Research Topics
Species | Matthew J KemptonSummaryAffiliation: King's College London Country: UK Publications
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Detail Information
Publications
A comprehensive testing protocol for MRI neuroanatomical segmentation techniques: Evaluation of a novel lateral ventricle segmentation methodMatthew J Kempton
King s College London, Institute of Psychiatry, Department of Neuroimaging, UK
Neuroimage 58:1051-9. 2011..We also demonstrate that the novel segmentation algorithm and FreeSurfer are both effective in determining lateral ventricular volume and are well suited for multicentre and longitudinal MRI studies...
Structural neuroimaging studies in major depressive disorder. Meta-analysis and comparison with bipolar disorderMatthew J Kempton
Department of Neuroimaging, PO89, Institute of Psychiatry, King s College London, De Crespigny Park, London SE5 8AF, England
Arch Gen Psychiatry 68:675-90. 2011..Although differences in clinical characteristics exist between major depressive disorder (MDD) and bipolar disorder (BD), consistent structural brain abnormalities that distinguish the disorders have not been identified...
Dehydration affects brain structure and function in healthy adolescentsMatthew J Kempton
Centre for Neuroimaging Sciences, Institute of Psychiatry, King s College London, London, SE5 8AF, United Kingdom
Hum Brain Mapp 32:71-9. 2011..Given the limited availability of brain metabolic resources, these findings suggest that prolonged states of reduced water intake may adversely impact executive functions such as planning and visuo-spatial processing...
Effects of acute dehydration on brain morphology in healthy humansMatthew J Kempton
Centre for Neuroimaging Sciences, Institute of Psychiatry, King s College London, London, United Kingdom
Hum Brain Mapp 30:291-8. 2009....
The effects of gender and COMT Val158Met polymorphism on fearful facial affect recognition: a fMRI studyMatthew J Kempton
Section of Neurobiology of Psychosis, Institute of Psychiatry and NIHR Biomedical Research Centre for Mental Health, King s College London, UK
Int J Neuropsychopharmacol 12:371-81. 2009..The COMT Val108/158Met polymorphism impacts on gender-related patterns of activation in limbic and paralimbic regions but the functional significance of any oestrogen-related COMT inhibition appears modest...
Progressive lateral ventricular enlargement in schizophrenia: a meta-analysis of longitudinal MRI studiesMatthew J Kempton
Centre for Neuroimaging Sciences, Institute of Psychiatry, King s College London, UK
Schizophr Res 120:54-62. 2010..To clarify this we conducted a meta-analysis of longitudinal studies measuring the lateral ventricles in patients with schizophrenia and a control group...
Dissociable brain structural changes associated with predisposition, resilience, and disease expression in bipolar disorderMatthew J Kempton
Section of Neurobiology of Psychosis, Institute of Psychiatry, King s College London, London SE5 8AF, United Kingdom
J Neurosci 29:10863-8. 2009....
Meta-analysis, database, and meta-regression of 98 structural imaging studies in bipolar disorderMatthew J Kempton
Centre for Neuroimaging Sciences, Institute of Psychiatry, DeCrespigny Park, London SE5 8AF, England
Arch Gen Psychiatry 65:1017-32. 2008..Despite 25 years of structural imaging in bipolar disorder, brain regions affected in the disorder are ill defined...
Efficacy and safety of second-generation long-acting injections in schizophrenia: a meta-analysis of randomized-controlled trialsPaolo Fusar-Poli
Department of Psychosis Studies, Institute of Psychiatry, King s College London, UK
Int Clin Psychopharmacol 28:57-66. 2013..These data suggest that SGLAI lack an advantage in reducing psychotic symptoms over oral medications. Their potential effects on relapse prevention should be better addressed by future randomized-controlled trials...
Predicting psychosis: meta-analysis of transition outcomes in individuals at high clinical riskPaolo Fusar-Poli
Department of Psychosis Studies, Institute of Psychiatry, King s College London, London, United Kingdom
Arch Gen Psychiatry 69:220-9. 2012..However, the risk of transition to psychosis varies between centers, and some recent work suggests that the risk of transition may be declining...
