Heather Julia Ellis

Summary

Affiliation: King's College London
Country: UK

Publications

  1. doi request reprint Antibodies to wheat high-molecular-weight glutenin subunits in patients with celiac disease
    H Julia Ellis
    Division of Diabetes and Nutritional Sciences, King s College London, London, UK
    Int Arch Allergy Immunol 159:428-34. 2012
  2. doi request reprint Should coeliac sufferers be allowed their oats?
    Heather Julia Ellis
    Division of Nutritional Sciences, King s College London, London, England, UK
    Eur J Gastroenterol Hepatol 20:492-3. 2008
  3. pmc Investigation of the putative immunodominant T cell epitopes in coeliac disease
    H J Ellis
    Gastroenterology Unit, Rayne Institute KCL, St Thomas Hospital, London, UK
    Gut 52:212-7. 2003
  4. ncbi request reprint In vivo gluten challenge in celiac disease
    H J Ellis
    Gastroenterology Unit, The Rayne Institute, St Thomas Hospital, London, United Kingdom
    Can J Gastroenterol 15:243-7. 2001
  5. ncbi request reprint Characterizing one of the DQ2 candidate epitopes in coeliac disease: A-gliadin 51-70 toxicity assessed using an organ culture system
    Susi Martucci
    Gastroenterology Department, Rayne Institute KCL, St Thomas Hospital, London, UK
    Eur J Gastroenterol Hepatol 15:1293-8. 2003
  6. pmc CTLA-4/CD28 gene region is associated with genetic susceptibility to coeliac disease in UK families
    A L King
    J Med Genet 39:51-4. 2002
  7. ncbi request reprint Analysis of candidate genes on chromosome 19 in coeliac disease: an association study of the KIR and LILR gene clusters
    S J Moodie
    Gastroenteroly Unit, GKT, The Rayne Institute, St Trhomas Hospital, London, UK
    Eur J Immunogenet 29:287-91. 2002
  8. ncbi request reprint Coeliac disease: follow-up linkage study provides further support for existence of a susceptibility locus on chromosome 11p11
    A L King
    Gastroenterology Unit, GKT, The Rayne Institute, St. Thomas' Hospital, London, UK
    Ann Hum Genet 65:377-86. 2001
  9. pmc Coeliac disease: in vivo toxicity of the putative immunodominant epitope
    J S Fraser
    Gastroenterology Department, Rayne Institute KCL, St Thomas Hospital, London SE1 7EH, UK
    Gut 52:1698-702. 2003
  10. pmc Human lymphocyte stimulation with pouchitis flora is greater than with flora from a healthy pouch but is suppressed by metronidazole
    A J G Bell
    Department of Gastroenterology, The Rayne Institute, 4th Floor Lambeth Wing, St Thomas Hospital, Lambeth Palace Road, London SE1 7EH, UK
    Gut 53:1801-5. 2004

Collaborators

  • Alastair Forbes
  • P J Ciclitira
  • J S Fraser
  • S J Moodie
  • A L King
  • D Curtis
  • A J G Bell
  • Susi Martucci
  • A M Dearlove
  • R Kumar
  • R J Nicholls
  • E L Pollock
  • Gino Roberto Corazza
  • Federico Biagi
  • Jocelyn Sophie Fraser
  • H Wieser
  • W Engel
  • R W Vaughan
  • P J Norman
  • E Reid
  • S Rosen-Bronson
  • A Lumsden
  • G W Laurie

Detail Information

Publications11

  1. doi request reprint Antibodies to wheat high-molecular-weight glutenin subunits in patients with celiac disease
    H Julia Ellis
    Division of Diabetes and Nutritional Sciences, King s College London, London, UK
    Int Arch Allergy Immunol 159:428-34. 2012
    ..The high-molecular-weight (HMW) glutenin subunits (GS)-1Dy10 are toxic for patients with celiac disease (CD). This study aimed to assess whether CD patients mount a serological response to HMW-GS-1Dy10...
  2. doi request reprint Should coeliac sufferers be allowed their oats?
    Heather Julia Ellis
    Division of Nutritional Sciences, King s College London, London, England, UK
    Eur J Gastroenterol Hepatol 20:492-3. 2008
    ..Oats could form a potentially useful part of a gluten-free diet, but patients require careful advice and monitoring, backed by robust gluten-assay techniques...
  3. pmc Investigation of the putative immunodominant T cell epitopes in coeliac disease
    H J Ellis
    Gastroenterology Unit, Rayne Institute KCL, St Thomas Hospital, London, UK
    Gut 52:212-7. 2003
    ..Deamidation by tissue transglutaminase (tTG) of the glutamine (Q) at position 65 to glutamic acid (E) is essential for T cell stimulation...
  4. ncbi request reprint In vivo gluten challenge in celiac disease
    H J Ellis
    Gastroenterology Unit, The Rayne Institute, St Thomas Hospital, London, United Kingdom
    Can J Gastroenterol 15:243-7. 2001
    ..This could result in an abnormal presentation to the immune system, triggering a pathogenic rather than a tolerogenic response...
  5. ncbi request reprint Characterizing one of the DQ2 candidate epitopes in coeliac disease: A-gliadin 51-70 toxicity assessed using an organ culture system
    Susi Martucci
    Gastroenterology Department, Rayne Institute KCL, St Thomas Hospital, London, UK
    Eur J Gastroenterol Hepatol 15:1293-8. 2003
    ..To investigate, using an organ culture system, in-vitro toxicity of region 51-70 of A-gliadin (SQQPYLQLQPFPQPQLPYSQ), a peptide overlapping some of the sequences recently characterized as DQ2-restricted T-cell epitopes in coeliac disease...
  6. pmc CTLA-4/CD28 gene region is associated with genetic susceptibility to coeliac disease in UK families
    A L King
    J Med Genet 39:51-4. 2002
  7. ncbi request reprint Analysis of candidate genes on chromosome 19 in coeliac disease: an association study of the KIR and LILR gene clusters
    S J Moodie
    Gastroenteroly Unit, GKT, The Rayne Institute, St Trhomas Hospital, London, UK
    Eur J Immunogenet 29:287-91. 2002
    ..A transmission disequilibrium test also found no association of the A and B KIR haplotypes or the LILRA3 gene deletion with coeliac disease...
  8. ncbi request reprint Coeliac disease: follow-up linkage study provides further support for existence of a susceptibility locus on chromosome 11p11
    A L King
    Gastroenterology Unit, GKT, The Rayne Institute, St. Thomas' Hospital, London, UK
    Ann Hum Genet 65:377-86. 2001
    ..6 at D11S914 on chromosome 11p11. This marker maps to a position implicated in one of the two previous genome scans and taken together these results provide strong support for the existence of a susceptibility locus in this region...
  9. pmc Coeliac disease: in vivo toxicity of the putative immunodominant epitope
    J S Fraser
    Gastroenterology Department, Rayne Institute KCL, St Thomas Hospital, London SE1 7EH, UK
    Gut 52:1698-702. 2003
    ..We wished to investigate whether a peptide corresponding to residues 56-75 of alpha-gliadins exacerbates coeliac disease in vivo...
  10. pmc Human lymphocyte stimulation with pouchitis flora is greater than with flora from a healthy pouch but is suppressed by metronidazole
    A J G Bell
    Department of Gastroenterology, The Rayne Institute, 4th Floor Lambeth Wing, St Thomas Hospital, Lambeth Palace Road, London SE1 7EH, UK
    Gut 53:1801-5. 2004
    ..Using bacteria from patients the authors sought evidence for the presence rather than the identity of a pathogenic species in pouchitis, and for its absence in healthy pouches by the differential effect on lymphocyte proliferation...
  11. ncbi request reprint Human genome search in celiac disease using gliadin cDNA as probe
    R Kumar
    Department of Cell Biology, University of Virginia, Charlottesville, VA 22908, USA
    J Mol Biol 300:1155-67. 2000
    ..Glutamine to glutamic acid or other mutation within such epitopes followed by injury or infection-related release could explain enhanced disease susceptibility in affected families...