Research Topics
| Paul FearonSummaryAffiliation: King's College London Country: UK Publications
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Detail Information
Publications
Relation between headache in childhood and physical and psychiatric symptoms in adulthood: national birth cohort studyP Fearon
Institute of Psychiatry and Guy s, King s and St Thomas s School of Medicine, De Crespigny Park, London SE5 8AF
BMJ 322:1145. 2001..To elucidate the associations between frequent headache and psychosocial factors in childhood and to determine whether such children are at an increased risk of headache, multiple physical symptoms, and psychiatric symptoms in adulthood...
Incidence of schizophrenia and other psychoses in ethnic minority groups: results from the MRC AESOP StudyPaul Fearon
Division of Psychological Medicine, Institute of Psychiatry, King s College, London, UK
Psychol Med 36:1541-50. 2006..We sought to clarify whether (a) the rates of other psychotic disorders are increased, (b) whether psychosis is increased in other ethnic minority groups, and (c) whether particular age or gender groups are especially at risk...- Brain volumes in adult survivors of very low birth weight: a sibling-controlled studyPaul Fearon
Section of General Psychiatry, Division of Psychological Medicine, Box 63, Institute of Psychiatry, London SE5 8AF, United Kingdom
Pediatrics 114:367-71. 2004..To establish whether adults who were born very low birth weight (VLBW) show altered volumes of certain brain structures... 
Neurological abnormalities and cognitive ability in first-episode psychosisPaola Dazzan
Department of Psychiatry, Box 63, Institute of Psychiatry, De Crespigny Park, London SE5 8AF, UK
Br J Psychiatry 193:197-202. 2008....- Specific and generalized neuropsychological deficits: a comparison of patients with various first-episode psychosis presentationsJolanta Zanelli
Institute of Psychiatry, PO63, Division of Psychological Medicine and Psychiatry, De Crespigny Park, Denmark Hill, London SE5 8AF, UK
Am J Psychiatry 167:78-85. 2010..In the context of four distinct diagnostic groups, the authors compared neuropsychological performance among patients experiencing their first psychotic episode... - Selective deficits in semantic verbal fluency in patients with a first affective episode with psychotic symptoms and a positive history of maniaEugenia Kravariti
Department of Psychiatry, NIHR Biomedical Research Centre, Maudsley NHS Foundation Trust Institute of Psychiatry, King s College London, Box 58, De Crespigny Park, London SE5 8AF, UK
Bipolar Disord 11:323-9. 2009..We investigated neuropsychological performance in an epidemiologically derived sample of patients with a first affective episode with psychotic symptoms and a positive history of mania, compared to community controls... - Duration of untreated psychosis and neuropsychological function in first episode psychosisJulia M Lappin
Kings College Hospital Institute of Psychiatry, Division of Psychological Medicine, PO63, De Crespigny Park, Denmark Hill, London, SE5 8AF, UK
Schizophr Res 95:103-10. 2007..We predicted that longer DUP would be associated with greater neurocognitive impairment... - Duration of prodromal phase and severity of volumetric abnormalities in first-episode psychosisJulia M Lappin
King s College London, Institute of Psychiatry, London, UK
Br J Psychiatry Suppl 51:s123-7. 2007..First-episode psychosis is typically preceded by a prodrome in which there is deterioration in global and social functioning... - Childhood trauma and cognitive function in first-episode affective and non-affective psychosisMonica Aas
Department of Psychological Medicine, Institute of Psychiatry, King s College London, UK
Schizophr Res 129:12-9. 2011..The potential impact of diagnosis (schizophrenia or affective psychosis) and gender on this association was also examined... - Reliability and comparability of psychosis patients' retrospective reports of childhood abuseHelen L Fisher
Institute of Psychiatry, King s College London, De Crespigny Park, London SE5 8AF, UK
Schizophr Bull 37:546-53. 2011..159, P=.419; antipathy: χ(2)=0.868, P=.229; neglect: χ(2)=0.639, P=.274). These findings provide justification for the use in future studies of retrospective reports of childhood abuse obtained from individuals with psychotic disorders... - Different effects of typical and atypical antipsychotics on grey matter in first episode psychosis: the AESOP studyPaola Dazzan
Division of Psychological Medicine, Institute of Psychiatry, King s College, London, UK
Neuropsychopharmacology 30:765-74. 2005..In conclusion, we would like to suggest that even after short-term treatment, typical and atypical antipsychotics may affect brain structure differently... - Is there a link between childhood trauma, cognition, and amygdala and hippocampus volume in first-episode psychosis?Monica Aas
Department of Psychosis Studies, Institute of Psychiatry, King s College London, London, UK
Schizophr Res 137:73-9. 2012..This points to a complex relationship between childhood trauma exposure, cognitive function and amygdala volume in first-episode psychosis... - Familial liability to schizophrenia and premorbid adjustmentMuriel Walshe
Division of Psychological Medicine, Institute of Psychiatry, De Crespigny Park, London SE5 8AF, UK
Br J Psychiatry 191:260-1. 2007..Unaffected siblings from multiply affected families also had poor academic functioning in adolescence, with a decline between childhood and adolescence. This may represent a familial (presumed genetic) effect... - Sexually dimorphic changes in the amygdala in relation to delusional beliefs in first episode psychosisAyana A Gibbs
Division of Psychological Medicine, Institute of Psychiatry, King s College, P O Box, De Crespigny Park, London SE5 8AF, UK
J Psychiatr Res 42:913-9. 2008..The present study explored the relationship between amygdala morphology and mood congruent and mood incongruent delusional beliefs... - Parental separation, loss and psychosis in different ethnic groups: a case-control studyCraig Morgan
Division of Psychological Medicine, Institute of Psychiatry, London, UK
Psychol Med 37:495-503. 2007..We sought to investigate the relationship between long-term separation from, and death of, a parent before the age of 16 and risk of adult psychosis in different ethnic groups... - Assessment of posttraumatic symptoms in patients with first-episode psychosisIngo Schafer
Universitatsklinikum Hamburg Eppendorf, Martinistrasse 52, Hamburg, Germany
J Nerv Ment Dis 199:896-8. 2011..Overall, the findings suggest that the IES can be used to assess symptoms of posttraumatic stress in patients with psychotic disorders as in other populations... - Long-term maternal recall of obstetric complications in schizophrenia researchMuriel Walshe
King s College London, King s Health Partners, Institute of Psychiatry, Department of Psychosis Studies and NIHR Biomedical Research Centre, London, SE5 8AF, UK
Psychiatry Res 187:335-40. 2011..Assessing the cognition of participants in retrospective studies may allow future studies to increase the reliability of their data... - Gray matter abnormalities associated with duration of untreated psychosisJulia M Lappin
Kings College London Institute of Psychiatry, PO63, Division of Psychological Medicine, King s College London, London SE5 8AF, United Kingdom
Schizophr Res 83:145-53. 2006..In order to identify whether an anatomically mediated mechanism may give rise to poorer outcomes, it is important to identify whether a long DUP is associated with greater brain structural abnormalities... - The structural brain correlates of neurological soft signs in healthy individualsPaola Dazzan
King s College London, Institute of Psychiatry, Division of Psychological Medicine, London, UK
Cereb Cortex 16:1225-31. 2006..Therefore, we suggest that these cortical brain structural changes represent a common neuroanatomical substrate of NSS, across healthy individuals and patients with psychosis... - Satisfaction with inpatient treatment for first-episode psychosis among different ethnic groups: a report from the UK AeSOP studyJane Boydell
Psychosis Clinical Academic Group, Institute of Psychiatry, King s Health Partners, King s College London, UK
Int J Soc Psychiatry 58:98-105. 2012..There is concern about the level of satisfaction with mental healthcare among minority ethnic patients in the UK, particularly as black patients have more compulsory admissions to hospital... - Gender differences in the association between childhood abuse and psychosisHelen Fisher
PO 80, Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, De Crespigny Park, London SE5 8AF, UK
Br J Psychiatry 194:319-25. 2009..Studies demonstrating an association between childhood trauma and psychosis in adulthood have not systematically explored gender differences... - Self-harm in first-episode psychosisSamuel B Harvey
Department of Psychological Medicine, Institute of Psychiatry, King s College London, Weston Education Centre, 10 Cutcombe Road, London SE5 9RJ, UK
Br J Psychiatry 192:178-84. 2008..Little is known about self-harm occurring during the period of untreated first-episode psychosis... - The economic cost of pathways to care in first episode psychosisMargaret Heslin
Department of Psychosis Studies, Institute of Psychiatry, Kings College London, UK
Int Rev Psychiatry 23:55-60. 2011..This should be considered when the National Health Service (NHS) is making decisions about funding... - Duration of untreated psychosis and ethnicity in the AESOP first-onset psychosis studyCraig Morgan
Division of Psychological Medicine, Institute of Psychiatry, De Crespigny Park, London, UK
Psychol Med 36:239-47. 2006..There is a common assumption that Black patients with a psychotic mental illness experience longer treatment delays during a first episode. We sought to investigate this issue in a large cohort of patients with a first episode of psychosis... - Unemployment, social isolation, achievement-expectation mismatch and psychosis: findings from the AESOP StudyUlrich A Reininghaus
Health Services and Population Research Department, Institute of Psychiatry, King s College, De Crespigny Park, London, UK
Soc Psychiatry Psychiatr Epidemiol 43:743-51. 2008.... - Effects of very low birthweight on brain structure in adulthoodMatthew Allin
Department of Psychiatry, Institute of Psychiatry, King s College, London, UK
Dev Med Child Neurol 46:46-53. 2004..We conclude that these diffuse abnormalities of grey and white matter are a consequence of the interaction of perinatal brain injury and ongoing neurodevelopmental processes... - Increased pituitary volume in antipsychotic-free and antipsychotic-treated patients of the AEsop first-onset psychosis studyCarmine M Pariante
Stress, Psychiatry and Immunology Laboratory, Division of Psychological Medicine, Clinical Neuropharmacology PO51, Institute of Psychiatry, King s College London, 1 Windsor Walk, Denmark Hill, London SE5 8AF, UK
Neuropsychopharmacology 30:1923-31. 2005..This activation of the hormonal stress response could participate to the important metabolic abnormalities observed in patients with psychosis... - Clinical and social determinants of duration of untreated psychosis in the AESOP first-episode psychosis studyCraig Morgan
Division of Psychological Medicine, Institute of Psychiatry, De Crespigny Park, London SE5 8AF, UK
Br J Psychiatry 189:446-52. 2006..Despite considerable research investigating the relationship between a long duration of untreated psychosis (DUP) and outcomes, there has been much less considering predictors of a long DUP... - Linear and non-linear associations of symptom dimensions and cognitive function in first-onset psychosisEugenia Kravariti
NIHR Biomedical Research Centre for Mental Health, South London and Maudsley NHS Foundation Trust and Institute of Psychiatry, King s College London, De Crespigny Park, London SE5 8AF, UK
Schizophr Res 140:221-31. 2012..It also extended the research focus to mania, a less studied symptom dimension... - Length of stay of general psychiatric inpatients in the United States: systematic reviewAlex D Tulloch
Department of Psychiatry, Institute of Psychiatry, Kings College London, De Crespigny Park, London, SE5 8AF, UK
Adm Policy Ment Health 38:155-68. 2011..Associations appeared consistent, especially where sample size was above 3,000. Updated studies should be adequately powered and include the variables above... - The determinants and outcomes of long-stay psychiatric admissions: a case-control studyAlex D Tulloch
Division of Psychological Medicine and Psychiatry, Institute of Psychiatry, King s College London, De Crespigny Park, London, SE5 8AF, UK
Soc Psychiatry Psychiatr Epidemiol 43:569-74. 2008..Previous studies have suggested an association between long-stay and both schizophrenia and challenging behaviour, as well as rehousing or placement difficulties, but no UK study to date has compared such cases with control admissions... - Differential relationship between neurological and cognitive dysfunction in first episode psychosis patients and in healthy individualsZefiro Mellacqua
King s College London, Institute of Psychiatry, Department of Psychosis Studies, London, UK
Schizophr Res 142:159-64. 2012..004); and motor signs with poorer verbal abilities (p=0.001). These findings indicate the presence of specific associations between neurological and cognitive deficits in psychosis that are distinct from those of healthy individuals... - The role of ethnicity in clinical psychopathology and care pathways of adults with intellectual disabilitiesElias Tsakanikos
Estia Centre, Institute of Psychiatry, King s College London, 66 Snowsfields, London SE1 3SS, UK
Res Dev Disabil 31:410-5. 2010..The results are discussed in the context of cultural and familial factors in particular ethnic groups that may play an important role in accessing and using mental health services... - Suicide and other causes of mortality in bipolar disorder: a longitudinal studyRina Dutta
Division of Psychiatry and Psychological Medicine, Institute of Psychiatry, London, UK
Psychol Med 37:839-47. 2007..There is conflicting evidence about deaths from other causes and little known about risk factors for suicide. We aimed to estimate suicide and mortality rates in a cohort of bipolar patients and to identify risk factors for suicide... - Residential mobility among individuals with severe mental illness: cohort study of UK700 participantsAlex D Tulloch
Department of Psychiatry, Institute of Psychiatry, Kings College London, De Crespigny Park, London, SE5 8AF, UK
Soc Psychiatry Psychiatr Epidemiol 45:767-77. 2010..There is limited research concerning residential mobility among people with severe mental illness... - Residential mobility among patients admitted to acute psychiatric wardsAlex D Tulloch
King s College London, King s Health Partners, Institute of Psychiatry, De Crespigny Park, London SE5 8AF, UK
Health Place 17:859-66. 2011..Unadjusted effects of gender, marital status and previous service use were mediated by homelessness. Possible mechanisms for the associations with homelessness and younger age are discussed... - Criminal offending and distinguishing features of offenders among persons experiencing a first episode of psychosisSheilagh Hodgins
Department of Forensic and Neurodevelopmental Sciences, Institute of Psychiatry, King s College London, London, UK
Early Interv Psychiatry 5:15-23. 2011..Most offenders with SMI acquire convictions prior to contact with mental health services. This study examined offending among 301 individuals experiencing their first episode of psychosis... - Timing, prevalence, determinants and outcomes of homelessness among patients admitted to acute psychiatric wardsAlex D Tulloch
Department of Psychosis Studies, Institute of Psychiatry, Kings College London, De Crespigny Park, London, SE5 8AF, UK
Soc Psychiatry Psychiatr Epidemiol 47:1181-91. 2012..To document the prevalence, timing, associations and short-term housing outcomes of homelessness among acute psychiatric inpatients... - Neuropsychological functioning in first-episode schizophreniaEugenia Kravariti
Department of Psychiatry, NIHR Biomedical Research Centre for Mental Health, South London and Maudsley NHS Foundation Trust and Institute of Psychiatry, King s College London, London
Br J Psychiatry 195:336-45. 2009.... - The structural brain correlates of neurological soft signs in AESOP first-episode psychoses studyPaola Dazzan
Division of Psychological Medicine, Box 63, Institute of Psychiatry, De Crespigny Park, London SE5 8AF, UK
Brain 127:143-53. 2004.... - Environmental factors in schizophrenia: the role of migrant studiesPaul Fearon
Division of Psychological Medicine, Institute of Psychiatry, King s College, London
Schizophr Bull 32:405-8. 2006..The challenge for the next phase of studies is to identify the relevant risk factors and how they might interact to increase the risk of psychosis, both in migrant groups and in the general population... - Associations of homelessness and residential mobility with length of stay after acute psychiatric admissionAlex D Tulloch
King s College London, King s Health Partners, Institute of Psychiatry, De Crespigny Park, London, SE5 8AF, UK
BMC Psychiatry 12:121. 2012..abstract:.. - Dermatoglyphics and Schizophrenia: a meta-analysis and investigation of the impact of obstetric complications upon a-b ridge countElvira Bramon
Division of Psychological Medicine, Institute of Psychiatry, P O Box 63, De Crespigny Park, London SE5 8AF, UK
Schizophr Res 75:399-404. 2005..However, the severity or the origin of these ABRC changes has not been established... - Social outcomes in schizophrenia: from description to actionAlex D Tulloch
Department of Psychological Medicine, Institute of Psychiatry, London, UK
Curr Opin Psychiatry 19:140-4. 2006..The studies we reviewed looked at the effects on summary measures, for example, quality of life, as well as simpler, more self-explanatory outcomes such as employment, marital status, financial independence and housing... - Gender differences in incidence and age at onset of mania and bipolar disorder over a 35-year period in Camberwell, EnglandNoel Kennedy
Section of General Psychiatry, Division of Psychological Medicine, Institute of Psychiatry, De Crespigny Park, London SE5 8AF, UK
Am J Psychiatry 162:257-62. 2005..The authors investigated gender differences in age at onset and incidence of first-episode mania and bipolar disorder in an epidemiological catchment area in southeast London over a 35-year period... - Grey matter abnormalities in first-episode schizophrenia and affective psychosisKevin D Morgan
Department of Psychology, University of Westminster, 309 Regent Street, London W1B 2UW, UK
Br J Psychiatry Suppl 51:s111-6. 2007..Grey matter and other structural brain abnormalities are consistently reported in first-onset schizophrenia, but less is known about the extent of neuroanatomical changes in first-onset affective psychosis... - Intellectual function and schizophreniaPaul Fearon
Br J Psychiatry 181:276-7. 2002 - The relationship between predisposing factors, premorbid function and symptom dimensions in psychosis: an integrated approachAlmudena Guerra
Gerencia Torribera, Santa Coloma de Gramenet, Barcelona, Spain
Eur Psychiatry 17:311-20. 2002..On the other hand, neither mania nor depression was associated with childhood dysfunction. Our most striking finding was that disorganisation appeared to arise when a familial predisposition to mania was compounded by low premorbid IQ... - Heterogeneity in incidence rates of schizophrenia and other psychotic syndromes: findings from the 3-center AeSOP studyJames B Kirkbride
Department of Psychiatry, University of Cambridge, Cambridge, England
Arch Gen Psychiatry 63:250-8. 2006..Convention suggests uniformity of incidence of schizophrenia and other psychoses; variation would have implications for their causes and biological characteristics... - Neighbourhood variation in the incidence of psychotic disorders in Southeast LondonJames B Kirkbride
Dept of Psychiatry, University of Cambridge, Box 189, Cambridge CB2 2QQ, UK
Soc Psychiatry Psychiatr Epidemiol 42:438-45. 2007..Urbanicity is a risk factor for schizophrenia, but it is unclear whether this risk is homogenous across urban areas... - Perceptions of disadvantage, ethnicity and psychosisClaudia Cooper
UCL Department of Mental Health Sciences, London W1W 7EY, UK
Br J Psychiatry 192:185-90. 2008..People from Black ethnic groups (African-Caribbean and Black African) are more prone to develop psychosis in Western countries. This excess might be explained by perceptions of disadvantage... - Incidence of bipolar affective disorder in three UK cities: results from the AESOP studyTuhina Lloyd
Division of Psychiatry, University of Nottingham, Nottingham, UK
Br J Psychiatry 186:126-31. 2005..There has been a relative dearth of epidemiological research into bipolar affective disorder. Furthermore, incidence studies of bipolar disorder have been predominantly retrospective and most only included hospital admission cases... - Neighbourhood-level effects on psychoses: re-examining the role of contextJames B Kirkbride
Department of Psychiatry, University of Cambridge, Cambridge, UK
Psychol Med 37:1413-25. 2007..Cross-level interactions are poorly understood. We investigated these issues using data from the Aetiology and Ethnicity in Schizophrenia and Other Psychoses (AESOP) study... - Social experience and psychosis insights from studies of migrant and ethnic minority groupsCraig Morgan
Epidemiol Psichiatr Soc 16:118-23. 2007..A more complete understanding of these factors may help us to clarify why there are differences in rates between populations...