O S P Davis

Summary

Affiliation: King's College London
Country: UK

Publications

  1. pmc A genetic association study of DNA methylation levels in the DRD4 gene region finds associations with nearby SNPs
    Sophia J Docherty
    King s College London, MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, De Crespigny Park, Denmark Hill, London, SE5 8AF, UK
    Behav Brain Funct 8:31. 2012
  2. pmc Bisulfite-based epityping on pooled genomic DNA provides an accurate estimate of average group DNA methylation
    Sophia J Docherty
    Social Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, De Crespigny Park, Denmark Hill, London, SE5 8AF, UK
    Epigenetics Chromatin 2:3. 2009
  3. doi request reprint Visualizing genetic similarity at the symptom level: the example of learning disabilities
    Oliver S P Davis
    MRC Social Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, London SE5 8AF, United Kingdom
    Behav Brain Sci 33:155-7. 2010
  4. pmc A three-stage genome-wide association study of general cognitive ability: hunting the small effects
    Oliver S P Davis
    Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, London, UK
    Behav Genet 40:759-67. 2010
  5. doi request reprint Dramatic increase in heritability of cognitive development from early to middle childhood: an 8-year longitudinal study of 8,700 pairs of twins
    Oliver S P Davis
    Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, De Crespigny Park, London SE5 8AF, United Kingdom
    Psychol Sci 20:1301-8. 2009
  6. pmc Learning abilities and disabilities: generalist genes in early adolescence
    Oliver S P Davis
    Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College, London, UK
    Cogn Neuropsychiatry 14:312-31. 2009
  7. pmc Generalist genes and the Internet generation: etiology of learning abilities by web testing at age 10
    O S P Davis
    Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, London, United Kingdom
    Genes Brain Behav 7:455-62. 2008
  8. pmc A genome-wide association study identifies multiple loci associated with mathematics ability and disability
    S J Docherty
    Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, UK
    Genes Brain Behav 9:234-47. 2010
  9. pmc Genome-wide quantitative trait locus association scan of general cognitive ability using pooled DNA and 500K single nucleotide polymorphism microarrays
    L M Butcher
    Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, London, UK
    Genes Brain Behav 7:435-46. 2008
  10. pmc Visual analysis of geocoded twin data puts nature and nurture on the map
    O S P Davis
    King s College London, MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, London, UK
    Mol Psychiatry 17:867-74. 2012

Detail Information

Publications11

  1. pmc A genetic association study of DNA methylation levels in the DRD4 gene region finds associations with nearby SNPs
    Sophia J Docherty
    King s College London, MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, De Crespigny Park, Denmark Hill, London, SE5 8AF, UK
    Behav Brain Funct 8:31. 2012
    ..Recent evidence suggests DNA methylation can be influenced by cis-acting DNA sequence variation, that is, DNA sequence variation located nearby on the same chromosome...
  2. pmc Bisulfite-based epityping on pooled genomic DNA provides an accurate estimate of average group DNA methylation
    Sophia J Docherty
    Social Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, De Crespigny Park, Denmark Hill, London, SE5 8AF, UK
    Epigenetics Chromatin 2:3. 2009
    ..Such an approach can be readily applied to the assessment of disease phenotypes reducing the time, cost and amount of DNA starting material required for large-scale epigenetic analyses...
  3. doi request reprint Visualizing genetic similarity at the symptom level: the example of learning disabilities
    Oliver S P Davis
    MRC Social Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, London SE5 8AF, United Kingdom
    Behav Brain Sci 33:155-7. 2010
    ..We illustrate this approach using a study of cognitive abilities involving over 5,000 pairs of twins...
  4. pmc A three-stage genome-wide association study of general cognitive ability: hunting the small effects
    Oliver S P Davis
    Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, London, UK
    Behav Genet 40:759-67. 2010
    ..Larger samples, denser arrays and multiple replications will be necessary in the hunt for the genetic variants that influence human cognitive ability...
  5. doi request reprint Dramatic increase in heritability of cognitive development from early to middle childhood: an 8-year longitudinal study of 8,700 pairs of twins
    Oliver S P Davis
    Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, De Crespigny Park, London SE5 8AF, United Kingdom
    Psychol Sci 20:1301-8. 2009
    ..57 and a shared environmental correlation of .65. These findings set constraints on how genetic and environmental variation affects the developing brain...
  6. pmc Learning abilities and disabilities: generalist genes in early adolescence
    Oliver S P Davis
    Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College, London, UK
    Cogn Neuropsychiatry 14:312-31. 2009
    ..A surprising finding emerging from multivariate quantitative genetic studies across diverse learning abilities is that most genetic influences are shared: they are "generalist", rather than "specialist"...
  7. pmc Generalist genes and the Internet generation: etiology of learning abilities by web testing at age 10
    O S P Davis
    Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, London, United Kingdom
    Genes Brain Behav 7:455-62. 2008
    ..In this way, generalist genes may prove invaluable in integrating top-down and bottom-up approaches to the systems biology of the brain...
  8. pmc A genome-wide association study identifies multiple loci associated with mathematics ability and disability
    S J Docherty
    Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, UK
    Genes Brain Behav 9:234-47. 2010
    ....
  9. pmc Genome-wide quantitative trait locus association scan of general cognitive ability using pooled DNA and 500K single nucleotide polymorphism microarrays
    L M Butcher
    Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, London, UK
    Genes Brain Behav 7:435-46. 2008
    ..11 (P < 0.00000003) with g. This shows that future SNP sets that will incorporate many more SNPs could be useful for predicting genetic risk and for investigating functional systems of effects from genes to brain to behavior...
  10. pmc Visual analysis of geocoded twin data puts nature and nurture on the map
    O S P Davis
    King s College London, MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, London, UK
    Mol Psychiatry 17:867-74. 2012
    ..More broadly, our experience demonstrates the potential for collaborative exploratory visualization to act as a lingua franca for large-scale interdisciplinary research...
  11. pmc The heritability of general cognitive ability increases linearly from childhood to young adulthood
    C M A Haworth
    Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, De Crespigny Park, London, UK
    Mol Psychiatry 15:1112-20. 2010
    ....