Sean C L Deoni

Summary

Affiliation: King's College London
Country: UK

Publications

  1. doi request reprint Magnetic resonance relaxation and quantitative measurement in the brain
    Sean C L Deoni
    Division of Engineering, Brown University, Providence, RI, USA
    Methods Mol Biol 711:65-108. 2011
  2. ncbi request reprint Synthetic T1-weighted brain image generation with incorporated coil intensity correction using DESPOT1
    Sean C L Deoni
    Centre for Neuroimaging Sciences, Institute of Psychiatry, Box P089, London SE5 8AF, UK
    Magn Reson Imaging 24:1241-8. 2006
  3. ncbi request reprint Segmentation of thalamic nuclei using a modified k-means clustering algorithm and high-resolution quantitative magnetic resonance imaging at 1.5 T
    Sean C L Deoni
    Centre for Neuroimaging Sciences, Institute of Psychiatry, King s College London, PO89, De Crespigny Park, Denmark Hill, London, SE5 8AF, UK
    Neuroimage 34:117-26. 2007
  4. doi request reprint Pediatric neuroimaging using magnetic resonance imaging during non-sedated sleep
    Douglas C Dean
    Advanced Baby Imaging Lab, School of Engineering, Brown University, Providence, RI, 02912, USA
    Pediatr Radiol 44:64-72. 2014
  5. doi request reprint Brain differences in infants at differential genetic risk for late-onset Alzheimer disease: a cross-sectional imaging study
    Douglas C Dean
    Advanced Baby Imaging Lab, School of Engineering, Brown University, Providence, Rhode Island
    JAMA Neurol 71:11-22. 2014
  6. pmc Interactions between white matter asymmetry and language during neurodevelopment
    Jonathan O'Muircheartaigh
    Advanced Baby Imaging Laboratory, School of Engineering, Brown University, Providence, Rhode Island 02912, Department of Neuroimaging, King s College London, Institute of Psychiatry, London WC2R 2 LS, United Kingdom, and Alpert Medical School of Brown University, Providence, Rhode Island 02912
    J Neurosci 33:16170-7. 2013
  7. doi request reprint Modeling healthy male white matter and myelin development: 3 through 60months of age
    Douglas C Dean
    Advanced Baby Imaging Lab, School of Engineering, Brown University, Providence, RI 02912, USA Electronic address
    Neuroimage 84:742-52. 2014
  8. pmc Advances in myelin imaging with potential clinical application to pediatric imaging
    Heather S Spader
    Departments of Neurosurgery, Rhode Island Hospital Warren Alpert Medical School of Brown University, Providence, Rhode Island 02903, USA
    Neurosurg Focus 34:E9. 2013
  9. doi request reprint Gleaning multicomponent T1 and T2 information from steady-state imaging data
    Sean C L Deoni
    Centre for Neuroimaging Research, Institute of Psychiatry, King s College London, London UK
    Magn Reson Med 60:1372-87. 2008
  10. pmc Breastfeeding and early white matter development: A cross-sectional study
    Sean C L Deoni
    Advanced Baby Imaging Lab, School of Engineering, Brown University, Providence, RI 02912, USA
    Neuroimage 82:77-86. 2013

Collaborators

Detail Information

Publications22

  1. doi request reprint Magnetic resonance relaxation and quantitative measurement in the brain
    Sean C L Deoni
    Division of Engineering, Brown University, Providence, RI, USA
    Methods Mol Biol 711:65-108. 2011
    ..Finally, the combination of relaxation time data with other quantitative imaging data, including diffusion tensor and magnetization transfer, is examined, with the aim of providing more thorough characterization of brain tissue...
  2. ncbi request reprint Synthetic T1-weighted brain image generation with incorporated coil intensity correction using DESPOT1
    Sean C L Deoni
    Centre for Neuroimaging Sciences, Institute of Psychiatry, Box P089, London SE5 8AF, UK
    Magn Reson Imaging 24:1241-8. 2006
    ..This technique also provides a robust method for signal normalization, which is useful in multicenter longitudinal MR studies of disease progression, and allows the user to reconstruct T(1)-weighted images with arbitrary T(1) weighting...
  3. ncbi request reprint Segmentation of thalamic nuclei using a modified k-means clustering algorithm and high-resolution quantitative magnetic resonance imaging at 1.5 T
    Sean C L Deoni
    Centre for Neuroimaging Sciences, Institute of Psychiatry, King s College London, PO89, De Crespigny Park, Denmark Hill, London, SE5 8AF, UK
    Neuroimage 34:117-26. 2007
    ....
  4. doi request reprint Pediatric neuroimaging using magnetic resonance imaging during non-sedated sleep
    Douglas C Dean
    Advanced Baby Imaging Lab, School of Engineering, Brown University, Providence, RI, 02912, USA
    Pediatr Radiol 44:64-72. 2014
    ..While MRI provides a noninvasive window into the developing brain, MRI of infants and toddlers is challenging due to the modality's extreme motion sensitivity and children's difficulty in remaining still during image acquisition...
  5. doi request reprint Brain differences in infants at differential genetic risk for late-onset Alzheimer disease: a cross-sectional imaging study
    Douglas C Dean
    Advanced Baby Imaging Lab, School of Engineering, Brown University, Providence, Rhode Island
    JAMA Neurol 71:11-22. 2014
    ..Early detection of these alterations holds inherent value for the development and evaluation of preventive treatment therapies...
  6. pmc Interactions between white matter asymmetry and language during neurodevelopment
    Jonathan O'Muircheartaigh
    Advanced Baby Imaging Laboratory, School of Engineering, Brown University, Providence, Rhode Island 02912, Department of Neuroimaging, King s College London, Institute of Psychiatry, London WC2R 2 LS, United Kingdom, and Alpert Medical School of Brown University, Providence, Rhode Island 02912
    J Neurosci 33:16170-7. 2013
    ..The relationship between language ability and asymmetry of myelin stabilized at ∼4 years, indicating anatomical evidence for a critical time during development before which environmental influence on cognition may be greatest. ..
  7. doi request reprint Modeling healthy male white matter and myelin development: 3 through 60months of age
    Douglas C Dean
    Advanced Baby Imaging Lab, School of Engineering, Brown University, Providence, RI 02912, USA Electronic address
    Neuroimage 84:742-52. 2014
    ....
  8. pmc Advances in myelin imaging with potential clinical application to pediatric imaging
    Heather S Spader
    Departments of Neurosurgery, Rhode Island Hospital Warren Alpert Medical School of Brown University, Providence, Rhode Island 02903, USA
    Neurosurg Focus 34:E9. 2013
    ..The authors briefly summarize traditional white matter imaging techniques, describe MCR and mcDESPOT, and discuss current and future clinical applications of MCR, with a particular focus on pediatric epilepsy...
  9. doi request reprint Gleaning multicomponent T1 and T2 information from steady-state imaging data
    Sean C L Deoni
    Centre for Neuroimaging Research, Institute of Psychiatry, King s College London, London UK
    Magn Reson Med 60:1372-87. 2008
    ....
  10. pmc Breastfeeding and early white matter development: A cross-sectional study
    Sean C L Deoni
    Advanced Baby Imaging Lab, School of Engineering, Brown University, Providence, RI 02912, USA
    Neuroimage 82:77-86. 2013
    ....
  11. doi request reprint Transverse relaxation time (T2) mapping in the brain with off-resonance correction using phase-cycled steady-state free precession imaging
    Sean C L Deoni
    Centre for Neuroimaging Research, Institute of Psychiatry, King s College London, London, UK
    J Magn Reson Imaging 30:411-7. 2009
    ..To investigate a new approach for more completely accounting for off-resonance affects in the DESPOT2 (driven equilibrium single pulse observation of T(2)) mapping technique...
  12. pmc Correction of main and transmit magnetic field (B0 and B1) inhomogeneity effects in multicomponent-driven equilibrium single-pulse observation of T1 and T2
    Sean C L Deoni
    Centre for Neuroimaging Research, Institute of Psychiatry, King s College London, London, United Kingdom
    Magn Reson Med 65:1021-35. 2011
    ..The approach was also successfully demonstrated in vivo, with near artifact-free whole-brain, high spatial resolution (1.7 mm × 1.7 mm × 1.7 mm isotropic voxels) myelin water fraction maps acquired in a clinically feasible 16 min...
  13. pmc One component? Two components? Three? The effect of including a nonexchanging "free" water component in multicomponent driven equilibrium single pulse observation of T1 and T2
    Sean C L Deoni
    Advanced Baby Imaging Lab, School of Engineering, Brown University, Providence, Rhode Island 02912, USA
    Magn Reson Med 70:147-54. 2013
    ..It is concluded that this model is preferable for future studies and analysis...
  14. doi request reprint Investigating exchange and multicomponent relaxation in fully-balanced steady-state free precession imaging
    Sean C L Deoni
    Centre for Neuroimaging Research, Institute of Psychiatry, King s College London, London, UK
    J Magn Reson Imaging 27:1421-9. 2008
    ..In many biological tissues (such as white and gray matter), it is well established that the T(2) decay curve is more accurately described by the summation of more than one relaxation species...
  15. pmc Investigating white matter development in infancy and early childhood using myelin water faction and relaxation time mapping
    Sean C L Deoni
    Advanced Baby Imaging Lab, School of Engineering, Brown University, Providence, RI, USA
    Neuroimage 63:1038-53. 2012
    ..Comparison of T(1), T(2) and MWF measurements demonstrates dissimilar sensitivity to tissue changes associated with neurodevelopment, with each providing differential but complementary information...
  16. ncbi request reprint High-resolution T1 mapping of the brain at 3T with driven equilibrium single pulse observation of T1 with high-speed incorporation of RF field inhomogeneities (DESPOT1-HIFI)
    Sean C L Deoni
    Centre for Neuroimaging Research, Institute of Psychiatry, King s College London, London UK
    J Magn Reson Imaging 26:1106-11. 2007
    ..To investigate an alternative approach to correct for flip angle inaccuracies in the driven equilibrium single pulse observation of T1 (DESPOT1) T1 mapping method...
  17. ncbi request reprint Visualization of the deep cerebellar nuclei using quantitative T1 and rho magnetic resonance imaging at 3 Tesla
    Sean C L Deoni
    Oxford Centre for Functional Magnetic Resonance Imaging of the Brain, Oxford, and Centre for Neuroimaging Sciences, Institute of Psychiatry, King s College London, London, UK
    Neuroimage 37:1260-6. 2007
    ..The application of this technique to disorders with cerebellar dysfunction could provide new insight into pathologies like autism and movement disorders...
  18. pmc Quantitative relaxometry of the brain
    Sean C L Deoni
    Centre for Neuroimaging Research, King s College London, Institute of Psychiatry, London, United Kingdom
    Top Magn Reson Imaging 21:101-13. 2010
    ..Finally, the combination of relaxation time data with other complementary quantitative imaging data, including diffusion tensor imaging, is discussed, with the aim of more thoroughly characterizing brain tissue...
  19. ncbi request reprint Quantitative diffusion imaging with steady-state free precession
    Sean C L Deoni
    Imaging Research Laboratories, Robarts Research Institute, London, Ontario, Canada
    Magn Reson Med 51:428-33. 2004
    ..Error within the DESPOD-derived ADC maps was found to be less than 3%, with good precision over a biologically relevant range of ADC values...
  20. ncbi request reprint Visualization of thalamic nuclei on high resolution, multi-averaged T1 and T2 maps acquired at 1.5 T
    Sean C L Deoni
    Imaging Research Laboratories, Robarts Research Institute, London, Ontario, Canada
    Hum Brain Mapp 25:353-9. 2005
    ..These results confirm our hypothesis and demonstrate the potential high-resolution quantitative imaging for nucleus visualization and surgical planning...
  21. ncbi request reprint High-resolution T1 and T2 mapping of the brain in a clinically acceptable time with DESPOT1 and DESPOT2
    Sean C L Deoni
    Imaging Research Laboratories, Robarts Research Institute, 100 Perth Drive, London, Ontario, Canada N6A 5K8
    Magn Reson Med 53:237-41. 2005
    ..7 ms and 6.7 ms. These results demonstrate the clinical feasibility of the methods in the study of neurologic disease...
  22. ncbi request reprint Determination of optimal angles for variable nutation proton magnetic spin-lattice, T1, and spin-spin, T2, relaxation times measurement
    Sean C L Deoni
    Imaging Research Laboratories, Robarts Research Institute, London, Ontario, Canada
    Magn Reson Med 51:194-9. 2004
    ..This new approach, suited for imaging applications where large T1 and T2 ranges are anticipated, provides high and uniform precision over a wide range of T1 and T2 values...