    NIHR Respiratory Biomedical Research Unit, Royal Brompton and Harefield NHS Foundation Trust, London, UK Imperial College, London, UK Electronic address
    Lancet Respir Med 2:195-203. 2014
    ..However, the minimum clinically important difference (MCID) has not been established. We aimed to identify the MCID for the CAT using anchor-based and distribution-based methods...
  10. ncbi request reprint Angiotensin converting enzyme genotype and strength in chronic obstructive pulmonary disease
    Nicholas S Hopkinson
    Respiratory Muscle Laboratory, Royal Brompton Hospital, Fulham Road, London, SW3 6NP, United Kingdom
    Am J Respir Crit Care Med 170:395-9. 2004
    ..In chronic obstructive pulmonary disease the deletion allele is associated with greater quadriceps strength independent of confounding factors...
  11. doi request reprint Pulmonary rehabilitation and acute exacerbations of COPD
    Samantha S C Kon
    Respiratory Biomedical Research Unit, Royal Brompton and Harefield NHS Foundation Trust and Imperial College, Hill End Road, Harefield, London, UK
    Expert Rev Respir Med 6:523-31; quiz 531. 2012
    ..This article reviews the role of pulmonary rehabilitation in the prevention and treatment of acute exacerbations of COPD...
  12. doi request reprint Outpatient pulmonary rehabilitation following acute exacerbations of COPD
    John M Seymour
    Department of Respiratory Medicine, King s College Hospital, London SE5 9RJ, UK
    Thorax 65:423-8. 2010
    ..28, 95% CI 0.10 to 0.82, p=0.02). CONCLUSIONS Post-exacerbation rehabilitation in COPD can reduce re-exacerbation events that require admission or hospital attendance over a 3-month period. Clinical Trials Registration Number NCT00557115...
  13. pmc Increased skeletal muscle-specific microRNA in the blood of patients with COPD
    Anna Donaldson
    Section of Molecular Medicine, National Heart and Lung Institute, Imperial College London, London, UK
    Thorax 68:1140-9. 2013
    ..To determine whether plasma myomiR levels were associated with fibre size or fibre proportion, we measured myomiRs in plasma from patients with COPD and healthy controls...
  14. doi request reprint Heterogeneity of quadriceps muscle phenotype in chronic obstructive pulmonary disease (Copd); implications for stratified medicine?
    Samantha A Natanek
    NIHR Respiratory Biomedical Research Unit of the Royal Brompton, and Harefield NHS Foundation Trust and Imperial College London, London, SW3 6NP, United Kingdom Department of Respiratory Medicine, NUTRIM School for Nutrition, Toxicology and Metabolism, Maastricht University Medical Centre, AZ Maastricht, Netherlands Molecular Medicine Section, National Heart and Lung Institute, Imperial College London, South Kensington Campus, London, United Kingdom
    Muscle Nerve 48:488-97. 2013
    ..Quadriceps muscle dysfunction is common in COPD. Determining, and, if possible, predicting quadriceps phenotype in COPD is important for patient stratification for therapeutic trials...
  15. pmc Quadriceps strength predicts mortality in patients with moderate to severe chronic obstructive pulmonary disease
    Elisabeth B Swallow
    Respiratory Muscle Laboratory, Royal Brompton Hospital, Fulham Road, London SW3 6NP, UK
    Thorax 62:115-20. 2007
    ..Prognosis in chronic obstructive pulmonary disease (COPD) is poorly predicted by indices of air flow obstruction, because other factors that reflect the systemic nature of the disease also influence prognosis...
  16. doi request reprint Skeletal muscle dysfunction in COPD: clinical and laboratory observations
    William D C Man
    Royal Brompton and Harefield NHS Trust, London, UK
    Clin Sci (Lond) 117:251-64. 2009
    ..Increasing knowledge of the molecular pathways of muscle wasting will lead to the development of new therapeutic agents and strategies to combat COPD muscle dysfunction...
  17. doi request reprint Denoising of diaphragmatic electromyogram signals for respiratory control and diagnostic purposes
    Stephen R Alty
    King s College London, Division of Engineering, London WC2R2LS, UK
    Conf Proc IEEE Eng Med Biol Soc 2008:5560-3. 2008
    ..These signals have two applications, firstly in artificial ventilator systems and as a diagnostic tool for health professionals...
  18. pmc Singing classes for chronic obstructive pulmonary disease: a randomized controlled trial
    Victoria M Lord
    NIHR Respiratory Biomedical Research Unit at Royal Brompton and Harefield NHS Foundation Trust and Imperial College, London, UK
    BMC Pulm Med 12:69. 2012
    ..It is not clear how much of this benefit is specific to singing and how much relates to the classes being a group activity that addresses social isolation...
  19. doi request reprint The COPD assessment test (CAT): response to pulmonary rehabilitation. A multicentre, prospective study
    James W Dodd
    St George s Hospital NHS Trust, London, UK
    Thorax 66:425-9. 2011
    ..It is not known how the CAT score performs in the context of clinical pulmonary rehabilitation (PR) programmes or what the minimum clinically important difference is...
  20. doi request reprint Stanford Seven-Day Physical Activity Recall questionnaire in COPD
    Benjamin E Garfield
    NIHR Respiratory Biomedical Research Unit, Royal Brompton and Harefield NHS Foundation Trust, London, UK
    Eur Respir J 40:356-62. 2012
    ....