Frederic Geissmann

Summary

Affiliation: King's College London
Country: UK

Publications

  1. ncbi Development of monocytes, macrophages, and dendritic cells
    Frederic Geissmann
    Centre for Molecular and Cellular Biology of Inflammation, Division of Immunology, Infection, and Inflammatory Diseases, King s College London, Great Maze Pond, London SE1 1UL, UK
    Science 327:656-61. 2010
  2. ncbi Human CD14dim monocytes patrol and sense nucleic acids and viruses via TLR7 and TLR8 receptors
    Jerome Cros
    U838 INSERM, Universite Paris Descartes, Paris, France
    Immunity 33:375-86. 2010
  3. ncbi Unravelling mononuclear phagocyte heterogeneity
    Frederic Geissmann
    King s College London, Guy s Campus, London SE1 1UL, UK
    Nat Rev Immunol 10:453-60. 2010
  4. ncbi A lineage of myeloid cells independent of Myb and hematopoietic stem cells
    Christian Schulz
    Centre for Molecular and Cellular Biology of Inflammation, New Hunt s House, King s College London, Great Maze Pond, London SE1 1UL, UK
    Science 336:86-90. 2012
  5. ncbi Interaction with activated monocytes enhances cytokine expression and suppressive activity of human CD4+CD45ro+CD25+CD127(low) regulatory T cells
    Gina J Walter
    King s College London, London, UK
    Arthritis Rheum 65:627-38. 2013
  6. ncbi Development and homeostasis of 'resident' myeloid cells: the case of the Langerhans cell
    Laurent Chorro
    Centre for Molecular and Cellular Biology of Inflammation CMCBI, New Hunt s House, King s College London, Great Maze Pond, SE1 1UL, London, UK
    Trends Immunol 31:438-45. 2010
  7. ncbi Langerhans cell (LC) proliferation mediates neonatal development, homeostasis, and inflammation-associated expansion of the epidermal LC network
    Laurent Chorro
    Centre for Molecular and Cellular Biology of Inflammation, Division of Immunobiology, Infection, and Inflammatory Diseases, King s College London, London SE1 1UL, England, UK
    J Exp Med 206:3089-100. 2009
  8. ncbi Development and homeostasis of "resident" myeloid cells: The case of the microglia
    Elisa Gomez Perdiguero
    Centre for Molecular and Cellular Biology of Inflammation CMCBI, King s College London, Great Maze Pond, London, United Kingdom Peter Gorer Department of Immunobiology, King s College London, Great Maze Pond, London, United Kingdom
    Glia 61:112-20. 2013
  9. ncbi FAS/FAS-L dependent killing of activated human monocytes and macrophages by CD4+CD25- responder T cells, but not CD4+CD25+ regulatory T cells
    Ann L Jagger
    Centre for Molecular and Cellular Biology of Inflammation, Division of Immunology, Infection and Inflammatory Disease, King s College London, London SE1 1UL, UK
    J Autoimmun 38:29-38. 2012
  10. ncbi Monocytes control natural killer cell differentiation to effector phenotypes
    Katrina Soderquest
    Medical Research Council Centre for Transplantation, King s College London, London, UK
    Blood 117:4511-8. 2011

Collaborators

Detail Information

Publications11

  1. ncbi Development of monocytes, macrophages, and dendritic cells
    Frederic Geissmann
    Centre for Molecular and Cellular Biology of Inflammation, Division of Immunology, Infection, and Inflammatory Diseases, King s College London, Great Maze Pond, London SE1 1UL, UK
    Science 327:656-61. 2010
    ..Despite this, the origin and differentiation cues for many tissue macrophages, monocytes, and dendritic cell subsets in mice, and the corresponding cell populations in humans, remain to be elucidated...
  2. ncbi Human CD14dim monocytes patrol and sense nucleic acids and viruses via TLR7 and TLR8 receptors
    Jerome Cros
    U838 INSERM, Universite Paris Descartes, Paris, France
    Immunity 33:375-86. 2010
    ..Thus, CD14(dim) cells are bona fide monocytes involved in the innate local surveillance of tissues and the pathogenesis of autoimmune diseases...
  3. ncbi Unravelling mononuclear phagocyte heterogeneity
    Frederic Geissmann
    King s College London, Guy s Campus, London SE1 1UL, UK
    Nat Rev Immunol 10:453-60. 2010
    ..Here, Nature Reviews Immunology asks five experts to discuss the issue of heterogeneity in the mononuclear phagocyte system and to give their opinion on the importance of defining these cells for future research...
  4. ncbi A lineage of myeloid cells independent of Myb and hematopoietic stem cells
    Christian Schulz
    Centre for Molecular and Cellular Biology of Inflammation, New Hunt s House, King s College London, Great Maze Pond, London SE1 1UL, UK
    Science 336:86-90. 2012
    ..These results define a lineage of tissue macrophages that derive from the YS and are genetically distinct from HSC progeny...
  5. ncbi Interaction with activated monocytes enhances cytokine expression and suppressive activity of human CD4+CD45ro+CD25+CD127(low) regulatory T cells
    Gina J Walter
    King s College London, London, UK
    Arthritis Rheum 65:627-38. 2013
    ....
  6. ncbi Development and homeostasis of 'resident' myeloid cells: the case of the Langerhans cell
    Laurent Chorro
    Centre for Molecular and Cellular Biology of Inflammation CMCBI, New Hunt s House, King s College London, Great Maze Pond, SE1 1UL, London, UK
    Trends Immunol 31:438-45. 2010
    ..Beyond LC biology, we propose that YS and HSCs can contribute to the development of distinct subsets of macrophages and DCs...
  7. ncbi Langerhans cell (LC) proliferation mediates neonatal development, homeostasis, and inflammation-associated expansion of the epidermal LC network
    Laurent Chorro
    Centre for Molecular and Cellular Biology of Inflammation, Division of Immunobiology, Infection, and Inflammatory Diseases, King s College London, London SE1 1UL, England, UK
    J Exp Med 206:3089-100. 2009
    ..This mechanism may be relevant in locations where leukocyte trafficking is limited...
  8. ncbi Development and homeostasis of "resident" myeloid cells: The case of the microglia
    Elisa Gomez Perdiguero
    Centre for Molecular and Cellular Biology of Inflammation CMCBI, King s College London, Great Maze Pond, London, United Kingdom Peter Gorer Department of Immunobiology, King s College London, Great Maze Pond, London, United Kingdom
    Glia 61:112-20. 2013
    ..2012 Wiley Periodicals, Inc...
  9. ncbi FAS/FAS-L dependent killing of activated human monocytes and macrophages by CD4+CD25- responder T cells, but not CD4+CD25+ regulatory T cells
    Ann L Jagger
    Centre for Molecular and Cellular Biology of Inflammation, Division of Immunology, Infection and Inflammatory Disease, King s College London, London SE1 1UL, UK
    J Autoimmun 38:29-38. 2012
    ....
  10. ncbi Monocytes control natural killer cell differentiation to effector phenotypes
    Katrina Soderquest
    Medical Research Council Centre for Transplantation, King s College London, London, UK
    Blood 117:4511-8. 2011
    ..Together, these data reveal a novel, unrecognized role for Txb21 expression in monocytes in promoting NK-cell development and help appreciate how various NK-cell subsets are generated and participate in antitumor immunity...
  11. ncbi Monocytes in atherosclerosis: subsets and functions
    Kevin J Woollard
    Center for Molecular and Cellular Biology of Inflammation CMCBI, Division of Immunology, Infection and Inflammatory Diseases DIIID, Guys Campus, London SE1 1UL, UK
    Nat Rev Cardiol 7:77-86. 2010
    ....