Wafa Khamri

Summary

Affiliation: King's College London
Country: UK

Publications

  1. ncbi Expression of surfactant protein D in the human gastric mucosa and during Helicobacter pylori infection
    Emma Murray
    MRC Immunochemistry Unit, Oxford, United Kingdom
    Infect Immun 70:1481-7. 2002
  2. ncbi Helicobacter infection in the surfactant protein D-deficient mouse
    Wafa Khamri
    Faculty of Medicine, Imperial College, St Mary s Campus, London, UK
    Helicobacter 12:112-23. 2007
  3. ncbi Helicobacter pylori stimulates dendritic cells to induce interleukin-17 expression from CD4+ T lymphocytes
    Wafa Khamri
    Immunoregulation Laboratory, Department of Nephrology and Transplantation, 5th Floor Thomas Guy House, Guy s Hospital Campus, King s College London School of Medicine at Guy s, London SE1 9RT, United Kingdom
    Infect Immun 78:845-53. 2010
  4. ncbi TLR9 polymorphisms determine murine lymphocyte responses to Helicobacter: results from a genome-wide scan
    Amy E Anderson
    Gastroenterology and Hepatology Research, Division of Medicine, Faculty of Medicine, Imperial College London, London, UK
    Eur J Immunol 37:1548-61. 2007
  5. ncbi Chronic exposure to Helicobacter pylori impairs dendritic cell function and inhibits Th1 development
    Peter Mitchell
    Department of Immunology, Division of Medicine, Faculty of Medicine, Imperial College at Hammersmith Hospital, London, United Kingdom
    Infect Immun 75:810-9. 2007
  6. ncbi Variations in Helicobacter pylori lipopolysaccharide to evade the innate immune component surfactant protein D
    Wafa Khamri
    Imperial College Faculty of Medicine, St Mary s Campus, Norfolk Place, London, W2 1PG, United Kingdom
    Infect Immun 73:7677-86. 2005
  7. ncbi Expression of complement components, receptors and regulators by human dendritic cells
    Ke Li
    King s College London, MRC Centre for Transplantation, NIHR Comprehensive Biomedical Research Centre, Guy s Hospital, London, UK
    Mol Immunol 48:1121-7. 2011
  8. ncbi Role of surfactant protein D (SP-D) in innate immunity in the gastric mucosa: evidence of interaction with Helicobacter pylori lipopolysaccharide
    Anthony P Moran
    Department of Microbiology, National University of Ireland, Galway, Ireland
    J Endotoxin Res 11:357-62. 2005

Collaborators

  • Steven H Sacks
  • Graham R Foster
  • Wuding Zhou
  • A P Moran
  • M M Walker
  • Sam Hawgood
  • Ke Li
  • Giovanna Lombardi
  • Amy E Anderson
  • Kathleen B Bamford
  • Peter Mitchell
  • Mark R Thursz
  • Emma Murray
  • Chantelle Gomes
  • Qi Peng
  • Naiyin Wang
  • Henrieta Fazekasova
  • Pervinder Sagoo
  • Conrad Germain
  • Pier Luigi Fiori
  • Robert I Lechler
  • Subrata Ghosh
  • Mulugeta L Worku
  • Peter Strong
  • John A Ferris
  • Kenneth B M Reid
  • Paul Eggleton
  • Susanne Knapp
  • Mulegata Worku
  • Q Najma Karim

Detail Information

Publications8

  1. ncbi Expression of surfactant protein D in the human gastric mucosa and during Helicobacter pylori infection
    Emma Murray
    MRC Immunochemistry Unit, Oxford, United Kingdom
    Infect Immun 70:1481-7. 2002
    ..SP-D may therefore play a significant role in the innate immune response to H. pylori infection...
  2. ncbi Helicobacter infection in the surfactant protein D-deficient mouse
    Wafa Khamri
    Faculty of Medicine, Imperial College, St Mary s Campus, London, UK
    Helicobacter 12:112-23. 2007
    ..SP-D binds to Helicobacter in vitro, suggesting the involvement of SP-D in Helicobacter-induced immune responses. The aim of this study was to determine the role of SP-D in gastric epithelial defense in vivo...
  3. ncbi Helicobacter pylori stimulates dendritic cells to induce interleukin-17 expression from CD4+ T lymphocytes
    Wafa Khamri
    Immunoregulation Laboratory, Department of Nephrology and Transplantation, 5th Floor Thomas Guy House, Guy s Hospital Campus, King s College London School of Medicine at Guy s, London SE1 9RT, United Kingdom
    Infect Immun 78:845-53. 2010
    ..Altogether, we can conclude that DCs are potent inducers of IL-23/IL-17 expression following H. pylori stimulation. IL-1/IL-23 as well as H. pylori virulence factors seem to play an important role in mediating this response...
  4. ncbi TLR9 polymorphisms determine murine lymphocyte responses to Helicobacter: results from a genome-wide scan
    Amy E Anderson
    Gastroenterology and Hepatology Research, Division of Medicine, Faculty of Medicine, Imperial College London, London, UK
    Eur J Immunol 37:1548-61. 2007
    ..Regulation of TLR9 expression and signalling therefore appears to play an important role in the control of lymphocyte responses to Helicobacter and potentially other luminal microorganisms...
  5. ncbi Chronic exposure to Helicobacter pylori impairs dendritic cell function and inhibits Th1 development
    Peter Mitchell
    Department of Immunology, Division of Medicine, Faculty of Medicine, Imperial College at Hammersmith Hospital, London, United Kingdom
    Infect Immun 75:810-9. 2007
    ..Our results raise the possibility that in chronic H. pylori infection DCs become exhausted after prolonged antigen exposure leading to suboptimal Th1 development. This effect may contribute to persistence of H. pylori infection...
  6. ncbi Variations in Helicobacter pylori lipopolysaccharide to evade the innate immune component surfactant protein D
    Wafa Khamri
    Imperial College Faculty of Medicine, St Mary s Campus, Norfolk Place, London, W2 1PG, United Kingdom
    Infect Immun 73:7677-86. 2005
    ..SP-D binding organisms are predominant in mucus in vivo (P = 0.02), suggesting that SP-D facilitates physical elimination. Phase variation to evade SP-D contributes to the persistence of this common gastric pathogen...
  7. ncbi Expression of complement components, receptors and regulators by human dendritic cells
    Ke Li
    King s College London, MRC Centre for Transplantation, NIHR Comprehensive Biomedical Research Centre, Guy s Hospital, London, UK
    Mol Immunol 48:1121-7. 2011
    ..It acts as a resource that allows further understanding and exploitation of role of complement in human health and immune mediated diseases...
  8. ncbi Role of surfactant protein D (SP-D) in innate immunity in the gastric mucosa: evidence of interaction with Helicobacter pylori lipopolysaccharide
    Anthony P Moran
    Department of Microbiology, National University of Ireland, Galway, Ireland
    J Endotoxin Res 11:357-62. 2005
    ..pylori lipopolysaccharide. Furthermore, evidence indicates that H. pylori varies LPS O-chain structure to evade SP-D binding which is speculated aids persistence of this chronic infection...