Research Topics
| M J HurleySummaryAffiliation: King's College London Country: UK Publications
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Detail Information
Publications
Immunoautoradiographic analysis of NMDA receptor subunits and associated postsynaptic density proteins in the brain of dyskinetic MPTP-treated common marmosetsM J Hurley
Neurodegenerative Diseases Research Group, Pharmaceutical Sciences Division, School of Health and Life Sciences, King s College, London, SE1 1UL, UK
Eur J Neurosci 21:3240-50. 2005..These results suggest that l-DOPA treatment of MPTP-lesioned marmosets can affect glutamatergic systems and indicate that altered NMDA receptor function may relate to dyskinesia...
What has been learnt from study of dopamine receptors in Parkinson's disease?M J Hurley
Neurodegenerative Diseases Research Group, School of Biomedical and Health Sciences, King s College London, SE1 1UL, United Kingdom
Pharmacol Ther 111:715-28. 2006....
Striatal leucine-rich repeat kinase 2 mRNA is increased in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-lesioned common marmosets (Callithrix jacchus) with L-3, 4-dihydroxyphenylalanine methyl ester-induced dyskinesiaM J Hurley
Neurodegenerative Diseases Research Group, Pharmaceutical Sciences Research Division, School of Biomedical and Health Sciences, King s College, London SE1 1UL, UK
Eur J Neurosci 26:171-7. 2007..The correlation between striatal Lrrk2 mRNA levels in MPTP-treated common marmoset striatum and L-DOPA-induced dyskinesia indicates that LRRK2 may have a role in the molecular alterations that cause L-DOPA-induced dyskinesia...
Neural toxicity of retrovirusesM J Hurley
Department of Biochemistry, Imperial College of Science, Technology and Medicine, South Kensington, London, UK
Neurosci Lett 220:66-8. 1996..The results of this study indicate that retroviruses are not suitable vectors for the introduction of tyrosine hydroxylase into primary neuronal cultures...
Cultured human foetal cerebral cortex, transfected with tyrosine hydroxylase cDNA, as a source of neural transplant materialM J Hurley
Department of Biochemistry, Imperial College of Science, Technology and Medicine, London, United Kingdom
J Neural Transm 108:781-92. 2001..TH transfected foetal cerebral cortex cells may therefore be a useful alternative supply of tissue for use in neural transplants to treat Parkinson's disease...
Expression of cannabinoid CB1 receptor mRNA in basal ganglia of normal and parkinsonian human brainM J Hurley
Neurology Department, University of Miami School of Medicine, Miami, FL, USA
J Neural Transm 110:1279-88. 2003....
