Jonna Kuntsi

Summary

Affiliation: King's College London
Country: UK

Publications

  1. ncbi request reprint Genetic influences on mechanically-assessed activity level in children
    Alexis C Wood
    MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Kings College London, UK
    J Child Psychol Psychiatry 48:695-702. 2007
  2. pmc Functional MRI in ADHD: a systematic literature review
    Yannis Paloyelis
    MRC Social Genetic Developmental Psychiatry Centre P080, Institute of Psychiatry, De Crespigny Park, London, SE5 8AF, UK
    Expert Rev Neurother 7:1337-56. 2007
  3. ncbi request reprint Attention deficit hyperactivity disorder
    Jonna Kuntsi
    MRC Social, Genetic, and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, De Crespigny Park, London SE5 8AF, UK
    Neuromolecular Med 8:461-84. 2006
  4. pmc Reaction time, inhibition, working memory and 'delay aversion' performance: genetic influences and their interpretation
    Jonna Kuntsi
    MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, UK
    Psychol Med 36:1613-24. 2006
  5. pmc Testing assumptions for endophenotype studies in ADHD: reliability and validity of tasks in a general population sample
    Jonna Kuntsi
    MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, De Crespigny Park, London SE5 8AF, UK
    BMC Psychiatry 5:40. 2005
  6. ncbi request reprint Genetic influences on the stability of attention-deficit/hyperactivity disorder symptoms from early to middle childhood
    Jonna Kuntsi
    MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, London, United Kingdom
    Biol Psychiatry 57:647-54. 2005
  7. pmc Separation of cognitive impairments in attention-deficit/hyperactivity disorder into 2 familial factors
    Jonna Kuntsi
    MRC Social, Genetic, and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, London SE5 8AF, United Kingdom
    Arch Gen Psychiatry 67:1159-67. 2010
  8. pmc Cognitive-electrophysiological indices of attentional and inhibitory processing in adults with ADHD: familial effects
    Gráinne McLoughlin
    MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, De Crespigny Park, London SE5 8AF, UK
    Behav Brain Funct 7:26. 2011
  9. ncbi request reprint The separation of ADHD inattention and hyperactivity-impulsivity symptoms: pathways from genetic effects to cognitive impairments and symptoms
    Jonna Kuntsi
    MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, De Crespigny Park, London, SE5 8AF, UK
    J Abnorm Child Psychol 42:127-36. 2014
  10. doi request reprint Is overactivity a core feature in ADHD? Familial and receiver operating characteristic curve analysis of mechanically assessed activity level
    Alexis C Wood
    Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, London, UK
    J Am Acad Child Adolesc Psychiatry 48:1023-30. 2009

Detail Information

Publications39

  1. ncbi request reprint Genetic influences on mechanically-assessed activity level in children
    Alexis C Wood
    MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Kings College London, UK
    J Child Psychol Psychiatry 48:695-702. 2007
    ..Yet it is poorly understood, due partly to limitations on parent and teacher ratings, which are typically used as measurements of these symptoms...
  2. pmc Functional MRI in ADHD: a systematic literature review
    Yannis Paloyelis
    MRC Social Genetic Developmental Psychiatry Centre P080, Institute of Psychiatry, De Crespigny Park, London, SE5 8AF, UK
    Expert Rev Neurother 7:1337-56. 2007
    ....
  3. ncbi request reprint Attention deficit hyperactivity disorder
    Jonna Kuntsi
    MRC Social, Genetic, and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, De Crespigny Park, London SE5 8AF, UK
    Neuromolecular Med 8:461-84. 2006
    ..Such research is only at its beginning, but is illustrated by recent findings of an association between DAT1 and increased response variability in ADHD...
  4. pmc Reaction time, inhibition, working memory and 'delay aversion' performance: genetic influences and their interpretation
    Jonna Kuntsi
    MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, UK
    Psychol Med 36:1613-24. 2006
    ..We further aimed to illustrate how test-retest reliability of the measures affects the estimates...
  5. pmc Testing assumptions for endophenotype studies in ADHD: reliability and validity of tasks in a general population sample
    Jonna Kuntsi
    MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, De Crespigny Park, London SE5 8AF, UK
    BMC Psychiatry 5:40. 2005
    ....
  6. ncbi request reprint Genetic influences on the stability of attention-deficit/hyperactivity disorder symptoms from early to middle childhood
    Jonna Kuntsi
    MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, London, United Kingdom
    Biol Psychiatry 57:647-54. 2005
    ....
  7. pmc Separation of cognitive impairments in attention-deficit/hyperactivity disorder into 2 familial factors
    Jonna Kuntsi
    MRC Social, Genetic, and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, London SE5 8AF, United Kingdom
    Arch Gen Psychiatry 67:1159-67. 2010
    ..A better understanding of the etiological pathways is important for the development of targeted interventions and for identification of suitable intermediate phenotypes for molecular genetic investigations...
  8. pmc Cognitive-electrophysiological indices of attentional and inhibitory processing in adults with ADHD: familial effects
    Gráinne McLoughlin
    MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, De Crespigny Park, London SE5 8AF, UK
    Behav Brain Funct 7:26. 2011
    ..We now compare these data further to additional data from first-degree relatives (fathers) of children with ADHD to identify whether this pattern of abnormal processing shares familial influences with ADHD in adults...
  9. ncbi request reprint The separation of ADHD inattention and hyperactivity-impulsivity symptoms: pathways from genetic effects to cognitive impairments and symptoms
    Jonna Kuntsi
    MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, De Crespigny Park, London, SE5 8AF, UK
    J Abnorm Child Psychol 42:127-36. 2014
    ..The findings extend a previous model of two familial cognitive impairment factors in combined subtype ADHD by separating pathways underlying inattention and hyperactivity-impulsivity symptoms. ..
  10. doi request reprint Is overactivity a core feature in ADHD? Familial and receiver operating characteristic curve analysis of mechanically assessed activity level
    Alexis C Wood
    Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, London, UK
    J Am Acad Child Adolesc Psychiatry 48:1023-30. 2009
    ..Furthermore, we aimed to investigate the degree of shared familial influences on these measures and the ADHD diagnosis...
  11. pmc Hyperactive-impulsive symptom scores and oppositional behaviours reflect alternate manifestations of a single liability
    Alexis C Wood
    MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Kings College London, De Crespigny Park, London, SE5 8AF, UK
    Behav Genet 39:447-60. 2009
    ..In middle childhood, symptoms of hyperactivity-impulsivity and oppositional behaviour may represent the same underlying liability, whereas the inattentive domain is more distinct...
  12. pmc Why cognitive performance in ADHD may not reveal true potential: findings from a large population-based sample
    Jonna Kuntsi
    MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, De Crespigny Park Box P080, London SE5 8AF, UK
    J Int Neuropsychol Soc 15:570-9. 2009
    ..The degree to which cognitive impairments in ADHD can be modulated by energetic or motivational factors has important implications for clinical and educational interventions...
  13. pmc High heritability for a composite index of children's activity level measures
    Alexis C Wood
    Social, Genetic and Developmental Psychiatry, Institute of Psychiatry, P O Box 80, De Crespigny Park, London SE5 8AF, UK
    Behav Genet 38:266-76. 2008
    ..The high heritabilities found are encouraging in this respect...
  14. pmc Striatal sensitivity during reward processing in attention-deficit/hyperactivity disorder
    Yannis Paloyelis
    King s College London, Medical Research Council Social Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, UK
    J Am Acad Child Adolesc Psychiatry 51:722-732.e9. 2012
    ..We investigated striatal responsivity to rewards in ADHD combined type (ADHD-CT) using functional magnetic resonance imaging (fMRI), and whether it is modulated by variation in the dopamine transporter gene (DAT1)...
  15. pmc Aetiology for the covariation between combined type ADHD and reading difficulties in a family study: the role of IQ
    Celeste H M Cheung
    King s College London, MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, London, UK
    J Child Psychol Psychiatry 53:864-73. 2012
    ..This study investigated the familial relationships between ADHD, reading difficulties and IQ in a sample of individuals diagnosed with ADHD combined type, their siblings and control sibling pairs...
  16. pmc Electrophysiological evidence for abnormal preparatory states and inhibitory processing in adult ADHD
    Gráinne McLoughlin
    MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, UK
    Behav Brain Funct 6:66. 2010
    ..It is not yet known if this pattern of abnormal processing is evident in adult ADHD...
  17. pmc Genetic support for the dual nature of attention deficit hyperactivity disorder: substantial genetic overlap between the inattentive and hyperactive-impulsive components
    Gráinne McLoughlin
    MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, De Crespigny Park, London, UK
    J Abnorm Child Psychol 35:999-1008. 2007
    ..This study investigated, in a community sample, the aetiology of ADHD-like traits and the aetiological overlap between the two dimensions that define the ADHD disorder...
  18. pmc Performance monitoring is altered in adult ADHD: a familial event-related potential investigation
    Gráinne McLoughlin
    MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, De Crespigny Park, London SE58AF, UK
    Neuropsychologia 47:3134-42. 2009
    ..It is not yet known whether these processes show the same abnormalities and familial effects in adults...
  19. pmc Shared genetic influences on ADHD symptoms and very low-frequency EEG activity: a twin study
    Charlotte Tye
    MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, De Crespigny Park, London, UK
    J Child Psychol Psychiatry 53:706-15. 2012
    ..Very low-frequency (VLF; <0.5 Hz) electroencephalographic (EEG) activity represents a promising indicator of risk for ADHD, but it currently remains unclear as to whether it is heritable or genetically linked to the disorder...
  20. pmc DAT1 and COMT effects on delay discounting and trait impulsivity in male adolescents with attention deficit/hyperactivity disorder and healthy controls
    Yannis Paloyelis
    MRC SDGP Centre, Institute of Psychiatry, King s College London, London, UK
    Neuropsychopharmacology 35:2414-26. 2010
    ..The lack of magnitude effects in the hypothetical task suggests that discounting in this task may be influenced by different processes in ADHD-CT than in healthy controls...
  21. pmc The genetic association between ADHD symptoms and reading difficulties: the role of inattentiveness and IQ
    Yannis Paloyelis
    MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, UK
    J Abnorm Child Psychol 38:1083-95. 2010
    ....
  22. ncbi request reprint DSM-IV combined type ADHD shows familial association with sibling trait scores: a sampling strategy for QTL linkage
    Wai Chen
    MRC Social Genetic Developmental and Psychiatry Centre, Institute of Psychiatry, London, United Kingdom
    Am J Med Genet B Neuropsychiatr Genet 147:1450-60. 2008
    ..In conclusion, these data confirm the main requirement for QTL mapping of ADHD by demonstrating that narrowly defined DSM-IV combined type probands show familial association with dimensional ADHD symptom scores amongst their siblings...
  23. ncbi request reprint Evidence for overlapping genetic influences on autistic and ADHD behaviours in a community twin sample
    Angelica Ronald
    Social Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, London, UK
    J Child Psychol Psychiatry 49:535-42. 2008
    ..This study takes an individual differences approach to determine the degree of phenotypic and aetiological overlap between autistic traits and ADHD behaviours in the general population...
  24. doi request reprint The effect of methylphenidate on very low frequency electroencephalography oscillations in adult ADHD
    Ruth E Cooper
    King s College London, MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, UK Electronic address
    Brain Cogn 86:82-9. 2014
    ..Further studies of the treatment effect of MPH in larger controlled studies are required to formally evaluate any causal link between MPH, VLF-EEG and ADHD symptoms. ..
  25. pmc Reaction time performance in ADHD: improvement under fast-incentive condition and familial effects
    Penny Andreou
    MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, UK
    Psychol Med 37:1703-15. 2007
    ..Using a group familial correlation approach, we tested the hypothesis that there are shared familial effects on RT performance and ADHD...
  26. pmc Electrophysiological markers of genetic risk for attention deficit hyperactivity disorder
    Charlotte Tye
    MRC Social Genetic Developmental Psychiatry Centre SGDP, Institute of Psychiatry, London, UK
    Expert Rev Mol Med 13:e9. 2011
    ..Such research will aid in the precise characterisation of the clinical deficits seen in ADHD and guide the development of novel intervention and prevention strategies for those at risk...
  27. pmc Are ADHD symptoms associated with delay aversion or choice impulsivity? A general population study
    Yannis Paloyelis
    Medical Research Council Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, London, UK
    J Am Acad Child Adolesc Psychiatry 48:837-46. 2009
    ..In this study, we examined the association of attention-deficit/hyperactivity disorder (ADHD) symptoms with choice impulsivity and tested the specific hypothesis derived from delay aversion theory...
  28. pmc Actigraph data are reliable, with functional reliability increasing with aggregation
    Alexis C Wood
    Institute of Psychiatry, Kings College London, London, England
    Behav Res Methods 40:873-8. 2008
    ..We also examined possible instrumental effects on actigraph data and found these to be nonsignificant, further supporting the reliability and validity of actigraph data as a method of activity level assessment...
  29. doi request reprint Genetic associations between the symptoms of attention-deficit/hyperactivity disorder and emotional lability in child and adolescent twins
    Andrew Merwood
    King s College London, Medical Research Council MRC Social Genetic and Developmental Psychiatry Centre, London, UK University of Bath, Bath, UK Electronic address
    J Am Acad Child Adolesc Psychiatry 53:209-220.e4. 2014
    ..The present study examines these associations in a large, community twin sample...
  30. pmc Rates of undiagnosed attention deficit hyperactivity disorder in London drug and alcohol detoxification units
    Zoe Huntley
    MRC Social Genetic and Developmental Psychiatry, Institute of Psychiatry, Kings College London, London, SE 58AF, UK
    BMC Psychiatry 12:223. 2012
    ..One of the most prevalent and impairing comorbidities of ADHD in adults are substance use disorders. We estimate rates of ADHD in patients with substance abuse disorders and delineate impairment in the co-morbid group...
  31. doi request reprint Behavioral, neurocognitive and treatment overlap between attention-deficit/hyperactivity disorder and mood instability
    Caroline Skirrow
    MRC Social Genetic Developmental Psychiatry Centre, Institute of Psychiatry, De Crespigny Park, London, SE5 8AF, UK
    Expert Rev Neurother 9:489-503. 2009
    ..This research suggests that mood instability and symptoms of ADHD may be interlinked and that mood instability may be better understood as a core feature of the ADHD syndrome...
  32. pmc Protection from genetic diathesis in attention-deficit/hyperactivity disorder: possible complementary roles of exercise
    Anna Sophie Rommel
    Medical Research Council Social, Genetic and Developmental Psychiatry Centre, The Institute of Psychiatry, King s College London
    J Am Acad Child Adolesc Psychiatry 52:900-10. 2013
    ..Findings on the impact of exercise in animals and typically developing human beings, and an overview of putative mechanisms involved, are also presented to provide the context in which to understand this review...
  33. pmc Shared cognitive impairments and aetiology in ADHD symptoms and reading difficulties
    Celeste H M Cheung
    MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, London, United Kingdom
    PLoS ONE 9:e98590. 2014
    ..We address this question using a sample of twins aged 7-10 and a range of cognitive measures previously associated with ADHD symptoms or RD...
  34. ncbi request reprint Intelligence in DSM-IV combined type attention-deficit/hyperactivity disorder is not predicted by either dopamine receptor/transporter genes or other previously identified risk alleles for attention-deficit/hyperactivity disorder
    Edmund J S Sonuga-Barke
    School of Psychology, University of Southampton, Southampton, UK
    Am J Med Genet B Neuropsychiatr Genet 147:316-9. 2008
    ..We also observed no association of other SNPs with IQ in ADHD...
  35. ncbi request reprint Unravelling the complexity of attention-deficit hyperactivity disorder: a behavioural genomic approach
    Philip Asherson
    Br J Psychiatry 187:103-5. 2005
    ..A major challenge for the field now is to clarify how genetic susceptibility is translated into disorder by integrating the fields of quantitative and molecular genetics, neuropsychology and environmental risks...
  36. ncbi request reprint Continuity and change in preschool ADHD symptoms: longitudinal genetic analysis with contrast effects
    Thomas S Price
    Wellcome Trust Centre for Human Genetics, University of Oxford, UK
    Behav Genet 35:121-32. 2005
    ..Contrast effects acting in the same direction at different ages contributed to the observed continuity:longitudinal correlations were greater for dizygotic than monozygotic twins...
  37. ncbi request reprint Face and emotion recognition deficits in Turner syndrome: a possible role for X-linked genes in amygdala development
    Kate Lawrence
    Department of Behavioural and Brain Sciences, Institute of Child Health, University College London, England
    Neuropsychology 17:39-49. 2003
    ..The authors therefore suggest that anomalies in amygdala function may be a neurological feature of TS of this karyotype...
  38. ncbi request reprint The classification of 'fear' from faces is associated with face recognition skill in women
    Ruth Campbell
    Department of Human Communication Science, University College London, Chandler House, 2 Wakefield Street, London WC1N 1 PF, UK
    Neuropsychologia 40:575-84. 2002
    ..We speculate that social learning, which involves identifying the faces of potentially salient others, and also their attitude to the observer, engages the amygdala more readily in women than in men...