Affiliation: King's College London
- A public health genetic approach for schizophreniaAndrea Danese
Social, Genetic and Developmental Psychiatry Research Centre, Institute of Psychiatry, King s College, London United Kingdom
Epidemiol Psichiatr Soc 15:185-93. 2006..Schizophrenia is a complex disease resulting from the interplay of genetic and environmental factors. However, psychiatric genetics and epidemiology have often worked as independent research fields...
- Genetic opportunities for psychiatric epidemiology: on life stress and depressionAndrea Danese
Social, Genetic and Developmental Psychiatry SGDP Centre, Institute of Psychiatry, King s College London, De Crespigny Park, Denmark Hill, London SE5 8AF, United Kingdom
Epidemiol Psichiatr Soc 17:201-10. 2008..Genetics can offer new resources to epidemiology. This review will consider recent findings regarding the link between stress and depression as an example to illustrate the added value of employing genetics in epidemiological studies...
- Blunted cortisol responses to stress signal social and behavioral problems among maltreated/bullied 12-year-old childrenIsabelle Ouellet-Morin
Medical Research Council Social, Genetic, and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, London, United Kingdom
Biol Psychiatry 70:1016-23. 2011..Few studies have investigated whether blunted HPA axis reactivity observed in children exposed to early-life stress signals social, emotional, and behavioral problems...
- A discordant monozygotic twin design shows blunted cortisol reactivity among bullied childrenIsabelle Ouellet-Morin
Institute of Psychiatry, King s College London, London
J Am Acad Child Adolesc Psychiatry 50:574-582.e3. 2011....
- Increased pituitary volume in antipsychotic-free and antipsychotic-treated patients of the AEsop first-onset psychosis studyCarmine M Pariante
Stress, Psychiatry and Immunology Laboratory, Division of Psychological Medicine, Clinical Neuropharmacology PO51, Institute of Psychiatry, King s College London, 1 Windsor Walk, Denmark Hill, London SE5 8AF, UK
Neuropsychopharmacology 30:1923-31. 2005..This activation of the hormonal stress response could participate to the important metabolic abnormalities observed in patients with psychosis...
- Adverse childhood experiences, allostasis, allostatic load, and age-related diseaseAndrea Danese
MRC Social, Genetic and Developmental Psychiatry Centre, and Department of Child and Adolescent Psychiatry, Institute of Psychiatry, King s College London, London, UK
Physiol Behav 106:29-39. 2012..Their chronic activation can lead to progressive wear and tear, or allostatic load and overload, and, thus, can exert long-term effects on biological aging and health...
- Childhood maltreatment predicts unfavorable course of illness and treatment outcome in depression: a meta-analysisValentina Nanni
King s College London, Institute of Psychiatry, MRC Social, Genetic, and Developmental Psychiatry Research Centre, UK
Am J Psychiatry 169:141-51. 2012..The authors conducted the first meta-analysis to examine the relationship between childhood maltreatment and these clinically relevant measures of depression...
- Elevated inflammation levels in depressed adults with a history of childhood maltreatmentAndrea Danese
Social, Genetic, and Developmental Psychiatry Centre, PO Box 080, Institute of Psychiatry, King s College London, London SE5 8AF, England
Arch Gen Psychiatry 65:409-15. 2008..The association between depression and inflammation is inconsistent across research samples...
- Work stress precipitates depression and anxiety in young, working women and menMaria Melchior
MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College, London, UK
Psychol Med 37:1119-29. 2007..Rates of depression have been rising, as have rates of work stress. We tested the influence of work stress on diagnosed depression and anxiety in young working adults...