Abebaw Fekadu

Summary

Affiliation: King's College London
Country: UK

Publications

  1. pmc Suicide and suicide attempts in people with severe mental disorders in Butajira, Ethiopia: 10 year follow-up of a population-based cohort
    Teshome Shibre
    Department of Psychiatry, Addis Ababa University, College of Health Sciences, School of Medicine, Addis Ababa, Ethiopia
    BMC Psychiatry 14:150. 2014
  2. doi request reprint Adjuvant therapy with minocycline for schizophrenia (The MINOS Trial): study protocol for a double-blind randomized placebo-controlled trial
    Abebaw Fekadu
    Department of Psychiatry, School of Medicine, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia
    Trials 14:406. 2013
  3. ncbi request reprint Long-term impact of residual symptoms in treatment-resistant depression
    Abebaw Fekadu
    King s College London, Institute of Psychiatry, Section of Neurobiology of Mood Disorders, England, UK
    Can J Psychiatry 56:549-57. 2011
  4. ncbi request reprint Toxoplasmosis as a cause for behaviour disorders--overview of evidence and mechanisms
    Abebaw Fekadu
    Department of Psychiatry, Faculty of Medicine, Addis Ababa University, Addis Ababa, Ethiopia
    Folia Parasitol (Praha) 57:105-13. 2010
  5. doi request reprint Prediction of longer-term outcome of treatment-resistant depression in tertiary care
    Abebaw Fekadu
    Department of Psychiatry, School of Medicine, College of Health Sciences, Addis Ababa University, PO Box 9086, Addis Ababa, Ethiopia
    Br J Psychiatry 201:369-75. 2012
  6. doi request reprint Longitudinal course of symptom severity and fluctuation in patients with treatment-resistant unipolar and bipolar depression
    Francis K Vergunst
    King s College London, Institute of Psychiatry, Department of Psychological Medicine, Affective Disorders Research Group, Box P074, 103 Denmark Hill, SE5 8AF, London, UK
    Psychiatry Res 207:143-9. 2013
  7. doi request reprint Validity of the concept of minor depression in a developing country setting
    Abebaw Fekadu
    Section of Epidemiology, Health Services Research Department, Institute of Psychiatry, King s College London, UK
    J Nerv Ment Dis 196:22-8. 2008
  8. pmc Trimethoprim as adjuvant treatment in schizophrenia: a double-blind, randomized, placebo-controlled clinical trial
    Teshome Shibre
    Department of Psychiatry, Faculty of Medicine, Addis Ababa University, Addis Ababa, Ethiopia
    Schizophr Bull 36:846-51. 2010
  9. doi request reprint Five-year clinical course and outcome of schizophrenia in Ethiopia
    Solomon Teferra
    Department of Psychiatry, Faculty of Medicine, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia
    Schizophr Res 136:137-42. 2012
  10. pmc Clinical course and outcome of schizophrenia in a predominantly treatment-naive cohort in rural Ethiopia
    Atalay Alem
    Medical Faculty, Department of Psychiatry, Addis Ababa University, Addis Ababa, Ethiopia
    Schizophr Bull 35:646-54. 2009

Collaborators

Detail Information

Publications24

  1. pmc Suicide and suicide attempts in people with severe mental disorders in Butajira, Ethiopia: 10 year follow-up of a population-based cohort
    Teshome Shibre
    Department of Psychiatry, Addis Ababa University, College of Health Sciences, School of Medicine, Addis Ababa, Ethiopia
    BMC Psychiatry 14:150. 2014
    ..However, research into suicide attempts and completed suicide in people with SMD in low- and middle-income countries is mostly limited to patients attending psychiatric facilities where selection bias is likely to be high...
  2. doi request reprint Adjuvant therapy with minocycline for schizophrenia (The MINOS Trial): study protocol for a double-blind randomized placebo-controlled trial
    Abebaw Fekadu
    Department of Psychiatry, School of Medicine, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia
    Trials 14:406. 2013
    ..In this study we aim to assess the efficacy of adjunctive minocycline to alleviate symptoms of schizophrenia in patients who have failed to respond to a therapeutic trial of antipsychotic medications...
  3. ncbi request reprint Long-term impact of residual symptoms in treatment-resistant depression
    Abebaw Fekadu
    King s College London, Institute of Psychiatry, Section of Neurobiology of Mood Disorders, England, UK
    Can J Psychiatry 56:549-57. 2011
    ..The aim of our study was to assess the impact of posttreatment clinical states on longer-term outcome...
  4. ncbi request reprint Toxoplasmosis as a cause for behaviour disorders--overview of evidence and mechanisms
    Abebaw Fekadu
    Department of Psychiatry, Faculty of Medicine, Addis Ababa University, Addis Ababa, Ethiopia
    Folia Parasitol (Praha) 57:105-13. 2010
    ..The neurotropic protozoan parasite Toxoplasma gondii is one of the main candidates and has been associated with various psychiatric conditions, including schizophrenia...
  5. doi request reprint Prediction of longer-term outcome of treatment-resistant depression in tertiary care
    Abebaw Fekadu
    Department of Psychiatry, School of Medicine, College of Health Sciences, Addis Ababa University, PO Box 9086, Addis Ababa, Ethiopia
    Br J Psychiatry 201:369-75. 2012
    ..Systematic studies on the outcome of treatment-resistant depression are scarce...
  6. doi request reprint Longitudinal course of symptom severity and fluctuation in patients with treatment-resistant unipolar and bipolar depression
    Francis K Vergunst
    King s College London, Institute of Psychiatry, Department of Psychological Medicine, Affective Disorders Research Group, Box P074, 103 Denmark Hill, SE5 8AF, London, UK
    Psychiatry Res 207:143-9. 2013
    ..We suggest that the longitudinal illness course is an important outcome to be considered in future TRD research...
  7. doi request reprint Validity of the concept of minor depression in a developing country setting
    Abebaw Fekadu
    Section of Epidemiology, Health Services Research Department, Institute of Psychiatry, King s College London, UK
    J Nerv Ment Dis 196:22-8. 2008
    ..Minor depressive disorder seems to be a useful and valid diagnostic construct with particular clinical significance in this and, possibly, similar developing country settings...
  8. pmc Trimethoprim as adjuvant treatment in schizophrenia: a double-blind, randomized, placebo-controlled clinical trial
    Teshome Shibre
    Department of Psychiatry, Faculty of Medicine, Addis Ababa University, Addis Ababa, Ethiopia
    Schizophr Bull 36:846-51. 2010
    ....
  9. doi request reprint Five-year clinical course and outcome of schizophrenia in Ethiopia
    Solomon Teferra
    Department of Psychiatry, Faculty of Medicine, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia
    Schizophr Res 136:137-42. 2012
    ..We reported the short-term follow-up which showed unfavorable outcome. We followed-up the cohort further to determine the 5-year outcome of schizophrenia and to compare the results with the WHO reports...
  10. pmc Clinical course and outcome of schizophrenia in a predominantly treatment-naive cohort in rural Ethiopia
    Atalay Alem
    Medical Faculty, Department of Psychiatry, Addis Ababa University, Addis Ababa, Ethiopia
    Schizophr Bull 35:646-54. 2009
    ..Improving access to treatment may be the logical next step to improve outcome of schizophrenia in this setting...
  11. doi request reprint Prospective evaluation of specialist inpatient treatment for refractory affective disorders
    Sarah C Wooderson
    King s College London, Institute of Psychiatry, Department of Psychological Medicine, Section of Neurobiology of Mood Disorders, London SE5 8AZ, UK
    J Affect Disord 131:92-103. 2011
    ..Little data exist to inform the treatment of severe and resistant affective disorders. We report here the effectiveness of specialist multimodal inpatient treatment for refractory affective disorders...
  12. ncbi request reprint A multidimensional tool to quantify treatment resistance in depression: the Maudsley staging method
    Abebaw Fekadu
    King s College London, Institute of Psychiatry, Section of Neurobiology of Mood Disorders, Department of Psychological Medicine and Psychiatry, London, UK
    J Clin Psychiatry 70:177-84. 2009
    ..However, current unitary models of staging fail to represent its complexity. We aimed to devise a model to stage treatment-resistant depression, taking into account the core factors contributing to treatment failure...
  13. ncbi request reprint The impact of childhood adversity on suicidality and clinical course in treatment-resistant depression
    Catherine Tunnard
    Division of Psychological Medicine and Psychiatry, Section of Neurobiology of Mood Disorders, Institute of Psychiatry, King s College London, 103 Denmark Hill, London SE5 8AZ, UK The National Affective Disorder Unit, South London and Maudsley NHS Foundation Trust, UK
    J Affect Disord 152:122-30. 2014
    ..Childhood adversity is a risk factor for the development of depression and can also affect clinical course. We investigated this specifically in treatment-resistant depression (TRD)...
  14. pmc Five-year mortality in a cohort of people with schizophrenia in Ethiopia
    Solomon Teferra
    Department of Psychiatry, School of Medicine, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia
    BMC Psychiatry 11:165. 2011
    ..Both natural and unnatural causes were reported. However, there is dearth of evidence from low and middle income (LAMIC) countries, particularly in Africa. To our knowledge this is the first community based report from Africa...
  15. ncbi request reprint Utility of the concept of minor depressive disorder: evidence from a large rural community sample in a developing country setting
    Abebaw Fekadu
    King s College London, Institute of Psychiatry, London, UK
    J Affect Disord 104:111-8. 2007
    ..Evidence on the utility of the minor depressive disorder diagnostic construct in rural communities and developing countries is scarce...
  16. ncbi request reprint The Maudsley Staging Method for treatment-resistant depression: prediction of longer-term outcome and persistence of symptoms
    Abebaw Fekadu
    Institute of Psychiatry, Section of Neurobiology of Mood Disorders, Department of Psychological Medicine and Psychiatry, King s College London, United Kingdom
    J Clin Psychiatry 70:952-7. 2009
    ..We hypothesized that patients with higher scores on the MSM would experience a worse longer-term outcome in terms of time spent in a depressive episode and level of functional impairment...
  17. ncbi request reprint Predictors of carer-burden in schizophrenia: a five-year follow-up study in Butajira, Ethiopia
    Teshome Shibre
    Addis Ababa University, Faculty of Medicine, Department of Psychiatry, Addis Ababa, Ethiopia
    Ethiop Med J 50:125-33. 2012
    ..We assessed carer-burden and its predictors in a traditional rural Ethiopian community in order to establish the longitudinal course of carer-burden and factors predicting changes...
  18. ncbi request reprint Long-term symptomatic and functional outcome following an intensive inpatient multidisciplinary intervention for treatment-resistant affective disorders
    Sarah C Wooderson
    King s College London, Institute of Psychiatry, Department of Psychological Medicine, Affective Disorders Research Group, 103 Denmark Hill, London SE5 8AZ, UK The National Affective Disorders Unit, South London and Maudsley NHS Foundation Trust, Bethlem Royal Hospital, Monks Orchard Road, Beckenham, Kent BR3 3BX, UK
    J Affect Disord 166:334-42. 2014
    ..The natural history of treatment-resistant depression (TRD) is poor, with high rates of chronicity and recurrence. We describe longer-term symptomatic and functional outcome following multimodal intensive inpatient treatment for TRD...
  19. pmc Internalized stigma among patients with schizophrenia in Ethiopia: a cross-sectional facility-based study
    Dereje Assefa
    Amanuel Specialized Mental Hospital, Addis Ababa, Ethiopia
    BMC Psychiatry 12:239. 2012
    ..We conducted a study to determine the extent, domains and correlates of internalized stigma amongst outpatients with schizophrenia in Ethiopia...
  20. doi request reprint What happens to patients with treatment-resistant depression? A systematic review of medium to long term outcome studies
    Abebaw Fekadu
    King s College London, Institute of Psychiatry, Division of Psychological Medicine, Section of Neurobiology of Mood Disorders, PO 074, 103 Denmark Hill, London, SE5 8AZ, UK
    J Affect Disord 116:4-11. 2009
    ..We conducted a systematic review of outcome studies of TRD in order to summarise findings on the longer term outcome of TRD and make recommendations...
  21. ncbi request reprint Community diagnosis of common skin diseases in the Zay community of the Zeway Islands, Ethiopia
    Ruth Leekassa
    ALERT Hospital, Addis Ababa, Ethiopia
    Ethiop Med J 43:189-95. 2005
    ..Skin diseases are common public health problems throughout the world. Studies on skin problems are rare in Ethiopia. Easy and cheap methods of identifying skin conditions in the community are poorly developed in the country...
  22. doi request reprint Violence and violent victimization in people with severe mental illness in a rural low-income country setting: a comparative cross-sectional community study
    Ruth Tsigebrhan
    Addis Ababa University, College of Health Sciences, School of Medicine, Department of Psychiatry, Addis Ababa, Ethiopia Electronic address
    Schizophr Res 152:275-82. 2014
    ..Violence perpetrated by and against people with severe mental illness (SMI) is important but rarely investigated in low- and middle income countries...
  23. pmc Challenges and opportunities for implementing integrated mental health care: a district level situation analysis from five low- and middle-income countries
    Charlotte Hanlon
    Department of Psychiatry, School of Medicine, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia Centre for Global Mental Health, Institute of Psychiatry, King s College London, London, United Kingdom
    PLoS ONE 9:e88437. 2014
    ..The purpose was to inform development and implementation of a comprehensive district plan to integrate mental health into primary care...
  24. ncbi request reprint The distribution of mental disorders among an isolated island community in southern Ethiopia
    Derege Kebede
    Department of Community Health, Addis Ababa University, Ethiopia
    Ethiop Med J 43:71-7. 2005
    ..The Zeway islanders are completely different from the surrounding cultural groups, in the midst of whom they have been living in isolation for over three centuries...