M J Hurley
Affiliation: King's College London
- Immunoautoradiographic analysis of NMDA receptor subunits and associated postsynaptic density proteins in the brain of dyskinetic MPTP-treated common marmosetsM J Hurley
Neurodegenerative Diseases Research Group, Pharmaceutical Sciences Division, School of Health and Life Sciences, King s College, London, SE1 1UL, UK
Eur J Neurosci 21:3240-50. 2005..These results suggest that l-DOPA treatment of MPTP-lesioned marmosets can affect glutamatergic systems and indicate that altered NMDA receptor function may relate to dyskinesia...
- What has been learnt from study of dopamine receptors in Parkinson's disease?M J Hurley
Neurodegenerative Diseases Research Group, School of Biomedical and Health Sciences, King s College London, SE1 1UL, United Kingdom
Pharmacol Ther 111:715-28. 2006....
- Striatal leucine-rich repeat kinase 2 mRNA is increased in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-lesioned common marmosets (Callithrix jacchus) with L-3, 4-dihydroxyphenylalanine methyl ester-induced dyskinesiaM J Hurley
Neurodegenerative Diseases Research Group, Pharmaceutical Sciences Research Division, School of Biomedical and Health Sciences, King s College, London SE1 1UL, UK
Eur J Neurosci 26:171-7. 2007..The correlation between striatal Lrrk2 mRNA levels in MPTP-treated common marmoset striatum and L-DOPA-induced dyskinesia indicates that LRRK2 may have a role in the molecular alterations that cause L-DOPA-induced dyskinesia...
- Neural toxicity of retrovirusesM J Hurley
Department of Biochemistry, Imperial College of Science, Technology and Medicine, South Kensington, London, UK
Neurosci Lett 220:66-8. 1996..The results of this study indicate that retroviruses are not suitable vectors for the introduction of tyrosine hydroxylase into primary neuronal cultures...
- Cultured human foetal cerebral cortex, transfected with tyrosine hydroxylase cDNA, as a source of neural transplant materialM J Hurley
Department of Biochemistry, Imperial College of Science, Technology and Medicine, London, United Kingdom
J Neural Transm 108:781-92. 2001..TH transfected foetal cerebral cortex cells may therefore be a useful alternative supply of tissue for use in neural transplants to treat Parkinson's disease...
- Expression of cannabinoid CB1 receptor mRNA in basal ganglia of normal and parkinsonian human brainM J Hurley
Neurology Department, University of Miami School of Medicine, Miami, FL, USA
J Neural Transm 110:1279-88. 2003....