Heather Julia Ellis

Summary

Affiliation: King's College London
Country: UK

Publications

  1. ncbi Antibodies to wheat high-molecular-weight glutenin subunits in patients with celiac disease
    H Julia Ellis
    Division of Diabetes and Nutritional Sciences, King s College London, London, UK
    Int Arch Allergy Immunol 159:428-34. 2012
  2. ncbi Should coeliac sufferers be allowed their oats?
    Heather Julia Ellis
    Division of Nutritional Sciences, King s College London, London, England, UK
    Eur J Gastroenterol Hepatol 20:492-3. 2008
  3. ncbi Investigation of the putative immunodominant T cell epitopes in coeliac disease
    H J Ellis
    Gastroenterology Unit, Rayne Institute KCL, St Thomas Hospital, London, UK
    Gut 52:212-7. 2003
  4. ncbi In vivo gluten challenge in celiac disease
    H J Ellis
    Gastroenterology Unit, The Rayne Institute, St Thomas Hospital, London, United Kingdom
    Can J Gastroenterol 15:243-7. 2001
  5. ncbi Characterizing one of the DQ2 candidate epitopes in coeliac disease: A-gliadin 51-70 toxicity assessed using an organ culture system
    Susi Martucci
    Gastroenterology Department, Rayne Institute (KCL, St Thomas' Hospital, London, UK
    Eur J Gastroenterol Hepatol 15:1293-8. 2003
  6. ncbi CTLA-4/CD28 gene region is associated with genetic susceptibility to coeliac disease in UK families
    A L King
    J Med Genet 39:51-4. 2002
  7. ncbi Analysis of candidate genes on chromosome 19 in coeliac disease: an association study of the KIR and LILR gene clusters
    S J Moodie
    Gastroenteroly Unit, GKT, The Rayne Institute, St Trhomas Hospital, London, UK
    Eur J Immunogenet 29:287-91. 2002
  8. ncbi Coeliac disease: follow-up linkage study provides further support for existence of a susceptibility locus on chromosome 11p11
    A L King
    Gastroenterology Unit, GKT, The Rayne Institute, St. Thomas' Hospital, London, UK
    Ann Hum Genet 65:377-86. 2001
  9. ncbi Coeliac disease: in vivo toxicity of the putative immunodominant epitope
    J S Fraser
    Gastroenterology Department, Rayne Institute (KCL, St Thomas' Hospital, London SE1 7EH, UK
    Gut 52:1698-702. 2003
  10. ncbi Human lymphocyte stimulation with pouchitis flora is greater than with flora from a healthy pouch but is suppressed by metronidazole
    A J G Bell
    Department of Gastroenterology, The Rayne Institute, 4th Floor Lambeth Wing, St Thomas' Hospital, Lambeth Palace Road, London SE1 7EH, UK
    Gut 53:1801-5. 2004

Collaborators

  • Alastair Forbes
  • P J Ciclitira
  • J S Fraser
  • S J Moodie
  • A L King
  • D Curtis
  • A J G Bell
  • Susi Martucci
  • A M Dearlove
  • R Kumar
  • R J Nicholls
  • Federico Biagi
  • W Engel
  • Gino Roberto Corazza
  • Jocelyn Sophie Fraser
  • E L Pollock
  • H Wieser
  • E Reid
  • P J Norman
  • R W Vaughan
  • S Rosen-Bronson
  • A Lumsden
  • G W Laurie

Detail Information

Publications11

  1. ncbi Antibodies to wheat high-molecular-weight glutenin subunits in patients with celiac disease
    H Julia Ellis
    Division of Diabetes and Nutritional Sciences, King s College London, London, UK
    Int Arch Allergy Immunol 159:428-34. 2012
    ..The high-molecular-weight (HMW) glutenin subunits (GS)-1Dy10 are toxic for patients with celiac disease (CD). This study aimed to assess whether CD patients mount a serological response to HMW-GS-1Dy10...
  2. ncbi Should coeliac sufferers be allowed their oats?
    Heather Julia Ellis
    Division of Nutritional Sciences, King s College London, London, England, UK
    Eur J Gastroenterol Hepatol 20:492-3. 2008
    ..Oats could form a potentially useful part of a gluten-free diet, but patients require careful advice and monitoring, backed by robust gluten-assay techniques...
  3. ncbi Investigation of the putative immunodominant T cell epitopes in coeliac disease
    H J Ellis
    Gastroenterology Unit, Rayne Institute KCL, St Thomas Hospital, London, UK
    Gut 52:212-7. 2003
    ..Deamidation by tissue transglutaminase (tTG) of the glutamine (Q) at position 65 to glutamic acid (E) is essential for T cell stimulation...
  4. ncbi In vivo gluten challenge in celiac disease
    H J Ellis
    Gastroenterology Unit, The Rayne Institute, St Thomas Hospital, London, United Kingdom
    Can J Gastroenterol 15:243-7. 2001
    ..This could result in an abnormal presentation to the immune system, triggering a pathogenic rather than a tolerogenic response...
  5. ncbi Characterizing one of the DQ2 candidate epitopes in coeliac disease: A-gliadin 51-70 toxicity assessed using an organ culture system
    Susi Martucci
    Gastroenterology Department, Rayne Institute (KCL, St Thomas' Hospital, London, UK
    Eur J Gastroenterol Hepatol 15:1293-8. 2003
    ..The lack of response in two of ten subjects suggests that this epitope may not be relevant in all cases of coeliac disease...
  6. ncbi CTLA-4/CD28 gene region is associated with genetic susceptibility to coeliac disease in UK families
    A L King
    J Med Genet 39:51-4. 2002
  7. ncbi Analysis of candidate genes on chromosome 19 in coeliac disease: an association study of the KIR and LILR gene clusters
    S J Moodie
    Gastroenteroly Unit, GKT, The Rayne Institute, St Trhomas Hospital, London, UK
    Eur J Immunogenet 29:287-91. 2002
    ..A transmission disequilibrium test also found no association of the A and B KIR haplotypes or the LILRA3 gene deletion with coeliac disease...
  8. ncbi Coeliac disease: follow-up linkage study provides further support for existence of a susceptibility locus on chromosome 11p11
    A L King
    Gastroenterology Unit, GKT, The Rayne Institute, St. Thomas' Hospital, London, UK
    Ann Hum Genet 65:377-86. 2001
    ..6 at D11S914 on chromosome 11p11. This marker maps to a position implicated in one of the two previous genome scans and taken together these results provide strong support for the existence of a susceptibility locus in this region...
  9. ncbi Coeliac disease: in vivo toxicity of the putative immunodominant epitope
    J S Fraser
    Gastroenterology Department, Rayne Institute (KCL, St Thomas' Hospital, London SE1 7EH, UK
    Gut 52:1698-702. 2003
    ..CONCLUSION: We have confirmed that the putative immunodominant epitope, a peptide corresponding to residues 56-75 of alpha-gliadins, exacerbates coeliac disease in vivo...
  10. ncbi Human lymphocyte stimulation with pouchitis flora is greater than with flora from a healthy pouch but is suppressed by metronidazole
    A J G Bell
    Department of Gastroenterology, The Rayne Institute, 4th Floor Lambeth Wing, St Thomas' Hospital, Lambeth Palace Road, London SE1 7EH, UK
    Gut 53:1801-5. 2004
    ..CONCLUSIONS: These results strongly support a bacterial aetiology for pouchitis...
  11. ncbi Human genome search in celiac disease using gliadin cDNA as probe
    R Kumar
    Department of Cell Biology, University of Virginia, Charlottesville, VA 22908, USA
    J Mol Biol 300:1155-67. 2000
    ..Glutamine to glutamic acid or other mutation within such epitopes followed by injury or infection-related release could explain enhanced disease susceptibility in affected families...