Research Topics
Species | Claire M A HaworthSummaryAffiliation: King's College London Country: UK Publications
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Publications
No evidence for association between BMI and 10 candidate genes at ages 4, 7 and 10 in a large UK sample of twinsClaire M A Haworth
Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, UK
BMC Med Genet 9:12. 2008..The purpose of the present study was to test the developmental origins of some of these associations in a large longitudinal sample of children...- Bisulfite-based epityping on pooled genomic DNA provides an accurate estimate of average group DNA methylationSophia J Docherty
Social Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, De Crespigny Park, Denmark Hill, London, SE5 8AF, UK
Epigenetics Chromatin 2:3. 2009..Such an approach can be readily applied to the assessment of disease phenotypes reducing the time, cost and amount of DNA starting material required for large-scale epigenetic analyses... - Developmental origins of low mathematics performance and normal variation in twins from 7 to 9 yearsClaire M A Haworth
Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, De Crespigny Park, London, United Kingdom
Twin Res Hum Genet 10:106-17. 2007..We conclude that, despite the considerable differences in mathematics curricula from 7 to 9 years, the same genetic effects largely operate at the two ages... 
Generalist genes and high cognitive abilitiesClaire M A Haworth
Social, Genetic and Developmental Psychiatry Centre P080, Institute of Psychiatry, King s College London, London, UK
Behav Genet 39:437-45. 2009..However, a smaller proportion of the phenotypic intercorrelations appears to be explained by genetic influences for high abilities...- Increasing heritability of BMI and stronger associations with the FTO gene over childhoodClaire M A Haworth
Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, London, UK
Obesity (Silver Spring) 16:2663-8. 2008..01 at age 11. These findings suggest that expression of FTO may become stronger throughout childhood. Increases in heritability may also be due to children increasingly selecting environments correlated with their genetic propensities... - Sex differences and science: the etiology of science excellenceClaire M A Haworth
Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, UK
J Child Psychol Psychiatry 50:1113-20. 2009.... - Childhood obesity: genetic and environmental overlap with normal-range BMIClaire M A Haworth
Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, London, UK
Obesity (Silver Spring) 16:1585-90. 2008..To understand the overlap between the etiology of obesity and normal variation in BMI in children... 
Internet cognitive testing of large samples needed in genetic researchClaire M A Haworth
Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, London, United Kingdom
Twin Res Hum Genet 10:554-63. 2007..We conclude that Internet testing can be reliable and valid for collecting cognitive test data on large samples even for children as young as 10 years...- Quantitative genetics in the era of molecular genetics: learning abilities and disabilities as an exampleClaire M A Haworth
Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, United Kingdom
J Am Acad Child Adolesc Psychiatry 49:783-93. 2010..We focus on findings that go beyond merely estimating heritability. We use learning abilities and disabilities as examples... - The etiology of science performance: decreasing heritability and increasing importance of the shared environment from 9 to 12 years of ageClaire M A Haworth
SGDP Centre P080, Institute of Psychiatry, King s College London, De Crespigny Park, London SE5 8AF, United Kingdom
Child Dev 80:662-73. 2009..Understanding what these increasingly important shared environmental influences are could lead to interventions that encourage engagement in science throughout the lifespan... - Generalist genes and learning disabilities: a multivariate genetic analysis of low performance in reading, mathematics, language and general cognitive ability in a sample of 8000 12-year-old twinsClaire M A Haworth
Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, UK
J Child Psychol Psychiatry 50:1318-25. 2009..Here we assess whether this finding extends to language and general cognitive disabilities, as well as replicating the earlier finding for reading and mathematics in an older and larger sample... - Learning abilities and disabilities: generalist genes in early adolescenceOliver S P Davis
Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College, London, UK
Cogn Neuropsychiatry 14:312-31. 2009..A surprising finding emerging from multivariate quantitative genetic studies across diverse learning abilities is that most genetic influences are shared: they are "generalist", rather than "specialist"... - Socioeconomic status (SES) and children's intelligence (IQ): in a UK-representative sample SES moderates the environmental, not genetic, effect on IQKen B Hanscombe
Medical Research Council Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, London, United Kingdom
PLoS ONE 7:e30320. 2012..The evidence however is inconsistent. Other studies have reported an effect in the opposite direction (higher heritability in lower SES), or no moderation of the genetic effect on intelligence... - Added value measures in education show genetic as well as environmental influenceClaire M A Haworth
Social, Genetic and Developmental Psychiatry Centre, King s College London, London, United Kingdom
PLoS ONE 6:e16006. 2011..The pervasiveness of genetic influence in how and how much children learn is compatible with an active view of learning in which children create their own educational experiences in part on the basis of their genetic propensities... - Dramatic increase in heritability of cognitive development from early to middle childhood: an 8-year longitudinal study of 8,700 pairs of twinsOliver S P Davis
Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, De Crespigny Park, London SE5 8AF, United Kingdom
Psychol Sci 20:1301-8. 2009..57 and a shared environmental correlation of .65. These findings set constraints on how genetic and environmental variation affects the developing brain... - Chaotic homes and children's disruptive behavior: a longitudinal cross-lagged twin studySara R Jaffee
Institute of Psychiatry, Medical Research Council Social, Genetic and Developmental Psychiatry Centre, King s College London, England
Psychol Sci 23:643-50. 2012..However, genetic influences on disruptive behavior did not explain why household chaos was heritable... - A twin study of the genetics of high cognitive ability selected from 11,000 twin pairs in six studies from four countriesClaire M A Haworth
Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, London, UK
Behav Genet 39:359-70. 2009..41-0.60). Shared environmental influences were moderate (0.28, 0.19-0.37). We conclude that genetic variation contributes substantially to high g in Australia, the Netherlands, the United Kingdom and the United States... - Chaotic homes and school achievement: a twin studyKen B Hanscombe
King s College London, MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, London, UK
J Child Psychol Psychiatry 52:1212-20. 2011.... - Mathematical ability of 10-year-old boys and girls: genetic and environmental etiology of typical and low performanceYulia Kovas
Social, Genetic and Developmental Psychiatry Research Centre, Institute of Psychiatry, London, UK
J Learn Disabil 40:554-67. 2007..We conclude that low mathematical performance is the quantitative extreme of the same genetic and environmental factors responsible for variation throughout the distribution... - First genome-wide association study on anxiety-related behaviours in childhoodMaciej Trzaskowski
MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, De Crespigny Park, London, United Kingdom
PLoS ONE 8:e58676. 2013.... - Stable genetic influence on anxiety-related behaviours across middle childhoodMaciej Trzaskowski
King s College London, MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Box PO80, De Crespigny Park, London SE5 8AF, UK
J Abnorm Child Psychol 40:85-94. 2012..In contrast, though more varied, heterotypic continuity between some traits (i.e. the change from one type of anxiety-related behaviour into another over time) was mainly due to shared-environmental factors... - Genetic and environmental influences on children's food neophobiaLucy J Cooke
Cancer Research UK Health Behaviour Unit, Department of Epidemiology and Public Health, University College London, London, United Kingdom
Am J Clin Nutr 86:428-33. 2007..The design of effective interventions to improve children's diets would be facilitated by a better understanding of the determinants of neophobia... - Common disorders are quantitative traitsRobert Plomin
Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, London SE5 8AF, UK
Nat Rev Genet 10:872-8. 2009..Research that focuses on quantitative traits - including the low and high ends of normal distributions - could have far-reaching implications for the diagnosis, treatment and prevention of the problematic extremes of these traits... - A novel approach to genetic and environmental analysis of cross-lagged associations over time: the cross-lagged relationship between self-perceived abilities and school achievement is mediated by genes as well as the environmentYu L L Luo
National Key Laboratory of Cognitive Neuroscience and Learning, Beijing Normal University, China
Twin Res Hum Genet 13:426-36. 2010..We discuss implications of finding that genetic factors contribute to the cross-lag between self-perceived abilities at age 9 and school achievement at age 12... - Common DNA markers can account for more than half of the genetic influence on cognitive abilitiesRobert Plomin
1MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London
Psychol Sci 24:562-8. 2013..66 of the estimated heritability, reaffirming that cognitive abilities are heritable. Larger sample sizes alone will be sufficient to identify many of the genetic variants that influence cognitive abilities... - DNA methylation profiling using bisulfite-based epityping of pooled genomic DNASophia J Docherty
King s College London, MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, De Crespigny Park, London SE5 8AF, UK
Methods 52:255-8. 2010..This method generates accurate quantitative assessments of group DNA methylation averages, reducing the time, cost and amount of DNA starting material required for large-scale epigenetic investigation of disease phenotypes... - Twins Early Development Study (TEDS): A Genetically Sensitive Investigation of Cognitive and Behavioral Development From Childhood to Young AdulthoodClaire M A Haworth
Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, London, UK
Twin Res Hum Genet 16:117-25. 2013..TEDS represents an outstanding resource for investigating the developmental effects of genes and environments on complex quantitative traits from childhood to young adulthood and beyond... - The genetic and environmental origins of learning abilities and disabilities in the early school yearsYulia Kovas
Goldsmiths College, University of London, London, UK
Monogr Soc Res Child Dev 72:vii, 1-144. 2007..These conclusions have far-reaching implications for education and child development as well as for molecular genetics and neuroscience... - Obesity associated genetic variation in FTO is associated with diminished satietyJane Wardle
Health Behavior Research Centre, University College London, Gower Street, London WC1E 6BT, United Kingdom
J Clin Endocrinol Metab 93:3640-3. 2008..However, to date, it is not known whether the association between genetic variation in FTO and obesity is mediated through effects on energy intake or energy expenditure... - The genetic and environmental origins of learning abilities and disabilities in the early school yearsYulia Kovas
Goldsmiths College, University of London and SGDP Centre, Institute of Psychiatry
Monogr Soc Res Child Dev 72:vii, 1-144. 2007..These conclusions have far-reaching implications for education and child development as well as for molecular genetics and neuroscience...