Matthew J Kempton

Summary

Affiliation: King's College London
Country: UK

Publications

  1. pmc How can neuroimaging facilitate the diagnosis and stratification of patients with psychosis?
    Matthew J Kempton
    Department of Psychosis Studies, Institute of Psychiatry, King s College London, UK Department of Neuroimaging, PO89, Institute of Psychiatry, King s College London, De Crespigny Park, London SE5 8AF, UK Electronic address
    Eur Neuropsychopharmacol 25:725-32. 2015
  2. pmc A comprehensive testing protocol for MRI neuroanatomical segmentation techniques: Evaluation of a novel lateral ventricle segmentation method
    Matthew J Kempton
    King s College London, Institute of Psychiatry, Department of Neuroimaging, UK
    Neuroimage 58:1051-9. 2011
  3. doi Structural neuroimaging studies in major depressive disorder. Meta-analysis and comparison with bipolar disorder
    Matthew J Kempton
    Department of Neuroimaging, PO89, Institute of Psychiatry, King s College London, De Crespigny Park, London SE5 8AF, England
    Arch Gen Psychiatry 68:675-90. 2011
  4. doi Dehydration affects brain structure and function in healthy adolescents
    Matthew J Kempton
    Centre for Neuroimaging Sciences, Institute of Psychiatry, King s College London, London, SE5 8AF, United Kingdom
    Hum Brain Mapp 32:71-9. 2011
  5. ncbi Effects of acute dehydration on brain morphology in healthy humans
    Matthew J Kempton
    Centre for Neuroimaging Sciences, Institute of Psychiatry, King s College London, London, United Kingdom
    Hum Brain Mapp 30:291-8. 2009
  6. doi The effects of gender and COMT Val158Met polymorphism on fearful facial affect recognition: a fMRI study
    Matthew J Kempton
    Section of Neurobiology of Psychosis, Institute of Psychiatry and NIHR Biomedical Research Centre for Mental Health, King s College London, UK
    Int J Neuropsychopharmacol 12:371-81. 2009
  7. doi Molecular genetic gene-environment studies using candidate genes in schizophrenia: a systematic review
    Gemma Modinos
    Department of Psychosis Studies, Institute of Psychiatry, King s College London, United Kingdom Electronic address
    Schizophr Res 150:356-65. 2013
  8. doi Dissociable brain structural changes associated with predisposition, resilience, and disease expression in bipolar disorder
    Matthew J Kempton
    Section of Neurobiology of Psychosis, Institute of Psychiatry, King s College London, London SE5 8AF, United Kingdom
    J Neurosci 29:10863-8. 2009
  9. doi Meta-analysis, database, and meta-regression of 98 structural imaging studies in bipolar disorder
    Matthew J Kempton
    Centre for Neuroimaging Sciences, Institute of Psychiatry, DeCrespigny Park, London SE5 8AF, England
    Arch Gen Psychiatry 65:1017-32. 2008
  10. doi Progressive lateral ventricular enlargement in schizophrenia: a meta-analysis of longitudinal MRI studies
    Matthew J Kempton
    Centre for Neuroimaging Sciences, Institute of Psychiatry, King s College London, UK
    Schizophr Res 120:54-62. 2010

Collaborators

Detail Information

Publications16

  1. pmc How can neuroimaging facilitate the diagnosis and stratification of patients with psychosis?
    Matthew J Kempton
    Department of Psychosis Studies, Institute of Psychiatry, King s College London, UK Department of Neuroimaging, PO89, Institute of Psychiatry, King s College London, De Crespigny Park, London SE5 8AF, UK Electronic address
    Eur Neuropsychopharmacol 25:725-32. 2015
    ..As many of these developments are already being applied in neuroimaging studies of Alzheimer's disease, we discuss what lessons have been learned from this field and how they may be applied to research in psychosis...
  2. pmc A comprehensive testing protocol for MRI neuroanatomical segmentation techniques: Evaluation of a novel lateral ventricle segmentation method
    Matthew J Kempton
    King s College London, Institute of Psychiatry, Department of Neuroimaging, UK
    Neuroimage 58:1051-9. 2011
    ..We also demonstrate that the novel segmentation algorithm and FreeSurfer are both effective in determining lateral ventricular volume and are well suited for multicentre and longitudinal MRI studies...
  3. doi Structural neuroimaging studies in major depressive disorder. Meta-analysis and comparison with bipolar disorder
    Matthew J Kempton
    Department of Neuroimaging, PO89, Institute of Psychiatry, King s College London, De Crespigny Park, London SE5 8AF, England
    Arch Gen Psychiatry 68:675-90. 2011
    ..Although differences in clinical characteristics exist between major depressive disorder (MDD) and bipolar disorder (BD), consistent structural brain abnormalities that distinguish the disorders have not been identified...
  4. doi Dehydration affects brain structure and function in healthy adolescents
    Matthew J Kempton
    Centre for Neuroimaging Sciences, Institute of Psychiatry, King s College London, London, SE5 8AF, United Kingdom
    Hum Brain Mapp 32:71-9. 2011
    ..Given the limited availability of brain metabolic resources, these findings suggest that prolonged states of reduced water intake may adversely impact executive functions such as planning and visuo-spatial processing...
  5. ncbi Effects of acute dehydration on brain morphology in healthy humans
    Matthew J Kempton
    Centre for Neuroimaging Sciences, Institute of Psychiatry, King s College London, London, United Kingdom
    Hum Brain Mapp 30:291-8. 2009
    ....
  6. doi The effects of gender and COMT Val158Met polymorphism on fearful facial affect recognition: a fMRI study
    Matthew J Kempton
    Section of Neurobiology of Psychosis, Institute of Psychiatry and NIHR Biomedical Research Centre for Mental Health, King s College London, UK
    Int J Neuropsychopharmacol 12:371-81. 2009
    ..The COMT Val108/158Met polymorphism impacts on gender-related patterns of activation in limbic and paralimbic regions but the functional significance of any oestrogen-related COMT inhibition appears modest...
  7. doi Molecular genetic gene-environment studies using candidate genes in schizophrenia: a systematic review
    Gemma Modinos
    Department of Psychosis Studies, Institute of Psychiatry, King s College London, United Kingdom Electronic address
    Schizophr Res 150:356-65. 2013
    ..Finally, we discuss the potential of future prospects, such as new studies that combine hypothesis-based molecular genetic candidate approaches with agnostic genome-wide association studies in determining schizophrenia risk. ..
  8. doi Dissociable brain structural changes associated with predisposition, resilience, and disease expression in bipolar disorder
    Matthew J Kempton
    Section of Neurobiology of Psychosis, Institute of Psychiatry, King s College London, London SE5 8AF, United Kingdom
    J Neurosci 29:10863-8. 2009
    ....
  9. doi Meta-analysis, database, and meta-regression of 98 structural imaging studies in bipolar disorder
    Matthew J Kempton
    Centre for Neuroimaging Sciences, Institute of Psychiatry, DeCrespigny Park, London SE5 8AF, England
    Arch Gen Psychiatry 65:1017-32. 2008
    ..Despite 25 years of structural imaging in bipolar disorder, brain regions affected in the disorder are ill defined...
  10. doi Progressive lateral ventricular enlargement in schizophrenia: a meta-analysis of longitudinal MRI studies
    Matthew J Kempton
    Centre for Neuroimaging Sciences, Institute of Psychiatry, King s College London, UK
    Schizophr Res 120:54-62. 2010
    ..To clarify this we conducted a meta-analysis of longitudinal studies measuring the lateral ventricles in patients with schizophrenia and a control group...
  11. doi Predicting psychosis: meta-analysis of transition outcomes in individuals at high clinical risk
    Paolo Fusar-Poli
    Department of Psychosis Studies, Institute of Psychiatry, King s College London, London, United Kingdom
    Arch Gen Psychiatry 69:220-9. 2012
    ..However, the risk of transition to psychosis varies between centers, and some recent work suggests that the risk of transition may be declining...
  12. pmc A voxel-based morphometry comparison of the 3.0T ADNI-1 and ADNI-2 volumetric MRI protocols
    Simon Brunton
    King s College London, Institute of Psychiatry, Department of Neuroimaging Sciences, London, UK NIHR Specialist Biomedical Research Centre for Mental Health at the South London and Maudsley NHS Foundation Trust and King s College, London, UK
    Int J Geriatr Psychiatry 30:531-8. 2015
    ..The aim of the current study was to investigate the compatibility of the 3.0 T ADNI-1 and ADNI-2 T1-weighted volumes using voxel-based morphometry (VBM)...
  13. doi Efficacy and safety of second-generation long-acting injections in schizophrenia: a meta-analysis of randomized-controlled trials
    Paolo Fusar-Poli
    Department of Psychosis Studies, Institute of Psychiatry, King s College London, London, UK
    Int Clin Psychopharmacol 28:57-66. 2013
    ..These data suggest that SGLAI lack an advantage in reducing psychotic symptoms over oral medications. Their potential effects on relapse prevention should be better addressed by future randomized-controlled trials...
  14. doi Serum brain-derived neurotrophic factor and cortical thickness are differently related in patients with schizophrenia and controls
    André Zugman
    Interdisciplinary Laboratory of Clinical Neurosciences LINC, Universidade Federal de Sao Paulo, Rua Pedro de Toledo, 669 3 andar fundos, Vila Clementino, Sao Paulo, SP, Brazil Department of Psychosis Study, Institute of Psychiatry, King s College London, 16 De Crespigny Park, SE5 8AF London, UK Electronic address
    Psychiatry Res 234:84-9. 2015
    ..BDNF levels and cortical thickness showed different patterns of correlation for patients and healthy controls in one cluster in the right hemisphere distributed across the supramarginal, postcentral, and inferior frontal cortices. ..
  15. doi Virtual reality in the psychological treatment for mental health problems: An systematic review of recent evidence
    Lucia R Valmaggia
    King s College London, Institute of Psychiatry, Psychology and Neuroscience, London, United Kingdom South London and Maudsley NHH Trust, London, United Kingdom Electronic address
    Psychiatry Res 236:189-95. 2016
    ..The reviewed studies confirm the effectiveness of VRT compared to treatment as usual, and show similar effectiveness when VRT is compared to conventional treatments. Current developments and future research are discussed. ..
  16. pmc Hippocampal hypertrophy and sleep apnea: a role for the ischemic preconditioning?
    Ivana Rosenzweig
    Department of Neuroimaging, Institute of Psychiatry, King s College, London, United Kingdom Danish Epilepsy Centre, Dianalund, Denmark
    PLoS ONE 8:e83173. 2013
    ..The role for the ischemia/hypoxia preconditioning in the neuropathology of OSA is herein indicated, with possible further reaching clinical implications. ..