Research Topics
Species | P T FrancisSummaryAffiliation: King's College Country: UK Publications
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Detail Information
Publications
The cholinergic hypothesis of Alzheimer's disease: a review of progressP T Francis
Dementia Research Laboratory, Neuroscience Research Centre, Guy s, King s and St Thomas Schools of Biomedical Sciences, King s College, London, UK
J Neurol Neurosurg Psychiatry 66:137-47. 1999..Indeed, three compounds have received European approval for the treatment of the cognitive symptoms of Alzheimer's disease, first tacrine and more recently, donepezil and rivastigmine, all of which are cholinesterase inhibitors...
Pyramidal neurone modulation: a therapeutic target for Alzheimer's diseaseP T Francis
Dementia Research Laboratory, United Medical School of Guy s Hospital, London
Neurodegeneration 5:461-5. 1996..The contribution of pyramidal neurone transmission failure to the spread of pathology in AD is the subject of continuing investigation...
Altered glutamate neurotransmission and behaviour in dementia: evidence from studies of memantineP T Francis
King s College London, Wolfson Centre for Age Related Diseases, London, UK
Curr Mol Pharmacol 2:77-82. 2009....
Expression of amyloid precursor protein, tau and presenilin RNAs in rat hippocampus following deafferentation lesionsM J Ramirez
Biochemical Neuropharmacology Group, Centre for Neuroscience Research, GKT School of Biomedical Sciences, King's College London, Hodgkin Building, Guy's Hospital Campus, SE1 1UL, London, UK
Brain Res 907:222-32. 2001....
Vesicular glutamate transporter and cognition in stroke: a case-control autopsy studyS L Kirvell
King s College London, Wolfson Centre for Age Related Diseases, London, UK
Neurology 75:1803-9. 2010..We have therefore investigated glutamatergic synaptic markers in VaD...
