Kristin R Laurens

Summary

Affiliation: King's College London
Country: UK

Publications

  1. doi request reprint Psychotic-like experiences in a community sample of 8000 children aged 9 to 11 years: an item response theory analysis
    K R Laurens
    Research Unit for Schizophrenia Epidemiology, School of Psychiatry, University of New South Wales, Sydney, Australia
    Psychol Med 42:1495-506. 2012
  2. doi request reprint Error-related processing dysfunction in children aged 9 to 12 years presenting putative antecedents of schizophrenia
    Kristin R Laurens
    Department of Forensic Mental Health Science, Institute of Psychiatry, King s College London, London SE5 8AF, United Kingdom
    Biol Psychiatry 67:238-45. 2010
  3. pmc Mismatch negativity (MMN) and sensory auditory processing in children aged 9-12 years presenting with putative antecedents of schizophrenia
    Jason M Bruggemann
    School of Psychiatry, University of New South Wales, Sydney, Australia Neuroscience Research Australia, Sydney, Australia
    Int J Psychophysiol 89:374-80. 2013
  4. doi request reprint Amygdala hypoactivity to fearful faces in boys with conduct problems and callous-unemotional traits
    Alice P Jones
    Medical Research Council s Social, Genetic, and Developmental Psychiatry Centre, Department of Forensic Mental Health, Institute of Psychiatry, King s College London, UK
    Am J Psychiatry 166:95-102. 2009
  5. ncbi request reprint Neurocognitive performance in children aged 9-12 years who present putative antecedents of schizophrenia
    Alexis E Cullen
    King s College London, Department of Forensic and Neurodevelopmental Sciences Box P023, Institute of Psychiatry, De Crespigny Park, London SE5 8AF, United Kingdom
    Schizophr Res 121:15-23. 2010
  6. doi request reprint Systematic meta-analysis of childhood social withdrawal in schizophrenia, and comparison with data from at-risk children aged 9-14 years
    Sandra L Matheson
    Schizophrenia Research Institute, Level 7, 45 Liverpool Street, Darlinghurst, NSW 2010, Sydney, Australia
    J Psychiatr Res 47:1061-8. 2013
  7. doi request reprint Persisting psychotic-like experiences are associated with both externalising and internalising psychopathology in a longitudinal general population child cohort
    Johnny M Downs
    Department of Forensic and Neurodevelopmental Sciences, Institute of Psychiatry, King s College London, London, United Kingdom
    Schizophr Res 144:99-104. 2013
  8. pmc Cortisol awakening response and diurnal cortisol among children at elevated risk for schizophrenia: relationship to psychosocial stress and cognition
    Alexis E Cullen
    Department of Forensic and Neurodevelopmental Sciences Box P023, Institute of Psychiatry, De Crespigny Park, London SE5 8AF, United Kingdom Electronic address
    Psychoneuroendocrinology 46:1-13. 2014
  9. doi request reprint Systematic meta-analysis of insula volume in schizophrenia
    Alana M Shepherd
    University of New South Wales Research Unit for Schizophrenia Epidemiology, School of Psychiatry, Sydney, Australia
    Biol Psychiatry 72:775-84. 2012
  10. ncbi request reprint Community screening for psychotic-like experiences and other putative antecedents of schizophrenia in children aged 9-12 years
    Kristin R Laurens
    Department of Forensic Mental Health Science, Institute of Psychiatry, King s College London, Box P023, De Crespigny Park, London SE5 8AF, UK
    Schizophr Res 90:130-46. 2007

Detail Information

Publications14

  1. doi request reprint Psychotic-like experiences in a community sample of 8000 children aged 9 to 11 years: an item response theory analysis
    K R Laurens
    Research Unit for Schizophrenia Epidemiology, School of Psychiatry, University of New South Wales, Sydney, Australia
    Psychol Med 42:1495-506. 2012
    ..Nevertheless, these experiences confer increased risk for later psychotic disorder, and are associated with poorer health and quality of life...
  2. doi request reprint Error-related processing dysfunction in children aged 9 to 12 years presenting putative antecedents of schizophrenia
    Kristin R Laurens
    Department of Forensic Mental Health Science, Institute of Psychiatry, King s College London, London SE5 8AF, United Kingdom
    Biol Psychiatry 67:238-45. 2010
    ..This study examined whether ASz children display brain function abnormalities during error processing that are similar to those exhibited by adults with schizophrenia...
  3. pmc Mismatch negativity (MMN) and sensory auditory processing in children aged 9-12 years presenting with putative antecedents of schizophrenia
    Jason M Bruggemann
    School of Psychiatry, University of New South Wales, Sydney, Australia Neuroscience Research Australia, Sydney, Australia
    Int J Psychophysiol 89:374-80. 2013
    ..This may reflect developmental and disease effects in a pre-prodromal phase of psychosis onset. Longitudinal follow-up is necessary to establish the developmental trajectory of MMN in at-risk children...
  4. doi request reprint Amygdala hypoactivity to fearful faces in boys with conduct problems and callous-unemotional traits
    Alice P Jones
    Medical Research Council s Social, Genetic, and Developmental Psychiatry Centre, Department of Forensic Mental Health, Institute of Psychiatry, King s College London, UK
    Am J Psychiatry 166:95-102. 2009
    ..Using functional MRI, the authors evaluated differences in neural response to emotional stimuli between boys with conduct problems and elevated levels of callous-unemotional traits and comparison boys...
  5. ncbi request reprint Neurocognitive performance in children aged 9-12 years who present putative antecedents of schizophrenia
    Alexis E Cullen
    King s College London, Department of Forensic and Neurodevelopmental Sciences Box P023, Institute of Psychiatry, De Crespigny Park, London SE5 8AF, United Kingdom
    Schizophr Res 121:15-23. 2010
    ..The present study aimed to determine whether ASz children also present neurocognitive deficits that are commonly observed in patients with schizophrenia...
  6. doi request reprint Systematic meta-analysis of childhood social withdrawal in schizophrenia, and comparison with data from at-risk children aged 9-14 years
    Sandra L Matheson
    Schizophrenia Research Institute, Level 7, 45 Liverpool Street, Darlinghurst, NSW 2010, Sydney, Australia
    J Psychiatr Res 47:1061-8. 2013
    ..442, p = 0.051). Childhood social withdrawal may constitute a vulnerability marker for schizophrenia in the presence of other antecedents and/or genetic risk factors for schizophrenia...
  7. doi request reprint Persisting psychotic-like experiences are associated with both externalising and internalising psychopathology in a longitudinal general population child cohort
    Johnny M Downs
    Department of Forensic and Neurodevelopmental Sciences, Institute of Psychiatry, King s College London, London, United Kingdom
    Schizophr Res 144:99-104. 2013
    ..This prospective study investigated the extent to which PLE persistence was associated with internalising and externalising psychopathology in a community sample of children aged 9-11years at study commencement...
  8. pmc Cortisol awakening response and diurnal cortisol among children at elevated risk for schizophrenia: relationship to psychosocial stress and cognition
    Alexis E Cullen
    Department of Forensic and Neurodevelopmental Sciences Box P023, Institute of Psychiatry, De Crespigny Park, London SE5 8AF, United Kingdom Electronic address
    Psychoneuroendocrinology 46:1-13. 2014
    ..We speculate that the blunted CAR may constitute an early (potentially genetically mediated) marker of psychosis vulnerability, whilst elevated diurnal cortisol levels may emerge only proximally to disease onset. ..
  9. doi request reprint Systematic meta-analysis of insula volume in schizophrenia
    Alana M Shepherd
    University of New South Wales Research Unit for Schizophrenia Epidemiology, School of Psychiatry, Sydney, Australia
    Biol Psychiatry 72:775-84. 2012
    ..We provide the first meta-analysis of studies that conducted region-of-interest analyses of the magnitude of effect and pattern of insula volume reduction in schizophrenia compared with healthy control subjects...
  10. ncbi request reprint Community screening for psychotic-like experiences and other putative antecedents of schizophrenia in children aged 9-12 years
    Kristin R Laurens
    Department of Forensic Mental Health Science, Institute of Psychiatry, King s College London, Box P023, De Crespigny Park, London SE5 8AF, UK
    Schizophr Res 90:130-46. 2007
    ..The results suggest that questionnaire screening of community samples of children for the putative antecedents of schizophrenia spectrum disorders is feasible. Accuracy of identification will only be established by follow-up studies...
  11. doi request reprint Cognitive impairment among children at-risk for schizophrenia
    Hannah Dickson
    Department of Forensic and Neurodevelopmental Sciences, Institute of Psychiatry, King s College London, United Kingdom Electronic address
    J Psychiatr Res 50:92-9. 2014
    ..More accurate identification of children at-risk for schizophrenia and the specific deficits that they present provides opportunities for interventions such as cognitive remediation that may impact the development of the illness. ..
  12. doi request reprint Size matters: increased grey matter in boys with conduct problems and callous-unemotional traits
    Stephane A De Brito
    Department of Forensic Mental Health Science, Institute of Psychiatry, King s College, London, UK
    Brain 132:843-52. 2009
    ..These findings may indicate a delay in cortical maturation in several brain areas implicated in decision making, morality and empathy in boys with callous-unemotional conduct problems...
  13. doi request reprint Systematic meta-review and quality assessment of the structural brain alterations in schizophrenia
    Alana M Shepherd
    University of New South Wales Research Unit for Schizophrenia Epidemiology, O Brien Centre at St Vincent s Hospital, 394 404 Victoria Street, Darlinghurst, Sydney, NSW 2010, Australia
    Neurosci Biobehav Rev 36:1342-56. 2012
    ..This meta-review synthesises the available information from systematic reviews of structural alteration in both chronic and first-episode schizophrenia...
  14. ncbi request reprint Daily stressors and negative life events in children at elevated risk of developing schizophrenia
    Alexis E Cullen
    Alexis E Cullen, MSc, Department of Forensic and Neurodevelopmental Sciences, Institute of Psychiatry, King s College London, UK Helen L Fisher, PhD, CPsychol, AFBPsS, MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, UK Ruth E Roberts, MSc, Department of Forensic and Neurodevelopmental Sciences, Institute of Psychiatry, King s College London, UK Carmine M Pariante, MD, MRCPsych, PhD, Section of Stress, Psychiatry and Immunology and Perinatal Psychiatry, Department of Psychological Medicine, Institute of Psychiatry, King s College London, UK Kristin R Laurens, PhD, Department of Forensic and Neurodevelopmental Sciences, Institute of Psychiatry, King s College London, UK, and Research Unit for Schizophrenia Epidemiology, School of Psychiatry, University of New South Wales, and Schizophrenia Research Institute, Sydney, Australia
    Br J Psychiatry 204:354-60. 2014
    ..Conclusions Stress exposure and reactivity may constitute useful targets of early intervention for psychosis. ..