F A Drobniewski

Summary

Affiliation: King's College London
Country: UK

Publications

  1. pmc Silent nucleotide polymorphisms and a phylogeny for Mycobacterium tuberculosis
    Lucy Baker
    Health Protection Agency, London, United Kingdom
    Emerg Infect Dis 10:1568-77. 2004
  2. ncbi Multidrug-resistant tuberculosis in Russia: clinical characteristics, analysis of second-line drug resistance and development of standardized therapy
    Y Balabanova
    Samara TB Service, Samara Oblast Dispensary, Samara, Russia
    Eur J Clin Microbiol Infect Dis 24:136-9. 2005
  3. ncbi The diagnosis and management of multiple-drug-resistant-tuberculosis at the beginning of the new millenium
    F A Drobniewski
    Department of Infection, Guy s King s and St Thomas Medical College, King s College London, UK
    Int J Infect Dis 6:S21-31. 2002
  4. ncbi Increasing trends in HIV and TB rates in Odessa and the Ukraine
    F Drobniewski
    HPA Mycobacterium Reference Unit and Department of Infectious Diseases, King s College Hospital Dulwich, East Dulwich Grove, London SE22 8QF, UK
    Int J STD AIDS 16:374-8. 2005
  5. ncbi Drug-resistant tuberculosis, clinical virulence, and the dominance of the Beijing strain family in Russia
    Francis Drobniewski
    HPA Mycobacterium Reference Unit, Department of Microbiology and Infection, Guy s King s and St Thomas Medical School, London, England
    JAMA 293:2726-31. 2005
  6. ncbi Clinical features, diagnosis, and management of multiple drug-resistant tuberculosis since 2002
    Francis Drobniewski
    Mycobacterium Reference Unit, Department of Microbiology and Infection, Guy s, King s, and St Thomas Medical School, King s College Hospital Dulwich, London, UK
    Curr Opin Pulm Med 10:211-7. 2004
  7. ncbi Tuberculosis, HIV seroprevalence and intravenous drug abuse in prisoners
    F A Drobniewski
    HPA National Mycobacterium Reference Unit, Dept of Microbiology and Infection, King s College Hospital Dulwich, East Dulwich Grove, London SE22 8QF, UK
    Eur Respir J 26:298-304. 2005
  8. pmc Evaluation and utilization as a public health tool of a national molecular epidemiological tuberculosis outbreak database within the United Kingdom from 1997 to 2001
    F A Drobniewski
    Public Health Laboratory Service Mycobacterium Reference Unit and Regional Center for Mycobacteriology, Department of Infection, GKT School of Medicine, King s College Hospital, Dulwich, London SE22 8QF, United Kingdom
    J Clin Microbiol 41:1861-8. 2003
  9. ncbi Modern laboratory diagnosis of tuberculosis
    F A Drobniewski
    PHLS Mycobacterium Reference Unit and Department of Infection, Guy s King s and St Thomas Medical College, King s College Hospital Dulwich London, UK
    Lancet Infect Dis 3:141-7. 2003
  10. ncbi Tuberculosis and the role of war in the modern era
    F A Drobniewski
    Dulwich Public Health Laboratory, Guy s King s and St Thomas Medical School, King s College Hospital Dulwich, London, UK
    Int J Tuberc Lung Dis 4:1120-5. 2000

Collaborators

Detail Information

Publications57

  1. pmc Silent nucleotide polymorphisms and a phylogeny for Mycobacterium tuberculosis
    Lucy Baker
    Health Protection Agency, London, United Kingdom
    Emerg Infect Dis 10:1568-77. 2004
    ..tuberculosis strains and provides a unifying framework for both epidemiologic and evolutionary analysis of M. tuberculosis populations...
  2. ncbi Multidrug-resistant tuberculosis in Russia: clinical characteristics, analysis of second-line drug resistance and development of standardized therapy
    Y Balabanova
    Samara TB Service, Samara Oblast Dispensary, Samara, Russia
    Eur J Clin Microbiol Infect Dis 24:136-9. 2005
    ..4%), and prothionamide (1.5%). The results of the study indicate it is possible to develop a standard, effective, clinical treatment regimen using ethambutol, pyrazinamide, prothionamide, a fluoroquinolone and amikacin...
  3. ncbi The diagnosis and management of multiple-drug-resistant-tuberculosis at the beginning of the new millenium
    F A Drobniewski
    Department of Infection, Guy s King s and St Thomas Medical College, King s College London, UK
    Int J Infect Dis 6:S21-31. 2002
    ..Clearly the most important therapeutic modality for MDRTB is to treat drug-sensitive TB correctly in the first instance and prevent the emergence of resistant TB...
  4. ncbi Increasing trends in HIV and TB rates in Odessa and the Ukraine
    F Drobniewski
    HPA Mycobacterium Reference Unit and Department of Infectious Diseases, King s College Hospital Dulwich, East Dulwich Grove, London SE22 8QF, UK
    Int J STD AIDS 16:374-8. 2005
    ..Significant effort is needed for the effective control of these two outbreaks to prevent high levels of morbidity and mortality from these diseases...
  5. ncbi Drug-resistant tuberculosis, clinical virulence, and the dominance of the Beijing strain family in Russia
    Francis Drobniewski
    HPA Mycobacterium Reference Unit, Department of Microbiology and Infection, Guy s King s and St Thomas Medical School, London, England
    JAMA 293:2726-31. 2005
    ..Tuberculosis and multidrug-resistant tuberculosis is a serious public health problem in Russia...
  6. ncbi Clinical features, diagnosis, and management of multiple drug-resistant tuberculosis since 2002
    Francis Drobniewski
    Mycobacterium Reference Unit, Department of Microbiology and Infection, Guy s, King s, and St Thomas Medical School, King s College Hospital Dulwich, London, UK
    Curr Opin Pulm Med 10:211-7. 2004
    ..Multiple drug-resistant tuberculosis is increasing globally, particularly in Eastern Europe. This review summarizes advances in our understanding of the epidemiology, diagnosis, and treatment of MDRTB in 2002-2003...
  7. ncbi Tuberculosis, HIV seroprevalence and intravenous drug abuse in prisoners
    F A Drobniewski
    HPA National Mycobacterium Reference Unit, Dept of Microbiology and Infection, King s College Hospital Dulwich, East Dulwich Grove, London SE22 8QF, UK
    Eur Respir J 26:298-304. 2005
    ..Prisons are major drivers of the tuberculosis and HIV epidemics. Novel strategies are needed to reduce the spread of blood borne diseases, particularly in intravenous drug users...
  8. pmc Evaluation and utilization as a public health tool of a national molecular epidemiological tuberculosis outbreak database within the United Kingdom from 1997 to 2001
    F A Drobniewski
    Public Health Laboratory Service Mycobacterium Reference Unit and Regional Center for Mycobacteriology, Department of Infection, GKT School of Medicine, King s College Hospital, Dulwich, London SE22 8QF, United Kingdom
    J Clin Microbiol 41:1861-8. 2003
    ..The patients were multiethnic, born mainly in the United Kingdom, and included professionals, individuals from the music industry, intravenous drug abusers, and prisoners...
  9. ncbi Modern laboratory diagnosis of tuberculosis
    F A Drobniewski
    PHLS Mycobacterium Reference Unit and Department of Infection, Guy s King s and St Thomas Medical College, King s College Hospital Dulwich London, UK
    Lancet Infect Dis 3:141-7. 2003
    ..It proposes operational criteria for a modern diagnostic service in the UK (as a model of a low-incidence country) and explores some of the economic issues surrounding the use of these techniques...
  10. ncbi Tuberculosis and the role of war in the modern era
    F A Drobniewski
    Dulwich Public Health Laboratory, Guy s King s and St Thomas Medical School, King s College Hospital Dulwich, London, UK
    Int J Tuberc Lung Dis 4:1120-5. 2000
    ..Tuberculosis (TB) remains a major global health problem; historically, major wars have increased TB notifications. This study evaluated whether modern conflicts worldwide affected TB notifications between 1975 and 1995...
  11. pmc Differentiation of Mycobacterium tuberculosis complex and nontuberculous mycobacterial liquid cultures by using peptide nucleic acid-fluorescence In situ hybridization probes
    F A Drobniewski
    PHLS Mycobacterium Reference Unit, Department of Microbiology, Dulwich Public Health Laboratory, Guy s King s and St Thomas Medical School, Dulwich Hospital, London SE22 8QF, United Kingdom
    J Clin Microbiol 38:444-7. 2000
    ..5%) nontuberculous cultures were correctly identified (including one mixed culture). Five isolates yielded no reaction with either probe and were identified as Mycobacterium xenopi, Mycobacterium fortuitum, or Mycobacterium flavescens...
  12. pmc Rifampin- and multidrug-resistant tuberculosis in Russian civilians and prison inmates: dominance of the beijing strain family
    Francis Drobniewski
    Guy s King s amd St Thomas Medical School, King s College Hospital, London, United Kingdom
    Emerg Infect Dis 8:1320-6. 2002
    ..5%) were rifampin resistant. Rifampin-resistant Beijing isolates are dominant within the patient population, especially among prisoners, and threaten treatment programs...
  13. pmc Comparison of three molecular assays for rapid detection of rifampin resistance in Mycobacterium tuberculosis
    S A Watterson
    Public Health Laboratory Service Mycobacterium Reference Unit, Department of Microbiology, King s College School of Medicine and Dentistry, King s College Hospital Dulwich, London, United Kingdom
    J Clin Microbiol 36:1969-73. 1998
    ..7 and 100%), respectively. For the 21 isolates submitted by clinicians, both assays correlated 100% with routine testing...
  14. ncbi Molecular epidemiology and prevalence of mutations conferring rifampicin and isoniazid resistance in Mycobacterium tuberculosis strains from the southern Ukraine
    V V Nikolayevskyy
    HPA Mycobacterium Reference Unit, Institute of Cell and Molecular Sciences, Clinical TB and HIV Group, Queen Mary s School of Medicine and Dentistry, London, UK
    Clin Microbiol Infect 13:129-38. 2007
    ..4% vs. 45.7%; RR 1.74; 95% CI 1.17-2.57), suggesting that this group may be responsible for rapid transmission of MDR TB in the southern Ukraine...
  15. pmc Evaluation of a bacteriophage-based assay (phage amplified biologically assay) as a rapid screen for resistance to isoniazid, ethambutol, streptomycin, pyrazinamide, and ciprofloxacin among clinical isolates of Mycobacterium tuberculosis
    I J Eltringham
    PHLS Mycobacterium Reference Unit, Dulwich PHL and Department of Microbiology, King s College School of Medicine and Dentistry, King s College Hospital Dulwich, London SE22 8QF, United Kingdom
    J Clin Microbiol 37:3528-32. 1999
    ..We believe that this low-cost assay may have widespread applicability for the rapid screening of drug resistance in M. tuberculosis isolates, especially in developing countries...
  16. ncbi The use of macroarrays for the identification of MDR Mycobacterium tuberculosis
    T J Brown
    Health Protection Agency Mycobacterium Reference Unit, Kings College Hospital Dulwich, East Dulwich Grove, London SE22 8QF, UK
    J Microbiol Methods 65:294-300. 2006
    ..All mutations within katG and mabA-inhA were correctly identified. We conclude that this low cost, rapid system can usefully detect the mutations associated with the vast majority of MDR-Mtb...
  17. pmc Molecular analysis of isoniazid-resistant Mycobacterium tuberculosis isolates from England and Wales reveals the phylogenetic significance of the ahpC -46A polymorphism
    L V Baker
    HPA Mycobacterium Reference Unit, Department of Microbiology, Guy s, King s and St Thomas School of Medicine, King s College Hospital, East Dulwich Grove, London SE22 8QF, United Kingdom
    Antimicrob Agents Chemother 49:1455-64. 2005
    ..Analysis of the oxyR-ahpC intergenic region, although phylogenetically interesting, does not contribute significantly to further identification of isoniazid-resistant isolates...
  18. pmc Specificity of IS6110-based DNA fingerprinting and diagnostic techniques for Mycobacterium tuberculosis complex
    W A Githui
    PHLS Mycobacterium Reference Unit, Dulwich Public Health Laboratory and Department of Microbiology, Kings College School of Medicine and Dentistry, Dulwich Hospital, London, United Kingdom
    J Clin Microbiol 37:1224-6. 1999
    ..tuberculosis complex. In addition, DNA amplification with IS6110-specific primers yielded a 181-bp fragment only in DNA from M. tuberculosis complex isolates...
  19. pmc Evaluation of reverse transcription-PCR and a bacteriophage-based assay for rapid phenotypic detection of rifampin resistance in clinical isolates of Mycobacterium tuberculosis
    I J Eltringham
    PHLS Mycobacterium Reference Unit, Dulwich PHL and Department of Microbiology, King s College School of Medicine and Dentistry, King s College Hospital Dulwich, London SE22 8QF, United Kingdom
    J Clin Microbiol 37:3524-7. 1999
    ....
  20. pmc Outbreak of isoniazid resistant tuberculosis in north London
    M C Ruddy
    HPA Mycobacterium Reference Unit, King s College Hospital Dulwich, Guy s King s and St Thomas Medical School, London SE22 8QF, UK
    Thorax 59:279-85. 2004
    ..A description is given of a major outbreak of isoniazid monoresistant tuberculosis (TB) chiefly in north London, including prisons. The earliest case was diagnosed in 1995 with most cases appearing after 1999...
  21. pmc Human Mycobacterium bovis infections in London and Southeast England
    M J Stone
    National Mycobacterium Reference Laboratory, Health Protection Agency, London, United Kingdom
    J Clin Microbiol 50:164-5. 2012
    ..Low case numbers, despite a substantial animal reservoir, and resolution of all isolates provided no evidence of recent human-to-human transmission or recent significant infection from animals...
  22. doi Rapid molecular detection of tuberculosis and rifampicin drug resistance: retrospective analysis of a national U.K. molecular service over the last decade
    N Seoudi
    Blizard Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University, London, UK
    Thorax 67:361-7. 2012
    ..Fast and reliable detection of Mycobacterium tuberculosis complex (MTBC) and drug resistance is crucial in establishing effective treatment and enforcing timely public health measures...
  23. ncbi The 'bear trap': the colliding epidemics of tuberculosis and HIV in Russia
    F A Drobniewski
    Department of Infectious Diseases, Guy s King s and St Thomas Medical School, East Dulwich Grove, London, UK
    Int J STD AIDS 15:641-6. 2004
    ..Insights gained through the examination of this one region can tell us something of the magnitude of the challenge now faced by both the international community and Russia...
  24. pmc High rates of clustering of strains causing tuberculosis in Harare, Zimbabwe: a molecular epidemiological study
    Philippa J Easterbrook
    Department of HIV GU Medicine, The Guy s, King s and St Thomas s School of Medicine, King s College Hospital, Denmark Hill Campus, London, United Kingdom
    J Clin Microbiol 42:4536-44. 2004
    ..Geographic linkage could be detected in a proportion of these clusters. A small group of actively circulating strains accounted for most of the cases of TB transmission...
  25. pmc Differentiation of tuberculosis strains in a population with mainly Beijing-family strains
    Vladyslav Nikolayevskyy
    Barts and the London School of Medicine, University of London, London, United Kingdom
    Emerg Infect Dis 12:1406-13. 2006
    ..The expanded set of 25 MIRUs provided better discrimination than the original set of 15 (Hunter-Gaston diversity index 0.870 vs. 0.625). Loci MIRU 26, 1982, and 3232 were the most polymorphic in Beijing isolates...
  26. pmc An integrated approach to rapid diagnosis of tuberculosis and multidrug resistance using liquid culture and molecular methods in Russia
    Yanina Balabanova
    National Mycobacterium Reference Laboratory, Institute of Cell and Molecular Sciences, Queen Mary College, Barts and the London School of Medicine, University of London, London, United Kingdom
    PLoS ONE 4:e7129. 2009
    ..To analyse the feasibility, cost and performance of rapid tuberculosis (TB) molecular and culture systems, in a high multidrug-resistant TB (MDR TB) middle-income region (Samara, Russia) and provide evidence for WHO policy change...
  27. ncbi Recommended standards for modern tuberculosis laboratory services in Europe
    F A Drobniewski
    HPA National Mycobacterium Reference Unit and Clinical TB and HIV Group, London, UK
    Eur Respir J 28:903-9. 2006
    ..Improved integration of laboratory medicine as a core part of all tuberculosis programmes is needed to achieve and maximise the potential of new developments...
  28. ncbi Molecular techniques in the diagnosis of Mycobacterium tuberculosis and the detection of drug resistance
    M Caws
    PHLS Mycobacterium Reference Unit, Guy s, King s and St Thomas School of Medicine, King s College Hospital Dulwich, London, UK
    Ann N Y Acad Sci 953:138-45. 2001
    ..Simple phenotypic methods for the detection of resistance to first-line drugs and genotypic kit-form assays for detection of rifampicin resistance have been developed that have become key tools in the containment of MDR TB...
  29. pmc Tuberculosis transmission attributable to close contacts and HIV status, Malawi
    Amelia C Crampin
    London School of Hygiene and Tropical Medicine, Keppel Street, London, United Kingdom
    Emerg Infect Dis 12:729-35. 2006
    ..We estimate that 9%-13% of TB cases were attributable to recent transmission from identifiable close contacts and that nearly half of the TB cases arising from recent infection had acquired the infection from HIV-positive patients...
  30. pmc Rates of latent tuberculosis in health care staff in Russia
    Francis Drobniewski
    Health Protection Agency Mycobacterium Reference Unit and Clinical TB and HIV Group, Institute of Cell and Molecular Sciences, Queen Mary College, University of London, London, United Kingdom
    PLoS Med 4:e55. 2007
    ..The objective of the study was to estimate the prevalence and determine the relative risks and risk factors for infection, within a vertically organised TB service in a country with universal bacille Calmette-Guérin (BCG) vaccination...
  31. pmc Discriminatory ability of hypervariable variable number tandem repeat loci in population-based analysis of Mycobacterium tuberculosis strains, London, UK
    Preya Velji
    Barts and the London School of Medicine, Queen Mary, University of London, London, UK
    Emerg Infect Dis 15:1609-16. 2009
    ..909. Hypervariable loci should be included in standardized panels because they can provide consistent comparable results at multiple settings, provided the proposed conditions are adhered to...
  32. ncbi Antimicrobial prescribing patterns for respiratory diseases including tuberculosis in Russia: a possible role in drug resistance?
    Yanina Balabanova
    KIL Consortium Sustainable TB Service Project, Mycobacterium Reference Unit, Department of Microbiology and Infection, Guy s King s and St Thomas Medical School, King s College, King s College Hospital Dulwich, East Dulwich Grove, London, UK
    J Antimicrob Chemother 54:673-9. 2004
    ..Inappropriate antibiotic prescribing exposes patients to the risk of side effects and encourages the development of drug resistance across antimicrobial groups used for respiratory infections including tuberculosis (TB)...
  33. ncbi Management of multiple drug-resistant tuberculosis
    D C S Hutchison
    Department of Respiratory Medicine, King s College Hospital, London, UK
    Respir Med 97:65-70. 2003
    ..The prognosis for patients treated at specialised centres is good (and better than is generally believed). We describe a new protocol for the detection and management of MDR-TB...
  34. doi Rate of latent tuberculosis infection detected by occupational health screening of nurses new to a london teaching hospital
    Priya Khanna
    Department of Microbiology, Barts and The London National Health Service Trust, London, UK
    Infect Control Hosp Epidemiol 30:581-4. 2009
    ..On multivariate analysis, birth in a country with tuberculosis prevalence of more than 40 cases per 100,000 population was associated with positive results of both the IFN-gamma release assay and the tuberculin skin test...
  35. pmc Mycobacterium tuberculosis and rifampin resistance, United Kingdom
    I Ching Sam
    Health Protection Agency, National Mycobacterium Reference Unit, Institute of Cell and Molecular Science, Barts and the London School of Medicine, 2 Newark Street, London, United Kingdom
    Emerg Infect Dis 12:752-9. 2006
    ..1%, 95.0%, 99.6%, 92.7%, and 99.7%, respectively. The assay enabled earlier diagnosis of MTBC and rifampin resistance (15.2 days) compared with culture-based techniques (30.7 days)...
  36. ncbi High coverage with HAART is required to substantially reduce the number of deaths from tuberculosis: system dynamics simulation
    Rifat A Atun
    Centre for Health Management, Tanaka Business School, Imperial College London, South Kensington Campus, London, UK
    Int J STD AIDS 18:267-73. 2007
    ..High coverage with HAART is required to substantially reduce the number of deaths from tuberculosis...
  37. ncbi Multidrug-resistant tuberculosis in the United Kingdom and Lithuania
    X Gonzalo
    National Mycobacterium Reference Laboratory, Barts and The London, Queen Mary s School of Medicine, London, UK
    Int J Tuberc Lung Dis 18:663-5. 2014
    ..78%). In 2010, the majority of UK patients of Eastern European origin were located within the London region, whereas in 2011 the majority were located outside this region, a significant change (P = 0.01). ..
  38. pmc Use of a phage-based assay for phenotypic detection of mycobacteria directly from sputum
    D J Park
    PHLS Mycobacterium Reference Unit, Public Health Laboratory, King s College Hospital Dulwich, East Dulwich Grove, London SE22 8QF, United Kingdom
    J Clin Microbiol 41:680-8. 2003
    ..tuberculosis organisms in 1 ml of sputum was developed. Taken together, these improvements support the routine application of the assay to sputum specimens...
  39. pmc Can 15-locus mycobacterial interspersed repetitive unit-variable-number tandem repeat analysis provide insight into the evolution of Mycobacterium tuberculosis?
    Andrea Gibson
    Mycobacterium Reference Unit, Health Protection Agency, Barts and The London Queen Mary s School of Medicine and Dentistry, London, United Kingdom
    Appl Environ Microbiol 71:8207-13. 2005
    ..MIRU-VNTR is a valuable tool for phylogenetic studies and could define an evolutionarily uncharacterized population of M. tuberculosis complex organisms...
  40. pmc Analysis of how the health systems context shapes responses to the control of human immunodeficiency virus: case-studies from the Russian Federation
    Rifat A Atun
    Centre for Health Management, Tanaka Business School, Imperial College London, South Kensington Campus, London SW7 2AZ, England, UK
    Bull World Health Organ 83:730-8. 2005
    ..To develop a methodology and an instrument that allow the simultaneous rapid and systematic examination of the broad public health context, the health care systems, and the features of disease-specific programmes...
  41. ncbi Impact of an effective multidrug-resistant tuberculosis control programme in the setting of an immature HIV epidemic: system dynamics simulation model
    Rifat A Atun
    Centre for Health Management, The Business School, Imperial College London, South Kensington Campus, London, UK
    Int J STD AIDS 16:560-70. 2005
    ..The epidemiological starting point for these scenarios is present in many regions within the former Soviet Union and this analysis suggests control of MDRTB should be an urgent priority...
  42. doi Comparison of interferon-gamma release assays and tuberculin skin test in predicting active tuberculosis (TB) in children in the UK: a paediatric TB network study
    Alasdair R J Bamford
    Academic Department of Paediatrics, Imperial College London, London, UK
    Arch Dis Child 95:180-6. 2010
    ..The authors examined the sensitivity of commercially available IGRA to diagnose active TB in children in the UK compared with the tuberculin skin test (TST)...
  43. pmc Increasing antituberculosis drug resistance in the United Kingdom: analysis of National Surveillance Data
    Michelle E Kruijshaar
    Respiratory Diseases Department, Centre for Infections, Health Protection Agency, London NW9 5EQ
    BMJ 336:1231-4. 2008
    ..To identify recent trends in, and factors associated with, resistance to antituberculosis drugs in England, Wales, and Northern Ireland...
  44. pmc Worldwide emergence of extensively drug-resistant tuberculosis
    N Sarita Shah
    Centers for Disease Control and Prevention, Atlanta, Georgia, USA
    Emerg Infect Dis 13:380-7. 2007
    ..9%) met criteria for XDR TB. Further investigation of population-based trends and expanded efforts to prevent drug resistance and effectively treat patients with MDR TB are crucial for protection of public health and control of TB...
  45. ncbi Medical and social analysis of prisoners with tuberculosis in a Russian prison colony: an observational study
    Francis Drobniewski
    Clin Infect Dis 36:234-5. 2003
  46. ncbi Resequencing and association analysis of the SP110 gene in adult pulmonary tuberculosis
    Jeffrey S Szeszko
    Juvenile Diabetes Research Foundation Wellcome Trust Diabetes and Inflammation Laboratory, Cambridge Institute for Medical Research, Department of Medical Genetics, University of Cambridge, WT MRC building, Addenbrooke s Hospital, Cambridge, CB2 2XY, UK
    Hum Genet 121:155-60. 2007
    ..Our results indicate that common polymorphisms of the SP110 gene have no major effect on susceptibility to tuberculosis in this population...
  47. ncbi Origins and properties of Mycobacterium tuberculosis isolates in London
    Jeremy W Dale
    School of Biomedical and Molecular Sciences, University of Surrey, Guildford GU2 7XH, UK
    J Med Microbiol 54:575-82. 2005
    ....
  48. ncbi The importance of recent infection with Mycobacterium tuberculosis in an area with high HIV prevalence: a long-term molecular epidemiological study in Northern Malawi
    Judith R Glynn
    Department of Infectious Diseases, London School of Hygiene and Tropical Medicine, UK
    J Infect Dis 192:480-7. 2005
    ..Here, we present what is, to our knowledge, the first such study in an area with high human immunodeficiency virus (HIV) prevalence...
  49. pmc Snapshot of moving and expanding clones of Mycobacterium tuberculosis and their global distribution assessed by spoligotyping in an international study
    Ingrid Filliol
    Unite de la Tuberculose et des Mycobacteries, Institut Pasteur de Guadeloupe, Pointe a Pitre, Guadeloupe
    J Clin Microbiol 41:1963-70. 2003
    ..Intercontinental matches of shared types among eight continents and subcontinents (Africa, North America, Central America, South America, Europe, the Middle East and Central Asia, and the Far East) are analyzed and discussed...
  50. ncbi Implementing WHO DOTS strategy in the Russian Federation: stakeholder attitudes
    Rifat A Atun
    Centre for Health Management, Tanaka Business School, Imperial College London, South Kensington Campus, London SW7 2PG, UK
    Health Policy 74:122-32. 2005
    ..Cultural issues and capacity constraints, especially in laboratory equipment and personnel, would impede introduction and sustainability of the DOTS strategy...
  51. pmc Evolutionary relationships among strains of Mycobacterium tuberculosis with few copies of IS6110
    Jeremy W Dale
    School of Biomedical and Life Sciences, University of Surrey, Guildford, Surrey GU2 7XH, United Kingdom
    J Bacteriol 185:2555-62. 2003
    ..These lineages appear to be quite distinct from M. tuberculosis isolates with multiple copies of IS6110...
  52. pmc Risk factors for pulmonary tuberculosis in Russia: case-control study
    Richard Coker
    European Centre on Health of Societies in Transition, Department of Public Health and Policy, London School of Hygiene and Tropical Medicine, London WC1E 7HT
    BMJ 332:85-7. 2006
    ..To determine risk factors for pulmonary tuberculosis in Russia...
  53. pmc Health-systems efficiency in the Russian Federation: tuberculosis control
    Katherine Floyd
    Stop TB Department, World Health Organization, Geneva, Switzerland
    Bull World Health Organ 84:43-51. 2006
    ..We also sought to quantify the extent to which efficiency could be improved by reducing hospitalization rates and re-profiling hospital beds available in the tuberculosis-control system...
  54. doi Analysis of association of the TIRAP (MAL) S180L variant and tuberculosis in three populations
    Sergey Nejentsev
    Nat Genet 40:261-2; author reply 262-3. 2008
  55. pmc Global distribution of Mycobacterium tuberculosis spoligotypes
    Ingrid Filliol
    Unite de la Tuberculose et des Mycobacteries, Institut Pasteur, Pointe a Pitre, Guadeloupe, French West Indies
    Emerg Infect Dis 8:1347-9. 2002
    ..The 11708 spoligotypes were clustered into 813 shared types. A total of 1300 orphan patterns (clinical isolates showing a unique spoligotype) were also detected...
  56. pmc Mycobacterium bovis infection, United Kingdom
    Robert M M Smith
    Communicable Disease Surveillance Centre, National Public Health Service for Wales, Abton House, Wedal Road, Cardiff CF14 3QX, Wales, United Kingdom
    Emerg Infect Dis 10:539-41. 2004
    ..This finding suggests that there may be a small risk for transmission to humans, making continued vigilance particularly necessary...
  57. pmc Genetic association and expression studies indicate a role of toll-like receptor 8 in pulmonary tuberculosis
    Sonia Davila
    Infectious Diseases, Genome Institute of Singapore, Singapore, Singapore
    PLoS Genet 4:e1000218. 2008
    ..bovis bacille Calmette-Guérin (BCG). Taken together, our results provide evidence, for the first time, of a role for the TLR8 gene in susceptibility to pulmonary TB across different populations...