Anne Farmer

Summary

Affiliation: King's College London
Country: UK

Publications

  1. ncbi request reprint Prevalence of chronic disabling fatigue in children and adolescents
    Anne Farmer
    MRC Social, Genetic, Developmental Psychiatric Research Centre, Institute of Psychiatry, London, UK
    Br J Psychiatry 184:477-81. 2004
  2. pmc The definition of disabling fatigue in children and adolescents
    Tom Fowler
    Department of Psychological Medicine, Wales College of Medicine, Cardiff University, UK
    BMC Fam Pract 6:33. 2005
  3. doi request reprint Moderation of antidepressant response by the serotonin transporter gene
    Patricia Huezo-Diaz
    Institute of Psychiatry, King s College London, UK
    Br J Psychiatry 195:30-8. 2009
  4. doi request reprint Genome-wide pharmacogenetics of antidepressant response in the GENDEP project
    Rudolf Uher
    Medical Research Council Social, Genetic, and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, SE5 8AF, London, United Kingdom
    Am J Psychiatry 167:555-64. 2010
  5. doi request reprint Differential efficacy of escitalopram and nortriptyline on dimensional measures of depression
    Rudolf Uher
    Institute of Psychiatry, King s College London, 16 De Crespigny Park, SE5 8AF, London, UK
    Br J Psychiatry 194:252-9. 2009
  6. doi request reprint Changes in body weight during pharmacological treatment of depression
    Rudolf Uher
    Institute of Psychiatry, King s College London, London, UK
    Int J Neuropsychopharmacol 14:367-75. 2011
  7. doi request reprint Genetic predictors of response to antidepressants in the GENDEP project
    Rudolf Uher
    MRC Social Genetic and Developmental Psychiatry Center, Institute of Psychiatry, King s College London, London, UK
    Pharmacogenomics J 9:225-33. 2009
  8. doi request reprint Melancholic, atypical and anxious depression subtypes and outcome of treatment with escitalopram and nortriptyline
    Rudolf Uher
    MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, United Kingdom
    J Affect Disord 132:112-20. 2011
  9. doi request reprint Personality and the bipolar spectrum: normative and classification data for the Eysenck Personality Questionnaire-Revised
    Luke D Smillie
    Department of Psychology, Goldsmiths, University of London, London, UK
    Compr Psychiatry 50:48-53. 2009
  10. doi request reprint The Bipolar Association Case-Control Study (BACCS) and meta-analysis: No association with the 5,10-Methylenetetrahydrofolate reductase gene and bipolar disorder
    Sarah Cohen-Woods
    Institute of Psychiatry, King s College London, MRC SGDP Centre, London, UK
    Am J Med Genet B Neuropsychiatr Genet 153:1298-304. 2010

Collaborators

Detail Information

Publications27

  1. ncbi request reprint Prevalence of chronic disabling fatigue in children and adolescents
    Anne Farmer
    MRC Social, Genetic, Developmental Psychiatric Research Centre, Institute of Psychiatry, London, UK
    Br J Psychiatry 184:477-81. 2004
    ..The epidemiology of chronic fatiguing illnesses in young people is poorly understood...
  2. pmc The definition of disabling fatigue in children and adolescents
    Tom Fowler
    Department of Psychological Medicine, Wales College of Medicine, Cardiff University, UK
    BMC Fam Pract 6:33. 2005
    ....
  3. doi request reprint Moderation of antidepressant response by the serotonin transporter gene
    Patricia Huezo-Diaz
    Institute of Psychiatry, King s College London, UK
    Br J Psychiatry 195:30-8. 2009
    ..We hypothesised that the pharmacogenetic effect of 5-HTTLPR is modulated by gender, age and other variants in the serotonin transporter gene...
  4. doi request reprint Genome-wide pharmacogenetics of antidepressant response in the GENDEP project
    Rudolf Uher
    Medical Research Council Social, Genetic, and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, SE5 8AF, London, United Kingdom
    Am J Psychiatry 167:555-64. 2010
    ..The authors performed a genome-wide association analysis of improvement of depression severity with two antidepressant drugs...
  5. doi request reprint Differential efficacy of escitalopram and nortriptyline on dimensional measures of depression
    Rudolf Uher
    Institute of Psychiatry, King s College London, 16 De Crespigny Park, SE5 8AF, London, UK
    Br J Psychiatry 194:252-9. 2009
    ..Tricyclic antidepressants and serotonin reuptake inhibitors are considered to be equally effective, but differences may have been obscured by internally inconsistent measurement scales and inefficient statistical analyses...
  6. doi request reprint Changes in body weight during pharmacological treatment of depression
    Rudolf Uher
    Institute of Psychiatry, King s College London, London, UK
    Int J Neuropsychopharmacol 14:367-75. 2011
    ..While treatment with nortriptyline may be recommended in underweight subjects with typical neurovegetative symptoms, escitalopram is a suitable alternative for subjects at risk of weight gain...
  7. doi request reprint Genetic predictors of response to antidepressants in the GENDEP project
    Rudolf Uher
    MRC Social Genetic and Developmental Psychiatry Center, Institute of Psychiatry, King s College London, London, UK
    Pharmacogenomics J 9:225-33. 2009
    ..The single marker associations explained only a small proportion of variance in response to antidepressants, indicating a need for a multivariate approach to prediction...
  8. doi request reprint Melancholic, atypical and anxious depression subtypes and outcome of treatment with escitalopram and nortriptyline
    Rudolf Uher
    MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, United Kingdom
    J Affect Disord 132:112-20. 2011
    ..To investigate whether subtypes of depression predict differential outcomes of treatment with selective serotonin-reuptake inhibitor (SSRI) and a tricyclic antidepressant in major depression...
  9. doi request reprint Personality and the bipolar spectrum: normative and classification data for the Eysenck Personality Questionnaire-Revised
    Luke D Smillie
    Department of Psychology, Goldsmiths, University of London, London, UK
    Compr Psychiatry 50:48-53. 2009
    ..The Eysenck Personality Questionnaire-Revised. Sevenoaks: UK; Hodder & Stoughton, 1992)...
  10. doi request reprint The Bipolar Association Case-Control Study (BACCS) and meta-analysis: No association with the 5,10-Methylenetetrahydrofolate reductase gene and bipolar disorder
    Sarah Cohen-Woods
    Institute of Psychiatry, King s College London, MRC SGDP Centre, London, UK
    Am J Med Genet B Neuropsychiatr Genet 153:1298-304. 2010
    ..We also performed a meta-analysis of our own, and all published data, and report no evidence for association. Our findings suggest that the MTHFR C677T polymorphism is not involved in the genetic etiology of clinically significant BD...
  11. doi request reprint Early and delayed onset of response to antidepressants in individual trajectories of change during treatment of major depression: a secondary analysis of data from the Genome-Based Therapeutic Drugs for Depression (GENDEP) study
    Rudolf Uher
    MRC Social, Genetic and Developmental Psychiatry Research Centre, Institute of Psychiatry, King s College London, United Kingdom, London, UK
    J Clin Psychiatry 72:1478-84. 2011
    ..We explore the individual trajectories of relative change in depression severity to establish what proportion of individuals experience early and late onset of improvement...
  12. doi request reprint Depression Case Control (DeCC) Study fails to support involvement of the muscarinic acetylcholine receptor M2 (CHRM2) gene in recurrent major depressive disorder
    Sarah Cohen-Woods
    MRC SGDP Centre, Institute of Psychiatry, King s College London, London, UK
    Hum Mol Genet 18:1504-9. 2009
    ..It is possible our failure to replicate may be a consequence of differences in definition of the MDD phenotype and/or ethnic differences...
  13. doi request reprint Replication study and meta-analysis in European samples supports association of the 3p21.1 locus with bipolar disorder
    Evangelos Vassos
    MRC SGDP Centre, Institute of Psychiatry, King s College London, London, United Kingdom
    Biol Psychiatry 72:645-50. 2012
    ..Subsequent studies have suggested that this is also a risk locus for other psychiatric phenotypes, including major depression and schizophrenia...
  14. doi request reprint Medical disorders in people with recurrent depression
    Anne Farmer
    Medical Research Council, Social Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, De Crespigny Park, London, UK
    Br J Psychiatry 192:351-5. 2008
    ..Few studies have examined the rates of physical disorders in those with recurrent depression...
  15. doi request reprint Adverse reactions to antidepressants
    Rudolf Uher
    P080 SGDP, Institute of Psychiatry, King s College London, London SE5 8AF, UK
    Br J Psychiatry 195:202-10. 2009
    ..Adverse drug reactions are important determinants of non-adherence to antidepressant treatment, but their assessment is complicated by overlap with depressive symptoms and lack of reliable self-report measures...
  16. pmc Male-biased autosomal effect of 16p13.11 copy number variation in neurodevelopmental disorders
    Maria Tropeano
    MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, London, UK
    PLoS ONE 8:e61365. 2013
    ..11 represent incompletely penetrant pathogenic mutations that predispose to a range of neurodevelopmental disorders, and suggest a sex-limited effect on the penetrance of the pathological phenotypes at the 16p13.11 locus...
  17. pmc The Depression Network (DeNT) Study: methodology and sociodemographic characteristics of the first 470 affected sibling pairs from a large multi-site linkage genetic study
    Anne Farmer
    Medical Research Council Social Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, London, UK
    BMC Psychiatry 4:42. 2004
    ..This study presents the method and socio-demographic details of the first 470 affected sibling pairs recruited from 8 different sites in Europe and the United States of America...
  18. pmc Genetic predictors of response to serotonergic and noradrenergic antidepressants in major depressive disorder: a genome-wide analysis of individual-level data and a meta-analysis
    Katherine E Tansey
    Institute of Psychiatry, King s College London, London, UK
    PLoS Med 9:e1001326. 2012
    ..This study aims to test the hypothesis that common genetic variants can predict response to antidepressants in a clinically meaningful way...
  19. doi request reprint Association of the dystrobrevin binding protein 1 gene (DTNBP1) in a bipolar case-control study (BACCS)
    Darya Gaysina
    MRC SGDP Centre, Institute of Psychiatry, King s College London, London, UK
    Am J Med Genet B Neuropsychiatr Genet 150:836-44. 2009
    ....
  20. ncbi request reprint A pilot study of positive mood induction in euthymic bipolar subjects compared with healthy controls
    Anne Farmer
    MRC Social, Genetic and Developmental Psychiatry Research Centre, Institute of Psychiatry, Camberwell, London, UK
    Psychol Med 36:1213-8. 2006
    ..This pilot study evaluates the Go task in a reward paradigm as a method for inducing a happy mood state and compares the response of euthymic bipolar subjects and healthy controls...
  21. ncbi request reprint The genetics of bipolar affective disorder
    Anne Farmer
    MRC SGDP Centre, Institute of Psychiatry, Camberwell, London, UK
    Curr Opin Psychiatry 20:8-12. 2007
    ..Molecular genetic studies of bipolar affective disorder are beginning to show some positive and reproducible findings. The most relevant of these will be reviewed...
  22. pmc OPCRIT+: an electronic system for psychiatric diagnosis and data collection in clinical and research settings
    James Rucker
    MRC Social, Genetic and Development Psychiatry Centre, Institute of Psychiatry, King s College London, 16 De Crespigny Park, London SE5 8AF, UK
    Br J Psychiatry 199:151-5. 2011
    ..Aims To develop a data collection and diagnostic application that can be used across a broad range of clinical and research settings...
  23. ncbi request reprint The relationship of fatigue to mental and physical health in a community sample
    Richard J Williamson
    Social, Genetic, Developmental Psychiatry Research, Institute of Psychiatry, PO80, 16 De Crespigny Park, Denmark Hill London SE5 8AF, UK
    Soc Psychiatry Psychiatr Epidemiol 40:126-32. 2005
    ..The present study seeks to differentiate between fatigue and depression/anxiety and to investigate the familiality/heritability of fatigue using sib-pairs...
  24. ncbi request reprint Response style, interpersonal difficulties and social functioning in major depressive disorder
    Dominic Lam
    Institute of Psychiatry, King s College London, De Crespigny Park, London SE5 8AF, UK
    J Affect Disord 75:279-83. 2003
    ....
  25. ncbi request reprint Genome-wide linkage analysis of a composite index of neuroticism and mood-related scales in extreme selected sibships
    Matthew W Nash
    MRC Social, Genetic and Developmental Psychiatry Research Centre, Section of Epidemiology, Institute of Psychiatry, King s College, London, UK
    Hum Mol Genet 13:2173-82. 2004
    ..2) around 64 cM (43-70 cM) near marker D1S2892 and another on chromosome 6p (LOD 2.7) around 47 cM (34-63 cM) near marker D6S1610. Further exploratory sex-specific analyses suggested that these QTLs might have sex-limited effects...
  26. pmc Up-beat UK: a programme of research into the relationship between coronary heart disease and depression in primary care patients
    Andre Tylee
    Health Services and Population Research Dept, Institute of Psychiatry, King s College London, UK
    BMC Fam Pract 12:38. 2011
    ..We aim to explore the relationship between coronary heart disease and depression in a primary care population and to develop an intervention for patients with coronary heart disease and depression...
  27. ncbi request reprint A sib-pair study of the Temperament and Character Inventory scales in major depression
    Anne Farmer
    Medical Research Council, Social Genetic and Developmental Psychiatry Research Centre, Institute of Psychiatry, London, England
    Arch Gen Psychiatry 60:490-6. 2003
    ..A sib-pair method has been used to examine the familiality of the 7 scales of the Temperament and Character Inventory (TCI) and whether this could be related to the genetic vulnerability to develop depression...