Sergi G Costafreda

Summary

Affiliation: King's College London
Country: UK

Publications

  1. ncbi request reprint A systematic review and quantitative appraisal of fMRI studies of verbal fluency: role of the left inferior frontal gyrus
    Sergi G Costafreda
    Brain Image Analysis Unit, Department of Biostatistics and Computing, Institute of Psychiatry, King s College London, London, United Kingdom
    Hum Brain Mapp 27:799-810. 2006
  2. ncbi request reprint Increased inferior frontal activation during word generation: a marker of genetic risk for schizophrenia but not bipolar disorder?
    Sergi G Costafreda
    Institute of Psychiatry, King s College London, London, United Kingdom
    Hum Brain Mapp 30:3287-98. 2009
  3. ncbi request reprint Multisite fMRI reproducibility of a motor task using identical MR systems
    Sergi G Costafreda
    Brain Image Analysis Unit, Institute of Psychiatry, King s College London, UK
    J Magn Reson Imaging 26:1122-6. 2007
  4. ncbi request reprint Predictors of amygdala activation during the processing of emotional stimuli: a meta-analysis of 385 PET and fMRI studies
    Sergi G Costafreda
    Institute of Psychiatry, King s College London, UK
    Brain Res Rev 58:57-70. 2008
  5. ncbi request reprint Bayesian wavelet-based analysis of functional magnetic resonance time series
    Sergi G Costafreda
    Brain Image Analysis Unit, Department of Biostatistics and Computing, Institute of Psychiatry, King s College, DeCrespigny Park, London, UK
    Magn Reson Imaging 27:460-9. 2009
  6. ncbi request reprint A parametric approach to voxel-based meta-analysis
    Sergi G Costafreda
    Institute of Psychiatry, King s College London, UK
    Neuroimage 46:115-22. 2009
  7. pmc Pattern of neural responses to verbal fluency shows diagnostic specificity for schizophrenia and bipolar disorder
    Sergi G Costafreda
    Institute of Psychiatry, King s College London, De Crespigny Park, London UK
    BMC Psychiatry 11:18. 2011
  8. doi request reprint Neural correlates of sad faces predict clinical remission to cognitive behavioural therapy in depression
    Sergi G Costafreda
    Institute of Psychiatry, King s College London, De Crespigny Park, London, UK
    Neuroreport 20:637-41. 2009
  9. doi request reprint Hippocampal atrophy in first episode depression: a meta-analysis of magnetic resonance imaging studies
    James Cole
    Institute of Psychiatry, King s College London, London, UK
    J Affect Disord 134:483-7. 2011
  10. doi request reprint Machine learning classification with confidence: application of transductive conformal predictors to MRI-based diagnostic and prognostic markers in depression
    Ilia Nouretdinov
    Institute of Psychiatry, King s College London, London, UK
    Neuroimage 56:809-13. 2011

Detail Information

Publications21

  1. ncbi request reprint A systematic review and quantitative appraisal of fMRI studies of verbal fluency: role of the left inferior frontal gyrus
    Sergi G Costafreda
    Brain Image Analysis Unit, Department of Biostatistics and Computing, Institute of Psychiatry, King s College London, London, United Kingdom
    Hum Brain Mapp 27:799-810. 2006
    ..The results support distinct dorsal-ventral locations for phonologic and semantic processes within the LIFG. Current limitations to meta-analytic integration of published functional neuroimaging studies are discussed...
  2. ncbi request reprint Increased inferior frontal activation during word generation: a marker of genetic risk for schizophrenia but not bipolar disorder?
    Sergi G Costafreda
    Institute of Psychiatry, King s College London, London, United Kingdom
    Hum Brain Mapp 30:3287-98. 2009
    ..Increased engagement of the inferior frontal cortex during verbal-fluency may thus be a marker of genetic vulnerability to schizophrenia...
  3. ncbi request reprint Multisite fMRI reproducibility of a motor task using identical MR systems
    Sergi G Costafreda
    Brain Image Analysis Unit, Institute of Psychiatry, King s College London, UK
    J Magn Reson Imaging 26:1122-6. 2007
    ..To estimate between-scanner functional MRI (fMRI) reproducibility in a multisite study...
  4. ncbi request reprint Predictors of amygdala activation during the processing of emotional stimuli: a meta-analysis of 385 PET and fMRI studies
    Sergi G Costafreda
    Institute of Psychiatry, King s College London, UK
    Brain Res Rev 58:57-70. 2008
    ..Methodological variables, such as type of analysis and magnet strength, were also independent predictors of amygdala activation...
  5. ncbi request reprint Bayesian wavelet-based analysis of functional magnetic resonance time series
    Sergi G Costafreda
    Brain Image Analysis Unit, Department of Biostatistics and Computing, Institute of Psychiatry, King s College, DeCrespigny Park, London, UK
    Magn Reson Imaging 27:460-9. 2009
    ..Through testing on a combination of simulated and real fMRI data, we show evidence of improved signal recovery, without compromising test accuracy in image space...
  6. ncbi request reprint A parametric approach to voxel-based meta-analysis
    Sergi G Costafreda
    Institute of Psychiatry, King s College London, UK
    Neuroimage 46:115-22. 2009
    ..We illustrate the technique by performing a random-effects meta-analysis of word production. Parametric voxel-based meta-analysis provides a powerful and practical tool for neuroimaging meta-analysis...
  7. pmc Pattern of neural responses to verbal fluency shows diagnostic specificity for schizophrenia and bipolar disorder
    Sergi G Costafreda
    Institute of Psychiatry, King s College London, De Crespigny Park, London UK
    BMC Psychiatry 11:18. 2011
    ..Determining the distinct pattern of neural responses in schizophrenia and bipolar disorder may provide biomarkers for their diagnoses...
  8. doi request reprint Neural correlates of sad faces predict clinical remission to cognitive behavioural therapy in depression
    Sergi G Costafreda
    Institute of Psychiatry, King s College London, De Crespigny Park, London, UK
    Neuroreport 20:637-41. 2009
    ..The functional neuroanatomy of sad faces at the lowest and highest intensities identified patients, before the initiation of therapy, who had a full clinical response to CBT (sensitivity 71%, specificity 86%, P = 0.029)...
  9. doi request reprint Hippocampal atrophy in first episode depression: a meta-analysis of magnetic resonance imaging studies
    James Cole
    Institute of Psychiatry, King s College London, London, UK
    J Affect Disord 134:483-7. 2011
    ..Hippocampal volume loss is particularly evident in patients with recurrent and chronic depression. However, the reports in first episode depression have been mixed...
  10. doi request reprint Machine learning classification with confidence: application of transductive conformal predictors to MRI-based diagnostic and prognostic markers in depression
    Ilia Nouretdinov
    Institute of Psychiatry, King s College London, London, UK
    Neuroimage 56:809-13. 2011
    ..We verify that TCP predictions are as accurate as those obtained with more standard machine learning methods, such as support vector machine, while providing the additional benefit of a valid measure of confidence for each prediction...
  11. doi request reprint Modulation of amygdala response and connectivity in depression by serotonin transporter polymorphism and diagnosis
    Sergi G Costafreda
    Department of Old Age Psychiatry, Institute of Psychiatry, King s College London, UK
    J Affect Disord 150:96-103. 2013
    ..We sought to investigate the effects of genotype as well as diagnosis in patients with depression...
  12. pmc Automated hippocampal shape analysis predicts the onset of dementia in mild cognitive impairment
    Sergi G Costafreda
    King s College London, London, UK
    Neuroimage 56:212-9. 2011
    ..We conclude that automated shape analysis generates sensitive measurements of early neurodegeneration which predates the onset of dementia and thus provides a prognostic biomarker for conversion of MCI to AD...
  13. doi request reprint Modafinil augmentation therapy in unipolar and bipolar depression: a systematic review and meta-analysis of randomized controlled trials
    Alexander J Goss
    School of Medicine and Department of Old Age Psychiatry, King s College London, London, United Kingdom
    J Clin Psychiatry 74:1101-7. 2013
    ..The objective of this study was to examine the efficacy and tolerability of augmentation of first-line therapies with the novel stimulant-like agent modafinil in MDD and bipolar depression...
  14. doi request reprint Neuroanatomy of auditory verbal hallucinations in schizophrenia: a quantitative meta-analysis of voxel-based morphometry studies
    Gemma Modinos
    Department of Psychosis Studies, Institute of Psychiatry, King s College London, London, United Kingdom
    Cortex 49:1046-55. 2013
    ..However, due to differing methodological approaches, the available findings are inconsistent and difficult to integrate...
  15. doi request reprint Predictive neural biomarkers of clinical response in depression: a meta-analysis of functional and structural neuroimaging studies of pharmacological and psychological therapies
    Cynthia H Y Fu
    Institute of Psychiatry, King s College London, De Crespigny Park, London SE5 8AF, UK
    Neurobiol Dis 52:75-83. 2013
    ..We propose that structural and functional neuroimaging show significant potential for the development of prognostic markers of clinical response in the treatment of depression...
  16. ncbi request reprint Pattern classification of sad facial processing: toward the development of neurobiological markers in depression
    Cynthia H Y Fu
    Institute of Psychiatry, King s College London, De Crespigny Park, London, United Kingdom
    Biol Psychiatry 63:656-62. 2008
    ..We sought to examine the sensitivity and specificity of whole brain pattern classification of implicit processing of sad facial expressions in depression...
  17. ncbi request reprint Neuroimaging-based biomarkers in psychiatry: clinical opportunities of a paradigm shift
    Cynthia H Y Fu
    Reader in Neuroimaging and Affective Disorders, Institute of Psychiatry, King s College London, De Crespigny Park, London, England
    Can J Psychiatry 58:499-508. 2013
    ..We conclude that diagnostic and prognostic biomarkers will be developed through the joint application of expert psychiatric knowledge in addition to advanced methods of analysis. ..
  18. pmc Subregional hippocampal deformations in major depressive disorder
    James Cole
    Institute of Psychiatry, King s College London, De Crespigny Park, London, UK
    J Affect Disord 126:272-7. 2010
    ..The present study sought to examine hippocampal volume and subregional morphology in patients with major depressive disorder, who were all medication-free and in an acute depressive episode of moderate severity...
  19. doi request reprint Parametric coordinate-based meta-analysis: valid effect size meta-analysis of studies with differing statistical thresholds
    Sergi G Costafreda
    Department of Old Age Psychiatry, Institute of Psychiatry, King s College London, Box PO 070, De Crespigny Park, SE5 8AF London, UK
    J Neurosci Methods 210:291-300. 2012
    ....
  20. pmc Prognostic and diagnostic potential of the structural neuroanatomy of depression
    Sergi G Costafreda
    Institute of Psychiatry, King s College London, London, UK
    PLoS ONE 4:e6353. 2009
    ..In the present study, we examined the prognostic and diagnostic potential of the structural neural correlates of depression...
  21. ncbi request reprint Effects of ketamine on prefrontal and striatal regions in an overt verbal fluency task: a functional magnetic resonance imaging study
    Cynthia H Y Fu
    Institute of Psychiatry, King s College London, De Crespigny Park, London SE5 8AF, UK
    Psychopharmacology (Berl) 183:92-102. 2005
    ..Glutamatergic dysfunction at N-methyl-D: -aspartate (NMDA) receptors has been proposed as a neurochemical model for schizophrenia. A key feature of this disorder is impairments in cognitive function...