A Greenough

Summary

Affiliation: King's College London
Country: UK

Publications

  1. ncbi request reprint Unilateral pulmonary agenesis
    Anne Greenough
    King s College London School of Medicine at Guy s, King s College and St Thomas Hospitals, Denmark Hill, London SE5 9PJ, UK
    J Perinat Med 34:80-1. 2006
  2. ncbi request reprint High frequency oscillation and liquid ventilation
    Anne Greenough
    Division of Asthma, Allergy and Lung Biology, King s College London School of Medicine at Guy s, King s College and St Thomas Hospitals, UK
    Paediatr Respir Rev 7:S186-8. 2006
  3. ncbi request reprint Emerging drugs for the prevention of bronchopulmonary dysplasia
    Anne Greenough
    Division of Asthma, Allergy and Lung Biology, King s College Hospital, Denmark Hill, London, SE5 9RS, UK
    Expert Opin Emerg Drugs 13:537-46. 2008
  4. pmc Neonatal ventilatory techniques - which are best for infants born at term?
    Olie Chowdhury
    Division of Asthma, Allergy and Lung Biology, MRC Asthma Centre for Allergic Mechanisms of Asthma, King s College London, London, United Kingdom
    Arch Med Sci 7:381-7. 2011
  5. ncbi request reprint Long-term respiratory consequences of premature birth at less than 32 weeks of gestation
    Anne Greenough
    Division of Asthma, Allergy and Lung Biology, The MRC and Asthma UK Centre in Allergic Mechanisms of Asthma King s College, London, UK Electronic address
    Early Hum Dev 89:S25-7. 2013
  6. ncbi request reprint Perinatal prevention of bronchopulmonary dysplasia
    Anne Greenough
    Division of Asthma, Allergy and Lung Biology, School of Medicine, King s College London, London, UK
    J Perinat Med 41:119-26. 2013
  7. doi request reprint How to ventilate term babies
    Anne Greenough
    Division of Asthma Allergy and Lung Biology, MRC and Asthma UK Centre in Allergic, Mechanisms of Asthma, King s College London, London SE5 9RS, United Kingdom
    Early Hum Dev 88:921-3. 2012
  8. doi request reprint Randomised weaning trial comparing assist control to pressure support ventilation
    Deena Shefali-Patel
    Division of Asthma, Allergy and Lung Biology, Kings College London, London, UK
    Arch Dis Child Fetal Neonatal Ed 97:F429-33. 2012
  9. doi request reprint The first five inflations during resuscitation of prematurely born infants
    Vadivelam Murthy
    Division of Asthma, Allergy and Lung Biology, MRC and Asthma UK Centre in Allergic, Mechanisms of Asthma, King s College London, UK
    Arch Dis Child Fetal Neonatal Ed 97:F249-53. 2012
  10. doi request reprint Volume-targeted ventilation in infants born at or near term
    Olie Chowdhury
    Division of Asthma, Allergy and Lung Biology, MRC Asthma UK Centre in Allergic Mechanisms of Asthma, King s College London, UK
    Arch Dis Child Fetal Neonatal Ed 97:F264-6. 2012

Collaborators

Detail Information

Publications139 found, 100 shown here

  1. ncbi request reprint Unilateral pulmonary agenesis
    Anne Greenough
    King s College London School of Medicine at Guy s, King s College and St Thomas Hospitals, Denmark Hill, London SE5 9PJ, UK
    J Perinat Med 34:80-1. 2006
  2. ncbi request reprint High frequency oscillation and liquid ventilation
    Anne Greenough
    Division of Asthma, Allergy and Lung Biology, King s College London School of Medicine at Guy s, King s College and St Thomas Hospitals, UK
    Paediatr Respir Rev 7:S186-8. 2006
    ..Clinical experience of liquid ventilation is limited, but improvements in oxygenation and lung function have been shown in short term studies...
  3. ncbi request reprint Emerging drugs for the prevention of bronchopulmonary dysplasia
    Anne Greenough
    Division of Asthma, Allergy and Lung Biology, King s College Hospital, Denmark Hill, London, SE5 9RS, UK
    Expert Opin Emerg Drugs 13:537-46. 2008
    ..Bronchopulmonary dysplasia (BPD) is a common adverse outcome of very premature birth and is associated with chronic respiratory morbidity...
  4. pmc Neonatal ventilatory techniques - which are best for infants born at term?
    Olie Chowdhury
    Division of Asthma, Allergy and Lung Biology, MRC Asthma Centre for Allergic Mechanisms of Asthma, King s College London, London, United Kingdom
    Arch Med Sci 7:381-7. 2011
    ..Randomised studies with long term outcomes are required to determine the optimum modes of ventilation in term born infants...
  5. ncbi request reprint Long-term respiratory consequences of premature birth at less than 32 weeks of gestation
    Anne Greenough
    Division of Asthma, Allergy and Lung Biology, The MRC and Asthma UK Centre in Allergic Mechanisms of Asthma King s College, London, UK Electronic address
    Early Hum Dev 89:S25-7. 2013
    ..Worryingly, lung function may deteriorate during the first year. Longitudinal studies are required to determine if there is catch up growth. ..
  6. ncbi request reprint Perinatal prevention of bronchopulmonary dysplasia
    Anne Greenough
    Division of Asthma, Allergy and Lung Biology, School of Medicine, King s College London, London, UK
    J Perinat Med 41:119-26. 2013
    ..In one major trial, it has been shown that BPD can be reduced without adverse effects by caffeine administration. Avoidance of high oxygen concentrations at resuscitation is also a promising approach to reduce BPD...
  7. doi request reprint How to ventilate term babies
    Anne Greenough
    Division of Asthma Allergy and Lung Biology, MRC and Asthma UK Centre in Allergic, Mechanisms of Asthma, King s College London, London SE5 9RS, United Kingdom
    Early Hum Dev 88:921-3. 2012
    ..RCTs with long term outcome are required to determine the optimum ventilatory modes in term born infants...
  8. doi request reprint Randomised weaning trial comparing assist control to pressure support ventilation
    Deena Shefali-Patel
    Division of Asthma, Allergy and Lung Biology, Kings College London, London, UK
    Arch Dis Child Fetal Neonatal Ed 97:F429-33. 2012
    ....
  9. doi request reprint The first five inflations during resuscitation of prematurely born infants
    Vadivelam Murthy
    Division of Asthma, Allergy and Lung Biology, MRC and Asthma UK Centre in Allergic, Mechanisms of Asthma, King s College London, UK
    Arch Dis Child Fetal Neonatal Ed 97:F249-53. 2012
    ..To study the first five inflations during the resuscitation of prematurely born infants and whether the infant's inspiratory efforts influenced the expired tidal volume...
  10. doi request reprint Volume-targeted ventilation in infants born at or near term
    Olie Chowdhury
    Division of Asthma, Allergy and Lung Biology, MRC Asthma UK Centre in Allergic Mechanisms of Asthma, King s College London, UK
    Arch Dis Child Fetal Neonatal Ed 97:F264-6. 2012
    ....
  11. ncbi request reprint Prediction of outcome from the chest radiograph appearance on day 7 of very prematurely born infants
    Anne Greenough
    Department of Child Health, Guy s, King s and St Thomas School of Medicine, King s College Hospital, SE5 9RS London, UK
    Eur J Pediatr 163:14-8. 2004
    ..In both studies, the areas under the receiver operator characteristic curves with regard to prediction of chronic lung disease were higher for the total chest radiograph score compared to those for readily available clinical data...
  12. pmc How has research in the past 5 years changed my clinical practice
    Anne Greenough
    Deparment of Child Health, 4th Floor Golden Jubilee Wing, King s College Hospital, London SE5 9RS, UK
    Arch Dis Child Fetal Neonatal Ed 92:F404-7. 2007
    ..Further research is required to identify the optimal respiratory support strategy, particularly for very immature infants...
  13. ncbi request reprint Nasal and lower airway levels of nitric oxide in prematurely born infants
    Olivia Williams
    Academic Department of Pediatrics, Guy s, King s, and St Thomas School of Medicine, King s College London, London, UK
    Early Hum Dev 72:67-73. 2003
    ..Thus, nasal NO would be predicted to be low in infants measured soon after birth and/or born very prematurely; this has implications for the measurement of exhaled NO and interpretation of the results obtained...
  14. ncbi request reprint Late respiratory outcomes after preterm birth
    Anne Greenough
    Division of Asthma, Allergy and Lung Biology, King s College London School of Medicine at Guy s, King s College and St Thomas Hospitals, UK
    Early Hum Dev 83:785-8. 2007
    ..Nowadays, severe BPD is uncommon, but those with "new" BPD may have abnormal antenatal lung growth, whether they achieve appropriate catch up lung growth needs careful investigation...
  15. ncbi request reprint Difficult extubation in low birthweight infants
    A Greenough
    Neonatal Intensive Care Centre, 4th Floor Golden Jubilee Wing, King s College Hospital, Denmark Hill, London SE5 9RS, UK
    Arch Dis Child Fetal Neonatal Ed 93:F242-5. 2008
    ..The above approaches are not mutually exclusive and those indicated by this review as appropriately evidence based should be considered by practitioners for current use to reduce difficult/unsuccessful extubation...
  16. pmc Preschool healthcare utilisation related to home oxygen status
    A Greenough
    King s College Hospital, London SE5 9RS, UK
    Arch Dis Child Fetal Neonatal Ed 91:F337-41. 2006
    ....
  17. doi request reprint School age outcome of hospitalisation with respiratory syncytial virus infection of prematurely born infants
    A Greenough
    Division of Asthma, King s College London, MRCAsthma Centre, London, UK
    Thorax 64:490-5. 2009
    ....
  18. ncbi request reprint The year in review
    Anne Greenough
    Division of Asthma, Allergy and Lung Biology, King s College London School of Medicine at Guy s, King s College and St Thomas Hospitals, London, UK
    Paediatr Respir Rev 10:2-5. 2009
    ..Others have examined the long-term outcome of viral infection in infancy. The above studies and others published in the last year will be discussed...
  19. ncbi request reprint Role of ventilation in RSV disease: CPAP, ventilation, HFO, ECMO
    Anne Greenough
    Division of Asthma, Allergy and Lung Biology, King s College London School of Medicine at Guy s, King s College and St Thomas Hospitals, London, UK
    Paediatr Respir Rev 10:26-8. 2009
    ..Current practice regarding ventilator support is largely based on clinical judgment and case reports. Multicentre randomised trials with long-term follow-ups are urgently required...
  20. ncbi request reprint What is new in ventilation strategies for the neonate?
    Anne Greenough
    Division of Asthma, Allergy and Lung Biology, King s College London, London, UK
    Eur J Pediatr 166:991-6. 2007
    ..More randomised trials with long-term outcomes are required to identify the optimal ventilation strategy(ies) for the neonate...
  21. ncbi request reprint Matching ventilatory support strategies to respiratory pathophysiology
    Anne Greenough
    Division of Asthma, Allergy and Lung Biology, King s College London, Children Nationwide Regional Neonatal Intensive Care Centre, 4th Floor, Golden Jubilee Wing, King s College Hospital, London SE5 9PJ, UK
    Clin Perinatol 34:35-53, v-vi. 2007
    ..Research is required to identify the optimum respiratory strategy for infants who have other respiratory disorders, particularly bronchopulmonary dysplasia...
  22. ncbi request reprint Optimal strategies for newborn ventilation--a synthesis of the evidence
    Anne Greenough
    Division of Asthma, Allergy and Lung Biology, King s College London, Children Nationwide Regional Neonatal Intensive Care Centre, 4th Floor, Golden Jubilee Wing, King s College Hospital, London, SE5 9PJ, UK
    Early Hum Dev 81:957-64. 2005
    ....
  23. ncbi request reprint Chronic manifestations of respiratory syncytial virus infection in premature infants
    Anne Greenough
    Division of Asthma, Allergy and Lung Biology, and National Intensive Care Center, 4th Floor Golden Jubilee Wing, Guy s, King s and St Thomas School of Medicine, King s College, London SE5 9RS, United Kingdom
    Pediatr Infect Dis J 24:S184-7, discussion S187-8. 2005
    ..Infants born prematurely are at increased risk of severe acute RSV infection; thus it would seem likely that such infants would be at increased risk of long term respiratory sequelae...
  24. ncbi request reprint Lung volumes in infants who had mild to moderate bronchopulmonary dysplasia
    Anne Greenough
    Division of Asthma, Allergy and Lung Biology, Guy s, King s and St Thomas School of Medicine, King s College London, London, UK
    Eur J Pediatr 164:583-6. 2005
    ..005), independently of postnatal age, birthweight and gestational age. It is concluded that the lower lung volumes of the infants who had had mild-moderate BPD support the hypothesis that new BPD is associated with poor alveolarisation...
  25. ncbi request reprint Pulmonary hypertension in the newborn
    Anne Greenough
    Division of Asthma, Allergy and Lung Biology, Department of Child Health, Guy s, King s, and St Thomas s School of Medicine, King s College London, UK
    Paediatr Respir Rev 6:111-6. 2005
    ....
  26. pmc Risk factors for respiratory morbidity in infancy after very premature birth
    A Greenough
    Department of Child Health, 4th Floor Golden Jubilee Wing, King s College Hospital, Bessemer Road, London SE5 9RS, UK
    Arch Dis Child Fetal Neonatal Ed 90:F320-3. 2005
    ..To determine the occurrence of respiratory morbidity during infancy after very premature birth and to identify risk factors...
  27. ncbi request reprint Bronchopulmonary dysplasia--long term follow up
    Anne Greenough
    Division of Asthma, Allergy and Lung Biology, King s College London School of Medicine at Guy s, King s College and St Thomas Hospitals, UK
    Paediatr Respir Rev 7:S189-91. 2006
    ..Troublesome respiratory symptoms are common in children who had BPD, as are lung function abnormalities even in adolescents and young adults...
  28. ncbi request reprint Prevention and management of meconium aspiration syndrome--assessment of evidence based practice
    Anne Greenough
    Division of Asthma, Allergy and Lung Biology, Department of Child Health, 4th Floor Golden Jubilee Wing, King s College Hospital, Denmark Hill, SE5 9RS London, UK
    Eur J Pediatr 164:329-30. 2005
  29. ncbi request reprint Corticosteroids in infant chronic lung disease
    C May
    Guy s, King s and St Thomas School of Medicine, King s College London
    Monaldi Arch Chest Dis 61:162-6. 2004
    ..Further research is required to accurately identify infants at highest risk of developing CLD, the corticosteroid dosage associated with a positive risk: benefit ratio and preferably a safer and more effective alternative therapy...
  30. ncbi request reprint Effect of in utero growth retardation on lung function at follow-up of prematurely born infants
    A Greenough
    Dept of Child Health, Division of Asthma, Allergy and Lung Biology, Guy s, King s and St Thomas School of Medicine, London, UK
    Eur Respir J 24:731-3. 2004
    ..In conclusion, these results suggest that prematurely born infants who have suffered intra-uterine growth retardation may be at increased risk of impaired lung function at follow-up...
  31. ncbi request reprint High versus restricted use of home oxygen therapy, health care utilisation and the cost of care in chronic lung disease infants
    Anne Greenough
    Department of Child Health, King s College Hospital, SE5 9RS London, UK
    Eur J Pediatr 163:292-6. 2004
    ..001). The post-discharge costs were similar in the two types of centre, but the neonatal costs (P < 0.0001) and total cost of care per infant over the first 2 years (P < 0.0001) were lower in the high use centres...
  32. ncbi request reprint Radiological outcome of very prematurely born infants randomised to high frequency oscillatory or conventional ventilation
    Anne Greenough
    Children Nationwide Regional Neonatal Intensive Care Centre, King s College Hospital, 4th floor Ruskin Wing, SE5 9RS, London, UK
    Eur J Pediatr 163:671-4. 2004
    ..2 HFOV versus 3.5 CMV, 95%CI for difference -0.66 to 0.06, P=0.11 at 28 days and mean scores 3.5 HFOV versus 3.6 CMV, 95% for difference -0.49 to 0.29, P=0.61 at 36 weeks PMA)...
  33. pmc Health care utilisation of prematurely born, preschool children related to hospitalisation for RSV infection
    A Greenough
    Dept of Child Health, King s College Hospital, London SE5 9RS, UK
    Arch Dis Child 89:673-8. 2004
    ..In prematurely born infants with chronic lung disease (CLD), RSV hospitalisation is associated with increased health service utilisation and costs in the first two years after birth...
  34. doi request reprint Prenatal factors in the development of chronic lung disease
    Anne Greenough
    Division of Asthma, Allergy and Lung Biology, King s College London School of Medicine, Denmark Hill, London, UK
    Semin Fetal Neonatal Med 14:339-44. 2009
    ..Antenatal interventions directed at improving lung growth are available, but require testing inappropriately designed trials with pulmonary function at follow-up as an outcome...
  35. doi request reprint Respiratory morbidity, healthcare utilisation and cost of care at school age related to home oxygen status
    Anne Greenough
    Division of Asthma, Allergy and Lung Biology, MRC Asthma Centre for Allergic Mechanisms of Asthma, King s College London, London, UK
    Eur J Pediatr 170:969-75. 2011
    ..Whether such children require greater follow, in the absence of excess respiratory morbidity, merits investigation...
  36. ncbi request reprint Measuring respiratory outcome
    A Greenough
    Dept of Child Health, King s College Hospital, London, UK
    Semin Neonatol 5:119-26. 2000
    ..These problems are detected even in adolescents who were chronically oxygen dependent after premature birth. Further research to identify effective preventative strategies is urgently required...
  37. ncbi request reprint Expanded use of surfactant replacement therapy
    A Greenough
    Department of Child Health, King s College Hospital, London, UK
    Eur J Pediatr 159:635-40. 2000
    ..Those data are very promising and should encourage studies to identify the optimum type of surfactant, dosage regimen and administration method...
  38. ncbi request reprint Inhaled nitric oxide in the neonatal period
    A Greenough
    Division of Women s and Children s Health, Guy s, King s and St Thomas School of Medicine, King s College Hospital, London SE5 9RS, UK
    Expert Opin Investig Drugs 9:1601-9. 2000
    ..Careful patient selection should be undertaken, avoiding those at high risk of haemorrhagic complications. Longer term follow-up studies are required to determine the real risk:benefit ratio of inhaled nitric oxide treatment...
  39. ncbi request reprint Respiratory syncytial virus prevention: past and present strategies
    A Greenough
    Guy s, King s and St Thomas School of Medicine, King s College Hospital, London SE5 9RS, UK
    Expert Opin Pharmacother 1:1195-201. 2000
    ..Studies have suggested it is essential to carefully select patients for immunoprophylaxis, if its use is to be cost-effective...
  40. pmc Home oxygen status and rehospitalisation and primary care requirements of infants with chronic lung disease
    A Greenough
    Department of Child Health, King s College Hospital, London, UK
    Arch Dis Child 86:40-3. 2002
    ....
  41. pmc Treatment requirements of infants with rhesus isoimmunisation within a geographically defined area
    A Greenough
    Department of Child Health, King s College Hospital, London, UK
    Arch Dis Child Fetal Neonatal Ed 87:F202-3. 2002
    ..To provide population based data on the treatment requirements of infants with rhesus isoimmunisation...
  42. ncbi request reprint Routine daily chest radiographs in ventilated, very low birth weight infants
    A Greenough
    Children Nationwide Regional Neonatal Intensive Care Centre, King s College Hospital, London, UK
    Eur J Pediatr 160:147-9. 2001
    ....
  43. pmc Health care utilisation of infants with chronic lung disease, related to hospitalisation for RSV infection
    A Greenough
    Dept of Child Health, King s College Hospital, London SE5 9RS, UK
    Arch Dis Child 85:463-8. 2001
    ..To compare the use of health care resources and associated costs between infants with chronic lung disease (CLD) who had or had not an admission with a proven respiratory syncytial virus (RSV) infection...
  44. ncbi request reprint Recent advances in the management and prophylaxis of respiratory syncytial virus infection
    A Greenough
    Department of Child Health, Guy s, King s and St Thomas School of Medicine, King s College Hospital, London, UK
    Acta Paediatr Suppl 90:11-4. 2001
    ..Immunoprophylaxis should be reserved for infants at highest risk of severe respiratory syncytial virus infection, if this strategy is to be used most cost-effectively...
  45. ncbi request reprint The role of immunoglobulins in neonatal Rhesus haemolytic disease
    A Greenough
    Children Nationwide Regional Neonatal Intensive Care Centre, Division of Women s and Children s Health, Guy s, King s and St Thomas School of Medicine, King s College London, England
    BioDrugs 15:533-41. 2001
    ..There are, however, potential risks of immunoglobulin administration, including haemolysis due to the presence of anti-A or anti-B antibodies, allergy and the transmission of disease...
  46. ncbi request reprint Respiratory support techniques for prematurely born infants: new advances and perspectives
    A Greenough
    Academic Department of Paediatrics, Guy s, King s and St Thomas Medical School, Children Nationwide Regional Neonatal Intensive Care Centre, 4th Floor, Ruskin Wing, King s College Hospital, London SE5 9RS, U K
    Acta Paediatr Taiwan 42:201-6. 2001
    ....
  47. ncbi request reprint [New trends in mechanical ventilation]
    Anne Greenough
    Children Nationwide Professor of Neonatology and Clinical Respiratory Physiology, Head of the Academic Department of Paediatrics, Guy s, King s and St Thomas Medical School, King s College Hospital, London, United Kingdom
    An Esp Pediatr 56:121-6. 2002
    ..Ventilatory strategies should only be introduced into routine clinical practice if proven efficacious and without long term adverse effects in appropriately sized studies...
  48. ncbi request reprint Rhesus disease: postnatal management and outcome
    A Greenough
    Children Nationwide Regional Neonatal Intensive Care Centre, King s College Hospital, London, UK
    Eur J Pediatr 158:689-93. 1999
    ..Multicentre collaboration is required to test strategies to improve the management of affected individuals further and to provide meaningful data on their prognosis...
  49. pmc Update on modalities of mechanical ventilators
    A Greenough
    Children Nationwide Regional Neonatal Intensive Care, College Hospital, London SE5 9RS, UK
    Arch Dis Child Fetal Neonatal Ed 87:F3-6. 2002
    ..Ventilation modes should only be introduced into routine clinical practice when proved efficacious in appropriately designed studies and no adverse outcomes identified by long term follow up...
  50. ncbi request reprint Use and misuse of albumin infusions in neonatal care
    A Greenough
    Department of Child Health, King s College Hospital, London, UK
    Eur J Pediatr 157:699-702. 1998
    ..The role of an albumin infusion in "treating" metabolic acidosis needs further evaluation, but the practice of giving albumin to correct "asymptomatic" hypoalbuminaemia or at resuscitation should be discouraged...
  51. ncbi request reprint Update on patient-triggered ventilation
    A Greenough
    Department of Child Health, Guy s King s and St Thomas School of Medicine, King s College Hospital, London, United Kingdom
    Clin Perinatol 28:533-46. 2001
    ..Essential, before any such trial, is identification of optimum method of PTV delivery, which may be disease specific...
  52. ncbi request reprint Colloid infusion in the perinatal period and abnormal neurodevelopmental outcome in very low birth weight infants
    Anne Greenough
    Department of Child Health, Guy s, King s and St Thomas School of Medicine, King s College Hospital, London SE5 9RS, United Kingdom
    Eur J Pediatr 161:319-23. 2002
    ..Regression analysis demonstrated that only colloid infusion related significantly to abnormal neurodevelopmental outcome independent of other variables...
  53. ncbi request reprint Respiratory syncytial virus infection: clinical features, management, and prophylaxis
    Anne Greenough
    Department of Paediatrics, Guy s, King s and St Thomas School of Medicine, King s College, London, UK
    Curr Opin Pulm Med 8:214-7. 2002
    ..Nevertheless, the cost of prophylaxis, unless only given to very high-risk infants, exceeds savings made in reducing admissions...
  54. doi request reprint Respiratory outcomes in early childhood following antenatal vitamin C and E supplementation
    Anne Greenough
    Division of Asthma, Allergy and Lung Biology, MRC and Asthma UK Centre in Allergic Mechanisms of Asthma, King s College London, London, UK
    Thorax 65:998-1003. 2010
    ....
  55. ncbi request reprint Prophylaxis of chronic lung disease after premature birth
    A Greenough
    Division of Women s and Children s Health, Guy s King s and St Thomas School of Medicine, King s College Hospital, London SE5 9RS, UK
    Monaldi Arch Chest Dis 56:413-7. 2001
    ....
  56. ncbi request reprint Prediction of prolonged ventilator dependence in children by respiratory function measurements
    A Greenough
    Department of Child Health, King s College Hospital, London, UK
    Physiol Meas 20:201-5. 1999
    ..We therefore conclude that respiratory function measurements have a role in identifying children who would benefit from strategies to prevent prolonged ventilator dependence...
  57. pmc Frequent wheeze at follow up of very preterm infants: which factors are predictive?
    M Thomas
    Department of Child Health, King s College Hospital, London, UK
    Arch Dis Child Fetal Neonatal Ed 88:F329-32. 2003
    ..To determine if chest radiograph appearance at 28 days or 36 weeks postmenstrual age (PMA) can predict recurrent wheeze or cough at follow up in prematurely born infants more effectively than readily available clinical data...
  58. pmc Exhaled nitric oxide in chronically ventilated preterm infants
    O Williams
    Children Nationwide Regional Neonatal Intensive Care Centre, 4th floor Ruskin Wing, King s College Hospital, London SE5 9RS, UK
    Arch Dis Child Fetal Neonatal Ed 89:F88-9. 2004
    ..The eNO levels fell from a mean of 6.5 (SD 3.4) to 4.2 (SD 2.6) parts per billion (p = 0.031) and the mean supplementary oxygen levels from 62% to 45% (p = 0.0078)...
  59. doi request reprint Antenatal and postnatal management of congenital cystic adenomatoid malformation
    S Kotecha
    Department of Child Health, School of Medicine, Cardiff University, Cardiff, CF14 4XN, United Kingdom
    Paediatr Respir Rev 13:162-70; quiz 170-1. 2012
    ..Due to the potential of malignant transformation, children should have long term follow up. There is an urgent need to delineate the natural history of antenatally detected CCAMs to guide future management...
  60. ncbi request reprint Sleeping position, oxygenation and lung function in prematurely born infants studied post term
    T Saiki
    MRC Asthma Centre, Division of Asthma, Allergy and Lung Biology, King s College Hospital, King s College London, Denmark Hill, London, UK
    Arch Dis Child Fetal Neonatal Ed 94:F133-7. 2009
    ....
  61. ncbi request reprint Lung volume and the response to high volume strategy, high frequency oscillation
    G Dimitriou
    Department of Child Health, Guy s, King s and St Thomas Medical School, King s College London, London SE5 9PJ, UK
    Acta Paediatr 93:613-7. 2004
    ..Mean airway pressure (MAP) is then elevated, the aim being to open up atelectatic lungs and hence improve gas exchange...
  62. doi request reprint Relation of exhaled nitric oxide levels to development of bronchopulmonary dysplasia
    C May
    Division of Asthma, Allergy and Lung Biology, King s College Hospital, Denmark Hill, London SE5 9RS, UK
    Arch Dis Child Fetal Neonatal Ed 94:F205-9. 2009
    ..To test the hypothesis that exhaled nitric oxide levels on day 28 and changes in exhaled nitric oxide levels in the neonatal period would differ according to whether infants developed bronchopulmonary dysplasia (BPD) and its severity...
  63. ncbi request reprint Comparison of respiratory function and fluid balance in very low birthweight infants given artificial or natural surfactant or no surfactant treatment
    V Kavvadia
    Children Nationwide Regional Neonatal Intensive Care Centre at King s College Hospital, London, UK
    J Perinat Med 26:469-74. 1998
    ..These results do not support the hypothesis that differences in fluid balance explain differences in the lung function improvement rate following natural and artificial surfactant...
  64. pmc Respiratory function of very prematurely born infants at follow up: influence of sex
    M R Thomas
    Department of Child Health, 4th Floor Golden Jubilee Wing, King s College Hospital, London SE5 9RS, UK
    Arch Dis Child Fetal Neonatal Ed 91:F197-201. 2006
    ..To test the hypothesis that male compared with female prematurely born infants would have worse lung function at follow up...
  65. doi request reprint Diaphragm electromyogram in infants with abdominal wall defects and congenital diaphragmatic hernia
    Z Kassim
    Division of Asthma, Allergy and Lung Biology, King s College, London, UK
    Eur Respir J 37:143-9. 2011
    ..Oesophageal EMG and magnetic stimulation of the phrenic nerves can be useful to assess phrenic nerve function in infants. Reduced phrenic nerve conduction accompanies the reduced diaphragm force production observed in infants with CDH...
  66. pmc Plethysmograph and interrupter resistance measurements in prematurely born young children
    M R Thomas
    Department of Child Health, 4th Floor Golden Jubilee Wing, King s College Hospital, Bessemer Road, London SE5 9RS, UK
    Arch Dis Child Fetal Neonatal Ed 91:F193-6. 2006
    ..Airways obstruction in premature infants is often assessed by plethysmography, which requires sedation. The interrupter (Rint) technique does not require sedation, but has rarely been examined in children under 2 years of age...
  67. ncbi request reprint Peak expiratory flow in Afro-Caribbean children with and without sickle cell anaemia
    K P Sylvester
    Division of Asthma, Allergy and Lung Biology, MRC Asthma Centre, King s College London, UK
    Acta Paediatr 96:1308-10. 2007
    ....
  68. doi request reprint Three-dimensional ultrasound fetal lung volumes and infant respiratory outcome: a prospective observational study
    M Prendergast
    Division of Asthma, Allergy and Lung Biology, MRC and Asthma UK Centre in Allergic Mechanisms of Asthma, King s College London, London, UK
    BJOG 118:608-14. 2011
    ....
  69. pmc Diminished lung function, RSV infection, and respiratory morbidity in prematurely born infants
    S Broughton
    Division of Asthma, Allergy and Lung Biology, Guy s, King s and St Thomas School of Medicine, King s College London, UK
    Arch Dis Child 91:26-30. 2006
    ..Diminished lung function appears to be a risk factor for respiratory syncytial virus (RSV) infection/bronchiolitis in term born infants...
  70. pmc Growth effects of systemic versus inhaled steroids in chronic lung disease
    R M Nicholl
    Children Nationwide Regional Neonatal Intensive Care Centre, King s College Hospital, London, UK
    Arch Dis Child Fetal Neonatal Ed 87:F59-61. 2002
    ..To compare the effects of inhaled and systemic steroids on growth in very low birthweight (VLBW) infants with chronic lung disease (CLD)...
  71. ncbi request reprint A scoring system to predict chronic oxygen dependency
    Caroline May
    Division of Asthma, Allergy and Lung Biology, King s College London School of Medicine, Guy s, King s College and St Thomas Hospitals, London, UK
    Eur J Pediatr 166:235-40. 2007
    ..Our aim was to determine if a simple score based on respiratory support requirements predicted COD development...
  72. ncbi request reprint Evaluation of triggering systems for patient triggered ventilation for neonates ventilator-dependent beyond 10 days of age
    V Chan
    Department of Child Health, King s College Hospital, London, United Kingdom
    Eur J Pediatr 151:842-5. 1992
    ..01). We conclude that the airway pressure trigger has a superior performance compared to the MR10 respiration monitor trigger in infants who are ventilator-dependent beyond 10 days of age...
  73. pmc Prospective study of healthcare utilisation and respiratory morbidity due to RSV infection in prematurely born infants
    S Broughton
    Division of Asthma, Allergy and Lung Biology, Guy s, King s and St Thomas Medical School, King s College London, and Department of Child Health, King s College Hospital, UK
    Thorax 60:1039-44. 2005
    ....
  74. ncbi request reprint Effect of posture on oxygenation, lung volume, and respiratory mechanics in premature infants studied before discharge
    Ravindra Yeshwant Bhat
    Children Nationwide Regional Neonatal Intensive Care Centre, Kings College Hospital, London, United Kingdom
    Pediatrics 112:29-32. 2003
    ....
  75. ncbi request reprint Lung function and exhaled nitric oxide levels in infants developing chronic lung disease
    Olivia Williams
    Department of Child Health, Division of Asthma, Allergy and Lung Biology, Guy s, King s, King s College, London, United Kingdom
    Pediatr Pulmonol 42:107-13. 2007
    ..94 and 0.91, respectively. Early lung function test results, but not eNO levels, are useful in predicting CLD development, but are not significantly better than birthweight...
  76. ncbi request reprint Effectiveness of drug therapies to treat or prevent respiratory syncytial virus infection-related morbidity
    Simon Broughton
    Department of Child Health, Guy s King s and St Thomas Medical School, 4th Floor Golden Jubilee Wing, King s College Hospital, London SE5 9RS, UK
    Expert Opin Pharmacother 4:1801-8. 2003
    ..In the prevention of chronic respiratory morbidity following RSV infection, however, studies are needed to determine whether immunoprophylaxis will have a useful role and to identify which drug treatment will be most cost-effective...
  77. pmc Sleeping position, oxygen saturation and lung volume in convalescent, prematurely born infants
    Zainab Kassim
    Children Nationwide Regional Neonatal Intensive Care Centre, 4th Floor, Golden Jubilee Wing, King s College Hospital, London SE5 9PJ, UK
    Arch Dis Child Fetal Neonatal Ed 92:F347-50. 2007
    ..To determine whether the effects of sleeping position on lung volume and oxygenation are influenced by postmenstrual age (PMA) and oxygen dependency in convalescent prematurely born infants...
  78. ncbi request reprint Survey of neonatal respiratory support strategies
    Atul Sharma
    King s College London, MRC Asthma Centre, Division of Asthma, Allergy and Lung Biology, London, UK
    Acta Paediatr 96:1115-7. 2007
    ..To survey current practice regarding neonatal respiratory support strategies to determine whether it reflected evidence from randomised trials...
  79. ncbi request reprint Maternal drug use and length of neonatal unit stay
    K Johnson
    Children Nationwide Regional Neonatal Intensive Care Centre, King s College Hospital, London, UK
    Addiction 98:785-9. 2003
    ....
  80. ncbi request reprint Impact of acute chest syndrome on lung function of children with sickle cell disease
    Karl P Sylvester
    Departments of Child Health, Health and Life Sciences, and Haematological Medicine, King s College London School of Medicine at Guy s, King s College, and St Thomas Hospitals, London, United Kingdom
    J Pediatr 149:17-22. 2006
    ..To test the hypothesis that children with sickle cell disease (SCD) who experienced an acute chest syndrome (ACS) hospitalization episode would have worse lung function than children with SCD without ACS episodes...
  81. ncbi request reprint Definitive surgical management of antenatally diagnosed exomphalos
    Ashok Rijhwani
    Department of Paediatric Surgery, Kings College Hospital, SE5 9RS London, UK
    J Pediatr Surg 40:516-22. 2005
    ..The aim of the study was to ascertain the outcome of all infants with an antenatally diagnosed exomphalos treated recently at our institution using a policy of aggressive abdominal wall closure...
  82. ncbi request reprint Post-natal corticosteroid use
    Olivia Williams
    Children Nationwide Regional Neonatal Intensive Care Unit, Department of Child Health, Kings College Hospital, SE5 9RS London, UK
    Eur J Pediatr 162:613-5. 2003
    ..1 mg/kg per day or less. The majority (77%) prescribed corticosteroids only to ventilator-dependent infants, others also gave corticosteroids to chronically continuous positive airway pressure- or oxygen-dependent infants...
  83. ncbi request reprint High-frequency oscillatory ventilation for the prevention of chronic lung disease of prematurity
    Alice H Johnson
    Department of Child Health, St George s Hospital Medical School, London, United Kingdom
    N Engl J Med 347:633-42. 2002
    ..We conducted a multicenter trial to determine whether early intervention with high-frequency oscillatory ventilation reduced mortality and the incidence of chronic lung disease among newborns with a gestational age of 28 weeks or less...
  84. ncbi request reprint An illness severity score and neonatal mortality in retrieved neonates
    Simon J Broughton
    Department of Child Health, Guy s King s and St Thomas School of Medicine, King s College Hospital, 4th Floor Golden Jubilee Wing, Bessemer Road, SE5 9RS London, UK
    Eur J Pediatr 163:385-9. 2004
    ..56) or birth weight (0.52). The mean MCRIB score fell progressively from the time of first call to admission at the accepting NICU (P < 0.0001); infants whose MCRIB score increased were more likely to die (P < 0.0001)...
  85. ncbi request reprint Rescue high frequency oscillation and predictors of adverse neurodevelopmental outcome in preterm infants
    Gabriel Dimitriou
    Department of Child Health, King s College Hospital, 4th Floor, Ruskin Wing, SE5 9RS, London, UK
    Early Hum Dev 66:133-41. 2002
    ..High frequency oscillation (HFO) is now frequently used as rescue support, but it has been suggested that as many as one-third of survivors have abnormal neurodevelopmental findings at follow-up...
  86. ncbi request reprint Exhaled nitric oxide levels in infants with chronic lung disease
    Jaana A Leipälä
    Department of Child Health, Guy s, King s and St Thomas School of Medicine, King s College Hospital, SE5 9PJ, London, UK
    Eur J Pediatr 163:555-8. 2004
    ..005 and P=0.01 respectively) infants. Regression analysis demonstrated that facemask NO levels were significantly related to CLD, independent of gestational, post-natal and post-conceptional age ( P=0.006)...
  87. ncbi request reprint Acid gastroesophageal reflux in convalescent preterm infants: effect of posture and relationship to apnea
    Ravindra Y Bhat
    Division of Asthma, Allergy and Lung Biology, MRC Asthma Centre, King s College London School of Medicine, London, United Kingdom SE5 9RS
    Pediatr Res 62:620-3. 2007
    ..Supine compared with prone sleeping neither increases clinically important acid GER nor obstructive apnea episodes associated with acid GER in asymptomatic, convalescent, prematurely born infants...
  88. pmc Treatment of neonatal abstinence syndrome
    K Johnson
    Children Nationwide Regional Neonatal Intensive Care Centre, Department of Child Health, King s College Hospital, London SE5 9RS, UK
    Arch Dis Child Fetal Neonatal Ed 88:F2-5. 2003
    ..Many infants with NAS have been exposed to multiple substances in utero. Further research is required into whether a single opiate or a multiple drug regimen is the best option for such patients...
  89. pmc Prediction of extubation failure in preterm infants
    G Dimitriou
    Children Nationwide Regional Neonatal Intensive Care Unit and Department of Respiratory Medicine, King s College Hospital, London, UK
    Arch Dis Child Fetal Neonatal Ed 86:F32-5. 2002
    ..To identify whether the results of assessment of respiratory muscle strength or respiratory load were better predictors of extubation failure in preterm infants than readily available clinical data...
  90. ncbi request reprint First trimester invasive procedures: effects on symptom status and lung volume in very young children
    A Greenough
    Department of Child Health, King s College Hospital, London, United Kingdom
    Pediatr Pulmonol 24:415-22. 1997
    ..01). The symptomatic infants tended to have higher FRCs than the asymptomatic children. We conclude that first trimester procedures are associated with increased respiratory morbidity in very young children...
  91. ncbi request reprint Assessment of prematurely born children at follow-up using a tidal breathing parameter
    A Greenough
    Department of Child Health, King s College Hospital, London, UK
    Physiol Meas 19:111-6. 1998
    ....
  92. ncbi request reprint Pulmonary function at follow-up of very preterm infants from the United Kingdom oscillation study
    Mark R Thomas
    Department of Child Health, Guy s King s and St Thomas Medical School, King s College Hospital, London, UK
    Am J Respir Crit Care Med 169:868-72. 2004
    ..2 (6.0) versus 33.9 (8.0) breaths/minute. We conclude that early use of high-frequency oscillatory ventilation in very preterm infants appears to offer no advantage over CV in terms of pulmonary function at follow-up...
  93. ncbi request reprint Twitch airway pressure elicited by magnetic phrenic nerve stimulation in anesthetized healthy children
    Gerrard F Rafferty
    Department of Child Health, Guy s, King s, and St Thomas School of Medicine, London, UK
    Pediatr Pulmonol 40:141-7. 2005
    ..4% (5.2), 6.7% (3.5), and 11.7% (10.3), respectively. Bilateral and left and right unilateral TwPaw were significantly related to age (P < 0.05). In healthy prepubertal children, diaphragm contractility is primarily influenced by age...
  94. ncbi request reprint Survey of sleeping position recommendations for prematurely born infants on neonatal intensive care unit discharge
    Harish Rao
    Division of Asthma, Allergy and Lung Biology, King s College London, MRC Asthma Centre, Denmark Hill, UK
    Eur J Pediatr 166:809-11. 2007
    ....
  95. ncbi request reprint Survey of sleeping position recommendations for prematurely born infants on neonatal intensive care unit discharge
    Ravindra Y Bhat
    Children Nationwide Regional Neonatal Intensive Care Centre, Department of Child Health, King s College Hospital, London, SE5 9RS, UK
    Eur J Pediatr 162:426-7. 2003
    ..Conclusion: The worrying lack of consistency in recommending non-prone sleeping emphasises that evidence-based guidelines for the sleeping position of convalescent prematurely born infants are required...
  96. ncbi request reprint Lung function in prematurely born infants after viral lower respiratory tract infections
    Simon Broughton
    Division of Asthma, Allergy and Lung Biology, MRC Asthma Centre, King s College London, London, UK
    Pediatr Infect Dis J 26:1019-24. 2007
    ..The aim of this study was to determine the impact of viral LRTI on lung function at follow-up of prematurely born infants...
  97. ncbi request reprint Drugs for the management of respiratory syncytial virus infection
    Simon Broughton
    Children s Nationwide Regional Neonatal Intensive Care Centre, 4th Floor Golden Jubilee Wing, King s College Hospital, London SE5 9RS, UK
    Curr Opin Investig Drugs 5:862-5. 2004
    ..Preliminary results suggest that surfactant, DNase and nitric oxide may be efficacious. Immunoglobulins have no role in the management of acute RSV infection, but passive prophylaxis reduces the hospital admission rate...
  98. doi request reprint Ventilatory strategies for the extremely premature infant
    Anne Greenough
    Division of Asthma, Allergy and Lung Biology, MRC Asthma Centre, King s College London, London, UK
    Paediatr Anaesth 18:371-7. 2008
    ..It is essential in such studies that long-term follow-up assessment is inbuilt so that the benefits/adverse effects can be appropriately identified...
  99. ncbi request reprint Influence of maturation on infant diaphragm function assessed by magnetic stimulation of phrenic nerves
    Gabriel Dimitriou
    Department of Child Health, Guy s, King s and St Thomas School of Medicine, King s College Hospital, London, UK
    Pediatr Pulmonol 35:17-22. 2003
    ..05, and r = 0.56, P < 0.01, respectively). We conclude that gestational age at birth and postconceptional age at time of measurements must be taken into account when interpreting the results of infant diaphragm function tests...
  100. doi request reprint Work of breathing during SIMV with and without pressure support
    D S Patel
    Division of Asthma, Allergy and Lung Biology, School of Medicine, King s College London, London, UK
    Arch Dis Child 94:434-6. 2009
    ..The hypothesis that the addition of pressure support to SIMV compared to SIMV alone would reduce the work of breathing was examined...
  101. doi request reprint Prenatal prediction of neonatal morbidity in survivors with congenital diaphragmatic hernia: a multicenter study
    J C Jani
    Fetal Medicine and Treatment Unit of King s College Hospital, London, UK
    Ultrasound Obstet Gynecol 33:64-9. 2009
    ..To investigate the value of the observed to expected fetal lung area to head circumference ratio (o/e LHR) and liver position in the prediction of neonatal morbidity in survivors with congenital diaphragmatic hernia (CDH)...