Kristin R Laurens

Summary

Affiliation: King's College London
Country: UK

Publications

  1. ncbi request reprint Community screening for psychotic-like experiences and other putative antecedents of schizophrenia in children aged 9-12 years
    Kristin R Laurens
    Department of Forensic Mental Health Science, Institute of Psychiatry, King s College London, Box P023, De Crespigny Park, London SE5 8AF, UK
    Schizophr Res 90:130-46. 2007
  2. ncbi request reprint Attention orienting dysfunction during salient novel stimulus processing in schizophrenia
    Kristin R Laurens
    Department of Forensic Mental Health Science, Institute of Psychiatry, King s College London, University of London, Box P023, De Crespigny Park, London SE5 8AF, UK
    Schizophr Res 75:159-71. 2005
  3. doi request reprint Amygdala hypoactivity to fearful faces in boys with conduct problems and callous-unemotional traits
    Alice P Jones
    Medical Research Council s Social, Genetic, and Developmental Psychiatry Centre, Department of Forensic Mental Health, Institute of Psychiatry, King s College London, UK
    Am J Psychiatry 166:95-102. 2009
  4. doi request reprint Error-related processing dysfunction in children aged 9 to 12 years presenting putative antecedents of schizophrenia
    Kristin R Laurens
    Department of Forensic Mental Health Science, Institute of Psychiatry, King s College London, London SE5 8AF, United Kingdom
    Biol Psychiatry 67:238-45. 2010
  5. ncbi request reprint Neurocognitive performance in children aged 9-12 years who present putative antecedents of schizophrenia
    Alexis E Cullen
    King s College London, Department of Forensic and Neurodevelopmental Sciences Box P023, Institute of Psychiatry, De Crespigny Park, London SE5 8AF, United Kingdom
    Schizophr Res 121:15-23. 2010
  6. pmc Temporal lobe volume abnormalities precede the prodrome: a study of children presenting antecedents of schizophrenia
    Alexis E Cullen
    To whom correspondence should be addressed Department of Forensic and Neurodevelopmental Sciences, Institute of Psychiatry, Box P023, De Crespigny Park, London, SE5 8AF tel 44 20 7848 5678, fax 44 0 20 7848 0754, E mail
    Schizophr Bull 39:1318-27. 2013
  7. ncbi request reprint Cortisol awakening response and diurnal cortisol among children at elevated risk for schizophrenia: Relationship to psychosocial stress and cognition
    Alexis E Cullen
    Department of Forensic and Neurodevelopmental Sciences Box P023, Institute of Psychiatry, De Crespigny Park, London SE5 8AF, United Kingdom Electronic address
    Psychoneuroendocrinology 46:1-13. 2014
  8. doi request reprint Persisting psychotic-like experiences are associated with both externalising and internalising psychopathology in a longitudinal general population child cohort
    Johnny M Downs
    Department of Forensic and Neurodevelopmental Sciences, Institute of Psychiatry, King s College London, London, United Kingdom
    Schizophr Res 144:99-104. 2013
  9. doi request reprint Size matters: increased grey matter in boys with conduct problems and callous-unemotional traits
    Stephane A De Brito
    Department of Forensic Mental Health Science, Institute of Psychiatry, King s College, London, UK
    Brain 132:843-52. 2009
  10. doi request reprint Cognitive impairment among children at-risk for schizophrenia
    Hannah Dickson
    Department of Forensic and Neurodevelopmental Sciences, Institute of Psychiatry, King s College London, United Kingdom Electronic address
    J Psychiatr Res 50:92-9. 2014

Detail Information

Publications18

  1. ncbi request reprint Community screening for psychotic-like experiences and other putative antecedents of schizophrenia in children aged 9-12 years
    Kristin R Laurens
    Department of Forensic Mental Health Science, Institute of Psychiatry, King s College London, Box P023, De Crespigny Park, London SE5 8AF, UK
    Schizophr Res 90:130-46. 2007
    ..The results suggest that questionnaire screening of community samples of children for the putative antecedents of schizophrenia spectrum disorders is feasible. Accuracy of identification will only be established by follow-up studies...
  2. ncbi request reprint Attention orienting dysfunction during salient novel stimulus processing in schizophrenia
    Kristin R Laurens
    Department of Forensic Mental Health Science, Institute of Psychiatry, King s College London, University of London, Box P023, De Crespigny Park, London SE5 8AF, UK
    Schizophr Res 75:159-71. 2005
    ..In addition, trend results suggest that patients experienced increased distraction by novel stimuli...
  3. doi request reprint Amygdala hypoactivity to fearful faces in boys with conduct problems and callous-unemotional traits
    Alice P Jones
    Medical Research Council s Social, Genetic, and Developmental Psychiatry Centre, Department of Forensic Mental Health, Institute of Psychiatry, King s College London, UK
    Am J Psychiatry 166:95-102. 2009
    ..Using functional MRI, the authors evaluated differences in neural response to emotional stimuli between boys with conduct problems and elevated levels of callous-unemotional traits and comparison boys...
  4. doi request reprint Error-related processing dysfunction in children aged 9 to 12 years presenting putative antecedents of schizophrenia
    Kristin R Laurens
    Department of Forensic Mental Health Science, Institute of Psychiatry, King s College London, London SE5 8AF, United Kingdom
    Biol Psychiatry 67:238-45. 2010
    ..This study examined whether ASz children display brain function abnormalities during error processing that are similar to those exhibited by adults with schizophrenia...
  5. ncbi request reprint Neurocognitive performance in children aged 9-12 years who present putative antecedents of schizophrenia
    Alexis E Cullen
    King s College London, Department of Forensic and Neurodevelopmental Sciences Box P023, Institute of Psychiatry, De Crespigny Park, London SE5 8AF, United Kingdom
    Schizophr Res 121:15-23. 2010
    ..The present study aimed to determine whether ASz children also present neurocognitive deficits that are commonly observed in patients with schizophrenia...
  6. pmc Temporal lobe volume abnormalities precede the prodrome: a study of children presenting antecedents of schizophrenia
    Alexis E Cullen
    To whom correspondence should be addressed Department of Forensic and Neurodevelopmental Sciences, Institute of Psychiatry, Box P023, De Crespigny Park, London, SE5 8AF tel 44 20 7848 5678, fax 44 0 20 7848 0754, E mail
    Schizophr Bull 39:1318-27. 2013
    ..Prospective studies following the brain development of at-risk children are needed. ..
  7. ncbi request reprint Cortisol awakening response and diurnal cortisol among children at elevated risk for schizophrenia: Relationship to psychosocial stress and cognition
    Alexis E Cullen
    Department of Forensic and Neurodevelopmental Sciences Box P023, Institute of Psychiatry, De Crespigny Park, London SE5 8AF, United Kingdom Electronic address
    Psychoneuroendocrinology 46:1-13. 2014
    ..We speculate that the blunted CAR may constitute an early (potentially genetically mediated) marker of psychosis vulnerability, whilst elevated diurnal cortisol levels may emerge only proximally to disease onset. ..
  8. doi request reprint Persisting psychotic-like experiences are associated with both externalising and internalising psychopathology in a longitudinal general population child cohort
    Johnny M Downs
    Department of Forensic and Neurodevelopmental Sciences, Institute of Psychiatry, King s College London, London, United Kingdom
    Schizophr Res 144:99-104. 2013
    ..This prospective study investigated the extent to which PLE persistence was associated with internalising and externalising psychopathology in a community sample of children aged 9-11years at study commencement...
  9. doi request reprint Size matters: increased grey matter in boys with conduct problems and callous-unemotional traits
    Stephane A De Brito
    Department of Forensic Mental Health Science, Institute of Psychiatry, King s College, London, UK
    Brain 132:843-52. 2009
    ..These findings may indicate a delay in cortical maturation in several brain areas implicated in decision making, morality and empathy in boys with callous-unemotional conduct problems...
  10. doi request reprint Cognitive impairment among children at-risk for schizophrenia
    Hannah Dickson
    Department of Forensic and Neurodevelopmental Sciences, Institute of Psychiatry, King s College London, United Kingdom Electronic address
    J Psychiatr Res 50:92-9. 2014
    ..More accurate identification of children at-risk for schizophrenia and the specific deficits that they present provides opportunities for interventions such as cognitive remediation that may impact the development of the illness. ..
  11. ncbi request reprint A supramodal limbic-paralimbic-neocortical network supports goal-directed stimulus processing
    Kristin R Laurens
    Department of Forensic Mental Health Science, Institute of Psychiatry, King s College London, University of London, London, United Kingdom
    Hum Brain Mapp 24:35-49. 2005
    ..Paralimbic cortex offers an important site for the convergence of motivational/goal-directed influences from limbic cortex with stimulus processing and response selection mediated within the frontoparietal areas...
  12. ncbi request reprint Daily stressors and negative life events in children at elevated risk of developing schizophrenia
    Alexis E Cullen
    Alexis E Cullen, MSc, Department of Forensic and Neurodevelopmental Sciences, Institute of Psychiatry, King s College London, UK Helen L Fisher, PhD, CPsychol, AFBPsS, MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, UK Ruth E Roberts, MSc, Department of Forensic and Neurodevelopmental Sciences, Institute of Psychiatry, King s College London, UK Carmine M Pariante, MD, MRCPsych, PhD, Section of Stress, Psychiatry and Immunology and Perinatal Psychiatry, Department of Psychological Medicine, Institute of Psychiatry, King s College London, UK Kristin R Laurens, PhD, Department of Forensic and Neurodevelopmental Sciences, Institute of Psychiatry, King s College London, UK, and Research Unit for Schizophrenia Epidemiology, School of Psychiatry, University of New South Wales, and Schizophrenia Research Institute, Sydney, Australia
    Br J Psychiatry 204:354-60. 2014
    ..Conclusions Stress exposure and reactivity may constitute useful targets of early intervention for psychosis. ..
  13. ncbi request reprint Abnormal function of the brain system supporting motivated attention in medicated patients with schizophrenia: an fMRI study
    Peter F Liddle
    Department of Psychiatry, University of British Columbia, Vancouver BC, Canada
    Psychol Med 36:1097-108. 2006
    ..Patients with schizophrenia have an impaired ability to generate activity that is appropriate to current circumstances and goals...
  14. ncbi request reprint Brain potentials implicate temporal lobe abnormalities in criminal psychopaths
    Kent A Kiehl
    Clinical Cognitive Neuroscience Laboratory, Olin Neuropsychiatry Research Center, Institute of Living, Hartford, CT 06106, USA
    J Abnorm Psychol 115:443-53. 2006
    ..The data are interpreted as supporting the hypothesis that psychopathy may be related to dysfunction of the paralimbic system--a system that includes parts of the temporal and frontal lobes...
  15. ncbi request reprint Rostral anterior cingulate cortex dysfunction during error processing in schizophrenia
    Kristin R Laurens
    Department of Psychiatry, University of British Columbia, Vancouver, Canada
    Brain 126:610-22. 2003
    ....
  16. ncbi request reprint Abnormal processing of speech during oddball target detection in schizophrenia
    Elton T C Ngan
    Department of Psychiatry, University of British Columbia, Vancouver, Canada
    Neuroimage 20:889-97. 2003
    ....
  17. ncbi request reprint An adaptive reflexive processing model of neurocognitive function: supporting evidence from a large scale (n = 100) fMRI study of an auditory oddball task
    Kent A Kiehl
    Olin Neuropsychiatry Research Center, The Institute of Living, Hartford, CT 06106, USA
    Neuroimage 25:899-915. 2005
    ..This process may be termed 'adaptive reflexive processing.' The implications of these results for interpreting functional MRI studies are discussed...
  18. ncbi request reprint Error-related negativity and correct response negativity in schizophrenia
    Alan T Bates
    Department of Psychiatry, University of British Columbia, BC, Vancouver, Canada
    Clin Neurophysiol 113:1454-63. 2002
    ..To examine error-related negativity (ERN) and correct response negativity (CRN) in schizophrenia in light of two previous conflicting reports, and to determine their relation to disorganization, psychomotor poverty and reality distortion...