Affiliation: King's College London
- Oxytocin receptor genotype modulates ventral striatal activity to social cues and response to stressful life eventsEva Loth
Institute of Psychiatry, King s College London MRC Social, Genetic and Developmental Psychiatry Centre, London Electronic address
Biol Psychiatry 76:367-76. 2014..This study aimed to comprehensively investigate OXTR-dependent brain mechanisms associated with social-affective problems...
- When seeing depends on knowing: adults with Autism Spectrum Conditions show diminished top-down processes in the visual perception of degraded faces but not degraded objectsEva Loth
MRC Social, Genetic, and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, De Crespigny Park, London SE5 8AF, United Kingdom
Neuropsychologia 48:1227-36. 2010..Implications for future work on the underlying mechanisms, at the cognitive and neurofunctional levels, are discussed...
- Variety is not the spice of life for people with autism spectrum disorders: frequency ratings of central, variable and inappropriate aspects of common real-life eventsEva Loth
MRC Social, Genetic, and Developmental Psychiatry Centre, Institute of Psychiatry, King s College, De Crespigny Park, London SE5 8AF, UK
J Autism Dev Disord 40:730-42. 2010..Implications for the understanding of some repetitive behaviours, such as the tendency to adhere to inflexible routines, are discussed...
- Do high-functioning people with autism spectrum disorder spontaneously use event knowledge to selectively attend to and remember context-relevant aspects in scenes?Eva Loth
MRC Social, Genetic, and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, De Crespigny Park, Denmark Hill, London SE5 8AF, UK
J Autism Dev Disord 41:945-61. 2011..Gaze-tracking suggests that one factor in these memory differences may be diminished top-down effects of event schemas on initial attention (first ten fixations) to relevant items in ASD...
- Neural mechanisms of attention-deficit/hyperactivity disorder symptoms are stratified by MAOA genotypeCharlotte Nymberg
Medical Research Council Social, Genetic and Developmental Psychiatry Centre CN, TJ, SL, BR, SD, GB, AC, PC, El, gs, Institute of Psychiatry, King s College London, London, United Kingdom Electronic address
Biol Psychiatry 74:607-14. 2013..The relative contribution of these frontostriatal mechanisms to ADHD symptoms and their genetic determinants is largely unexplored...
- Sex differences in COMT polymorphism effects on prefrontal inhibitory control in adolescenceThomas P White
Department of Psychosis Studies, Institute of Psychiatry, King s College London, London, UK
Neuropsychopharmacology 39:2560-9. 2014..These sexually dimorphic effects of COMT on inhibitory brain activation have important implications for our understanding of the contrasting patterns of prefrontally governed psychopathology observed in males and females. ..
- RASGRF2 regulates alcohol-induced reinforcement by influencing mesolimbic dopamine neuron activity and dopamine releaseDavid Stacey
Institute of Psychiatry, King s College, London SE5 8AF, United Kingdom
Proc Natl Acad Sci U S A 109:21128-33. 2012..Together, these combined animal and human data indicate a role for RASGRF2 in the regulation of mesolimbic dopamine neuron activity, reward response, and alcohol use and abuse...