R Killick

Summary

Affiliation: King's College London
Country: UK

Publications

  1. pmc Wnt3a induces exosome secretion from primary cultured rat microglia
    Claudie Hooper
    King s College London, MRC Centre for Neurodegenerative Research, Institute of Psychiatry, De Crespigny Park, Denmark Hill, London SE5 8AF, UK
    BMC Neurosci 13:144. 2012
  2. pmc Deletion of Crry, the murine ortholog of the sporadic Alzheimer's disease risk gene CR1, impacts tau phosphorylation and brain CFH
    R Killick
    King s College London, Institute of Psychiatry, De Crespigny Park, Denmark Hill, London SE5 8AF, UK
    Neurosci Lett 533:96-9. 2013
  3. ncbi request reprint Does dysregulation of the Notch and wingless/Wnt pathways underlie the pathogenesis of Alzheimer's disease?
    B H Anderton
    Department of Neuroscience, Institute of Psychiatry, King s College London, De Crespigny Park, London, UK SE5 8AF
    Mol Med Today 6:54-9. 2000
  4. ncbi request reprint Dishevelled regulates the metabolism of amyloid precursor protein via protein kinase C/mitogen-activated protein kinase and c-Jun terminal kinase
    A Mudher
    Departments of Neuroscience and Psychiatry, Institute of Psychiatry, King's College London, London SE5 8AF, United Kingdom
    J Neurosci 21:4987-95. 2001
  5. ncbi request reprint Presenilin 1 independently regulates beta-catenin stability and transcriptional activity
    R Killick
    Department of Neuroscience, Institute of Psychiatry, King s College London, De Crespigny Park, Denmark Hill, London SE5 8AF, United Kingdom
    J Biol Chem 276:48554-61. 2001

Collaborators

Detail Information

Publications5

  1. pmc Wnt3a induces exosome secretion from primary cultured rat microglia
    Claudie Hooper
    King s College London, MRC Centre for Neurodegenerative Research, Institute of Psychiatry, De Crespigny Park, Denmark Hill, London SE5 8AF, UK
    BMC Neurosci 13:144. 2012
    ..Here we describe the inducible release of exosomes from primary cultured rat microglia following treatment with recombinant carrier-free Wnt3a...
  2. pmc Deletion of Crry, the murine ortholog of the sporadic Alzheimer's disease risk gene CR1, impacts tau phosphorylation and brain CFH
    R Killick
    King s College London, Institute of Psychiatry, De Crespigny Park, Denmark Hill, London SE5 8AF, UK
    Neurosci Lett 533:96-9. 2013
    ..These observations provide a starting point for further attempts to determine the role of CR1 in the neuropathological process driving Alzheimer's disease...
  3. ncbi request reprint Does dysregulation of the Notch and wingless/Wnt pathways underlie the pathogenesis of Alzheimer's disease?
    B H Anderton
    Department of Neuroscience, Institute of Psychiatry, King s College London, De Crespigny Park, London, UK SE5 8AF
    Mol Med Today 6:54-9. 2000
    ..Recent genetic discoveries provide some clues, suggesting that components of two developmentally important signalling pathways, Notch and wingless, or the vertebrate homologue of wingless, Wnt, are involved...
  4. ncbi request reprint Dishevelled regulates the metabolism of amyloid precursor protein via protein kinase C/mitogen-activated protein kinase and c-Jun terminal kinase
    A Mudher
    Departments of Neuroscience and Psychiatry, Institute of Psychiatry, King's College London, London SE5 8AF, United Kingdom
    J Neurosci 21:4987-95. 2001
    ..Furthermore, we show that human dvl-1 and wnt-1 also reduce the phosphorylation of tau by GSK-3beta. Therefore, both APP metabolism and tau phosphorylation are potentially linked through wnt signaling...
  5. ncbi request reprint Presenilin 1 independently regulates beta-catenin stability and transcriptional activity
    R Killick
    Department of Neuroscience, Institute of Psychiatry, King s College London, De Crespigny Park, Denmark Hill, London SE5 8AF, United Kingdom
    J Biol Chem 276:48554-61. 2001
    ....