Research Topics
Species | Lars HolmbergSummaryAffiliation: King's College London Country: UK Publications
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Detail Information
Publications
Mammography casting-type calcification and risk of local recurrence in DCIS: analyses from a randomised studyL Holmberg
King s College London, Medical School, Division of Cancer Studies, London SE1 9RT, UK
Br J Cancer 108:812-9. 2013..We studied the association between mammographic calcifications and local recurrence in the ipsilateral breast...- Results from the Scandinavian Prostate Cancer Group Trial Number 4: a randomized controlled trial of radical prostatectomy versus watchful waitingLars Holmberg
Division of Cancer Studies, Guy s Hospital, King s College London, St Thomas Street, London, UK
J Natl Cancer Inst Monogr 2012:230-3. 2012..These questionnaire studies show an intricate pattern of symptoms evolving after surgery, hormonal treatments, signs of tumor progression, and also from natural aging. This article discusses some of the main findings of the SPCG-4 study... 
A comparison of prostate cancer survival in England, Norway and Sweden: a population-based studyL Holmberg
King s College London, Medical School, Division of Cancer Studies, Section of Cancer Epidemiology, SE1 9RT London, UK
Cancer Epidemiol 36:e7-12. 2012..The objective of the study was to compare patterns of survival 2001-2004 in prostate cancer patients from England, Norway and Sweden in relation to age and period of follow-up...- Absolute risk reductions for local recurrence after postoperative radiotherapy after sector resection for ductal carcinoma in situ of the breastLars Holmberg
Division of Cancer Studies, Thomas Guy House, 3rd Floor, King s College London, Guy s Campus, London SE1 9RT, United Kingdom
J Clin Oncol 26:1247-52. 2008..Evaluate the effects of radiotherapy after sector resection for ductal carcinoma in situ of the breast (DCIS) in patient groups as defined by age, size of the lesion, focality, completeness of excision and mode of detection... - Increased risk of recurrence after hormone replacement therapy in breast cancer survivorsLars Holmberg
Department of Surgical Sciences, Uppsala University, Uppsala, Sweden
J Natl Cancer Inst 100:475-82. 2008..We present results after extended follow-up... - National comparisons of lung cancer survival in England, Norway and Sweden 2001-2004: differences occur early in follow-upLars Holmberg
Division of Cancer Studies, King s College London, School of Medicine, Research Oncology, 3rd Floor Bermondsey Wing, Guy s Hospital, London SE1 9RT, UK
Thorax 65:436-41. 2010..Future improvements in lung cancer management may be seen early in follow-up... - Season of diagnosis and prognosis in breast and prostate cancerLars Holmberg
Regional Oncologic Center and Department of Surgical Sciences, Uppsala University, Uppsala, Sweden
Cancer Causes Control 20:663-70. 2009..Patients with breast or prostate cancer diagnosed during the summer season have been observed to have better survival. The extent to which this is due to biological and/or health care system related factors is unclear... - Differences in endpoints between the Swedish W-E (two county) trial of mammographic screening and the Swedish overview: methodological consequencesL Holmberg
Research Oncology, 3rd Floor Bermondsey Wing, Guy s Hospital, Divison of Cancer Studies, Guy s Campus, King s College London, SE1 9RT London, UK
J Med Screen 16:73-80. 2009.... - Radical prostatectomy versus watchful waiting in localized prostate cancer: the Scandinavian prostate cancer group-4 randomized trialAnna Bill-Axelson
Department of Urology, University Hospital, Uppsala, Sweden
J Natl Cancer Inst 100:1144-54. 2008..In 2005, we reported that radical prostatectomy improved prostate cancer survival compared with watchful waiting after a median of 8.2 years of follow-up. We now report results after 3 more years of follow-up... - Radical prostatectomy versus watchful waiting in early prostate cancerAnna Bill-Axelson
Department of Urology, University Hospital, Uppsala, Sweden
N Engl J Med 364:1708-17. 2011..In 2008, we reported that radical prostatectomy, as compared with watchful waiting, reduces the rate of death from prostate cancer. After an additional 3 years of follow-up, we now report estimated 15-year results... - Long-term quality-of-life outcomes after radical prostatectomy or watchful waiting: the Scandinavian Prostate Cancer Group-4 randomised trialEva Johansson
Department of Surgical Sciences, University Hospital of Uppsala, Uppsala, Sweden
Lancet Oncol 12:891-9. 2011..We report results for quality of life for men in the Scandinavian Prostate Cancer Group Study Number 4 (SPCG-4) after a median follow-up of more than 12 years... - Multiple events of fractures and cardiovascular and thromboembolic disease following prostate cancer diagnosis: results from the population-based PCBaSe SwedenMieke Van Hemelrijck
King s College London, School of Medicine, Division of Cancer Studies, Cancer Epidemiology Group, London, UK
Eur Urol 61:690-700. 2012..To date, adverse events of prostate cancer (PCa) treatment have only been studied as a single event, and little is known about the risk of subsequent adverse events... - Prognosis of metachronous contralateral breast cancer: importance of stage, age and interval time between the two diagnosesVoralak Vichapat
Cancer Epidemiology Group, Division of Cancer Studies, School of Medicine, King s College London, London, UK
Breast Cancer Res Treat 130:609-18. 2011..The occurrence of CBC implies a new surveillance and therapeutic situation... - Lipid profiles and risk of breast and ovarian cancer in the Swedish AMORIS studyJennifer C Melvin
1King s College London, School of Medicine, Division of Cancer Studies, Cancer Epidemiology Group, London, United Kingdom
Cancer Epidemiol Biomarkers Prev 21:1381-4. 2012..Perturbed lipid metabolism often accompanies obesity; we therefore ascertained the associations between lipid components and breast and ovarian cancer risk in a prospective cohort study... - Absolute and relative risk of cardiovascular disease in men with prostate cancer: results from the Population-Based PCBaSe SwedenMieke Van Hemelrijck
King s College London, London, United Kingdom
J Clin Oncol 28:3448-56. 2010..Cardiovascular disease (CVD) is a potential adverse effect of endocrine treatment (ET) for prostate cancer (PC). We investigated absolute and relative CVD risk in 76,600 patients with PC undergoing ET, curative treatment, or surveillance... - Risk of prostate cancer is not associated with levels of C-reactive protein and other commonly used markers of inflammationMieke Van Hemelrijck
King s College London, School of Medicine, Division of Cancer Studies, Cancer Epidemiology Group, London, United Kingdom
Int J Cancer 129:1485-92. 2011..This indicates need for international consensus on appropriate inflammatory markers in the context of cancer that may be practically applied in large studies... 
Radical prostatectomy versus watchful waiting in early prostate cancerAnna Bill-Axelson
Department of Urology, University Hospital, Uppsala, Sweden
N Engl J Med 352:1977-84. 2005..In 2002, we reported the initial results of a trial comparing radical prostatectomy with watchful waiting in the management of early prostate cancer. After three more years of follow-up, we report estimated 10-year results...- The interplay between lipid profiles, glucose, BMI and risk of kidney cancer in the Swedish AMORIS studyMieke Van Hemelrijck
King s College London, School of Medicine, Division of Cancer Studies, Cancer Epidemiology Group, London, UK
Int J Cancer 130:2118-28. 2012..This detailed analysis of lipid components only showed a consistent relation between TG levels and kidney cancer risk. Further mechanistic studies are required to assess links between lipid abnormalities and kidney cancer... - Gene copy number aberrations are associated with survival in histologic subgroups of non-small cell lung cancerPatrick Micke
Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden
J Thorac Oncol 6:1833-40. 2011..To maximize the chance to identify clinically relevant events, we applied a strategy involving two prognostically extreme patient groups... - Low levels of apolipoprotein A-I and HDL are associated with risk of prostate cancer in the Swedish AMORIS studyMieke Van Hemelrijck
King s College London, School of Medicine, Division of Cancer Studies, Cancer Epidemiology Group, Research Oncology, Bermondsey Wing, Guy s Hospital, London, SE1 9RT, UK
Cancer Causes Control 22:1011-9. 2011..Since several etiological pathways have been proposed for PCa and lipids, we aimed to study this in a large Swedish cohort with 1,469 primary prostate cancers... - Serum calcium and incident and fatal prostate cancer in the Swedish AMORIS studyMieke Van Hemelrijck
Cancer Epidemiology Group, Research Oncology, Division of Cancer Studies, School of Medicine, Guy s Hospital, King s College London, UK
Cancer Causes Control 23:1349-58. 2012..We studied the association between serum calcium and PCa while also accounting for levels of albumin, a protein to which calcium is bound... - Time, symptom burden, androgen deprivation, and self-assessed quality of life after radical prostatectomy or watchful waiting: the Randomized Scandinavian Prostate Cancer Group Study Number 4 (SPCG-4) clinical trialEva Johansson
Department of Urology, Uppsala University Hospital, Uppsala, Sweden
Eur Urol 55:422-30. 2009..Quality-of-life outcomes are important in the choice of treatment strategy for men with localized prostate cancer... - Tumor stage affects risk and prognosis of contralateral breast cancer: results from a large Swedish-population-based studyVoralak Vichapat
Division of Cancer Studies, King s College London, London, United
J Clin Oncol 30:3478-85. 2012..The number of breast cancer survivors at risk of developing contralateral breast cancer (CBC) is increasing. However, ambiguity remains regarding risk factors and prognosis for women with CBC... - Colorectal cancer survival in socioeconomic groups in England: variation is mainly in the short term after diagnosisHenrik Møller
King s College London, Thames Cancer Registry, 1st Floor Capital House, 42 Weston Street, London SE1 3QD, UK
Eur J Cancer 48:46-53. 2012..The objective of this study was to examine differences in cancer survival between socioeconomic groups in England, with particular attention to survival in the short term of follow-up... - Prostate cancer risk in the Swedish AMORIS study: the interplay among triglycerides, total cholesterol, and glucoseMieke Van Hemelrijck
King s College London, School of Medicine, Division of Cancer Studies, Cancer Epidemiology Unit, London, United Kingdom
Cancer 117:2086-95. 2011..In a cohort including 5112 prostate cancer (pCa) patients, the authors investigated associations among triglycerides (TG), total cholesterol (TC), and pCa while taking into account glucose... - Association between levels of C-reactive protein and leukocytes and cancer: three repeated measurements in the Swedish AMORIS studyMieke Van Hemelrijck
Cancer Epidemiology Group, Division of Cancer Studies, School of Medicine, King s College London, 3rd Floor, Bermondsey Wing, Guy s Hospital, London SE1 9RT, United Kingdom
Cancer Epidemiol Biomarkers Prev 20:428-37. 2011..To study levels of C-reactive protein (CRP) and leukocytes, as inflammatory markers, in the context of cancer risk... - Serum glucose and fructosamine in relation to risk of cancerWahyu Wulaningsih
King s College London, School of Medicine, Division of Cancer Studies, Cancer Epidemiology Group, London, United Kingdom
PLoS ONE 8:e54944. 2013..We used repeated measurements of glucose and fructosamine to get more insight into the association between the glucose metabolism and risk of cancer... - Primary cancers before and after prostate cancer diagnosisMieke Van Hemelrijck
Cancer Epidemiology Group, Division of Cancer Studies, School of Medicine, King s College London, London, United Kingdom
Cancer 118:6207-16. 2012..The occurrence of multiple cancers may indicate common etiology; and, although some studies have investigated the risk of second primary cancers after prostate cancer (PCa), there are no studies on cancers before PCa... - Gamma-glutamyl transferase and C-reactive protein as alternative markers of metabolic abnormalities and their associated comorbidites: a prospective cohort studyJennifer C Melvin
King s College London, School of Medicine, Division of Cancer Studies, Cancer Epidemiology Group London, UK Regional Oncologic Centre, Uppsala University Uppsala, Sweden
Int J Mol Epidemiol Genet 3:276-85. 2012..We assessed the link between GGT, CRP and common metabolic abnormalities, as well their link to related diseases, such as cancer and cardiovascular disease (CVD)... - Serum levels of selenium and smoking habits at age 50 influence long term prostate cancer risk; a 34 year ULSAM follow-upBirgitta Grundmark
Department of Surgical Sciences, Uppsala University, Uppsala, Sweden
BMC Cancer 11:431. 2011..We investigated the relation between s-Se, smoking and non-screening detected PrCa and explored if polymorphisms in two DNA repair genes: OGG1 and MnSOD, influenced any effect of s-Se... - Prognostic markers under watchful waiting and radical prostatectomyLars Holmberg
Regional Oncologic Center, University Hospital, Uppsala, Sweden
Hematol Oncol Clin North Am 20:845-55. 2006..Because overall prognostic information obtained by these parameters or by tumor stage was not provided in our publication, we now present these data in the two study arms separately... - Gamma-glutamyltransferase and risk of cancer in a cohort of 545,460 persons - the Swedish AMORIS studyMieke Van Hemelrijck
King s College London, School of Medicine, Division of Cancer Studies, Cancer Epidemiology Unit, London, UK
Eur J Cancer 47:2033-41. 2011..We aimed to study the association between GGT and cancer in a large Swedish cohort with 37,809 primary cancers... - Risk of thromboembolic diseases in men with prostate cancer: results from the population-based PCBaSe SwedenMieke Van Hemelrijck
King s College London, School of Medicine, Division of Cancer Studies, Cancer Epidemiology Group, London, UK
Lancet Oncol 11:450-8. 2010..We investigated the risk of thromboembolic disease in men with prostate cancer who were receiving endocrine treatment, curative treatment, or surveillance... - Breast cancer survival in England, Norway and Sweden: a population-based comparisonHenrik Møller
King s College London, Division of Cancer Studies, Thames Cancer Registry, London, United Kingdom
Int J Cancer 127:2630-8. 2010..Our findings emphasise the importance of awareness of symptoms and early detection as the main strategy to improve breast cancer survival in the United Kingdom... - Immunoglobulin E and cancer: a meta-analysis and a large Swedish cohort studyMieke Van Hemelrijck
Cancer Epidemiology Group, King s College London, London, UK
Cancer Causes Control 21:1657-67. 2010..Our findings suggest the need for prospective studies studying IgE and cancer. Measurements of IgE should be combined with other information, e.g., bio-banked samples containing other key immunological discriminators... - Social differences in breast cancer survival in relation to patient management within a National Health Care System (Sweden)Sonja Eaker
Department of Surgery, Uppsala University, Uppsala, Sweden
Int J Cancer 124:180-7. 2009.... - Biomarker discovery in non-small cell lung cancer: integrating gene expression profiling, meta-analysis, and tissue microarray validationJohan Botling
Departments of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden
Clin Cancer Res 19:194-204. 2013..So far, the value of these multigene signatures in clinical practice is unclear, and the biologic importance of individual genes is difficult to assess, as the published signatures virtually do not overlap... - Differences according to socioeconomic status in the management and mortality in men with high risk prostate cancerAnders Berglund
Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
Eur J Cancer 48:75-84. 2012..Outcomes for many cancer forms are associated with socioeconomic status (SES).We investigated if SES was associated with management and mortality in men with high risk prostate cancer... - Borderline ovarian tumors in Sweden 1960-2005: trends in incidence and age at diagnosis compared to ovarian cancerIngiridur Skirnisdottir
Department of Women s and Children s Health, Obstetrics and Gynecology, Uppsala University, Uppsala, Sweden
Int J Cancer 123:1897-901. 2008.... - Non-genital tract metastases to the ovaries presented as ovarian tumors in Sweden 1990-2003: occurrence, origin and survival compared to ovarian cancerIngiridur Skirnisdottir
Department of Women s and Children s Health, Obstetrics and Gynecology, Akademiska University Hospital, Uppsala, Sweden
Gynecol Oncol 105:166-71. 2007..Origin of metastases and time of detection in relation to surgery were recorded. Age at diagnosis, survival for ovarian metastasis compared to ovarian cancer and prognostic factors were evaluated... - A randomized trial comparing radical prostatectomy with watchful waiting in early prostate cancerLars Holmberg
Regional Oncologic Center, University Hospital, Uppsala, Sweden
N Engl J Med 347:781-9. 2002..41 to 0.96). CONCLUSIONS: In this randomized trial, radical prostatectomy significantly reduced disease-specific mortality, but there was no significant difference between surgery and watchful waiting in terms of overall survival... - Thromboembolic events following surgery for prostate cancerMieke Van Hemelrijck
King s College London, School of Medicine, Division of Cancer Studies, Cancer Epidemiology Group, London, UK
Eur Urol 63:354-63. 2013..Prostate cancer (PCa) and surgery are both associated with increased risk of thromboembolic diseases (TED)... - Serum Lipids and the Risk of Gastrointestinal Malignancies in the Swedish AMORIS StudyWahyu Wulaningsih
Cancer Epidemiology Group, Division of Cancer Studies, School of Medicine, King s College London, London, UK
J Cancer Epidemiol 2012:792034. 2012..Conclusion. The persistent link between TC and rectal cancer risk as well as between TG and oesophageal and colon cancer risk in normoglycaemic individuals may imply their substantiality in gastrointestinal carcinogenesis... - Experiences of randomization: interviews with patients and clinicians in the SPCG-IV trialAnna Bill-Axelson
Department of Urology, Uppsala University Hospital, Uppsala, Sweden
Scand J Urol Nephrol 42:358-63. 2008..This study investigated patients' and clinicians' experiences of randomization with the aim of facilitating trial participation in the future... - Birth outcome in women with previously treated breast cancer--a population-based cohort study from SwedenKristina Dalberg
Department of Surgery and the Regional Oncologic Centre, Uppsala University Hospital, Uppsala, Sweden
PLoS Med 3:e336. 2006..The aim of this study was to assess the risk of adverse birth outcomes in women previously treated for invasive breast cancer compared with the general population of mothers... - No increased prostate cancer incidence after negative transrectal ultrasound guided multiple biopsies in men with increased prostate specific antigen and/or abnormal digital rectal examinationAnna Bill-Axelson
Department of Urology, Uppsala University Hospital, Uppsala, Sweden
J Urol 170:1180-3. 2003..We investigated the incidence of prostate cancer after negative transrectal ultrasound (TRUS) guided multiple biopsies. Our secondary aim was to calculate the sensitivity of the extended protocol used... - Regional differences in treatment and outcome in non-small cell lung cancer: a population-based study (Sweden)Gunnar Myrdal
Department of Thoracic and Cardiovascular Surgery, Uppsala University Hospital, Uppsala, Sweden
Lung Cancer 63:16-22. 2009..Despite common guidelines there were marked differences in treatment activity between the counties. Treatment activity was associated with survival. Survival benefits may follow improvement in compliance to guidelines... - The occurrence of invasive cancers following a diagnosis of breast carcinoma in situD Robinson
Thames Cancer Registry, Division of Cancer Studies, King s College London, 1st Floor Capital House, 42 Weston Street, London SE1 3QD, UK
Br J Cancer 99:611-5. 2008..97 (95% ci 1.84-4.80)... - Serum lipid profiles and cancer risk in the context of obesity: four meta-analysesJennifer C Melvin
Cancer Epidemiology Group, Division of Cancer Studies, King s College London, School of Medicine, 3rd Floor, Bermondsey Wing, Guy s Hospital, London SE1 9RT, UK Regional Cancer Centre, Uppsala University Hospital, 751 85 Uppsala, Sweden
J Cancer Epidemiol 2013:823849. 2013..Future intervention studies involving lifestyle modification would provide insight into the potential biological role of lipid metabolism in tumorigenesis... - CD99 is a novel prognostic stromal marker in non-small cell lung cancerKarolina Edlund
Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden
Int J Cancer 131:2264-73. 2012..The results support the concept that stromal properties have an important impact on tumour progression... - Distribution of coronary artery stenosis after radiation for breast cancerGreger Nilsson
Uppsala University, University Hospital, SE 751 85 Uppsala, Sweden
J Clin Oncol 30:380-6. 2012..To study distribution of coronary artery stenosis among patients with breast cancer (BC) and to assess correlation between radiotherapy (RT) and location of stenosis... - Cyclin B is an immunohistochemical proliferation marker which can predict for breast cancer death in low-risk node negative breast cancerAnthoula Koliadi
Department of Oncology, Radiology and Clinical Immunology, Uppsala University, Uppsala, Sweden
Acta Oncol 49:816-20. 2010..Cyclin B is a proliferative marker easily assessed by immunohistochemistry. We wanted to examine cyclin B as a prognostic factor in low-risk breast cancer patients... - Neoadjuvant cisplatin-methotrexate chemotherapy for invasive bladder cancer -- Nordic cystectomy trial 2Amir Sherif
Department of Urology, Akademiska University Hospital, Uppsala, Sweden
Scand J Urol Nephrol 36:419-25. 2002..CONCLUSIONS: The chemotherapy regimen was well tolerated. Despite substantial downstaging no statistically significant survival benefit with the neoadjuvant therapy could be seen after 5 years of follow-up... - Risk factors for metachronous contralateral breast cancer suggest two aetiological pathwaysVoralak Vichapat
King s College London, School of Medicine, Division of Cancer Studies, Cancer Epidemiology Group, London SE1 9RT, UK
Eur J Cancer 47:1919-27. 2011..It may also imply that some CBCs are metastases from the first primary tumour, particularly in patients who present with recurrent disease before CBC... - The metabolic syndrome and the risk of prostate cancer under competing risks of death from other causesBirgitta Grundmark
Regional Oncologic Centre, Uppsala University Hospital, Uppsala, Sweden
Cancer Epidemiol Biomarkers Prev 19:2088-96. 2010..Using the National Cholesterol Education Program Adult Treatment panel III (NCEP) and International Diabetes Federation (IDF) definitions of the MetS, we investigated such associations taking competing risks of death into consideration... - Predictors of early death in female patients with breast cancer in the UK: a cohort studyCeilidh Stapelkamp
Bazian Ltd, 10 Fitzroy Square, London, UK
BMJ Open 1:e000247. 2011..The study identifies a group of women with a particularly poor prognosis for whom interventions aiming at early detection may be targeted... - Survival endpoints in colorectal cancer and the effect of second primary other cancer on disease free survivalHelgi Birgisson
Department of Surgical Sciences, Colorectal Surgery, Uppsala University, Uppsala, Sweden
BMC Cancer 11:438. 2011..The aim of this study was to compare different survival endpoints in patients with primary colorectal cancer (CRC) and to understand the effect of second primary other cancer on disease-free survival (DFS) calculations... - Season of cancer diagnosis exerts distinct effects upon short- and long-term survivalRahul Roychoudhuri
Thames Cancer Registry, Division of Cancer Studies, King s College London, Capital House, London, United Kingdom
Int J Cancer 124:2436-41. 2009..However, the distinct mortality reduction observed in the long term amongst those diagnosed in the autumn, especially amongst breast cancer patients, may indicate the presence of a seasonally variable protective mechanism... - Ductal carcinoma in situ of the breast: a new phenotype classification system and its relation to prognosisF Warnberg
Department of Surgery, University Hospital, Uppsala, Sweden
Breast Cancer Res Treat 73:215-21. 2002.... - Plasma vitamin D and mortality in older men: a community-based prospective cohort studyKarl Michaelsson
Department of Surgical Sciences and Uppsala Clinical Research Center, Uppsala University, Uppsala, Sweden
Am J Clin Nutr 92:841-8. 2010..Vitamin D status is known to be important for bone health but may also affect the development of several chronic diseases, including cancer and cardiovascular diseases, which are 2 major causes of death... - Quantification of normal cell fraction and copy number neutral LOH in clinical lung cancer samples using SNP array dataHanna Göransson
Department of Medical Sciences, Uppsala University, Uppsala, Sweden
PLoS ONE 4:e6057. 2009..Since tumor tissue invariably contains genetically normal stromal cells, this may lead to a failure to detect aberrations in the tumor cells... - Follow-up may not be beneficial after treatment of grade 1 breast cancerM Kontos
Breast Unit, Guy s Hospital, London, UK
Br J Surg 96:999-1004. 2009..This study investigated the risk of locoregional recurrence and contralateral breast cancer in women treated for grade 1 breast cancer... - Failure to detect early breast cancer using in vitro nuclear magnetic resonance spectroscopy of plasmaL Holmberg
Department of Surgery, University Hospital, Uppsala, Sweden
Br J Cancer 68:389-92. 1993..7 Hz). In vitro NMR spectroscopy in our hands was thus not a useful diagnostic tool in patients with early breast cancer... - Sector resection with and without radiotherapy in early breast cancer. Presentation of two ongoing prospective multicenter studies in Sweden. Uppsala/Orebro Breast Cancer Study GroupL Holmberg
Department of Surgery, University Hospital, Uppsala, Sweden
Acta Oncol 28:927-9. 1989..Overall 5% of the women in the conservatively treated group and 22% of the mastectomized women are still suffering substantial psychosocial disturbance after 13 months... - Trends in childhood and adolescent cancer survival in Sweden 1960 through 1984H O Adami
Cancer Epidemiology Unit, University Hospital, Uppsala, Sweden
Acta Oncol 31:1-10. 1992..Our data reflect the remarkable therapeutic improvements that have occurred for cancer in the young and indicate that these improvements have rapidly become available in Sweden... - Preoperative serum levels of follicle stimulating hormone (FSH) and prognosis in invasive breast cancerM Eskelinen
Regional Oncologic Center and Department of Surgery, University of Uppsala, Uppsala, Sweden
Eur J Surg Oncol 30:495-500. 2004..Today, FSH is not a clinical target for intervention or a clinically useful prognostic factor and the results of clinical studies up to date can only be used for motivation of further experimental laboratory research... - Prognosis in bilateral breast cancer. Effects of time interval between first and second primary tumoursL Holmberg
Department of Surgery, University Hospital, Uppsala, Sweden
Br J Cancer 58:191-4. 1988..The results indicate that the two tumours contribute independently to the patient's excess risk of dying and thus occur as two seemingly biologically unrelated events with respect to the tumour-host relationship and metastatic behaviour... - Age as a determinant of axillary node involvement in invasive breast cancerL Holmberg
Department of Surgery, University Hospital, Uppsala, Sweden
Acta Oncol 31:533-8. 1992..The findings indicate that the parallelism between the establishment of metastases in lymph nodes and at distant sites may vary with age. The prognostic value of nodal status may therefore depend on age at diagnosis... - Radiation to supraclavicular and internal mammary lymph nodes in breast cancer increases the risk of strokeG Nilsson
Department of Oncology, Radiology and Clinical Immunology, University Hospital, Uppsala, Sweden
Br J Cancer 100:811-6. 2009..Our finding of a target-specific increased risk of stroke and a dose-response relationship for daily fraction dose, indicate that there may be a causal link between RT to the IMC and SCL and risk of stroke... - Role of surgery in invasive breast cancerL Holmberg
Department of Surgery, University Hospital, Uppsala, Sweden
Acta Oncol 34:625-8. 1995.... - Five-node biopsy of the axilla: an alternative to axillary dissection of levels I-II in operable breast cancerJ Ahlgren
Department of Oncology, University Hospital, Uppsala, S-751 85, Sweden
Eur J Surg Oncol 28:97-102. 2002..Five-node biopsy is an alternative to axillary clearance and sentinel node biopsy in patients with operable breast cancer. Copyright Harcourt Publishers Limited... - Defining a high mortality risk group among women with primary breast cancerT Norden
Department of Surgery, University Hospital, Uppsala, Sweden
Br J Cancer 69:520-4. 1994..Women with no involved nodes and with three or four negative factors had a risk of dying from breast cancer similar to that of node-positive women with fewer than three... - Does immediate breast reconstruction using free flaps lead to delay in the administration of adjuvant chemotherapy for breast cancer?M Kontos
Breast Unit, Guy s Hospital, London, UK
Eur J Surg Oncol 36:745-9. 2010..However, these are complex surgical procedures with more complications and longer recovery time, which can potentially delay adjuvant treatment. Our aim is to investigate the impact of free flap IBR on the timing of adjuvant treatment... - Population based case-control study of sick leave in postmenopausal women before diagnosis of hyperparathyroidismE Lundgren
Department of Surgery, Uppsala University, S 751 85 Uppsala, Sweden
BMJ 317:848-51. 1998..To analyse sick leave in women at risk of primary hyperparathyroidism before its diagnosis... - Reduced utilisation of specialist care among elderly cancer patients: a randomised study of a primary healthcare interventionB Johansson
Department of Public Health and Caring Sciences, Uppsala University, S 751 83 Uppsala, Sweden
Eur J Cancer 37:2161-8. 2001..The conclusion is that older cancer patients' utilisation of specialist care may be reduced by intensified primary healthcare services... - Prognostic and predictive value of c-erbB-2 overexpression in primary breast cancer, alone and in combination with other prognostic markersS Sjogren
Department of Oncology, Akademiska sjukhuset, Uppsala University, Sweden
J Clin Oncol 16:462-9. 1998..To investigate the prognostic and predictive value of c-erbB-2 overexpression in breast cancer in relation to other prognostic markers... - Intensified primary cancer care: a randomized study of home care nurse contactsB Johansson
Department of Public Health and Caring Sciences, Uppsala University, Uppsala, Sweden
J Adv Nurs 30:1137-46. 1999.... - Pre-operative oestradiol levels - relation to survival in breast cancerL Holmberg
Department of Surgery, University Hospital, Uppsala, MA, S 751 85, Sweden
Eur J Surg Oncol 27:152-6. 2001..However, few studies have information on plasma levels of hormones pre-operatively... - Breast-conserving surgery without radiotherapyL Holmberg
Department of Surgery, University Hospital, Uppsala, Sweden
Acta Oncol 34:681-3. 1995..4) If the long-term--positive and negative--effects of radiotherapy were better quantified. Until we have new information, postoperative radiotherapy after breast conservation remains the standard...