Ian W Craig

Summary

Affiliation: King's College London
Country: UK

Publications

  1. doi request reprint Genetics of human aggressive behaviour
    Ian W Craig
    SGDP Centre, Institute of Psychiatry, Denmark Hill, PO 82, London SE5 8AF, UK
    Hum Genet 126:101-13. 2009
  2. pmc Interaction between specific forms of childhood maltreatment and the serotonin transporter gene (5-HTT) in recurrent depressive disorder
    Helen L Fisher
    MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, Box P080, De Crespigny Park, London SE5 8AF, UK
    J Affect Disord 145:136-41. 2013
  3. ncbi request reprint The importance of stress and genetic variation in human aggression
    Ian W Craig
    Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London PO82, De Crespigny Park, London SE5 8AF, UK
    Bioessays 29:227-36. 2007
  4. ncbi request reprint Influence of life stress on depression: moderation by a polymorphism in the 5-HTT gene
    Avshalom Caspi
    Medical Research Council Social, Genetic, and Developmental Psychiatry Research Centre, Institute of Psychiatry, King s College London, PO80 De Crespigny Park, London, SE5 8AF, UK
    Science 301:386-9. 2003
  5. doi request reprint The interaction between child maltreatment, adult stressful life events and the 5-HTTLPR in major depression
    Robert A Power
    MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, London, UK
    J Psychiatr Res 47:1032-5. 2013
  6. pmc Moderation of breastfeeding effects on the IQ by genetic variation in fatty acid metabolism
    Avshalom Caspi
    Medical Research Council Social, Genetic, and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, London SE5 8AF, England
    Proc Natl Acad Sci U S A 104:18860-5. 2007
  7. pmc A genome-wide association study of social and non-social autistic-like traits in the general population using pooled DNA, 500 K SNP microarrays and both community and diagnosed autism replication samples
    Angelica Ronald
    Social Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, De Crespigny Park, London SE5 8AF, UK
    Behav Genet 40:31-45. 2010
  8. doi request reprint Functional genetic polymorphisms in serotonin and dopamine gene systems and their significance in behavioural disorders
    Ursula M D'Souza
    MRC Social, Genetic and Developmental Psychiatry SGDP Centre, Institute of Psychiatry, King s College London, De Crespigny Park, Denmark Hill, London SE5 8AF, UK
    Prog Brain Res 172:73-98. 2008
  9. pmc The quantification of COMT mRNA in post mortem cerebellum tissue: diagnosis, genotype, methylation and expression
    Emma L Dempster
    Molecular Genetics, Psychological Medicine, Institute of Psychiatry, London, UK
    BMC Med Genet 7:10. 2006
  10. ncbi request reprint A behavioural genomic analysis of DNA markers associated with general cognitive ability in 7-year-olds
    Nicole Harlaar
    Institute of Psychiatry, King s College London, London, UK
    J Child Psychol Psychiatry 46:1097-107. 2005

Collaborators

Detail Information

Publications30

  1. doi request reprint Genetics of human aggressive behaviour
    Ian W Craig
    SGDP Centre, Institute of Psychiatry, Denmark Hill, PO 82, London SE5 8AF, UK
    Hum Genet 126:101-13. 2009
    ..Functional imaging studies of genetic variants affecting serotonin pathways have also provided valuable insights into potential links between genes, brain and aggressive behaviour...
  2. pmc Interaction between specific forms of childhood maltreatment and the serotonin transporter gene (5-HTT) in recurrent depressive disorder
    Helen L Fisher
    MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, Box P080, De Crespigny Park, London SE5 8AF, UK
    J Affect Disord 145:136-41. 2013
    ....
  3. ncbi request reprint The importance of stress and genetic variation in human aggression
    Ian W Craig
    Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London PO82, De Crespigny Park, London SE5 8AF, UK
    Bioessays 29:227-36. 2007
    ....
  4. ncbi request reprint Influence of life stress on depression: moderation by a polymorphism in the 5-HTT gene
    Avshalom Caspi
    Medical Research Council Social, Genetic, and Developmental Psychiatry Research Centre, Institute of Psychiatry, King s College London, PO80 De Crespigny Park, London, SE5 8AF, UK
    Science 301:386-9. 2003
    ..This epidemiological study thus provides evidence of a gene-by-environment interaction, in which an individual's response to environmental insults is moderated by his or her genetic makeup...
  5. doi request reprint The interaction between child maltreatment, adult stressful life events and the 5-HTTLPR in major depression
    Robert A Power
    MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, London, UK
    J Psychiatr Res 47:1032-5. 2013
    ....
  6. pmc Moderation of breastfeeding effects on the IQ by genetic variation in fatty acid metabolism
    Avshalom Caspi
    Medical Research Council Social, Genetic, and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, London SE5 8AF, England
    Proc Natl Acad Sci U S A 104:18860-5. 2007
    ..The finding shows that environmental exposures can be used to uncover novel candidate genes in complex phenotypes. It also shows that genes may work via the environment to shape the IQ, helping to close the nature versus nurture debate...
  7. pmc A genome-wide association study of social and non-social autistic-like traits in the general population using pooled DNA, 500 K SNP microarrays and both community and diagnosed autism replication samples
    Angelica Ronald
    Social Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, De Crespigny Park, London SE5 8AF, UK
    Behav Genet 40:31-45. 2010
    ..When the sample was increased by adding females, 2 additional SNPs were nominally significant (P < .05). These 3 SNPs, however, showed no significant association in transmission disequilibrium analyses of diagnosed ASD families...
  8. doi request reprint Functional genetic polymorphisms in serotonin and dopamine gene systems and their significance in behavioural disorders
    Ursula M D'Souza
    MRC Social, Genetic and Developmental Psychiatry SGDP Centre, Institute of Psychiatry, King s College London, De Crespigny Park, Denmark Hill, London SE5 8AF, UK
    Prog Brain Res 172:73-98. 2008
    ....
  9. pmc The quantification of COMT mRNA in post mortem cerebellum tissue: diagnosis, genotype, methylation and expression
    Emma L Dempster
    Molecular Genetics, Psychological Medicine, Institute of Psychiatry, London, UK
    BMC Med Genet 7:10. 2006
    ..Previous research has suggested that activity and expression of COMT is altered in schizophrenia, and is mediated by one or more polymorphisms within the gene, including the functional Val158Met polymorphism...
  10. ncbi request reprint A behavioural genomic analysis of DNA markers associated with general cognitive ability in 7-year-olds
    Nicole Harlaar
    Institute of Psychiatry, King s College London, London, UK
    J Child Psychol Psychiatry 46:1097-107. 2005
    ..These children have also been studied at 2, 3, 4, and 7 years of age on measures of cognitive and language development and behaviour problems; family environment was also assessed...
  11. ncbi request reprint SNPs, microarrays and pooled DNA: identification of four loci associated with mild mental impairment in a sample of 6000 children
    Lee M Butcher
    Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, London, UK
    Hum Mol Genet 14:1315-25. 2005
    ..Although each SNP accounts for a small amount of variance, their effects are additive and they can be combined in a 'SNP set' that can be used as a genetic risk index for MMI in behavioral genomic analyses...
  12. pmc A longitudinal study of epigenetic variation in twins
    Chloe Chung Yi Wong
    MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, UK
    Epigenetics 5:516-26. 2010
    ..The observation of dynamic changes in DNA methylation over time highlights the importance of longitudinal research designs for epigenetic research...
  13. pmc Utility of the pooling approach as applied to whole genome association scans with high-density Affymetrix microarrays
    Alexandra Schosser
    MRC SGDP Centre, Institute of Psychiatry, King s College London, London, UK
    BMC Res Notes 3:274. 2010
    ..The genotyping assay using the Affymetrix SNP 6.0 array is highly demanding on sample quality due to the small feature size, low redundancy, and lack of mismatch probes...
  14. doi request reprint Association of the dystrobrevin binding protein 1 gene (DTNBP1) in a bipolar case-control study (BACCS)
    Darya Gaysina
    MRC SGDP Centre, Institute of Psychiatry, King s College London, London, UK
    Am J Med Genet B Neuropsychiatr Genet 150:836-44. 2009
    ....
  15. pmc Stressful life events and the serotonin transporter gene (5-HTT) in recurrent clinical depression
    Helen L Fisher
    MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, UK
    J Affect Disord 136:189-93. 2012
    ....
  16. pmc Genes within the serotonergic system are differentially expressed in human brain
    Karen Sugden
    MRC Social, Genetic and Developmental Psychiatry SGDP Centre, Institute of Psychiatry, King s College London, UK
    BMC Neurosci 10:50. 2009
    ..In addition, the effect of genotype and gender on their expression levels was determined...
  17. doi request reprint Depression Case Control (DeCC) Study fails to support involvement of the muscarinic acetylcholine receptor M2 (CHRM2) gene in recurrent major depressive disorder
    Sarah Cohen-Woods
    MRC SGDP Centre, Institute of Psychiatry, King s College London, London, UK
    Hum Mol Genet 18:1504-9. 2009
    ..It is possible our failure to replicate may be a consequence of differences in definition of the MDD phenotype and/or ethnic differences...
  18. doi request reprint Genome-wide association study of co-occurring anxiety in major depression
    Alexandra Schosser
    MRC SGDP Centre, Institute of Psychiatry, King s College London, London, UK
    World J Biol Psychiatry 14:611-21. 2013
    ..In this study we define a quantitative measure of anxiety by summating four anxiety items from the SCAN interview in a large collection of major depression (MDD) cases to identify genes contributing to this complex phenotype...
  19. ncbi request reprint Differential methylation of the X-chromosome is a possible source of discordance for bipolar disorder female monozygotic twins
    Araceli Rosa
    Division of Psychological Medicine, Institute of Psychiatry, King s College London, London, UK
    Am J Med Genet B Neuropsychiatr Genet 147:459-62. 2008
    ....
  20. ncbi request reprint The role of monoamine oxidase A, MAOA, in the aetiology of antisocial behaviour: the importance of gene-environment interactions
    Ian W Craig
    Social, Genetic, and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, P082, De Crespigny Park, London, UK
    Novartis Found Symp 268:227-37; discussion 237-41, 242-53. 2005
    ....
  21. ncbi request reprint Functional effects of a tandem duplication polymorphism in the 5'flanking region of the DRD4 gene
    Ursula M D'Souza
    Medical Research Council Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, Box Number P082, Denmark Hill, London SE5 8AF, United Kingdom
    Biol Psychiatry 56:691-7. 2004
    ..The location of the polymorphism in the 5'regulatory region of the DRD4 gene and the fact that it consists of potential transcription factor binding sites suggest that it might confer differential transcriptional activity of the alleles...
  22. doi request reprint Investigating the genetic variation underlying episodicity in major depressive disorder: suggestive evidence for a bipolar contribution
    Panagiotis Ferentinos
    MRC Social Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, 16 De Crespigny Park, London SE5 8AF, United Kingdom Electronic address
    J Affect Disord 155:81-9. 2014
    ..We aimed to investigate the genetic underpinnings of total depressive episode count in recurrent MDD...
  23. ncbi request reprint Introductory guide to the language of molecular genetics
    Thalia C Eley
    Social, Genetic and Developmental Psychiatry Research Centre, Institute of Psychiatry, London, UK
    J Child Psychol Psychiatry 46:1039-41. 2005
    ..As much of the terminology is specific to the field, this introductory guide aims to aid readers who may be unfamiliar with the approaches of this discipline...
  24. ncbi request reprint Genome-wide linkage analysis of a composite index of neuroticism and mood-related scales in extreme selected sibships
    Matthew W Nash
    MRC Social, Genetic and Developmental Psychiatry Research Centre, Section of Epidemiology, Institute of Psychiatry, King s College, London, UK
    Hum Mol Genet 13:2173-82. 2004
    ..2) around 64 cM (43-70 cM) near marker D1S2892 and another on chromosome 6p (LOD 2.7) around 47 cM (34-63 cM) near marker D6S1610. Further exploratory sex-specific analyses suggested that these QTLs might have sex-limited effects...
  25. ncbi request reprint Application of microarrays to the analysis of the inactivation status of human X-linked genes expressed in lymphocytes
    Ian W Craig
    SGDP Centre, Institute of Psychiatry, Box PO 82, Denmark Hill, London SE5, UK
    Eur J Hum Genet 12:639-46. 2004
    ..Six of the targets were represented by more than one probe set, which gave independent support for the conclusions reached...
  26. ncbi request reprint The genetic basis for sex differences in human behaviour: role of the sex chromosomes
    Ian W Craig
    SGDP Centre, Box PO 82, Institute of Psychiatry, Denmark Hill, London SE5, UK
    Ann Hum Genet 68:269-84. 2004
    ..The review concludes with a summary of the genetic basis for two sexually disparate types of behaviour...
  27. ncbi request reprint Genotyping pooled DNA on microarrays: a systematic genome screen of thousands of SNPs in large samples to detect QTLs for complex traits
    Lee M Butcher
    Social, Genetic and Developmental Psychiatry Centre, Box Number P082, Institute of Psychiatry, De Crespigny Park, London, SE5 8AF, UK
    Behav Genet 34:549-55. 2004
    ..Thus, genotyping pooled DNA on microarrays can provide a systematic and powerful approach for identifying QTL associations for complex traits including behavioral dimensions and disorders...
  28. ncbi request reprint The correlation between reading and mathematics ability at age twelve has a substantial genetic component
    Oliver S P Davis
    1 Department of Genetics, Evolution and Environment, UCL Genetics Institute, University College London, London WC1E 6BT, UK 2 King s College London, Social Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, London SE5 8AF, UK 3
    Nat Commun 5:4204. 2014
    ..Thus, our results highlight the potential role of the learning environment in contributing to differences in a child's cognitive abilities at age twelve. ..
  29. ncbi request reprint X inactivation as a source of behavioural differences in monozygotic female twins
    Caroline S Loat
    Social, Genetic, and Developmental Psychiatry Centre, Institute of Psychiatry, Kings College, London, UK
    Twin Res 7:54-61. 2004
    ....
  30. ncbi request reprint Role of genotype in the cycle of violence in maltreated children
    Avshalom Caspi
    Medical Research Council Social, Genetic, and Developmental Psychiatry Research Centre, Institute of Psychiatry, King s College, London SE5 8AF, UK
    Science 297:851-4. 2002
    ..These findings may partly explain why not all victims of maltreatment grow up to victimize others, and they provide epidemiological evidence that genotypes can moderate children's sensitivity to environmental insults...