S J Docherty

Summary

Affiliation: King's College London
Country: UK

Publications

  1. pmc A genetic association study of DNA methylation levels in the DRD4 gene region finds associations with nearby SNPs
    Sophia J Docherty
    King s College London, MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, De Crespigny Park, Denmark Hill, London, SE5 8AF, UK
    Behav Brain Funct 8:31. 2012
  2. pmc No evidence for association between BMI and 10 candidate genes at ages 4, 7 and 10 in a large UK sample of twins
    Claire M A Haworth
    Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, UK
    BMC Med Genet 9:12. 2008
  3. pmc Applicability of DNA pools on 500 K SNP microarrays for cost-effective initial screens in genomewide association studies
    Sophia J Docherty
    Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, DeCrispigny Park, London, UK
    BMC Genomics 8:214. 2007
  4. pmc A genome-wide association study identifies multiple loci associated with mathematics ability and disability
    S J Docherty
    Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, UK
    Genes Brain Behav 9:234-47. 2010
  5. doi request reprint DNA methylation profiling using bisulfite-based epityping of pooled genomic DNA
    Sophia J Docherty
    King s College London, MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, De Crespigny Park, London SE5 8AF, UK
    Methods 52:255-8. 2010
  6. pmc Generalist genes analysis of DNA markers associated with mathematical ability and disability reveals shared influence across ages and abilities
    Sophia J Docherty
    King s College London, MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, De Crespigny Park, London, SE5 8AF, UK
    BMC Genet 11:61. 2010
  7. pmc Gene-environment interaction in the etiology of mathematical ability using SNP sets
    Sophia J Docherty
    Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College, London SE5 8AF, UK
    Behav Genet 41:141-54. 2011
  8. pmc Bisulfite-based epityping on pooled genomic DNA provides an accurate estimate of average group DNA methylation
    Sophia J Docherty
    Social Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, De Crespigny Park, Denmark Hill, London, SE5 8AF, UK
    Epigenetics Chromatin 2:3. 2009
  9. pmc A three-stage genome-wide association study of general cognitive ability: hunting the small effects
    Oliver S P Davis
    Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, London, UK
    Behav Genet 40:759-67. 2010

Detail Information

Publications9

  1. pmc A genetic association study of DNA methylation levels in the DRD4 gene region finds associations with nearby SNPs
    Sophia J Docherty
    King s College London, MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, De Crespigny Park, Denmark Hill, London, SE5 8AF, UK
    Behav Brain Funct 8:31. 2012
    ..Recent evidence suggests DNA methylation can be influenced by cis-acting DNA sequence variation, that is, DNA sequence variation located nearby on the same chromosome...
  2. pmc No evidence for association between BMI and 10 candidate genes at ages 4, 7 and 10 in a large UK sample of twins
    Claire M A Haworth
    Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, UK
    BMC Med Genet 9:12. 2008
    ..The purpose of the present study was to test the developmental origins of some of these associations in a large longitudinal sample of children...
  3. pmc Applicability of DNA pools on 500 K SNP microarrays for cost-effective initial screens in genomewide association studies
    Sophia J Docherty
    Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, DeCrispigny Park, London, UK
    BMC Genomics 8:214. 2007
    ..We demonstrate that this approach can be effectively applied to the truly genomewide Affymetrix GeneChip Mapping 500 K Array...
  4. pmc A genome-wide association study identifies multiple loci associated with mathematics ability and disability
    S J Docherty
    Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, UK
    Genes Brain Behav 9:234-47. 2010
    ....
  5. doi request reprint DNA methylation profiling using bisulfite-based epityping of pooled genomic DNA
    Sophia J Docherty
    King s College London, MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, De Crespigny Park, London SE5 8AF, UK
    Methods 52:255-8. 2010
    ..This method generates accurate quantitative assessments of group DNA methylation averages, reducing the time, cost and amount of DNA starting material required for large-scale epigenetic investigation of disease phenotypes...
  6. pmc Generalist genes analysis of DNA markers associated with mathematical ability and disability reveals shared influence across ages and abilities
    Sophia J Docherty
    King s College London, MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, De Crespigny Park, London, SE5 8AF, UK
    BMC Genet 11:61. 2010
    ..The 4927 children in this genotyped sample have also been studied at 7, 9 and 12 years of age on measures of mathematical ability, as well as on other cognitive and learning abilities...
  7. pmc Gene-environment interaction in the etiology of mathematical ability using SNP sets
    Sophia J Docherty
    Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College, London SE5 8AF, UK
    Behav Genet 41:141-54. 2011
    ....
  8. pmc Bisulfite-based epityping on pooled genomic DNA provides an accurate estimate of average group DNA methylation
    Sophia J Docherty
    Social Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, De Crespigny Park, Denmark Hill, London, SE5 8AF, UK
    Epigenetics Chromatin 2:3. 2009
    ..Such an approach can be readily applied to the assessment of disease phenotypes reducing the time, cost and amount of DNA starting material required for large-scale epigenetic analyses...
  9. pmc A three-stage genome-wide association study of general cognitive ability: hunting the small effects
    Oliver S P Davis
    Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, London, UK
    Behav Genet 40:759-67. 2010
    ..Larger samples, denser arrays and multiple replications will be necessary in the hunt for the genetic variants that influence human cognitive ability...